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Analgesic effects of JCM-16021 on neonatal maternal separation-induced visceral pain in rats

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World Journal of Gastroenterology 2010年第7期16卷 837-845页

作者： Joseph JY sung Faculty of Medicine The Chinese University of Hong Kong

AIM:To investigate the pharmacological effect of JCM-16021,a Chinese herbal formula,and its underlying ***:JCM-16021 is composed of seven herbal plant *** raw materials of the formula were examined according to the quality control criteria listed in the Chinese Pharmacopeia(2005).In a neonatal maternal separation(NMS)model,male SpragueDawley rats were submitted to daily maternal separation from postnatal day 2 to day 14,or no specific handling(NH).Starting from postnatal day 60,rats were administered JCM-16021(2,4,8 g/kg per day)orally twice a day for 28 *** threshold pressure and electromyographic activities of external oblique muscles in response to colorectal distention recorded with a Power Lab System(AD Instruments International),were tested as pain *** in serotonin(5-HT)and 5-hydroxyindoleacetic acid(5-HIAA)concentrations in the colon of rats were analyzed;the enterochromaffin cell numbers and serotonin transporter in the colon of rats were also evaluated with an immunohistochemistry ***:NMS treatment significantly reduced pain threshold pressure(37.4±1.4 mmHg),as compared to that of NH rats(57.7±1.9 mmHg,P<0.05).After JCM-16021 treatment,the pain threshold pressure significantly increased when compared to that before treatment(34.2±0.9 mmHg vs 52.8±2.3 mmHg in the high dose group,40.2±1.6 mmHg vs 46.5±1.3 mmHg in the middle dose group,and 39.3±0.7 mmHg vs 46.5±1.6 mmHg in the low dose group,P<0.05).Also JCM-16021 significantly and dose-dependently decreased electromyographic activity to the graded colorectal distension(CRD),(the meanΔAUC values were:0.17±0.03,0.53±0.15,1.06±0.18,1.22±0.24 in the high dose group;0.23±0.04,0.68±0.17,1.27 ±0.26,1.8±0.3 in the middle dose group;and 0.29 ±0.06,0.8±0.16,1.53±0.24,2.1±0.21 in the low dose group for the pressures 20,40,60,80 mmHg),as compared to the NMS vehicle *** meanΔAUC values were:0.57±0.12,1.33±0.18,2.57±0.37,3.08±0.37 for the pressures 20,40,60,80 mmHg(P

关键词： Analgesia effect Neonatal maternal separation Visceral hyperalgesia Herbal medicine Serotonin pathway

UBVVI Surface Photometry of the Spiral Galaxy NGC 300 in the Sculptor Group

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Chinese Journal of Astronomy and Astrophysics 2004年第4期4卷 299-310页

作者： Sang Chul Kim Hwankyung sung Hong Soo Park Eon-Chang sung Korea Astronomy Observatory Taejon 305-348Republic of KoreaDepartment of Astronomy and Space ScienceSejong University98 Gunja-dongGwangjin-guSeoul 143-747Republic of KoreaAstronomy ProgramSEESSeoul National UniversitySeoul 151-742Republic of KoreaKorea Astronomy ObservatoryTaejon 305-348Republic of Korea

We present UBVI surface photometry over a 20.5' × 20.5' area of the late-type spiral galaxy NGC 300. We have derived isophotal maps, surface brightness profiles, ellipticity profiles, position angle profiles, and color profiles. By merging our I-band measurements with those of Boker et al. based on Hubble Space Telescope observations, we have obtained combined I-band surface brightness profiles for the region 0.02' < r < 500' and have decomposed the profiles into three components: a nucleus, a bulge, and an exponential disk.

关键词： galaxies: spiral - galaxies: photometry - galaxies: individual(NGC 300) - galaxies: nuclei

Zero-static-power nonvolatile logic-in-memory circuits for flexible electronics

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Nano Research 2017年第7期10卷 2459-2470页

作者： Byung ChulJang Sang Yoon Yang Hyejeong seong sung Kyu Kim Junhwan Choi sung Gap Im sung-Yool Choi School of Electrical Engineering Graphene/2D Materials Research Center Korea Advanced Institute of Science and Technology (KAIST) Daejeon 34141 Republic of Korea Department of Chemical and Biomolecular Engineering Graphene/2D Materials Research Center Korea Advanced Institute of Science and Technology (KAIST) Daejeon 34141 Republic of Korea Department of Materials Science and Engineering Korea Advanced Institute of Science and Technology (KAIST) Daejeon 34141 Republic of Korea

Flexible logic circuits and memory with ultra-low static power consumption are in great demand for battery-powered flexible electronic systems. Here, we show that a flexible nonvolatile logic-in-memory circuit enabling normally-off computing can be implemented using a poly（1,3,5-trivinyl-l,3,5-trimethyl cyclotrisiloxane）（pV3D3）-based memristor array. Although memristive logic-in-memory circuits have been previously reported, the requirements of additional components and the large variation of memristors have limited demonstrations to simple gates within a few operation cycles on rigid substrates only. Using memristor-aided logic （MAGIC） architecture requiring only memristors and pV3D3-memristor with good uniformity on a flexible substrate, for the first time, we experimentally demonstrated our implementation of MAGIC-NOT and -NOR gates during multiple cycles and even under bent conditions. Other functions, such as OR, AND, NAND, and a half adder, are also realized by combinations of NOT and NOR gates within a crossbar array. This research advances the development of novel computing architecture with zero static power consumption for battery- powered flexible electronic systems.

关键词： memristor memristive logic circuit flexible nonvolatilelogic-in-memory circuit normally-off computing memristor-aided logic(MAGIC) architecture

Fingerprint inspired advanced end-effector and its applications

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Friction 2022年第10期10卷 1739-1750页

作者： sung Ho LEE Hyo sung KIM Han Jun PARK Moon Kyu KWAK Department of Electrical Engineering and Computer Science University of MichiganAnn Arbor 48109USA Department of Mechanical Engineering Kyungpook National UniversityDaegu 41566Republic of Korea

The human fingertip consists of a fingerprint with many micro-grating *** main roles of the fingerprint could be divided into two purposes,namely,the enhancement of the frictional force and the effective transmittance of the *** this study,we present the fingerprint-inspired end-effector that has not only admirable frictional force but also electric *** end-effector is composed of fluorocarbon rubber,one of the famous materials to achieve high frictional force and *** various experiments,the novel performance of micro structured fluorocarbon rubber end-effector(MSFE)is characterized by comparing with a macroscale patterned sample(MPS),which has been already used in real industrial *** results are analyzed ***,as feasible applications,we suggest two applications based on the role of the *** is the conductive astronaut glove with high frictional force,and the other one is a non-slip pad for the next-generation glass transfer *** these experiments,we successfully observe the enhanced system performance and confirm the possibility of using the MSFE as feasible *** believe that the MSFE could be a useful and powerful alternative as an end-effector,not only in the aerospace industry but also in display manufacturing processes.

关键词： fingerprint end-effector fluorocarbon rubber(FKM) glass transfer system spacesuit

Creating Smart House via IoT and Intelligent Computation

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Intelligent Automation & Soft Computing 2023年第1期35卷 415-430页

作者： Wen-Tsai sung sung-Jung Hsiao Department of Electrical Engineering National Chin-Yi University of TechnologyTaichung411030TaiwanChina Department of Information Technology Takming University of Science and TechnologyTaipei City11451TaiwanChina

This study mainly uses the concept of the Internet of Things(IoT)to establish a smart house with an indoor,comfortable,environmental,and real-time monitoring *** the smart house,this investigation employed the temperature-and humidity-sensing module and the lightness module to monitor any con-dition for an intelligent-living *** data of temperature,humidity,and lightness are transmitted wirelessly to the human-machine *** correlation of the weight of the extension theory is used to analyze the ideal and comfortable environment so that people in the indoor environment can feel better thermal comfort and *** this study,improved particle swarm optimization(IPSO)is employed—an effective evolutionary method used to search the function *** is simple and has a fast *** convergence accuracy of this algorithm is not high at the beginning,and it can easily fall into the local extreme *** effect of the inertia weight in mix extension theory and PSO becomes IPSO-Extension Neural Network(ENN),which was analyzed and found *** by the idea of power function,a new non-linear strategy for decreasing inertia weight(DIW)was proposed based on the existing linear ***,a novel hierarchical multi-sensor data fusion algorithm adopting this strategy was presented,and the weight factor of the data fusion was *** distinctive feature of this algorithm is its capability of fusing data in a near-optimal manner when there is no available information about the reliability of the information sources,the degree of redundancy/complementarities of the information sources,and the structure of the *** obtained effective information from the fusion data,successfully removed the noise disturbance,and achieved favorable results.

关键词： IoT data fusion extension theory particle swarm optimization decreasing inertia weight IPSO-ENN

Intelligent Home Using Fuzzy Control Based on AIoT

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Computer Systems Science & Engineering 2023年第5期45卷 1063-1081页

作者： sung-Jung Hsiao Wen-Tsai sung Department of Information Technology Takming University of Science and TechnologyTaipei City11451Taiwan China Department of Electrical Engineering National Chin-Yi University of TechnologyTaichung411030Taiwan China

The Internet of Things has grown rapidly in recent years,and the technologies related to it have been widely used in various *** idea of this paper is to build a set of Internet of Things systems in a smart home wireless network environment,with the purpose of providing people with a more comfortable,convenient,and safe *** the sensing layer of the Internet of Things,we discuss the uses of common sensing technologies on the Internet and combine these with Arduino microprocessors to integrate temperature sensing modules,humidity sensing modules,gas sensing modules,and particulate matter 2.5(PM2.5)sensing *** the network layer,we discuss using the Wi-Fi wireless networking function composed of a home router and a wireless Wi-Fi chip Espressif system 8266(ESP8266)to transmit the collected home-sensing data to the ThingSpeak cloud ***,in the application layer part,the system uses a mobile device with fuzzy calculation optimization *** system is also connected remotely for home environment monitoring,so the home environment can be optimized anytime,anywhere.

关键词： Wireless sensor networks internet of things ESP8266 thingspeak fuzzy control

Dynamic modeling and analysis of vortex filament motion using a novel curve-fitting method

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Chinese Journal of Aeronautics 2016年第1期29卷 53-65页

作者： Chang-Joo Kim Soo Hyung Park Sang Kyung sung sung-Nam Jung Department of Aerospace Information Engineering Konkuk UniversitySeoul 05029Republic of Korea

Applications of a novel curve-fitting technique are presented to efficiently predict the motion of the vortex filament, which is trailed from a rigid body such as wings and rotors. The gov- erning equations of the motion, when a Lagrangian approach with the present curve-fitting method is applied, can be transformed into an easily solvable form of the system of nonlinear ordinary dif- ferential equations. The applicability of Bezier curves, B-spline, and Lagrange interpolating polyno- mials is investigated. Local Lagrange interpolating polynomials with a shift operator are proposed as the best selection for applications, since it provides superior system characteristics with minimum computing time, compared to other methods. In addition, the Gauss quadrature formula with local refinement strategy has been developed for an accurate prediction of the induced velocity computed with the line integration of the Biot-Savart law. Rotary-wing problems including a vortex ring problem are analyzed to show the efficiency, accuracy, and flexibility in the applications of the pro- posed method.

关键词： Aerodynamics Biot-Savart law Curve-fitting method Free-vortex wake Rotary wing Vortex filament

Assessment of the clear-sky bias issue using continuous PM10 data from two AERONET sites in Korea

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Journal of Environmental Sciences 2017年第3期29卷 151-160页

作者： Yongjoo Choi Young sung Ghim Department of Environmental Science Hankuk University of Foreign StudiesYongin 449-791Korea

A bias in clear-sky conditions that will be involved in estimating particulate matter （PM） concentration from aerosol optical depth （AOD） was examined using PM10 from two Aerosol Robotic Network sites in Korea. The study periods were between 2004 and 2007 at Anmyon and between 2003 and 2011 at Gosan, when both PM10 and AOD were available. Mean PM10 when AOD was available （PMAOD） was higher than that from all PM10 data （PMall） by 5.1 and 9.9 μg/m3 at Anmyon and Gosan, which accounted for 11% and 26% of PMall, respectively. Because of a difference between mean PM10 under daytime clear-sky conditions （PMclear） and PMAoD, the variations in APM10, the difference of PMan from PMdear rather than from PMAoD, were investigated. Although monthly variations in APMlo at the two sites were different, they were positively correlated to those in AT, similarly defined as APM10 except for temperature, at both sites. APM10 at Anmyon decreased to a negative value in January due to an influence of the Siberian continental high-pressure system while APM10 at Gosan was high in winter due to an effect of photochemical production at higher temperatures than at Anmyon.

关键词： AERONETData recovery rateCloud amountWind speedPhotochemical productionSiberian high

SYNTHESIS AND CHARACTERIZATION OF HYDROPHOBIC-HYDROPHILIC MULTIBLOCK COPOLYMERS FOR BIOMEDICAL APPLICATIONS

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Chinese Journal of Polymer Science 1999年第2期17卷 113-122页

作者： Yong Kiel sung Yong Joo Kim sung Wan Kim Department of Chemistry College of Natural Science Dongguk University 3Ga 26 PhildongJunggu Seoul 100-715 KoreaReliability Technology Division NITQ 2 Chungangdong Kwachoncity Kyunggido 427-010 KoreaCenter for Controlled Chemical Delivery University of Utah Salt Lake City Utah 84112 U. S. A.

The synthesis and characterization of amphiphilic copolymers of poly（dimethyl siloxane）(PDMS),poly（ethylene oxide）(PEO), and heparin（Hep） were investigated. These multiblock copolymers wereidentified using;H-NMR, FTIR, end group analysis, and sulfur elemental analysis. The multiblockcopolymers were characterized by using DSC and X-ray diffractometry. The glass transition temperature,crystalline melting characteristics, annealing effect, and cold crystallization of the block copolymers weredetermined by DSC. The crystallinity of the block copolymers was also determined by X-ray diffractionmethod.

关键词： Heparinized block copolymer Biomedical polymer Synthesis Characterization