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Science China Chemistry 2021年第2期64卷 274-280页

作者： Wan-Lei Yu Hao-Wen Jiang Lei Yan Zhi-Tao Feng yong-chun luo Peng-Fei Xu State Key Laboratory of Applied Organic Chemistry College of Chemistry and Chemical EngineeringLanzhou UniversityLanzhou730000China Department of Chemistry University of California-DavisOne Shields AvenueDavisCA95616USA

A photocatalytic tandem cyclization of o-alkenylbenzaldehydes using pyridinium salts as the amination reagent is described.A variety of valuable seven-membered nitrogenous heterocyclic skeletons are prepared in modest to excellent yields in concise *** transformation features mild reaction conditions and exceptional functional group *** addition,combining control experiments and density functional theory(DFT)calculations on the mechanism can explain the reaction selectivity.

关键词： photoredox catalysis nitrogen-centered radicals bicyclo[3.2.1]octane azepane 1,5-hydrogen atom transfer

A novel polyaniline/mesoporous carbon nano-composite electrode for asymmetric supercapacitor

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Chinese Chemical Letters 2010年第12期21卷 1509-1512页

作者： Jian Jun Cai Ling Bin Kong Jing Zhang yong chun luo Long Kang State Key Laboratory of Gansu Advanced Non-ferrous Metal Materials Lanzhou University of Technology Lanzhou 730050 China School of Materials Science and Engineering Lanzhou University of Technology Lanzhou 7-30050 China

A novel nano-composite of polyaniline/mesoporous carbon（PANI/CMK-3） was prepared with mesoporous carbon（CMK-3） serving as the *** asymmetric capacitors have been successfully designed by using PANI/CMK-3 composite and CMK-3 as positive and negative electrode,*** results showed that the discharge capacity of the asymmetric capacitor could reach 87.4 F/g under the current density of 5 mA/cm^2 and cell voltage of 1.4 *** energy density of the asymmetric capacitor was up to 23.8 Wh/kg with a power density of 206 W/***,PANI/CMK-3-CMK-3 asymmetric capacitor using this PANI/CMK-3 nano-composite could be activated quickly and possess high charge-discharge efficiency.

关键词： Mesoporous carbon Polyaniline Asymmetric supercapacitor Energy density

Investigating metal-organic framework as a new pseudo-capacitive material for supercapacitors

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Chinese Chemical Letters 2014年第6期25卷 957-961页

作者： Long Kang Shi-Xiong Sun Ling-Bin Kong Jun-Wei Lang yong-chun luo State Key Laboratory of Advanced Processing and Recycling of Non-ferrous Metals Lanzhou University of Technology Laboratory of Clean Energy Chemistry and Materials Lanzhou Institute of Chemical PhysicsChinese Academy of Science

A new application of metal organic framework （MOF） as a pseudo-capacitive material for supercapacitors is investigated. To this end, a simple nickel-based MOF, formulated Ni3（btc）2.12H2O, is synthesized via a hydrothermal reaction. As an electro-active material, such nickel-based MOF exhibits superior pseudo- capacitive behavior in KOH aqueous electrolyte with a high specific capacitance of 726 F g-1. Also, it displays good electrochemical stability with 94.6% of the initial capacitance over consecutive 1000 cycles. In addition, a simple asymmetric supercapacitor with a high energy density of 16.5 Wh kg-1 is successfully built using the nickel-based MOF as positive electrode and commercial activated carbon as negative electrode in KOH electrolyte.

关键词： Supercapacitor Pseudo-capacitive material Metal-organic framework Energy storage

Photoredox-Catalyzed Hydrocarboxymethylation of Alkenes

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CCS Chemistry 2021年第10期3卷 95-104页

作者： Jie Fang Qiang Hu Wan-Li Dong Guo-Qiang Xu Xiu-Qin Hu yong-chun luo Peng-Fei Xu State Key Laboratory of Applied Organic Chemistry College of Chemistry and Chemical EngineeringLanzhou UniversityLanzhou 730000 Institute of Applied Chemistry Jiangxi Academy of SciencesNanchang 330096

Direct introduction of a carboxyl group into molecules is one of the most useful methods for the preparation of carboxylic acids,which avoids the conversion of various preexisting functional groups and features good step-and ***,the methods for the direct synthesis of two-carbon added carboxylic acids from the precursors remain ***,we first report a general and mild method for the direct synthesis of a range of aliphatic acids by photoredox-catalyzed hydrocarboxymethylation of alkenes with good toleration of various functional groups in which bromoacetic acid is utilized as an ideal two-carbon synthon.

关键词： photoredox catalysis unactivated alkenes bromoacetic acid two-carbonsynthon fatty acids

Outcome of patients with acute major arterial occlusion after intra-venous thrombolysis

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Outcome of patients with acute major arterial occlusion afte...

Exploring practical methods for detecting k-nonseparability in multipartite quantum states

中国神经科学学会第十届全国学术会议

作者： yong-chun luo Bin WANG Qiang ZHANG chun-Yang LIANG Zi-Jun HE chun-Sen SHEN Affiliated Bayi Brain Hospital Beijing General Hospital Of PLA

OBJECTIVE:Intravenous fibrinolytic therapy with rt-PA for acute stroke is now widely accepted,but the effectiveness of it is not well established and required further study for patients with major arterial *** study aimed to retrospectively analyze a series of patients with major arterial occlusion who received intravenous rt-PA thrombolysis to evaluate the clinical outcome and discuss the potential ***:A retrospective study was performed to evaluate 44 patients with acute cerebral infraction due to major arterial occlusion which were admitted into Affiliated Bayi Brain Hospital of The Beijing General Hospital of PLA from January 2011 to November *** site on MRA imaging,NIHSS score at admission,24 hours after intravenous thrombolysis,discharge,and mRS score at 3 months later were ***:From January 2011 to November 2012,a total of 72 patients with acute cerebral infraction were received intravenous thromolytic therapy,44 patient had major arterial occlusion,including basilar artery occlusion in 5cases,internal carotid artery occlusion in 20 cases,middle cerebral artery occlusion in 16cases,anterior cerebral artery occlusion in 3 cases;24 hours after thrombolytic therapy,NIHSS score improvement ≥4 happened in 9 cases（13.64%）,deteriorated in 20 cases（45.45%）;at discharge,NIHSS score improvement ≥4 happened in 20 cases（45.45%）,5 patients had died in hospital（11.36%）;When 3-month follow-up,a total of 8 patients died（18.18）（including died in hospital）,and 24 patients lived with mRS ≤***:For acute stroke caused by major arterial occlusion,efficiency of intravenous rt-PA thrombolytic therapy was unsatisfactory,the racanalization rate and NIHSS score improvement were not obvious,so the best treatment in such patients still need further *** thrombolysis and mechanical thrombectomy should be assessed in experienced centers;multi-mode imaging-based individual therapy should be paid more attention.

关键词： acute stroke thrombolysis major arterial occlusion outcome

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 255-256页

作者： Shunlong luo Academy of Mathematics and Systems Science Chinese Academy of Sciences

Quantum entanglement, referred to as “spooky action at a distance” by Einstein, is not only an intriguing and fascinating feature of quantum theory challenging our classical intuitions about locality and correlations, but also has practical and profound implications for quantum technologies. Initially described by Einstein, Podolsky and Rosen, as well as by Schro¨dinger, entanglement now has become a basic and crucial ingredient for both foundational and experimental investigations of the quantum world.

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Tilting homeostatic and dyshomeostatic microglial balance in health and disease:transforming growth factor-beta1 as a critical protagonist

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Neural Regeneration Research 2025年第10期20卷 2895-2897页

作者： Nicolas Hugues Yu luo Department of Molecular and Cellular Biosciences University of CincinnatiCincinnatiOHUSA Neuroscience Graduate Program University of CincinnatiCincinnatiOHUSA Division of Immunobiology Cincinnati Children’s Hospital Medical CenterUniversity of Cincinnati College of MedicineCincinnatiOHUSA

Adult microglia,by continuously sensing changes in their environment and communicating with nearly all brain cell types,are considered to be the immune sentinels of the *** the healthy central nervous system(CNS),microglia display a unique molecular homeostatic signature(i.e.,Tmem119,P2ry12,Sall1,Siglech,Gpr34,and Hexb)(Figure 1A).

关键词： Figure signature critical

城市生活垃圾典型有机组分混合热解特性的研究

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燃料化学学报 2004年第5期32卷 563-568页

作者：温俊明池涌罗春鹏倪明江岑可法能源洁净利用与环境工程教育部重点实验室浙江大学热能工程研究所浙江杭州310027

利用自行设计的较大物量(约10g)的热重分析装置对城市生活垃圾典型有机组分(纸屑、木屑、织物、塑料、橡胶、厨余)的混合热解特性进行了实验研究,并用最小二乘法计算得到由若干平行反应组成的热解反应动力学模型,实验结果与模型计算结... 详细信息

利用自行设计的较大物量(约10g)的热重分析装置对城市生活垃圾典型有机组分(纸屑、木屑、织物、塑料、橡胶、厨余)的混合热解特性进行了实验研究,并用最小二乘法计算得到由若干平行反应组成的热解反应动力学模型,实验结果与模型计算结果吻合较好。在此基础上对城市生活垃圾典型有机组分混合热解中的交互影响和非线性规律进行了分析。结果表明,城市生活垃圾典型有机组分混合热解动力学模型由2个～4个平行反应组成;混合热解中有反应发生合并的现象;热效应和组分比例对混合物综合热解特性有显著影响。

关键词：垃圾有机组分热解热重分析动力学

P2Y1 receptor in Alzheimer’s disease

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Neural Regeneration Research 2025年第2期20卷 440-453页

作者： Shan luo Yifei Wang Tatsuhiro Hisatsune Department of Integrated Biosciences The University of TokyoKashiwaJapan

Alzheimer’s disease is the most frequent form of dementia characterized by the deposition of amyloid-beta plaques and neurofibrillary tangles consisting of hyperphosphorylated *** amyloid-beta plaques has been a primary direction for developing Alzheimer’s disease treatments in the last ***,existing drugs targeting amyloid-beta plaques have not fully yielded the expected results in the clinic,necessitating the exploration of alternative therapeutic *** evidence unravels that astrocyte morphology and function alter in the brain of Alzheimer’s disease patients,with dysregulated astrocytic purinergic receptors,particularly the P2Y1 receptor,all of which constitute the pathophysiology of Alzheimer’s *** receptors are not only crucial for maintaining normal astrocyte function but are also highly implicated in neuroinflammation in Alzheimer’s *** review delves into recent insights into the association between P2Y1 receptor and Alzheimer’s disease to underscore the potential neuroprotective role of P2Y1 receptor in Alzheimer’s disease by mitigating neuroinflammation,thus offering promising avenues for developing drugs for Alzheimer’s disease and potentially contributing to the development of more effective treatments.

关键词： astrocytes neuroinflammation P2Y1 receptor purinergic receptor

Brain endothelial cyclic GMP-AMP synthase(cGAS)-stimulator of interferon genes(STING)signaling pathway in aging and neurodegeneration

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Neural Regeneration Research 2025年第7期20卷 2005-2007页

作者： Bryan Sun Lulin Li Jian luo Palo Alto Veterans Institute for Research VA Palo Alto Health Care SystemPalo AltoCAUSA Polytrauma System of Care VA Palo Alto Health Care SystemPalo AltoCAUSA

The cyclic GMP-AMP synthase(cGAS)-stimulator of interferon genes(STING)signaling pathway has emerged as a key mediator of *** current studies primarily attribute its effects to neurons and glial cells,emerging research suggests that cGAS-STING signaling may play a critical role in cerebral vasculature,particularly in brain endothelial ***,studying the role 7of inflammation caused by the cGAS-STING pathway in brain endothelial cells could provide a more comprehensive understanding of neuroinflammatory disease and new avenues for therapeutic ***,we review the multifaceted role of global cGAS-STING signaling in various neurological and neuroinflammatory diseases and the potential contribution of cGAS-STING in brain endothelial cells.

关键词： stimulator interferon inflammation