检索结果-南通市图书馆

添加Ni^2+ 强化 Klebsiella sp.发酵棉秆水解糖液产氢性能

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

化学工程 2020年第6期48卷 1-5,56页

作者：尤少林李艳宾蒋卉张琴安徽工程大学生物与化学工程学院安徽芜湖241000 塔里木大学生命科学学院新疆阿拉尔843300

将不同质量浓度Ni^2+添加至棉秆水解糖液发酵产氢系统,研究了Ni^2+添加对Klebsiella sp.发酵棉秆水解糖液合成生物氢过程的影响。结果表明:在Ni^2+添加质量浓度为20 mg/L处理下,Klebsiella sp.能获得最高的累积产氢量,其发酵120 h的累... 详细信息

将不同质量浓度Ni^2+添加至棉秆水解糖液发酵产氢系统,研究了Ni^2+添加对Klebsiella sp.发酵棉秆水解糖液合成生物氢过程的影响。结果表明:在Ni^2+添加质量浓度为20 mg/L处理下,Klebsiella sp.能获得最高的累积产氢量,其发酵120 h的累积产氢量较之对照组提高约24%。该添加质量浓度下,菌株通过Gompertz方程对累积产氢量拟合的动力学参数——产氢潜力P和最大产氢速率R m值最高,分别可达2957.65 mL/L和22.10 mL/(L·h),延滞期λ最短,仅为2.32 h。该添加质量浓度下,葡萄糖和木糖消耗率、ΔOD 600均值最高,较之对照组分别提高12.5%,5%和14.7%,说明适当质量浓度Ni^2+添加至Klebsiella sp.发酵棉秆水解糖液产氢系统有利于生物氢的合成、还原糖的消耗及菌体的生长。本研究结果为Klebsiella sp.更高效产氢和棉秆水解液更有效转化利用提供了理论基础和技术参考。

关键词： Ni^2+添加 Klebsiella sp. 棉秆水解糖液产氢发酵

急性暴发型溃疡性结肠炎合并特发性血小板减少性紫癜1例

在线全文

学校读者我要写书评

暂无评论

世界华人消化杂志 2009年第3期17卷 340-341页

作者：邵幼林赵卫峰黄小平陈良云甘建和林敏苏州大学附属第一医院感染科江苏省苏州市215006 苏州大学附属第一医院消化科江苏省苏州市215006

患者,男,19岁,因发热15d,便血8d入院.典型的临床表现结合实验室检查、腹部平片和结肠镜下所见诊断为急性暴发型溃疡性结肠炎(UC).入院后患者血小板进行性下降,排除DIC等引起,结合骨髓穿刺结果及激素治疗后迅速缓解疗效,诊断为特发性血... 详细信息

患者,男,19岁,因发热15d,便血8d入院.典型的临床表现结合实验室检查、腹部平片和结肠镜下所见诊断为急性暴发型溃疡性结肠炎(UC).入院后患者血小板进行性下降,排除DIC等引起,结合骨髓穿刺结果及激素治疗后迅速缓解疗效,诊断为特发性血小板减少性紫癜(ITP).急性暴发型UC合并ITP临床罕见.

关键词：溃疡性结肠炎特发性血小板减少性紫癜症状临床治疗

LAM耐药后ADV序贯治疗再耐药HBV变异株的动态变化

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

世界华人消化杂志 2010年第18期18卷 1895-1901页

作者：邵幼林张锁才陈良云吴金华赵卫峰苏州大学附属第一医院感染科江苏省苏州市215006 常州市第三人民医院肝病科江苏省常州市213001

目的:观察阿德福韦酯(ADV)单药序贯治疗拉米夫定(LAM)耐药慢性乙型肝炎(CHB)出现再耐药患者HBV变异株的动态变化.方法:28例初始LAM治疗的CHB患者,出现LAM耐药后换用ADV单药序贯治疗再次出现不充分病毒学应答或病毒学突破.采用实时荧光定... 详细信息

目的:观察阿德福韦酯(ADV)单药序贯治疗拉米夫定(LAM)耐药慢性乙型肝炎(CHB)出现再耐药患者HBV变异株的动态变化.方法:28例初始LAM治疗的CHB患者,出现LAM耐药后换用ADV单药序贯治疗再次出现不充分病毒学应答或病毒学突破.采用实时荧光定量PCR检测DNA,分析HBV DNA动态变化;采用直接PCR产物测序法检测耐药变异,分析变异模式变化.对其中2例患者系列血清进行基因克隆分析其HBV耐药株动态变化.结果:28例入选患者HBVDNA载量随耐药变异株的消长而波动:基线为(7.65±1.04)Log10 copies/mL,LAM疗程中最低值中位数为3.68Log10 copies/mL;出现病毒学突破或/和耐药变异时为(6.87±1.16)Log10 copies/mL,患者换用ADV后最低值中位数为3.78Log10 copies/mL;患者出现耐药变异模式改变或再次病毒学突破时为(6.04±0.93)Log10 copies/mL.治疗基线及两次病毒突破3个时点HBV DNA载量均数逐渐下降,且两两之间差异均有统计学意义.28例患者LAM治疗后24例发生rtM204I/V伴或不伴rtL180M等变异,4例无耐药变异;换用ADV单药序贯治疗出现病毒学突破后,进行测序检测耐药发现:LAM耐药变异13例(包括3例多重耐药),ADV耐药变异11例(包括3例多重耐药),无耐药变异7例.其中11例ADV耐药患者:rtA181V变异6例、rtA181T变异3例、rtN236T变异和rtA181V+rtN236T联合变异各1例.对2例患者血清TA克隆发现ADV耐药准种出现和LAM耐药准种消失的过程,同时发现对ADV耐药的rtI233M变异和对替诺福韦耐药的rtA194T变异.结论:ADV单药序贯治疗LAM耐药CHB出现再耐药患者HBV变异株动态变化存在5种形式,且克隆分析可观察耐药株动态变化过程和发现预存的耐药准种.

关键词：乙型肝炎病毒阿德福韦酯拉米夫定耐药

戊型肝炎肝衰竭患者的血生化指标及血清IL-22表达水平研究

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

传染病信息 2017年第3期30卷 176-178页

作者：习林游绍丽刘鸿凌朱冰臧红辛绍杰荣义辉解放军总医院第一附属医院检验科北京100037 解放军第三〇二医院肝衰竭诊疗与研究中心北京100039 解放军第三〇二医院肝脏肿瘤诊疗与研究中心北京100039

目的研究由HEV感染引起的肝衰竭(hepatic failure,HF)患者肝功能指标特征及血清IL-22水平。方法回顾性分析132例戊型肝炎(戊肝)HF病例资料,按照是否有HBV感染分为混合感染HF组和单纯戊肝HF组,比较2组肝功指标、IL-22、IL-6以及IFN-γ水... 详细信息

目的研究由HEV感染引起的肝衰竭(hepatic failure,HF)患者肝功能指标特征及血清IL-22水平。方法回顾性分析132例戊型肝炎(戊肝)HF病例资料,按照是否有HBV感染分为混合感染HF组和单纯戊肝HF组,比较2组肝功指标、IL-22、IL-6以及IFN-γ水平。以普通戊肝组和健康体检组作对照,比较4组IL-22、IL-6及IFN-γ水平。结果混合感染HF组ALT、TBIL水平高于单纯戊肝HF组(P均<0.05),PA水平低于单纯戊肝HF组(P<0.05)。在IL-22水平方面,戊肝患者均高于健康对照者,混合感染HF组最高,普通戊肝组最低。在IL-6水平方面,HF患者均高于健康对照者,且混合感染HF组最高(P均<0.05),但是普通戊肝组与健康对照组差异无统计学意义。4组IFN-γ差异无统计学意义。结论与单纯戊肝HF患者相比,混合感染HF组肝功能损害程度更严重。戊肝患者IL-22、IL-6水平升高,发生HF时明显升高,合并HBV感染时更高。

关键词：肝衰竭 HBV HEV 血清IL-22

Evaluation of ambient air quality in Guangzhou, China

在线全文

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2007年第4期19卷 432-437页

作者： ZHOU Kai YE you-hua LIU Qiang LIU Ai-jun PENG shao-lin South China Botanical Garden Chinese Academy of Sciences Guangzhou 510650 China. Graduate School of the Chinese Academy of Sciences Beijing 100039 China School of Life Sciences Sun Yat-sen University Guangzhou 510275 China Department of Biology Hainan Normal University Haikou 571158 China Climatic and Agrometeorological Center of Guangdong Province Guangzhou 510080 China

On the basis of the reported air quality index （API） and air pollutant monitoring data provided by the Guangzhou Environment Monitoring Stations over the last twenty-five years, the characteristics of air quality, prominent pollutants, and variation of the average annual concentrations of SOE, NOE, total suspended particulate （TSP）, fine particulates （PM10）, CO and dustfall in Guangzhou City were analyzed. Results showed that TSP was the prominent pollutant in the ambient air environment of Guangzhou City. Of the prominent pollutants, TSP accounted for nearly 62%, SOE 12.3%, and NOx 6.4%, respectively. The average API of Guangzhou over 6 years was higher than that of Beijing, Tianjin, Nanjing, Hangzhou, Suzhou and Shanghai, and lower than that of Shenzhen, Zhuhai and Shantou. Concentrations of air pollutants have shown a downward trend in recent years, but they are generally worse than ambient air quality standards for USA, Hong Kong and EU. SOE and NOx pollution were still serious, impling that waste gas pollution from all kinds of vehicles had become a significant problem for environmental protection in Guangzhou. The possible causes of worsening air quality were also discussed in this paper.

关键词： air pollution index (API) total suspended particulates (TSP) atmospheric quality Guangzhou

Gelation capability of cysteine-modified cyclo(L-Lys-L-Lys)s dominated by Fmoc and Trt protecting groups

在线全文

学校读者我要写书评

暂无评论

Science China Chemistry 2016年第3期59卷 293-302页

作者： Huimin Geng Qianying Zong Jie you lin Ye Aiying Zhang Ziqiang shao Zengguo Feng School of Materials Science and Engineering Beijing Institute of Technology

A series of symmetrical peptidomimetics （3-8） based on cysteine-modified cyclo（L-Lys-L-Lys）s were synthesized, and their gelation capability in organic solvents was dominated by fluorenylmethyloxycarbonyl （Fmoc） and triphenylmethyl （Trt） protecting groups and the exchange of thiol-to-disulfide as well. The peptidomimetics holding Trt （3 and 4） showed no gel performance, while the Fmoc groups promoted 5 and 6 to give rise to thermo-reversible organogels in a number of organic solvents. The self-assembled fibrillar networks were distinctly evidenced in the organogels by transmission electron micros- copy （TEM） and scanning electron microscopy （SEM） observations. Fourier transform infrared spectroscopy （FT-IR） and fluorescence analyses revealed that the hydrogen bonding and ^-rt stacking play as major driving forces for the self-assembly of these organogelators. A 13-turn secondary structure was deduced for the organogel of 6 by virtue of X-ray diffraction, FT-IR and circular dichroism （CD） measurements, and an interdigitated bilayer structure was also presented.

关键词： organogel cyclic dipeptide self-assembly cysteine β-turn

HPV prevalence and genotyping in the cervix of Chinese women

在线全文

学校读者我要写书评

暂无评论

Frontiers of Medicine 2010年第3期4卷 259-263页

作者： shao-Ming WANG Jing LI you-lin QIAO Department of Cancer Epidemiology Cancer Institute of Chinese Academy of Medical SciencesPeking Union Medical CollegeBeijing 100021China

The role of human papillomavirus(HPV)as an etiologic factor of cervical cancer has been firmly established,and prophylactic vaccines are now available and have been approved in many *** implies a promising future for cervical cancer prevention especially for countries with very limited access to ***,the vaccines are not accessible in China's Mainland at the moment,and much needs to be understood about the potential benefit when HPV vaccines are applied to Chinese women,and to make the vaccines more specific to Chinese *** article reviews advanced multi-center,hospital/population-based studies of most recent years,and aims to draw a definitive conclusion on HPV prevalence and genotyping in cervical cancer and precancerous lesions in China from the aspect of study population,geographic areas and time period.

关键词： human papillomavirus(HPV)genotyping cervical cancer precancerous lesions Chinese women

Homogeneous void nucleation in the presence of supersaturated vacancies and interstitials

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Materiomics 2024年第5期10卷 1147-1159页

作者： lin shao Accelerator Laboratory Department of Nuclear EngineeringTexas A&M UniversityCollege StationTX77843USA

Homogeneous void nucleation in metals containing arbitrary vacancies and interstitials has been reexamined,with corrections made to the original work by Katz and *** void size distributions derived previously missed an exponential modification function with void size as the *** a result,void nucleation under a given vacancy supersaturation ratio is underestimated by orders of *** second improvement arises from the accuracy in calculating the vacancy arrival rate to a *** present work proposes establishing a direct relationship between the vacancy arrival rate and the available self-diffusion *** these corrections and improvements,void nucleation in pure Fe is calculated as an example,and an analytic fitting formula is *** required vacancy supersaturation ratio and interstitial-to-vacancy flux ratio for void nucleation calculations can be easily obtained from an analytical solution of rate theory calculations,in which dislocation density and displacements per atom(dpa)rate are adjustable ***,the nucleation rate calculation can be incorporated into rate theory calculations considering evolving dislocation densities,which leads to time-dependent void nucleation.

关键词： Void nucleation Voids Irradiation Swelling Defects

Fe48Co52 Alloy Nanowire Arrays： Effects of Magnetic Field Annealing

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Chemical Physics 2009年第1期22卷 82-86页

作者： Hai-lin Su shao-long Tang Rui-long Wang Yi-qing Chen Chong Jia you-wei Du School of Materials Science and Engineering Hefei University of Technology Hefei 230009 China National Laboratory of Solid State Microstructure and Department of Physics Nanjing University Nanjing 210093 China

The effects of magnetic field annealing on the properties of Fe48Co52 alloy nanowire arrays with various interwire distances （Di=30-60 nm） and wire diameters （Dw=22-46 nm） were investigated in detail. It was found that the array＇s best annealing temperature and crys- talline structure did not show any apparent dependence on the treatment of applying a 3 kOe magnetic field along the wire during the annealing process. For arrays with small Dw or with large Di, the treatment of magnetic field annealing also had no obvious influence on their magnetic performances. However, such a magnetic field annealing constrained the shift of the easy magnetization direction and improved the coercivity and the squareness obviously for arrays with large Dw or with small Di. The difference in the intensity of the effective anisotropic field within the arrays was believed to be responsible for this different variation of the array＇s magnetic properties after magnetic field annealing.

关键词： FeCo alloy, Nanowire array, Magnetic field annealing, Magnetic property Effective anisotropie field