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Comparing the precision of the pSOFA and SIRS scores in predicting sepsis-related deaths among hospitalized children:a multi-center retrospective cohort study

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World Journal of Emergency Medicine 2022年第4期13卷 259-265页

作者： Chun Zhao Mei-yun Xin jing Li jin-fang Zhao Yu-juan Wang Wei Wang Qian Gao Jie Chen Qi-wei Wang you-peng jin Department of Pediatric Intensive Care Unit Shandong Provincial Hospital Affiliated to Shandong First Medical UniversityJinan 250021China Department of Pediatrics Affiliated Hospital of Jining Medical UniversityJining 272129China Department of Pediatrics Qingdao Women and Children HospitalQingdao 266034China Department of Pediatric Intensive Care Unit Shandong Provincial HospitalCheeloo College of MedicineShandong UniversityJinan 250021China

BACKGROUND:The latest sepsis definition includes both infection and organ failure,as evidenced by the sequential organ failure assessment(SOFA)***,the applicability of the pediatric SOFA score(pSOFA)is not yet *** study evaluated the effectiveness of both pSOFA and system inflammatory reaction syndrome(SIRS)scores in predicting sepsis-related pediatric ***:This is a retrospective multi-center cohort study including hospitalized patientsyouden index(YI),three sub-categories of pSOFA were screened out and a new simplified pSOFA score(spSOFA)was *** effectiveness and accuracy of prediction of pSOFA,SIRS and spSOFA was retrieved from the area under the receiver operating characteristic curve(AUROC)and Delong’s ***:A total of 1,092 participants were eligible for this study,and carried a 23.4%in-hospital mortality *** 24-h elevated pSOFA score(24 h-pSOFA),bloodstream infection,and mechanical ventilation(MV)requirement were major risk factors associated with sepsis-related *** AUROC analysis confirmed that the spSOFA provided good predictive capability in sepsis-related pediatric deaths,relative to the 24 h-pSOFA and ***:The pSOFA score performed better than SIRS in diagnosing infected children with high mortality ***,it is both costly and ***,therefore,proposed spSOFA to accurately predict patient outcome,without the ***,additional investigations,involving a large sample population,are warranted to confirm the conclusion of this study.

关键词： Simple-pSOFA pSOFA Children Mortality Infection SIRS

Field Emission of SiCN Thin Films Bombarded by Ar^+ Ions

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Wuhan University Journal of Natural Sciences 2003年第03A期8卷 829-832页

SiCN thin films were synthesized by a radio frequency chemical vapor deposition (RFCVD) system on P\|type Si (1 0 0) wafers using C 2 H 4 , SiH 4 and N 2 as raw materials. In order to get rid of the oxygen absorbed on the surface and improve the characteristics of electron field emission, Ar + ions of low energy were used to bombard the samples. The field emission characteristics of SiCN thin films before and after Ar + bombardment were studied in the super vacuum environment of 10 -6 Pa. It was showed that the turn\|on field (defined as the point where the current\|voltage curve shows a sharp increase in the current density) decreased from 38 V/μm before bombardment to 25 V/μm after bombardment. And the maximum emission current density increased from 159.2 to 267.4 μA/cm 2 . The composition before and after Ar + bombardment was compared using X\|ray photoelectron spectroscopy (XPS). Our results illustrated that the field emission characteristics were improved after the bombardment of Ar + .

关键词： SiCN thin films RFCVD electron field emission X\|ray photoelectron spectroscopy (XPS)

Efficacy of HA330-II column hemoadsorption in Epstein-Barr virusassociated hemophagocytic lymphohistiocytosis combined with liver failure:A case report

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World Journal of Hematology 2022年第1期9卷 6-12页

作者： Qian Gao Xiao-Wei Xin Chun Zhao Yu-Juan Wang Wei Wang Yi Yin Xiao-Ru Wang you-peng jin Pediatric Intensive Care Unit Shandong Provincial HospitalCheeloo College of MedicineShandong UniversityJinan 250021Shandong ProvinceChina Pediatric Intensive Care Unit Shandong Provincial Hospital Affiliated to Shandong First Medical UniversityJinan 250021Shandong ProvinceChina

BACKGROUND Hemophagocytic lymphohistiocytosis(HLH)is a severe and potentially deadly condition associated with extensive inflammation and immune *** adsorption may serve as a supportive treatment that can stabilize organ function in affected patients by reducing their circulating cytokines *** date,no descriptions of clinical experiences associated with the use of HA330-II column hemoadsorption for the treatment of children affected by HLH have been *** SUMMARY We describe the case of an 11-year-old child with Epstein-Barr virus-associated HLH complicated by liver *** underwent HA330-II column hemoadsorption and chemotherapy and exhibited reductions in levels of inflammatory cytokines,including interleukin(IL),IL-6,IL-8,IL-10,and interferon-γ.The patient’s condition and laboratory parameters gradually improved with *** Hemoadsorption may play an important role in cytokine storm elimination in children with HLH combined with liver failure and consequent multiple organ failure.

关键词： Hemoadsorption HA330-II column Hemophagocytic lymphohistiocytosis Pediatric Liver failure Case report

CaH2-promoted activity of Ni-carbonate interface for CO2 methanation

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Journal of Energy Chemistry 2025年第1期100卷 522-532页

作者： jin-peng Wang Guo-Cui Mao Hui-Lin Jiang Bao-Xia Dong Yun-Lei Teng School of Chemistry and Chemical Engineering Yangzhou University

Transition metal-carbonate interfaces often act as active sites in heterogeneous catalytic *** interface between transition metal and metal carbonate exhibits a dynamic equilibrium during the CO2hydrogenation reaction,involving surface carbonate hydrogenation and ***,there have been few reports on engineering the activity of the interface between transition metal and alkaline earth metal carbonate for catalytic *** work demonstrated that the incorporation of CaH2in Ni/CaCO3enhances the CO2methanation activity of the *** CO2conversion for Ni/CaH2-CaCO3reached 68.5%at 400°C,which was much higher than that of the Ni/CaCO3（31.6%） and Ni/CaH2-CaO （42.4%） ***,the Ni/CaH2-CaCO3catalysts remained stable during the stability test for 24 h at 400°C and 8 *** research revealed that CaH2played a crucial role in promoting the activity of the Ni-carbonate interface for ***2could modify the electronic structure of Ni and tune the structural properties of CaCO3to generate medium basic sites （OH groups）,which are favorable for the activation of H2and ***-situ Fourier transform infrared spectroscopy （FTIR） analysis combined with density functional theory calculations demonstrated that CO2activation occurs at the hydroxyl group （OH） on the CaH2-modified Ni-carbonate surface,leading to the formation of CO3H****,our study has confirmed that CO2methanation over the Ni/CaH2-CaCO3catalysts proceeds via the formate pathway.

关键词： Metal hydride Ni catalysts Carbonate Metal-carbonate interface

Parallel Turing Machine, a Proposal

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Journal of Computer Science & Technology 2017年第2期32卷 269-285页

作者： peng Qu jin Yah you-Hui Zhang Guang R. Gao Department of Computer Science and Technology Tsinghua University Beijing 100084 China Department of Computer Science Brown University Providence RI 02912 U.S.A. Department of Electrical and Computer Engineering University of Delaware Newark DE 19716 U.S.A.

We have witnessed the tremendous momentum of the second spring of parallel computing in recent years. But, we should remember the low points of the field more than 20 years ago and review the lesson that has led to the question at that point whether ＂parallel computing will soon be relegated to the trash heap reserved for promising technologies that never quite make it＂ in an article entitled ＂the death of parallel computing＂ written by the late Ken Kennedy -- a prominent leader of parallel computing in the world. Facing the new era of parallel computing, we should learn from the robust history of sequential computation in the past 60 years. We should study the foundation established by the model of Tuhring machine （1936） and its profound impact in this history. To this end, this paper examines the disappointing state of the work in parallel Turing machine models in the past 50 years of parallel computing research. Lacking a solid yet intuitive parallel Turing machine model will continue to be a serious challenge in the future parallel computing. Our paper presents an attempt to address this challenge by presenting a proposal of a parallel Turing machine model. We also discuss why we start our work in this paper from a parallel Turing machine model instead of other choices.

关键词： parallel Turing machine codelet abstract architecture parallel computing

Nasogastric or nasojejunal feeding in pediatric acute pancreatitis: a randomized controlled trial

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World Journal of Pediatrics 2021年第5期17卷 536-543页

作者： Hong Zhao Yan Han Ke-Rong peng you-you Luo jin-Dan Yu you-Hong Fang Jie Chen jin-Gan Lou Department of Gastroenterology The Children's HospitalZhejiang University School of MedicineHangzhou 310052China National Clinical Research Center for Child Health The Children's HospitalZhejiang University School of MedicineHangzhou 310052China

Background The aim of this study was to compare nasogastric(NG)feeding with nasojejunal(NJ)feeding when treating pediatric patients with acute pancreatitis(AP)..Methods We performed a single-center,prospective,randomized,active-controlled trial involving 77 pediatric patients with AP from April 2014 to December *** patients were randomized into two groups:the NG tube feeding group(34 patients)and the NJ tube feeding group(33 patients).The primary outcome measures included the enteral nutrition intoler-ance,the length of tube feeding time,the recurrent pain of pancreatitis and *** A total of 62 patients with AP(31 patients for each group)came into the final *** differences were found in baseline characteristics,pediatric AP score and computed tomography severity score between the lwo ***(9.7%)patients in the NG group and one(3.2%)patient in the NJ group developed intolerance(relative risk=3.00,95%confidence interval 0.33-27.29,P=0.612).The tube feeding time and length of hospital stay of the NG group were significantly shorter than those of the NJ group(P=0.016 and 0.027,respectively).No patient died in the *** significant differences were found in recurrent pain,complications,nutrition delivery efficacy,and side effects between the two *** NG tube feeding appears to be effective and safe for acute pediatric pancreatitis compared with NJ tube *** addition,high qualifed,large sample sized,randomized controlled trials in pediatric population are needed.

关键词： Acute pancreatitis Enteral nutrition Enteral nutrition intolerance Length of hospital stay Tube feeding time

大剂量紫杉醇联合顺铂腹腔灌注治疗晚期上皮性卵巢癌的临床疗效观察

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实用医院临床杂志 2020年第6期17卷 102-105页

作者：彭友晋王玲玲李飞浪张靖雪四川省广安市人民医院妇科四川广安638000

目的探讨静脉化疗联合腹腔热灌注化疗应用于晚期上皮性卵巢癌(EOC)的临床疗效与安全性。方法回顾性分析108例晚期EOC患者临床资料,单纯静脉给药大剂量紫杉醇+顺铂化疗者纳入对照组(n=61),在此基础上加用顺铂腹腔热灌注化疗者纳入联合组(... 详细信息

目的探讨静脉化疗联合腹腔热灌注化疗应用于晚期上皮性卵巢癌(EOC)的临床疗效与安全性。方法回顾性分析108例晚期EOC患者临床资料,单纯静脉给药大剂量紫杉醇+顺铂化疗者纳入对照组(n=61),在此基础上加用顺铂腹腔热灌注化疗者纳入联合组(n=47)。比较治疗前及治疗6个周期后两组血清肿瘤标志物糖链抗原125(CA125)、高迁移率蛋白A2(HMGA2)、人附睾蛋白4(HE4)水平变化,分析两组短期疗效、生命质量问卷-卵巢癌28(QLQ-OV28)、生存期及6个周期内毒副反应发生情况的差异。结果治疗6个周期后,两组血清CA125、HMGA2、HE4水平均较治疗前有显著下降,且联合组明显低于对照组(P0.05);联合组QLQ-OV28腹部/消化道症状评分及总分均明显低于对照组(P0.05)。结论大剂量紫杉醇静脉化疗联合顺铂腹腔热灌注化疗应用于晚期EOC可取得理想疗效,用药安全性尚可,有利于改善其生活质量并延长生存期。

关键词：紫杉醇顺铂腹腔热灌注晚期上皮性卵巢癌

Expression of Dickkopf-related Protein 1 in Patients with Temporomandibular Osteoarthritis after Treatment with Hyaluronic Acid

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Current Medical Science 2020年第3期40卷 574-579页

作者： Sheng-jun JIANG Zhong-zhi jin you-jian peng Department of Stomatology Renmin Hospital of Wuhan UniversityWuhan430060China

We previously reported that the increased expression of Dickkopf-related protein 1(DKK1)is positively related to vascular endothelial growth factor in the synovial fluid from patients with temporomandibular joint disorders(TMDs).DKK1 is involved in angiogenic activities in the TMD synovium in vitro,but the expression of DKK1 after treatment of TMD-osteoarthritis(TMD-OA)with hyaluronic acid(HA)remains *** this study,we assessed the expression of DKK1 in the synovial fluid of TMD-OA patients before and after treatment with HA via enzyme-linked immunosorbent *** also investigated the role of DKK1 in TMD-OA via immunohistochemical *** relationship between the expression of DKK1 and the clinicopathological characteristics was determined by Pearson *** results showed that the expression of DKK1 was significantly decreased after treatment with *** analyses indicated that the expression of DKK1 in the TMD-OA samples was closely correlated with mouth opening and *** findings suggest that DKK1 could play an important role in the pathogenesis and treatment of *** of the pain by HA treatment may be correlated with the decreased expression of DKK1.

关键词： Dickkopf-related protein 1 temporomandibular joint disorders hyaluronic acid synovial fluid

Influence of Wave Direction on the Dynamic Response of A Submarine Equipment Launch and Recovery System

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China Ocean Engineering 2022年第1期36卷 144-154页

作者： jin Yong-ping XIE Kun LIU Guang-ping WAN Bu-yan peng you-duo National-Local Joint Engineering Laboratory of Marine Mineral Resources Exploration Equipment and Safety Technology Hunan University of Science and TechnologyXiangtan 411201China

A launch and recovery system for a seafloor drill was studied using a dynamic model that considered the influences of seawater resistance and the elastic deformation of the cable based on the lumped mass *** influence of wave direction angle on heave,roll,and pitch motions of the ship was analyzed,and those motion characteristics were then used to assess the tension response of the armored umbilical cable at the lifting point under different wave direction *** analyzing the different wave direction angles we found that,when a ship experiences longitudinal waves it will express longitudinal *** a ship encounters transverse waves,it will have transverse *** oblique waves from bow or stern,a ship will have both longitudinal and transverse movement,exhibiting obvious heave and pitch *** waves,in this study,produced the most obvious impact on armored umbilical cable ***,the tension of the armored umbilical cable will change based on the weight of the armored umbilical cable and the seafloor drill in the *** analysis has provided a useful reference for the study of heave compensation and the constant tension automatic control.

关键词： seafloor drill elastic cable lumped mass method motion characteristics analysis