检索结果-南通市图书馆

Journal of Systems Science and Systems Engineering 2024年第1期33卷 52-76页

作者： Shimin Sun yongheng wang Yawen wang Mengyu Mao School of Business Administration Northeastern UniversityShenyang110169China

CEO compensation stickiness represents an important indicator to measure the effectiveness of compensation *** study uses CEO career experience data and compensation stickiness data from Shanghai and Shenzhen A-share listed companies from 2015 to 2020 to investigate the compensation contracts’effectiveness of CEOs with diverse career *** findings are as follows:1)Compensation stickiness is more pronounced for CEOs with diverse career *** to the mechanism test,these CEOs with diverse career experiences can obtain compensation incentives by reducing corporate uncertainty perception and improving total factor *** approach leads to increased compensation stickiness and the effectiveness of compensation *** with diverse career experiences may receive excess compensation by raising agency costs,which intensifies compensation stickiness and weakens the effectiveness of compensation contracts.2)Compensation stickiness of CEOs with diverse career experiences is more significant in companies with lower investor protection,which brings about less effective compensation *** contrast,in companies with higher diversification,the compensation stickiness of CEOs with diverse career experiences is more significant,which delivers more effective compensation *** conclusions deepen the research of CEO compensation contracts and provide a helpful reference for CEO compensation management practices.

关键词： CEOs’diverse career experiences effectiveness of compensation contracts compensation stickiness agency problems incentive mechanisms

SiO_(2) Induces Iron Overload and Ferroptosis in Cardiomyocytes in a Silicosis Mouse Model

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Biomedical and Environmental Sciences 2024年第6期37卷 617-627页

作者： yongheng wang Ning Li Yi Guan Tong LI Yuxiu Zhang Hong Cao Zhihua Yu Zhiheng Li Shuoyan Li Jiahao Hu Wenxin Zhou Sisi Qin Shuang Li Sanqiao Yao School of Public Health North China University of Science and TechnologyTangshan 063210HebeiChina Hebei Key Laboratory of Occupational Health and Safety for Coal Industry North China University of Science and TechnologyTangshan 063210HebeiChina Occupational Disease Prevention and Control Institute of Jinneng Holding Coal Industry Group Co. LtdDatong 037001ShanxiChina China Pingmei Shenma Group Occupational Disease Prevention and Control Hospital Pingdingshan 467000HenanChina School of Public Health Xinxiang Medical UniversityXinxiang 453003HenanChina

Objective The aim of this study was to explore the role and mechanism of ferroptosis in SiO_(2)-induced cardiac injury using a mouse *** Male C57BL/6 mice were intratracheally instilled with SiO_(2) to create a silicosis ***-1(Fer-1)and deferoxamine(DFO)were used to suppress *** biomarkers,oxidative stress markers,histopathology,iron content,and the expression of ferroptosis-related proteins were *** SiO_(2) altered serum cardiac injury biomarkers,oxidative stress,iron accumulation,and ferroptosis markers in myocardial ***-1 and DFO reduced lipid peroxidation and iron overload,and alleviated SiO_(2)-induced mitochondrial damage and myocardial ***_(2) inhibited Nuclear factor erythroid 2-related factor 2(Nrf2)and its downstream antioxidant genes,while Fer-1 more potently reactivated Nrf2 compared to *** Iron overload-induced ferroptosis contributes to SiO_(2)-induced cardiac *** ferroptosis by reducing iron accumulation or inhibiting lipid peroxidation protects against SiO_(2) cardiotoxicity,potentially via modulation of the Nrf2 pathway.

关键词： SiO_(2) exposure Iron overload Ferroptosis Cardiac injury Nrf2

计及碳排放流的光储充一体化电站及加氢站协同规划

在线全文

学校读者我要写书评

暂无评论

电力系统自动化 2024年第13期48卷 40-49页

作者：陈威王永恒沈欣炜杜云飞清华大学深圳国际研究生院海洋工程研究院广东省深圳市518055

随着“双碳”目标的深入推进,新能源汽车的发展成为解决交通-能源领域碳排放问题的重要途径。文中提出一种计及碳排放流的光储充一体化电站和汽车加氢站的联合规划方法。首先,采用蒙特卡洛方法对新能源汽车的时空特性进行随机抽样,考虑... 详细信息

随着“双碳”目标的深入推进,新能源汽车的发展成为解决交通-能源领域碳排放问题的重要途径。文中提出一种计及碳排放流的光储充一体化电站和汽车加氢站的联合规划方法。首先,采用蒙特卡洛方法对新能源汽车的时空特性进行随机抽样,考虑充能站位置、规模和能源供应等因素,以系统经济性最优为目标建立规划模型。然后,引入碳排放流理论,结合潮流计算及电力网络分析方法,将碳排放成本纳入目标函数。最后,以中国南方地区某城市片区主动配电网为例,对不同光伏出力、新能源汽车渗透率场景的规划结果进行分析,验证了所提方法的有效性。

关键词：配电网光储充一体化电站加氢站碳排放流协同规划

同方期刊数据库

在线全文

学校读者我要写书评

暂无评论

冷轧厂薄带钢高效生产的问题及解决方案分析

山西冶金 2024年第1期47卷 237-238,241页

作者：王永恒河钢邯钢公司邯宝冷轧厂河北邯郸056000

热镀锌板具有抗腐蚀强、易于深加工、使用寿命长、成本低以及表面美观等特点,主要用于家用电器、汽车等产品的内部构件和面板应用。随着家电板、汽车板工业的发展,家电和汽车所用的镀锌板占全国钢产量的比例逐步提升。随着国内外家电板... 详细信息

热镀锌板具有抗腐蚀强、易于深加工、使用寿命长、成本低以及表面美观等特点,主要用于家用电器、汽车等产品的内部构件和面板应用。随着家电板、汽车板工业的发展,家电和汽车所用的镀锌板占全国钢产量的比例逐步提升。随着国内外家电板、汽车板轻质化和高质量的要求,客户对产品表面质量要求越来越严格。针对生产线在提速增产过程中出现的入口跑偏、工艺段带钢表面质量缺陷和薄带钢薄锌层产速受限问题,提出了相应的改进措施。优化后,不仅提高了产量,而且提高了产品质量。

关键词：热镀锌板冷轧厂薄带钢跑偏工艺段表面质量缺陷

Fluid-structure interaction simulation of pathological mitral valve dynamics in a coupled mitral valve-left ventricle model

在线全文

学校读者我要写书评

暂无评论

智慧医学(英文) 2023年第2期3卷 104-114页

作者： Li Cai Tong Zhao yongheng wang Xiaoyu Luo Hao Gao NPU-UoG International Cooperative Lab for Computation and Application in Cardiology School of Mathematics and StatisticsNorthwestern Polytechnical UniversityXi’anShaanxi 710129China Xi’an Key Laboratory of Scientific Computation and Applied Statistics Xi’anShaanxi 710129China School of Mathematics and Statistics University of GlasgowGlasgowG128QQUnited Kingdom

Background Understanding the interaction between the mitral valve(MV)and the left ventricle(LV)is very important in assessing cardiac pump function,especially when the MV is *** dysfunction is a major medical problem owing to the essential role of the MV in cardiac pump *** modelling can provide new approaches to gain insight into the functions of the MV and *** In this study,a previously developed LV-MV model was used to study cardiac dynamics of MV leaflets under normal and pathological conditions,including hypertrophic cardiomyopathy(HOCM)and calcification of the *** coupled LV-MV model was implemented using a hybrid immersed boundary/finite element method to enable assessment of MV haemodynamic *** parameters of the HOCM and calcified valves were inversely determined from published experimental *** LV compensation mechanism was further studied in the case of the calcified *** Our results showed that MV dynamics and LV pump function could be greatly affected by MV *** example,the HOCM case showed bulged MV leaflets at the systole owing to low stiffness,and the calcified MV was associated with impaired diastolic filling and much-reduced stroke *** further demonstrated that either increasing the LV filling pressure or increasing myocardial contractility could enable a calcified valve to achieve near-normal pump *** The modelling approach developed in this study may deepen our understanding of the interactions between the MV and the LV and help in risk stratification of heart valve disease and in silico treatment planning by exploring intrinsic compensation mechanisms.

关键词： Mitral valve Left ventricle Valve disease Hybrid immersed boundary/finite element method Calcification Hypertrophic cardiomyopathy

健脾益肾方联合左甲状腺素钠片治疗分化型甲状腺癌术后临床观察

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中医药临床杂志 2024年第7期36卷 1382-1386页

作者：董宇轩王永恒段姗姗湖南中医药大学第一中医临床学院湖南长沙410007 湖南中医药大学第一附属医院湖南长沙410007

目的:探讨分化型甲状腺癌(DTC)术后采用健脾益肾方联合左甲状腺素钠片治疗的临床效果。方法:依据随机数字表法将医院2021年10月-2023年10月152例完成甲状腺切除术治疗的DTC患者分为对照组(n=76,术后常规治疗+左甲状腺素钠片)和观察组(n=... 详细信息

目的:探讨分化型甲状腺癌(DTC)术后采用健脾益肾方联合左甲状腺素钠片治疗的临床效果。方法:依据随机数字表法将医院2021年10月-2023年10月152例完成甲状腺切除术治疗的DTC患者分为对照组(n=76,术后常规治疗+左甲状腺素钠片)和观察组(n=76,术后常规治疗+左甲状腺素钠片+健脾益肾方),两组均持续治疗3个月。比较两组中医证候评分、炎症反应、免疫功能及不良反应情况。结果:治疗3个月,观察组中医证候评分、炎症反应指标均较低于对照组,免疫功能指标改善优于对照组(P0.05)。结论:DTC术后采用健脾益肾方联合左甲状腺素钠片治疗可有效减轻临床症状,降低炎症反应,改善免疫功能,且未明显增加不良反应。

关键词：分化型甲状腺癌左甲状腺素钠片健脾益肾方炎症反应免疫功能

数字减影血管造影引导下经侧孔快速交换法与传统鼻胃管减压治疗粘连性肠梗阻的疗效观察

在线全文

学校读者我要写书评

暂无评论

临床外科杂志 2024年第3期32卷 289-292页

作者：廖甜王永恒李澜黄湘俊湖南中医药大学第一附属医院胃肠甲状腺血管外科长沙410007

目的观察数字减影血管造影技术(DSA)引导下经侧孔快速交换法与传统鼻胃管减压治疗粘连性肠梗阻的临床疗效。方法 2019年1月~2021年1月本院收治的粘连性肠梗阻病人84例,按随机数字表法将病人分为研究组(42例)和对照组(42例),对照组予以... 详细信息

目的观察数字减影血管造影技术(DSA)引导下经侧孔快速交换法与传统鼻胃管减压治疗粘连性肠梗阻的临床疗效。方法 2019年1月~2021年1月本院收治的粘连性肠梗阻病人84例,按随机数字表法将病人分为研究组(42例)和对照组(42例),对照组予以传统鼻胃管减压治疗,研究组予以DSA引导下经侧孔快速交换法置管减压治疗。比较两组临床疗效、恢复指标(排气时间、拔管时间、进食时间、首次排便时间、腹痛缓解时间、X线气液平面消失时间、平均住院时间)、疼痛程度(VAS评分)、生活质量(SF-36评分)的差异。结果等级资料秩和检验显示,两组临床疗效比较差异有统计学意义(P<0.05),研究组总有效率(92.86%)高于对照组(71.43%),差异有统计学意义(P<0.05)。研究组排气时间、拔管时间、进食时间、首次排便时间、腹痛缓解时间、X线气液平面消失时间、平均住院时间分别为(78.61±20.38)小时、(80.35±20.26)小时、(82.49±21.59)小时、(88.66±23.55)小时、(3.49±0.75)天、(4.31±1.16)天和(6.53±1.1)天,对照组分别为(101.36±31.56)小时、(104.33±28.85)小时、(108.41±25.55)小时、(141.32±35.49)小时、(6.05±1.29)天、(7.29±1.32)天和(10.01±2.06)天,两组比较,差异有统计学意义(P<0.05)。重复测量方差分析结示,两组治疗后1天、治疗后3天VAS评分与治疗前比较,明显降低,且治疗后3天的VAS评分低于治疗后1天,但研究组治疗后1天、治疗后3天的VAS评分均低于对照组,差异有统计学意义(P<0.05)。两组出院时SF-36量表各因子得分与治疗前比较均升高,且研究组出院时SF-36量表各因子得分均高于对照组,差异有统计学意义(P<0.05)。结论 DSA引导下经侧孔快速交换法置管减压治疗粘连性肠梗阻可有效缓解病人疼痛程度,促进早期恢复,提高生活质量。

关键词：粘连性肠梗阻数字减影血管造影技术经侧孔快速交换法传统鼻胃管减压疗效

基于5G NR-U的分布式新能源采集调控策略

在线全文

学校读者我要写书评

暂无评论

电力信息与通信技术 2024年第4期22卷 86-91页

作者：王永恒何玮珊李静静景春峰国网新疆电力有限公司巴州供电公司新疆维吾尔自治区巴音郭楞蒙古自治州841000 南京南瑞信息通信科技有限公司江苏省南京市210003

随着电力市场的不断发展,电力终端接入规模不断扩大,分布式新能源采集调控策略成为重要的研究热点。通过使用工作于免许可频段的5G空中接口(5G new radio in unlicensed spectrum,5G NR-U)技术可以建立安全、低成本、自主可控的电力无... 详细信息

随着电力市场的不断发展,电力终端接入规模不断扩大,分布式新能源采集调控策略成为重要的研究热点。通过使用工作于免许可频段的5G空中接口(5G new radio in unlicensed spectrum,5G NR-U)技术可以建立安全、低成本、自主可控的电力无线专网,为实现智能电网中分布式新能源采集调控业务应用提供安全、高速、灵活的平台。文章提出一种基于5G NR-U电力专网的分布式新能源采集调控策略,研究微电网群中的分布式光伏发电新能源信息共享与资源调控,并使用Stackelberg博弈算法求解最优调控策略。仿真结果表明,该调控策略能够显著提高微电网群的消纳能力,提高微电网运行稳定性和安全性。

关键词：新能源采集调控微电网群分布式光伏发电 5G NR-U Stackelberg博弈

3D打印技术用于经鼻蝶窦入路垂体腺瘤切除术应用效果及对血清MMP-9和IGF-1水平的影响

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

中国医学装备 2024年第4期21卷 112-116页

作者：韩莹陈兴河王永恒赵锦程吴磊秦皇岛市第一医院神经外科秦皇岛066000

目的:探究3D打印技术在经鼻蝶窦入路垂体腺瘤(PA)切除术的应用效果及对血清基质金属蛋白酶-9(MMP-9)和胰岛素样生长因子-1(IGF-1)水平的影响。方法:选取2020年5月至2022年5月秦皇岛市第一医院收治的84例PA患者,按照随机数表法将其分为... 详细信息

目的:探究3D打印技术在经鼻蝶窦入路垂体腺瘤(PA)切除术的应用效果及对血清基质金属蛋白酶-9(MMP-9)和胰岛素样生长因子-1(IGF-1)水平的影响。方法:选取2020年5月至2022年5月秦皇岛市第一医院收治的84例PA患者,按照随机数表法将其分为观察组和对照组,每组42例。对照组行经鼻蝶窦入路垂体腺瘤切除术,观察组行经鼻蝶窦入路垂体腺瘤切除术联合应用3D打印技术,比较两组肿瘤切除效果、围术期指标、视力改善情况、MMP-9和IGF-1水平,以及鼻腔功能的鼻气道阻力(NAR)、T&T嗅觉测试评分及并发症。结果:观察组肿瘤切除效果优于对照组,差异有统计学意义(U=2.286,P0.05)。结论:3D打印技术用于经鼻蝶窦入路垂体腺瘤切除术可提高肿瘤切除效果,优化手术操作,减少创伤,有利于减轻疼痛,改善嗅觉功能与视力视野,并能降低血清MMP-9、IGF-1水平,且安全性较高。

关键词：垂体腺瘤经鼻蝶窦入路垂体腺瘤(PA)切除术 3D打印技术基质金属蛋白酶-9(MMP-9) 胰岛素样生长因子-1(IGF-1)

In utero delivery of mRNA to the heart,diaphragm and muscle with lipid nanoparticles

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

Bioactive Materials 2023年第7期25卷 387-398页

作者： Kewa Gao Jie Li Hengyue Song Hesong Han yongheng wang Boyan Yin Diana L.Farmer Niren Murthy Aijun wang Department of Surgery School of MedicineUniversity of CaliforniaDavisSacramentoCA95817United States Department of Bioengineering University of CaliforniaBerkeleyCA94704United States Institute for Pediatric Regenerative Medicine Shriners Hospitals for ChildrenSacramentoCA95817United States Department of Biomedical Engineering University of CaliforniaDavisCA95616United States Department of Burns and Plastic Surgery The Third Xiangya Hospital of Central South UniversityHunan410013China

Nanoparticle-based drug delivery systems have the potential to revolutionize medicine,but their low vascular permeability and rapid clearance by phagocytic cells have limited their medical *** delivered at the in utero stage can overcome these key limitations due to the high rate of angiogenesis and cell division in fetal tissue and the under-developed immune ***,very little is known about nanoparticle drug delivery at the fetal stage of *** this report,using Ai9 CRE reporter mice,we demonstrate that lipid nanoparticle(LNP)mRNA complexes can deliver mRNA in utero,and can access and transfect major organs,such as the heart,the liver,kidneys,lungs and the gastrointestinal tract with remarkable efficiency and low *** addition,at 4 weeks after birth,we demonstrate that 50.99±5.05%,36.62±3.42%and 23.7±3.21%of myofiber in the diaphragm,heart and skeletal muscle,respectively,were ***,we show here that Cas9 mRNA and sgRNA complexed to LNPs were able to edit the fetal organs in *** experiments demonstrate the possibility of non-viral delivery of mRNA to organs outside of the liver in utero,which provides a promising strategy for treating a wide variety of devastating diseases before birth.

关键词： In utero mRNA delivery Nanoparticles Gene editing CRISPR/Cas9