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Changes in interleukin-6 levels in saliva in patients with oral squamous cell carcinoma during the treatment phase.

中国口腔颌面外科杂志 2008年第B5期6卷 150-151页

作者： Jun Goto Ayako Harahashi Yutaka Yamazaki Akira Satoh yoshimasa kitagawa Oral Diagnosis and Medicine Department of OralPathobiological Science Hokkaido University Graduate Schoolof Dental Medicine. Sapporo Japan

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Preoperative lymph node staging of oral cancer with FDG-PET

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中国口腔颌面外科杂志 2008年第B5期6卷 72-73页

作者： yoshimasa kitagawa Yutaka Yamazaki Hironobu Hata Ken-ichi Oral Notani Nagara Tamaki Oral Diagnosis and Medicine Oral Diagnosis and Medicine Hokkaido University Sapporo 060-8586 Japan Diagnosis and Medicine Oral Diagnosis and Medicine Nuclear Medicine Hokkaido University Sapporo 060-8586 Japan

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Evaluation of an oral moisture-checking device for screening dry mouth

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Open Journal of Stomatology 2013年第8期3卷 440-446页

作者： Yosuke Fukushima Tetsuya Yoda Shoichiro Kokabu Ryuichiro Araki Tsubasa Murata yoshimasa kitagawa Ken Omura Shuji Toya Kayoko Ito Saori Funayama Hiroshi Iwabuchi Kazuhiro Asano Yutaka Imai Akihide Negishi Satoshi Yokoo Goichi Matsumoto Eiro Kubota Hideki Watanabe Mikio Kusama Kojiro Onizawa Takuya Goto Seiji Nakamura Ryuichi Nakazawa Kiyoshi Harada Takashi Fujibayashi Community Health Science Center Saitama Medical University Saitama Japan Department of Dentistry and Oral Surgery Tochigi National Hospital Tochigi Japan Department of Oral and Maxillofacial Surgery Division of Medicine Interdisciplinary Graduate School of Medicine and Engi- neering Univer-sity of Yamanashi Kofu and Tamaho Japan Department of Oral and Maxillofacial Surgery Dokkyo Medical University School of Medicine Tochigi Japan Department of Oral and Maxillofacial Surgery Faculty of Medicine Sai-tama Medical University Saitama Japan Department of Oral and Maxillofacial Surgery Institute of Clinical Medicine University of Tsukuba Tsukuba Japan Department of Oral and Maxillofacial Surgery Jichi Medical University Tochigi Japan Department of Oral and Maxillofacial Surgery Kanagawa Dental College Yokosuka Japan Department of Stomatology and Oral Surgery Gunma University Graduate School of Medicine Maebashi Japan Division of Gereatric Dentistry Niigata University Medical & Dental Hospital Niigata Japan Oral and Maxillofacial Surgery Dry Mouth Clinic The Nippon Dental University Niigata Hospital Niigata Japan Oral Diagnosis and Medicine Department of Oral Pathobiological Science Graduate School of Dental Medicine Hokkaido University Sapporo Japan Oral Surgery Department of Oral Restitution Division of Oral Health Sciences Graduate School Tokyo Medical and Dental University Tokyo Japan Section of Oral and Maxillofacial Oncology Division of Maxillofacial Diagnostic and Surgical Sciences Faculty of Dental Science Kyushu University Fukuoka Japan

Objective: This multicenter clinical study was to assess the clinical usability of an oral moisture-checking device in detecting the dry mouth patients and evaluating the optimal measurement site. Materials and Methods: The study group comprised 250 patients with dry mouth and 241 healthy volunteer subjects at 13 medical centers. This device was used to measure the moisture degrees of the lingual mucosa and the buccal mucosa. Subjective oral dryness, objective oral dryness, and saliva flow rates were also compared between the two groups. For statistical analysis, receiver-operating characteristic analysis was performed to calculate the area under the curve (AUC). Results: The moisture degree of the lingual mucosa was significantly lower in the dry mouth group (27.2 ± 4.9) than that in the healthy group (29.5 ± 3.1, AUC = 0.653). When a lingual mucosa moisture degree of 31.0 or higher was defined as normal, less than 27.0 as dry mouth, and 27.0 to less than 31.0 as borderline zone of dry mouth, both the sensitivity and the specificity for the diagnosis of dry mouth were close to 80%. Conclusion: These results suggest that the oral moisture-checking device is a usable screening device for dry mouth.

关键词： Dry Mouth Oral Moisture-Checking Device ROC Analysis

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Prostate-specific antigen-based population screening for prostatecancer： current status in Japan and future perspective in Asia

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Asian Journal of Andrology 2015年第3期17卷 475-480页

作者： Yasuhide kitagawa Mikio Namiki Department of Integrative Cancer Therapy and Urology Kanazawa University Graduate School of Medical Science Kanazawa 920-8640 Japan

In Western countries, clinical trials on prostate cancer screening demonstrated a limited benefit for patient survival. In the Asia-Pacific region, including Japan, the rate of prostate-specific antigen （PSA） testing remains very low compared with Western countries, and the benefits of population-based screening remain unclear. This review describes the current status of population screening and diagnosis for prostate cancer in Japan and discusses the efficacy of population screening for the Asian population. Since the 1990s, screening systems have been administered by each municipal government in Japan, and decreases in the prostate cancer mortality rate are expected in some regions where the exposure rate to PSA screening has increased markedly. A population-based screening cohort revealed that the proportion of metastatic disease in cancer detected by screening gradually decreased according to the increased exposure rate, and a decreasing trend in the proportion of cancer with high serum PSA levels after population screening was started. The prognosis of the prostate cancer detected by population screening was demonstrated to be more favorable than those diagnosed outside of the population screening. Recent results in screening cohorts demonstrated the efficacy of PSA. These recent evidences regarding population-based screening in Japan may contribute to establishing the optimal prostate cancer screeninK system in Asian individuals.

关键词： free prostate-specific antigen pro-prostate-specific antigen prostate cancer prostate cancer gene 3 prostate-specificantigen-based population screening serum prostate-specific antigen distribution

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Communication Scheduling with Diversity for Unmanned Aircraft Systems Using Local 5G

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Journal of Communications and Information Networks 2020年第1期5卷 50-61页

作者： Takeru kitagawa Yuichi Kawamoto Nei Kato Graduate School of Information Sciences Tohoku University Aramaki-Aoba 6-3-09Aoba-kuSendai980-8579Japan

The use of unmanned aircraft systems(UAS)for critical public service missions by public organizations,local governments,and social users is *** radio transmission by unmanned aerial vehicles(UAVs)is indispensable in these *** of the standards suitable for UAV wireless communications is local ***,to introduce local 5G into a UAS,several problems specific to UASes must be *** include the deterioration of the signal-to-noise ratio due to topography and obstacles,the uncertainty of the communication environment due to the movement of multiple UAVs,and the limitation of the frequency *** address these problems and to introduce local 5G into the UAS,we propose a novel communication scheduling *** method incorporates transmission modes with *** evaluations shows that total data volumes increase by 1.9~3 times with the proposed scheduling method compared with transmission without diversity or efficient scheduling.

关键词： unmanned aircraft system(UAS) unmanned aerial vehicle(UAV) local 5G diversity scheduling LTE sidelink time division multiple access(TDMA)

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Top-k Outlier Detection from Uncertain Data

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International Journal of Automation and computing 2014年第2期11卷 128-142页

作者： Salman Ahmed Shaikh Hiroyuki kitagawa Graduate School of Systems and Information Engineering University of Tsukuba

Uncertain data are common due to the increasing usage of sensors, radio frequency identification(RFID), GPS and similar devices for data collection. The causes of uncertainty include limitations of measurements, inclusion of noise, inconsistent supply voltage and delay or loss of data in transfer. In order to manage, query or mine such data, data uncertainty needs to be considered. Hence,this paper studies the problem of top-k distance-based outlier detection from uncertain data objects. In this work, an uncertain object is modelled by a probability density function of a Gaussian distribution. The naive approach of distance-based outlier detection makes use of nested loop. This approach is very costly due to the expensive distance function between two uncertain objects. Therefore,a populated-cells list(PC-list) approach of outlier detection is proposed. Using the PC-list, the proposed top-k outlier detection algorithm needs to consider only a fraction of dataset objects and hence quickly identifies candidate objects for top-k outliers. Two approximate top-k outlier detection algorithms are presented to further increase the efficiency of the top-k outlier detection *** extensive empirical study on synthetic and real datasets is also presented to prove the accuracy, efficiency and scalability of the proposed algorithms.

关键词： Top-k distance-based outlier detection uncertain data Gaussian uncertainty cell-based approach PC-list based approach

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Surveillance using trimodal imaging endoscopy after endoscopic submucosal dissection for superficial gastric neoplasia

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World Journal of Gastroenterology 2014年第43期20卷 16311-16317页

作者： Hiroyuki Imaeda Naoki Hosoe Kazuhiro Kashiwagi Yosuke Ida Rieko Nakamura Hidekazu Suzuki yoshimasa Saito Naohisa Yahagi Yasushi Iwao Yuko kitagawa Toshifumi Hibi Haruhiko Ogata Takanori Kanai Department of General Internal Medicine Saitama Medical UniversitySaitama 350-0495Japan Center for Diagnostic and Therapeutic Endoscopy School of MedicineKeio UniversityTokyo 108-8345Japan Division of Gastroenterology Department of Internal MedicineSchool of MedicineKeio UniversityTokyo 108-8345Japan Cancer Center School of MedicineKeio UniversityTokyo 108-8345Japan Center for Preventive Medicine School of MedicineKeio UniversityTokyo 108-8345Japan Department of Surgery School of MedicineKeio UniversityTokyo 108-8345Japan

AIM: To evaluate the effectiveness of trimodal imaging endoscopy (TME) to detect another lesion after endoscopic submucosal dissection (ESD) for superficial gastric neoplasia (SGN).

关键词： Autofluorescence imaging Endoscopic submucosal dissection Superficial gastric neoplasia

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Magneto-Optical Properties of Wider Gap Semiconductors ZnMnTe and ZnMnSe Films Prepared by MBE

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Journal of Electronic Science and Technology 2020年第3期18卷 201-211页

作者： Masaaki Imamura Daisuke Tashima Jiro kitagawa Hironori Asada Department of Electrical Engineering Fukuoka Institute of TechnologyFukuoka 811-0295 Graduate School of Sciences and Technology of Innovation Yamaguchi UniversityUbe 755-8611

TheⅡ-Ⅵbased magnetic semiconductors with a direct and wide optical bandgap are expected to show high potential for optical applications utilizing short wavelength laser diodes(LDs),such as 532-nm green and475-nm blue *** have confirmed that the Faraday rotationθ_F in the ZnMnTe and ZnMnSe films deposited on quartz glass(QG)and sapphire(SA)substrates by using molecular beam epitaxy(MBE)is large near the absorption *** paper reports the magneto-optical properties of ZnMnTe and ZnMnSe films synthesized on the QG and SA substrates,and shows the result of a direct Faraday rotation observation successfully made for the ZnMnTe films under 1.28-kHz alternating magnetic *** optical absorption characteristics of the ZnMnTe films grown on the SA substrates by MBE are discussed by comparing them with the optical absorption properties and photoluminescence spectra of theⅡ-ⅥZnTe parent single crystals.

关键词： Magnetic semiconductors magneto-optical effects wide bandgap ZnMnTe and ZnMnSe films

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Discovery of Zr-based metal-organic polygon:Unveiling new design opportunities in reticular chemistry

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Nano Research 2021年第2期14卷 392-397页

作者： Jiyeon Kim Dongsik Nam Hiroshi kitagawa Dae-Woon Lim Wonyoung Choe Department of Chemistry Ulsan National Institute of Science and Technology50 UNIST-gilUlsan 44919Republic of Korea Department of Chemistry Graduate School of ScienceKyoto UniversityKitashirakawa Oiwake-choSakyo-kuKyoto 606-8502Japan Department of Chemistry and Medical Chemistry College of Science and TechnologyYonsei University1 Yonseidae-gilWonjuGangwon-do 26493Republic of Korea

Metal-based secondary building unit and the shape of organic ligands are the two crucial factors for determining the final topology of metal-organic materials.A careful choice of organic and inorganic structural building units occasionally produces unexpected structures,facilitating deeper fundamental understanding of coordination-driven self-assembly behind metal-organic ***,we have synthesized a triangular metal-organic polygon(MOT-1),assembled from bulky tetramethyl terephthalate and Zr-based secondary building ***,the Zr-based secondary building unit serves as an unusual ditopic Zr-connector,toform metal-organic polygon MOT-1,proven to be a good candidate for water adsorption with *** study highlights the interplay of the geometrically frustrated ligand and secondary building unit in controlling the connectivity of metal-organic *** a strategy can be further used to unveil a new class of metal-organic materials.

关键词： reticular chem istry Zr-based metal-organic polygon geometrical frustration ditopic secondary building unit

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Plant aquaporins:Their roles beyond water transport

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The Crop Journal 2024年第3期12卷 641-655页

作者： Qi Sun Xin Liu Yoshichika kitagawa Giuseppe Calamita Xiaodong Ding Key Laboratory of Agricultural Biological Functional Genes Northeast Agricultural UniversityHarbin 150030HeilongjiangChina Graduate School of Bioresource Sciences Akita Prefectural UniversityAkita 010-0195Japan Department of Biosciences Biotechnologies and BiopharmaceuticsUniversity of Bari‘Aldo Moro’I-70125 BariItaly Key Laboratory of Soybean Biology of Chinese Education Ministry Northeast Agricultural UniversityHarbin 150030HeilongjiangChina

Compared to other organisms,plants have evolved a greater number of aquaporins with diverse substrates and functions to adapt to ever-changing environmental and internal stimuli for growth and *** aquaporins were initially identified as channels that allow water molecules to cross biological membranes,progress has been made in identifying various novel permeable *** studies have characterized the versatile physiological and biophysical functions of plant ***,we review the recent reports that highlight aquaporin-facilitated regulation of major physiological processes and stress tolerance throughout plant life cycles as well as the potential prospects and possibilities of applying aquaporins to improve agricultural productivity,food quality,environmental protection,and ecological conservation.

关键词： Plant aquaporin Substrate Physiological function Agriculture and environment

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