检索结果-南通市图书馆

Exploring the novel role of oligodendrocyte precursor cells in phagocytosis:beyond myelinogenesis

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第2期20卷 473-474页

作者： gen Hamanaka Ken Arai Neuroprotection Research Laboratories Departments of Radiology and NeurologyMassachusetts General Hospital and Harvard Medical SchoolCharlestownMAUSA

Roles of oligodendrocyte precursor cells in the central nervous system:Oligodendrocyte precursor cells(OPCs)have long been recognized for their critical role as precursors to oligodendrocytes,the primary myelin-producing *** precursors,OPCs mature and differentiate into oligodendrocytes,which contribute significantly to the formation of myelin sheaths around *** myelination,which is critical for the conduction of salutatory nerve impulses in the cerebral white matter,underscores the classical role of oligodendrocytes in central nervous system(CNS)***,because oligodendrocytes are differentiated cells that cannot proliferate.

关键词： critical system conduction

Influence of blank holder type on drawability of 5182-O aluminum sheet at room temperature

在线全文

学校读者我要写书评

暂无评论

Transactions of Nonferrous Metals Society of China 2016年第5期26卷 1251-1258页

作者：王游根黄光胜刘定凯陈琳韩廷状彭建潘复生重庆大学材料科学与工程学院机械传动国家重点实验室重庆400044 重庆市科学技术研究院重庆401123

To study the influence of blank holder type on the drawability of 5182-O aluminum sheet at room temperature, the flat blank holder and curved blank holder were employed during the deep drawing process. The microstructures were characterized by optical microscopy （OM）. The results reveal that the limiting drawing ratio （LDR） of 5182-O aluminum alloy sheet is 1.7 using the flat blank holder. The drawn cup have severe earring. Compared with using flat blank holder, the LDR of 5182-O aluminum alloy sheet is enhanced to 2.0 using curved blank holder. In addition, the earring ratio also reduces and flange wrinkling is prevented when the curved blank holder is used. These are due to a more uniform sheet flow in different directions with curved blank holder.

关键词： 5182-O aluminum alloy deep drawing blank holder earring wrinkling

Cross-subcarrier precoder design for massive MIMO-OFDM downlink with symplectic optimization

在线全文

学校读者我要写书评

暂无评论

Science China(Information Sciences) 2025年

作者： Yu-Xuan ZHANG An-An LU Xiang-gen XIA Xi-Qi GAO National Mobile Communications Research Laboratory Southeast University Purple Mountain Laboratories Department of Electrical and Computer Engineering University of Delaware

We propose a cross-subcarrier precoder design(CSPD) for massive multiple-input multiple-output(MIMO) orthogonal frequency division multiplexing(OFDM) downlink. This work aims to significantly improve the channel estimation and signal detection performance by enhancing the smoothness of the frequency domain effective channel. This is accomplished by designing a few vectors known as the transform domain precoding vectors(TDPVs), which are then transformed into the frequency domain to generate the precoders for a set of subcarriers. To combat the effect of channel aging, the TDPVs are optimized under imperfect channel state information(CSI). The optimal precoder structure is derived by maximizing an upper bound of the ergodic weighted sum-rate(WSR) and utilizing the a posteriori beam-based statistical channel model(BSCM). To avoid the large-dimensional matrix inversion, we propose an algorithm with symplectic optimization. Simulation results indicate that the proposed cross-subcarrier precoder design significantly outperforms conventional methods.

关键词：

c-erbB-2、PS2、PSA及DNA含量与乳腺癌神经内分泌分化的相关性研究

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

实用肿瘤杂志 2002年第1期17卷 21-24页

作者：姚根有王丽章锁江浙江大学医学院病理与法医研究所浙江杭州310006 浙江大学医学院电镜室浙江杭州310006

目的　探讨伴神经内分泌 (NE)细胞分化的乳腺癌的恶性程度及生物学行为。方法　用免疫组化法(L SAB)对 131例乳腺癌进行铬粒素 (chromogranin)、c- erb B- 2、PS2及前列腺特异抗原 (PSA)表达检测 ,以经典的Feulgen染色法及图像分析技术... 详细信息

目的　探讨伴神经内分泌 (NE)细胞分化的乳腺癌的恶性程度及生物学行为。方法　用免疫组化法(L SAB)对 131例乳腺癌进行铬粒素 (chromogranin)、c- erb B- 2、PS2及前列腺特异抗原 (PSA)表达检测 ,以经典的Feulgen染色法及图像分析技术对 81例乳腺癌进行 DNA定量分析。结果　 NE细胞阳性乳腺癌 c- erb B- 2阳性表达率为 37.5 %及表达强度 (++～ +++) 33.3%均明显低于 NE细胞阴性肿瘤的 6 2 .6 %和 6 8.7% (P5 C异倍体细胞数以及异倍体率均显著高于 NE细胞 (++)乳腺癌组 (P5 C异倍体细胞数以及异倍体率均明显低于 NE细胞阴性组 (P5 C异倍体细胞数以及异倍体率均显著低于 NE细胞阴性组 (P<0 .0 1)。结论　伴神经内分泌分化的乳腺癌恶性程度较低 ,预后较好。

关键词：乳腺肿瘤神经内分泌学 c-erbB-2 PS2 前列腺特异抗原 DNA倍体

Infiltration by monocytes of the central nervous system and its role in multiple sclerosis: reflections on therapeutic strategies

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第3期20卷 779-793页

作者： Guangyong Zhang Qing Yao Chubing Long Pengcheng Yi Jiali Song Luojia Wu Wei Wan Xiuqin Rao Yue Lin gen Wei Jun Ying Fuzhou Hua Department of Anesthesiology the Second Affiliated Hospital of Nanchang UniversityNanchangJiangxi ProvinceChina Key Laboratory of Anesthesiology of Jiangxi Province NanchangJiangxi ProvinceChina

Mononuclear macrophage infiltration in the central nervous system is a prominent feature of neuroinflammation. Recent studies on the pathogenesis and progression of multiple sclerosis have highlighted the multiple roles of mononuclear macrophages in the neuroinflammatory process. Monocytes play a significant role in neuroinflammation, and managing neuroinflammation by manipulating peripheral monocytes stands out as an effective strategy for the treatment of multiple sclerosis, leading to improved patient outcomes. This review outlines the steps involved in the entry of myeloid monocytes into the central nervous system that are targets for effective intervention: the activation of bone marrow hematopoiesis, migration of monocytes in the blood, and penetration of the blood–brain barrier by monocytes. Finally, we summarize the different monocyte subpopulations and their effects on the central nervous system based on phenotypic differences. As activated microglia resemble monocyte-derived macrophages, it is important to accurately identify the role of monocyte-derived macrophages in disease. Depending on the roles played by monocyte-derived macrophages at different stages of the disease, several of these processes can be interrupted to limit neuroinflammation and improve patient prognosis. Here, we discuss possible strategies to target monocytes in neurological diseases, focusing on three key aspects of monocyte infiltration into the central nervous system, to provide new ideas for the treatment of neurodegenerative diseases.

关键词： blood–brain barrier macrophages monocytes multiple sclerosis neuroinflammation review therapy

Application and Experiment on the Least-action Principle of Explosive Welding of Stainless Steel/Steel

在线全文

学校读者我要写书评

暂无评论

Journal of Iron and Steel Research International 2014年第6期21卷 625-629页

作者： Chang-gen SHI Yu wang Si-jing LI Jun you PLA University of Science and Technology 78138 Troops of PLA

In nature, many physical phenomena follow the least-action principle, which is also abided by the course of explosive welding of stainless steel/steel. The optimal welding interface can be obtained with the least explosive charge by theoretical analysis and interface test. The bonding energy can be acknowledged as the ＂action＂ in explosive welding. To minimize the bonding energy, these rules must be followed such as the lower limit of explosive charge, the upper limit of span and the explosive of critical explosion velocity. The principle of least-action is achieved in the course of explosive welding, and the interface will be optimum.

关键词： explosive welding least-action principle lower limit rule bonding interface

Dyon Solution in Axis Symmetric Spacetime

在线全文

学校读者我要写书评

暂无评论

Chinese Physics Letters 1997年第2期14卷 158-160页

作者： SHEN you-gen CHENG Zong-yi Shanghai Observatory Chinese Academy of SciencesShanghai 200030

By utilizing the method of complex extension in this paper,the rotative axis symmetric solution in the Einstein-Maxwell-conformal scalar field theory is *** solution contains four parameters:scalar charge,electric cha... 详细信息

关键词： solution. charge scalar

Fermion Entropy of Vaidya-Bonner Black Hole

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Physics Letters 2001年第9期18卷 1167-1169页

作者： GAO Chang-Jun SHEN you-gen Shanghai Astronomical Observatory Chinese Academy of SciencesShanghai 200030 National Astronomical Observatories Chinese Academy of SciencesBeijing 100012 Institute of Theoretical Physics Chinese Academy of SciencesBeijing 100080

Using the membrane model which is based on the brick-wall model, we have calculated the free energy and entropy of the Vaidya-Bonner black hole due to fermion fields. The result shows that the entropy of the Vaidya-Bonner black hole is exactly proportional to the area of its event horizon. The relationship between the entropy and event horizon in such a non-static case is just the same as that in a static or stationary cases.

关键词： horizon entropy Vaidya

Robust MMSE precoding for massive MIMO transmission with hardware mismatch

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China(Information Sciences) 2018年第4期61卷 173-186页

作者： Yan CHEN Xiqi GAO Xiang-gen XIA Li you National Mobile Communication Research Laboratory Southeast University Department of Electrical and Computer Engineering University of Delaware

Due to hardware mismatch, the channel reciprocity of time-division duplex massive multipleinput multiple-output system is impaired. Under this condition, there exist several different approaches for base station(BS) to obtain downlink(DL) channel information based on the minimum mean-square-error(MMSE) estimation method. In this paper, we show that with the hardware mismatch parameters BS can obtain the same DL channel information via these different approaches. As the obtained DL channel information is usually imperfect, we propose a precoding technique based on the criterion that minimizes the mean-square-error(MSE) of signal detection at the user terminals(UTs). The proposed precoding is robust to the channel estimation error and significantly improves the system performance compared to the conventional regularized zero-forcing precoding. Furthermore, we derive an asymptotic approximation of the ergodic sum rate for the proposed precoding using the large dimensional random matrix theory, which is tight as the number of antennas both at the BS and UT approach infinity with a fixed non-zero and finite ratio. This approximation can provide a reliable sum rate prediction at a much lower computation cost than Monte Carlo simulations. Simulation results show that the approximation is accurate even for a realistic system dimension.

关键词： robust precoding massive MIMO hardware mismatch channel estimation large dimensional RMT