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Radial Pulse and Electrocardiography Modulation by Mild Thermal Stresses Applied to Feet: An Exploratory Study with Randomized, Crossover Design

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Chinese Journal of Integrative Medicine 2020年第4期26卷 299-306页

作者： Jang-han bae Boncho Ku young Ju Jeon Hyunho Kim Jihye Kim Haebeom Lee Jong Yeol Kim Jaeuk U.Kim Korea n Medici ne Fun dame ntal Research Divisi on Korea Institute of Oriental MedicineDaejeon(34054)Republic of Korea Department of Biofunctional Medicine and Diagnostics College of Korea n MedicineKyung Hee UniversitySeoul(02453)Republic of Korea Department of Human Informatics of Korean Medicine Interdisciplinary ProgramsKyung Hee UniversitySeoul(02453)Republic of Korea

Objective:To investigate the changes in radial pulse induced by thermal stresses(TSs).Methods:Sixty subjects were *** an open-label,2x2 crossover randomization design,both feet of each subject were immersed in 15%:water for cold stress(CS)and in 40 X:water for heat stress(HS)for 5 min *** pulse,respiration and electrocardiogram(ECG)signals were recorded before,during and immediately after the ***:The an alysis of heart rate variability revealed that CS in creased the low-freque ncy(LF)and high-frequency(HF)components(P<0.05)and that HS reduced the LF and HF components(P<0.01).Both TSs reduced the normalized LF,increased the normalized HF,and reduced the LF/HF *** differences in the ECG signals were more dominant during the TS sessions,but those in the radial pulse signals became more domi nant immediately after the TS sessi *** decreased the pulse depth(P<0.01)and in creased the radial augme ntation in dex(P<0.1),and HS in creased the pulse pressure(P<0.1)and sube ndocardial viability ratio(P<0.01).There were no significant differences in pulse rate during the three time sequences of each *** respiration rate was increased(P<0.1),and the pulse rate per respiration(P/R ratio)was significantly decreased(P<0.05)with *** HF region(10-30 Hz)of the pulse spectral density was suppressed during both ***:CS induced vasoconstriction and sympathetic reactions,and HS induced vasodilation and parasympathetic reacti *** on defi nitions used in pulse diag no sis,we made the novel discoveries that the pulse became slower(decreased P/R ratio),more floating and tenser under CS and that the HF region of the spectral power decreased significantly under both TSs.

关键词： radial pulse pulse diag no sis thermal stress electrocardiography heart rate variability

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Sexual function and psychological characteristics ofpenile paraffinoma

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Asian Journal of Andrology 2003年第3期5卷 191-194页

作者： Du Geon Moon Jeong Woo Yoo Jae Hyun bae Chang Su han Yong Ku Kim Je Jong Kim Department of Urology Korea University College of Medicine Seoul 136705 KoreaDepartment of Urology Korea University College of Medicine Seoul 136705 KoreaDepartment of Urology Korea University College of Medicine Seoul 136705 KoreaDepartment of Psychiatry Korea University College of Medicine Seoul 136705 KoreaDepartment of Psychiatry Korea University College of Medicine Seoul 136705 KoreaDepartment of Urology Korea University College of Medicine Seoul 136705 Korea

Aim: To identify the sexual, emotional and psychological status of men who augmented their penis with mineral oil injection for their small penis. Methods: Men who had penile paraffin were asked to answer the semi-structured questionnaire. The questionnaire was designed to assess the motivation, method of penile injection, changes in erectile function and satisfaction after penile injection. SCL (Symptom checklist)-90-R, STAI (State and Trait Anxiety Inventory) and Zung SDS (Self-rating depression scale) were also included in the questionnaire for psychological evaluation. Results: A total of 357 men completed the questionnaire. The first-ranked motivation of the injection was recommendation by their acquaintances (48.9 %). The majority of the respondents had the procedure by non-medical person (78.0 %). Before injection, 17.2 % had a sense of inferiority in their penis and 32 % worried about their weak erectile function. After injection, 33.0 % have found relief from their sense of inferiority and 17.8 % wish to feel improvement in their erectile function. Most of the respondents (91 %) were not satisfied with their penis and 74 % of them replied that they want to remove the injected material. Only 15.6 % did not experience side effects. Most of the subjects have suffered from various side effects such as inflammation, skin necrosis, pain, etc. No evidence of psychiatric pathology was found in psychological evaluation. Conclusion: The motivations of mineral oil injection were recommendation by their acquaintances or desire to be more mannish. Most of them had suffered from various side effects and only a small number of them felt improvement in their sense of inferiority, in their penis and erectile function. Increased public awareness is needed for the prevention of this physically and psychologically debilitating problem.

关键词： paraffinoma penis augmentation psychology

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Uncovering material deformations via machine learning combined with four-dimensional scanning transmission electron microscopy

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npj Computational Materials 2022年第1期8卷 1072-1080页

作者： Chuqiao Shi Michael C.Cao Sarah M.Rehn Sang-Hoon bae Jeehwan Kim Matthew RJones David A.Muller Yimo han Department of Materials Science and NanoEngineering Rice UniversityHoustonTXUSA School of Applied and Engineering Physics Cornell UniversityIthacaNYUSA Department of Chemistry Rice UniversityHoustonTXUSA Department of Mechanical Engineering and Materials Science Washington University in Saint LouisSaint LouisMOUSA Institute of Materials Science and Engineering Washington University in Saint LouisSaint LouisMOUSA Department of Mechanical Engineering Massachusetts Institute of TechnologyCambridgeMAUSA Kavli Institute for Nanoscale Science Cornell UniversityIthacaNYUSA

Understanding lattice deformations is crucial in determining the properties of nanomaterials,which can become more prominent in future applications ranging from energy harvesting to electronic ***,it remains challenging to reveal unexpected deformations that crucially affect material properties across a large sample ***,we demonstrate a rapid and semi-automated unsupervised machine learning approach to uncover lattice deformations in *** method utilizes divisive hierarchical clustering to automatically unveil multi-scale deformations in the entire sample flake from the diffraction data using four-dimensional scanning transmission electron microscopy(4D-STEM).Our approach overcomes the current barriers of large 4D data analysis without a priori knowledge of the *** this purely data-driven analysis,we have uncovered different types of material deformations,such as strain,lattice distortion,bending contour,etc.,which can significantly impact the band structure and subsequent performance of nanomaterials-based *** envision that this data-driven procedure will provide insight into materials’intrinsic structures and accelerate the discovery of materials.

关键词： utilize purely overcome

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Knowledge and Attitudes of Oncology Nurses Toward Clinical Trials-A Secondary Publication

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Journal of Clinical and Nursing Research 2024年第1期8卷 209-221页

作者： Jin Sil bae Jeong Hye Kim Department of Nursing Asan Medical CenterSeoulSouth Korea Department of Clinical Nursing University of UlsanSeoul 05505Korea

Purpose:The purpose of this study was to identify the knowledge and attitudes of oncology nurses toward clinical trials and to provide evidence for the development of clinical trial education programs for oncology ***:The study was conducted on 142 nurses who had more than six months of nursing experience working with cancer patients at a tertiary hospital in Seoul,Korea.A structured questionnaire was used to measure the knowledge and attitudes of oncology nurses toward clinical ***:The participants scored an average of 15.03±3.52 out of 19 in terms of knowledge about clinical *** terms of attitudes toward clinical trials,the participants scored an average of 5.91±1.37 out of *** was a significant positive correlation between the knowledge and attitudes of the participants toward clinical trials(r=0.23,P=0.007).Conclusion:This study found that there was a relationship between the knowledge and attitudes of oncology nurses toward clinical *** improve the competency of oncology nurses and provide high-quality care to patients participating in clinical trials,more systematic and sustainable education is required.

关键词： Clinical trial Nurses Knowledge Attitude Neoplasms

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Effects of torrefied wood chip and vermicompost application on vegetation growth and nutrient uptake in the Saemangeum reclaimed land

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Ecological Processes 2020年第1期9卷 74-82页

作者： Aung Aung Jeong Min Seo Si Ho han Ji young An Huong Thi Thuy Dao Woo Bin youn Byung bae Park Department of Environment and Forest Resources College of Agriculture and Life SciencesChungnam National University99 Daehak-roYuseong-guDaejeon 34134Republic of Korea Environmental Conservation Department Ministry of Natural Resources and Environmental ConservationNaypyitaw 15011Myanmar Institute of Agricultural Science College of Agriculture and Life SciencesChungnam National University99 Daehak-roYuseong-guDaejeon 34134Republic of Korea.

Background:In reclaimed land,the growth environment for plants may be unfavorable and the initial establishment and growth of seedlings could be limited because of low nutrient and water *** and control of understory vegetation that competes with seedlings may be of help in ameliorating soil physical and chemical properties,resulting in better seedling growth and reclamation ***,the amount of nutrients understory vegetation absorbs in this ecological process has been rarely ***,we aimed to investigate the effect of soil amendment on biomass production and nutrient uptake by weeds in the nutrient-poor reclaimed *** applied three levels of torrefied wood chip(TWC;0,2.5,and 5 Mg ha^(−1))and two levels of vermicompost(VC;0 and 2.7 Mg ha^(−1))as soil physical improvements and organic soil amendments in reclaimed land in the Republic of Korea,with Populus euramericana used as the crop ***:TWC did not influence weed biomass,but 2.7 Mg ha^(−1) VC significantly increased weed biomass by 21%compared to 0 Mg ha^(−1) VC ***(N),phosphorus(P),potassium(K),calcium(Ca),magnesium(Mg),and sodium(Na)concentrations in weeds were the highest in control,but there was no statistical difference among ***,VC treatment did marginally increase nutrient uptake in weeds,especially P,K,Ca,and *** treatments influenced crop tree ***:We conclude that VC can be used as an organic source of nutrients in reclaimed soil and that weed management is necessary to increase treatment effects on crop trees in this salt-affected reclaimed land.

关键词： Nutrient content Populus euramericana Saemangeum Soil amendment Weed biomass

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Effect of tellurium on the microstructure and mechanical properties of Fe-14Cr oxide-dispersion-strengthened steels produced by additive manufacturing

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Journal of Materials Science & Technology 2021年第36期95卷 114-126页

作者： Barton Mensah Arkhurst Jee Hwan bae Min young Na Hye Jung Chang Hyun Gil Kim Il Hyun Kim Ho Jin Ryu Jeoung han Kim School of Materials Science and Engineering University of New South Wales SydneyNSW 2052Australia Advanced Analysis Center Korea Institute of Science and Technology SeoulSeongbuk-guRepublic of Korea LWR Fuel Technology Division Korea Atomic Energy Research InstituteDaejeonYuseong-guRepublic of Korea Department of Nuclear and Quantum Engineering KAISTDaejeonYuseong-guRepublic of Korea Department of Materials Science&Engineering Hanbat National UniversityRepublic of Korea

Conventionally,Te has primarily been used to improve the machinability of steel and its *** this work,Te was used to refine the grains of an oxide-dispersion-strengthened(ODS)steel produced by additive manufacturing(AM)with fixed processing *** of Te to the raw powder produced an ODS steel with a fine-grained microstructure,in contrast to the ODS steel manufactured without ***,the addition of Te resulted in superior yield strength and ultimate tensile strength,which was attributed to the combined effects of grain refinement and the finer nanoparticles(NPs)composed of Terich composite NPs and Cr-rich *** the first time,the AM technique was used to obtain grain and nanoparticle sizes of~3.4μm and 6 nm,respectively,from the Te-added ODS steel.

关键词： Additive manufacturing Directed energy deposition Oxide-dispersion-strengthened steel Nanoparticle Tellurium

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Mesenchymal stem cells for enhancing biological healing after meniscal injuries

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World Journal of Stem Cells 2021年第8期13卷 1005-1029页

作者： Hye Chang Rhim Ok Hee Jeon Seung-Beom han Ji Hoon bae Dong Won Suh Ki-Mo Jang T.H.Chan School of Public Health Harvard UniversityBostonMA 02115United States Department of Biomedical Sciences Korea University College of MedicineSeoul 02841SeoulSouth Korea Department of Orthopaedic Surgery Anam HospitalKorea University College of MedicineSeoul 02841SeoulSouth Korea Department of Orthopaedic Surgery Guro HospitalKorea University College of MedicineSeoul 08308SeoulSouth Korea Department of Orthopaedic Surgery Barunsesang HospitalSeongnam 13497South Korea

The meniscus is a semilunar fibrocartilage structure that plays important roles in maintaining normal knee biomechanics and *** roles of the meniscus,including load distribution,force transmission,shock absorption,joint stability,lubrication,and proprioception,have been well *** to the meniscus can disrupt overall joint stability and cause various symptoms including pain,swelling,giving-way,and *** treated properly,it can lead to early degeneration of the knee *** meniscal injuries remain a significant challenge due to its low intrinsic healing potential,most notably in avascular and aneural inner two-thirds of the area,more efficient repair methods are *** stem cells(MSCs)have been investigated for their therapeutic potential in vitro and in *** far,the application of MSCs,including bone marrow-derived,synovium-derived,and adipose-derived MSCs,has shown promising results in preclinical studies in different animal *** preclinical studies could be categorized into intra-articular injection and tissueengineered construct application according to delivery *** promising results in preclinical studies,there is still a lack of clinical *** review describes the basic knowledge,current treatment,and recent studies regarding the application of MSCs in treating meniscal *** directions for MSC-based approaches to enhance meniscal healing are suggested.

关键词： Meniscus Meniscus healing Cell-based treatment Mesenchymal stem cell Tissue engineering

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Successful treatment of multiple hepatocellular adenomas with percutaneous radiofrequency ablation

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World Journal of Gastroenterology 2013年第42期19卷 7480-7486页

作者： Sun young Ahn Soo young Park young Oh Kweon Won young Tak han Ik bae Seung Hyun Cho Department of Internal Medicine Kyungpook National University HospitalDaegu 700-721South Korea Department of Pathology Kyungpook National University HospitalDaegu 700-721South Korea Department of Radiology Kyungpook National University HospitalDaegu 700-721South Korea

Hepatocellular adenoma (HCA) is one of the important complications of glycogen storage disease type?Ia (GSD-Ia) because it can be transformed into hepatocellular carcinoma. Although surgical resection is a standard treatment of choice for solitary HCA, multiple HCAs in GSD-Ia patients present as therapeutic challenges for curative treatment. Therefore, treatment strategy according to malignant potential is important in management of HCAs in GSD-Ia. The authors present a case of histologically proven multiple HCAs without β-catenin mutations occurred in a GSD-Ia patient treated successfully with percutaneous radiofrequency ablation as a minimally invasive therapy.

关键词： Glycogen storage disease Hepatocellular adenoma Radiofrequency ablation β-catenin activation Glycogen storage disease

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Sex as an effect modifier in the association between alcohol intake and gastric cancer risk

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World Journal of Gastrointestinal Oncology 2021年第5期13卷 453-461页

作者： Jong-Myon bae Department of Preventive Medicine Jeju National University College of MedicineJeju-si 63243JejuSouth Korea

BACKGROUND The results of previous meta-analyses evaluating the association between the alcohol intake and gastric cancer risk have reported that a statistical significance only for *** To investigate the different association between alcohol intake and gastric cancer risk between men and *** The selection criteria included a prospective cohort study for evaluating alcohol intake and gastric cancer risk,with relative risks adjusted for potential *** relative risk(RR)for the potential confounders and its 95%confidence interval(CI)in the highest vs lowest level were extracted from each study and a random-effects meta-analysis was *** analyses by region,level of adjustment for smoking status,adjusting for body mass index,and year of publication were *** A meta-analysis of all 27 cohorts showed that alcohol intake increased the risk of gastric cancer(summary RR=1.13,95%CI:1.04-1.23,I2=58.2%).Further,13 men’s cohorts had higher summary RR while maintaining statistical significance,and only seven women’s cohorts had no statistical *** The present review suggests that alcohol consumption increases the risk of gastric cancer in *** findings showed that the sex variable in the association between alcohol intake and gastric cancer risk seemed to be an effect modifier with an interaction *** is necessary to re-estimate follow-up outcomes after stratifying for sex.

关键词： Alcohol Stomach neoplasm Effect modifier Cohort studies Meta-analysis Risk factors

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Inverse Kinematics Analysis and COG Trajectory Planning Algorithms for Stable Walking of a Quadruped Robot with Redundant DOFs

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Journal of Bionic Engineering 2018年第4期15卷 610-622页

作者： Hyunkyoo Park Bokeon Kwak Joonbum bae LG-electronics Seou108592 Republic of Korea Department of Mechanical Engineering Ulsan National Institute of Science and Technology Ulsan 44919 Republic of Korea

This paper presents a new Center of Gravity （COG） trajectory planning algorithm for a quadruped robot with redundant Degrees of Freedom （DOFs）. Each leg has 7 DOFs, which allow the robot to exploit its kinematic redundancy for various locomotion and manipu- lation tasks. Also, the robot can suitably adapt to different environment （e.g., passing through a narrow gap） by simply changing the body posture. However, the robot has significant COG movement during the leg swinging phase due to the heavy leg weights; the weight of all the four legs takes up 80% of the robot＇s total weight. To achieve stable walking in the presence of undesired COG movements, a new COG trajectory planning algorithm was proposed by using a combined Jacobian of COG and centroid of a support polygon including a foot contact constraint. Additionally, the inverse kinematics of each leg was solved by modified improved Jacobian pseudoinverse （mIJP） algorithm. The mIJP algorithm could generate desired trajectories for the joints even when the robot＇s leg is in a singular posture. Owing to these proposed methods, the robot was able to perform various modes of locomotion both in simulations and experiments with improved stability.

关键词： legged robot redundant degree-of-freedoms stable walking center-of-gravity planning

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