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Case Reports in Clinical Medicine 2020年第9期9卷 275-281页

作者： Jiaqi Xu Yujie Cui Xinfeng Huang yongbo meng Jian Xin Yong Cheng Burn and Plastic Surgery The Fifth Affiliated Hospital Sun Yat-sen University Zhuhai China Rheumatology The Fifth Affiliated Hospital Sun Yat-sen University Zhuhai China

Neuroendocrine tumors (NETs) are often misdiagnosed because they can involve any part of the body and have non-specific symptoms. Here, we report a case of a 39-year-old man with rectal neuroendocrine tumor (RNET) and hepatic metastases treated with a combination of radical surgery and Everolimus therapy. The patient complained of abdominal distension, pain, and constipation of one month duration. Enhanced CT scan of the abdomen, colonoscopy and Biopsy findings confirmed the diagnosis of rectal neuroendocrine tumor. As the anatomical structures were clear and the masses seemed to be resectable, we decided to initiate treatment with radical operation and Everolimus therapy. The patient has responded well to the treatment with no evidence of recurrence after 4 years of follow-up. This case is interesting because of the rarity of this neoplasm and its initial misdiagnosis as a giant hepatic carcinoma (hepatoma). It also demonstrates that a combination of curative surgical resection and Everolimus is a good option in a patient with large colorectal neuroendocrine tumors and massive hepatic metastases.

关键词： Rectal Neuroendocrine Tumor Liver Metastases Everolimus Radical Operation

Overoxidized poly(3,4-ethylenedioxythiophene)-overoxidized polypyrrole composite films with enhanced electrocatalytic ability for rutin and luteolin determination

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Frontiers of Chemical Science and Engineering 2023年第6期17卷 735-748页

作者： Rongqian meng Jianke Tang Hong Yang Lijun Guo yongbo Song Qiaoling Li Yulan Niu Department of Chemistry and Chemical Engineering Taiyuan Institute of TechnologyTaiyuan 030008China School of Chemical Engineering and Technology North University of ChinaTaiyuan 030051China School of Science North University of ChinaTaiyuan 030051China

In this study, a simple and effective method was proposed to improve the electrocatalytic ability of overoxidized poly(3,4-ethylenedioxythiophene)-overoxidized polypyrrole composite films modified on glassy carbon electrode for rutin and luteolin determination. The composite electrode was prepared by cyclic voltammetry copolymerization with LiClO_(4)-water as the supporting electrolyte. The peak current of rutin and luteolin on the composite electrode gradually decreased or even disappeared with the increase in the positive potential limit. After incubation in NaOH–ethanol solution with a volume ratio of 1:1, the composite electrodes prepared at positive potential limit greater than 1.5 V exhibited enhanced differential pulse voltammetry peak currents, reduced charge transfer resistance, larger effective specific surface area and higher electron transfer rate constant. The composite electrode prepared in the potential range of 0–1.7 V showed optimal electrocatalytic performance. The X-ray photoelectron spectroscopy results indicated that the content of –SO_(2)/–SO and –C=N– groups in the composite film increased significantly after incubation. Further, the Raman spectra and Fourier transform infrared spectra revealed that the thiophene ring structure changed from benzene-type to quinone-type, and the quinone-type pyrrole ring was formed. The electrocatalytic mechanism of the composite film was proposed based on the experimental results and further verified by Density Functional Theory calculation.

关键词： overoxidized poly(3,4-ethylenedioxythiophene)-overoxidized polypyrrole rutin luteolin incubation electrocatalytic mechanism

Selenium Regulates Antioxidant Capacities and Diterpenoid Biosynthesis in the Medicinal Plant Isodon rubescens

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Phyton-International Journal of Experimental Botany 2024年第7期93卷 1705-1716页

作者： Fenglan Zhao Shuwen Wu Xue meng Jianping Xue yongbo Duan Anhui Provincial Engineering Laboratory for Efficient Utilization of Featured Resource Plants College of Life SciencesHuaibei Normal UniversityHuaibei235000China Huaibei Key Laboratory of Efficient Cultivation and Utilization of Resource Plants College of Life SciencesHuaibei Normal UniversityHuaibei235000China

Dōng líng căo,the dried aboveground parts of Isodon rubescens(Hemls.)Hara.,is commonly consumed as a med-icinal decoction or tea *** beverages can be an important source of human dietary selenium(Se).However,how *** plants respond to exogenous Se remains *** this study,a pot cultivation experiment was employed to investigate the phenotypic and physiological responses of *** plants exposed to *** days after applying different concentrations of sodium selenate to the soil,the Se enrichment capa-city,growth indices,antioxidant capacities,and the content ofﬂavonoids and diterpenoids were measured in the ***,the oridonin content was quantiﬁed using the high-performance liquid chromatography method,and the expression levels of key diterpenoid synthesis genes were analyzed by quantitative real-time PCR(qRT-PCR).*** plants efﬁciently accumulated Se,with the Se content increasing proportionally to the applied dose,reaching levels of nearly 200 mg·kg^(-1) dry leaves as Se concentration *** of the three Se treat-ments signiﬁcantly altered the phenotypic indices,except a longer root length occurred in the 3μM·kg^(-1) Se *** three Se doses,6μM·kg^(-1) Se gave the highest accumulation ofﬂavonoids,diterpenoids,and oridonin,with the increase of 2.0-,1.8-,and 1.9-fold in aboveground parts,*** application boosted the activities of antioxidant enzymes and antioxidant capacities according to 2,2-Diphenyl-1-picrylhydrazyl(DPPH),ferric reducing/antioxidant power,and tea brewing color *** key synthase genes were upregulated signiﬁcantly by 6μM·kg^(-1) Se treatment,notably 1-deoxy-D-xylulose 5-phosphate reductoisomerase(IrDXR),with a 5-fold increase,and kaurene synthase-like 4(IrKSL4),with a 6-fold ***,Se application in *** cultivation may be a potential biofortiﬁcation method to supplement Se while increasingﬂavonoid and diterpenoid contents.

关键词： Flavonoids oridonin physiological indicators quantitative real-time PCR selenium

Deformation Localization and Shear Fracture of a Rapidly Solidified Al-Fe-V-Si Alloy at Elevated Temperature

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Journal of Materials Science & Technology 2007年第2期23卷 237-241页

作者： yongbo XU Shenyang National Laboratory for Materials Sciences Institute of Metal Research Chinese Academy of SciencesShenyang 110016 China

The tensile and fatigue behavior of a dispersoid strengthened, powder metallurgy Al-Fe-V-Si alloy at ambient and elevated temperatures was investigated. The results show that the strength and ductility of the alloy decrease significantly with increasing temperature and decreasing strain rate. Micro-structural examinations reveal that this change in mechanical behavior with increasing temperature is related to the mode of deformation of the alloy. Further observations show that localized shear deformation is responsible for the losses in both strength and ductility of the alloy at elevated temperature.

关键词： Al-Fe-V-Si alloy Dispersoids Localized shear deformation Shear fracture Dislocations

Electromagnetohydrodynamic flows and mass transport in curved rectangular microchannels

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Applied Mathematics and Mechanics(English Edition) 2020年第9期41卷 1431-1446页

作者： yongbo LIU Yongjun JIAN School of Mathematical Science Inner Mongolia UniversityHohhot 010021China

Curved microchannels are often encountered in lab-on-chip systems because the effective axial channel lengths of such channels are often larger than those of straight microchannels for a given per unit chip *** this paper,the effective diffusivity of a neutral solute in an oscillating electromagnetohydrodynamic(EMHD)flow through a curved rectangular microchannel is investigated *** flow is assumed as a creeping flow due to the extremely low Reynolds number in such microflow *** the theoretical analysis,we find that the effective diffusivity primarily depends on five dimensionless parameters,i.e.,the curvature ratio of the curved channel,the Schmidt number,the tidal displacement,the angular Reynolds number,and the dimensionless electric field strength *** on the obtained results,we can precisely control the mass transfer characteristics of the EMHD flow in a curved rectangular microchannel by appropriately altering the corresponding parameter values.

关键词： electromagnetohydrodynamic(EMHD)flow curved rectangular microchannel mass transfer characteristic effective diffusivity

UAV-based spatial pattern of three-dimensional green volume and its influencing factors in Lingang New City in Shanghai,China

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Frontiers of Earth Science 2021年第3期15卷 543-552页

作者： Sijun ZHENG Chen meng Jianhui XUE yongbo WU Jing LIANG Liang XIN Lang ZHANG College of Biology and the Environment Nanjing Forestry UniversityNanjing 210037China Shanghai Academy of Landscape Architecture Science and Planning Shanghai 200241China School of Ecological and Environmental Sciences East China Normal UniversityShanghai 200241China Shanghai Key Laboratory for Urban Ecological Processes and Eco-Restoration Shanghai 200241China Shanghai Institute of Surveying and Mapping Shanghai 200063China

Three-dimensional green volume(TDGV)reflects the quality and quantity of urban green space and its provision of ecosystem services;therefore,its spatial pattern and the underlying influential factors play important roles in urban planning and ***,little is known about the factors contributing to the spatial pattern of *** this paper,TDGV and land use intensity(LUI)extracted from high spatial resolution(0.05 m)remotely sensed data acquired by an unmanned aerial vehicle(UAV),anthropogenic factors^(1))and natural factors^(2))were utilized to identify the spatial pattern of TDGV and the potential influencing factors in Lingang New City,a rapidly developed coastal town in *** results showed that most of the TDGV was distributed in the western part of this new city and that its spatial variations were significantly *** corresponded well with the chronologies of land formation,urban planning,and construction in the *** least squares(GLS)analysis of TDGV(grid cell size:100×100 m)and its influencing factors showed that the TDGV in this new city was significantly negatively correlated with both LUI and distance from roads and significantly positively correlated with land formation time and distance from *** from buildings did not affect ***,the degree of influence decreased in the following order:distance from water>land formation time>distance from roads>*** results indicate that the spatial pattern of TDGV in this new town was mainly affected by natural factors(i.e.,the distance from water and land formation time)and that the artificial disturbances caused by rapid urbanization did not decrease the regional *** main factors shaping the spatial distribution of TDGV in this city were local natural *** findings suggest that the improvement in local soil and water conditions should be emphasized in the construction of new cities in coastal areas to ensure the efficient provision of ecolo

关键词： low-altitude remote sensing LUI urban space layout land formation time dominant factor

Rotating electroosmotic flows in soft parallel plate microchannels

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Applied Mathematics and Mechanics(English Edition) 2019年第7期40卷 1017-1028页

作者： yongbo LIU Yongjun JIAN School of Mathematical Science Inner Mongolia University

We present a theoretical investigation of rotating electroosmotic flows(EOFs) in soft parallel plate microchannels. The soft microchannel, also called as the polyelectrolyte-grafted microchannel, is denoted as a rigid microchannel coated with a polyelectrolyte layer(PEL) on its surface. We compare the velocity in a soft microchannel with that in a rigid one for different rotating frequencies and find that the PEL has a trend to lower the velocities in both directions for a larger equivalent electrical double layer(EDL) thickness λFCL(λFCL = 0.3) and a smaller rotating frequency ω(ω < 5).However, for a larger rotating frequency ω(ω = 5), the main stream velocity u far away from the channel walls in a soft microchannel exceeds that in a rigid one. Inspired by the above results, we can control the EOF velocity in micro rotating systems by imparting PELs on the microchannel walls, which may be an interesting application in biomedical separation and chemical reaction.

关键词： rotating electroosmotic flow (EOF) soft microchannel polyelectrolyte layer (PEL) thickness

Electroviscous effect on electromagnetohydrodynamic flows of Maxwell fluids in parallel plate microchannels

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Applied Mathematics and Mechanics(English Edition) 2019年第10期40卷 1457-1470页

作者： yongbo LIU Yongjun JIAN School of Mathematical Science Inner Mongolia University

Considering the influence of the streaming potential and electroviscous effects, the analytical solutions for electromagnetohydrodynamic (EMHD) flows in parallel plate microchannels are obtained. The electrolyte solutions in the microchannels are taken as generalized Maxwell fluids, and slip boundary conditions are adopted. To accurately analyze the EMHD flow characteristics, the variation trends of the electroviscous effects with the corresponding parameters must be understood. The results show that the electroviscous effects increase with the increase in the relaxation time De, the slip coefficient , and the wall zeta potential 0. However, the increase in the inverse of the electrical double-layer (EDL) thickness K, the electrical oscillating Reynolds number Re, and the ionic P'eclet number Pe can decrease the electroviscous effects. We also demonstrate that the electroviscous effect on the EMHD flows of generalized Maxwell fluids is larger than that of Newtonian fluids. This work will be useful in designing EMHD flows in parallel plate microchannels.

关键词： electroviscous e ect electromagnetohydrodynamic (EMHD) ow generalized Maxwell uid

Structural limiting factors of mixed-valent tin oxides in photoelectrochemical application:A comparative exploration

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Journal of Energy Chemistry 2021年第5期30卷 504-511页

作者： Yalong Zou Deyu Liu Xiangrui meng Qitao Liu Yang Zhou Jianming Li Zhiying Zhao Ding Chen yongbo Kuang School of Materials Science and Engineering Hunan UniversityChangsha 410082HunanChina Ningbo Institute of MaterialsTechnology and Engineering Chinese Academy of SciencesNingbo 315201ZhejiangChina University of Chinese Academy of Sciences Beijing 100000China Petroleum Geology Research and Laboratory Center Research Institute of Petroleum Exploration&Development(RIPED)PetroChinaBeijing 100083China Department of Chemistry College of Chemistry and Chemical EngineeringXiamen UniversityXiamen 361005FujianChina

Photoelectrocatalytic(PEC)materials for harvesting solar energy can be discovered from existing photocatalytic ***,mixed valence tin oxides,a group of widely reported visible light active photocatalysts,can hardly be developed into efficient PEC *** overcome this difficulty by clarifying its origin,two typical mixed valence tin oxides,Sn^(2+):SnO_(2) microrods and porous Sn_(3)O_(4) particles were deliberately prepared as the ***^(2+):SnO_(2) microrods of less porosity exhibited a photocurrent over ten times higher than Sn_(3)O_(4) ***-electrochemical impedance spectroscopy revealed this was due to their charge kinetics difference,specifically the internal transport/-transfer responding to the ***,hydroxyl residuals from synthesis were found to be very inhibitive for the PEC efficiency as well,which was in coherence with our TGA and Raman spectroscopic *** finding experimentally proved the necessity of reconsidering the surface area,crystallinity,and defects when developing photocatalysts into efficient PEC structures.

关键词： Mixed-valence tin oxide Photoelectrochemical water splitting Nanostructure

bHLH genes polymorphisms and their association with growth traits in the Pacifi c oyster Crassostrea gigas

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Journal of Oceanology and Limnology 2020年第3期38卷 862-868页

作者： CHEN Na LI Li LI Chenghua LIN Zhihua meng Jie LIU Sheng SONG Kai BAO yongbo Zhejiang Key Laboratory of Aquatic Germplasm Resources College of Biological&Environmental SciencesZhejiang Wanli UniversityNingbo 315121China School of Marine Sciences Ningbo UniversityNingbo 315211China Key Laboratory of Experimental Marine Biology Institute of OceanologyChinese Academy of SciencesQingdao 266071China

The basic helix-loop-helix(bHLH)genes encode a large superfamily of transcription factors in the Pacific oyster(Crassostrea gigas),and play a very important role in regulation of growth and *** investigate the oyster growth traits and the associations with bHLH genes variations,we analyzed the gene polymorphisms-traits association in a wild population,and confirmed the results in another independent wild population by targeted gene re-sequencing and SNPshot *** screening the single nucleotide polymorphisms(SNPs)in three candidate genes of the bHLH family(88 bHLH genes in two wild oyster populations in total),we identified the allele CgLoblHLH4-T/G located in the exon of the CgLoblHLH4 *** allele is a non-synonymous mutation(Phe/Leu)with an extremely significant association with shell width(P<0.01)and allele G is beneficial to shell *** SNP on the CgLoblHLH4 gene might have a potential value as a genetic marker of growth traits that could be used in breeding in *** in the future.

关键词： Crassostrea gigas basic helix-loop-helix(bHLH) re-sequencing single nucleotide polymorphism(SNP)shot growth traits