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Combined silicosis and mixed dust pneumoconiosis with rapid progression: A case report and literature review

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World Journal of Clinical Cases 2018年第16期6卷 1164-1168页

作者： Hee-Young Yoon Yookyung Kim Heae Surng Park Chung-Won Kang yon ju ryu Division of Pulmonary and Critical Care Medicine Department of Internal Medicine College of Medicine Ewha Womans University Department of Radiology Ewha Womans University College of Medicine Department of Pathology Ewha Womans University College of Medicine Department of Occupational and Environmental Medicine Ewha Womans University College of Medicine

BACKGROUND Rapidly progressive pneumoconiosis(RPP) occasionally occurs in coal workers, particularly those with high exposure to silica. Here, we report the case of a 64-year-old male miller with RPP. CASE SUMMARY The patient had a persistent cough for one month and had been clinically diagnosed with pulmonary tuberculosis in 2011. He worked in a stone processing factory from the ages of 20 through 37 and has owned his own mill for the past 25 years. His chest radiograph showed significant increases in the size and number of lung nodules since his last follow-up in 2013. By percutaneous needle lung biopsy, the nodular lesions showed diffuse infiltration of phagocytic macrophages and birefringent crystals by polarizing microscopy. He was finally diagnosed with RPP of mixed dust pneumoconiosis combined with silicosis. CONCLUSION In this case, mixed dust pneumoconiosis with silicosis might be accelerated by persistent exposure to graindust from working in a mill environment.

关键词： Pathology Case report Pneumoconiosis Silicosis Dust Occupational diseases

On von Neumann Regularity of Commutators

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Algebra Colloquium 2024年第2期31卷 181-198页

作者： Nam Kyun Kim Tai Keun Kwak Yang Lee Sung ju ryu Nanqing Ding School of Basic Sciences Hanbat National UniversityDaejeon 34158Korea Department of Data Science Daejin UniversityPocheon 11159Korea Department of Mathematics Yanbian UniversityYanjiJilin 133002China Institute for Applied Mathematics and Optics Hanbat National University Daejeon 34158Korea Department of Mathematics Pusan National UniversityBusan 46241Korea 不详

We study the structure of rings which satisfy the von Neumann regularity of commutators,and call a ring R C-regularif ab-ba ∈(ab-ba)R(ab-ba)for all a,b in *** a C-regular ring R,we prove J(R[X])=N^(*)(R[X])=N^(*)(R)[X]=W(R)[X]■Z(R[X]),where J(A),N^(*)(A),W(A),Z(A)are the Jacobson radical,upper nilradical,Wedderburn radical,and center of a given ring A,respectively,and A[X]denotes the polynomial ring with a set X of commuting indeterminates over A;we also prove that R is semiprime if and only if the right(left)singular ideal of R is *** provide methods to construct C-regular rings which are neither commutative nor von Neumann regular,from any given ***,for a C-regular ring R,the following are proved to be equivalent:(i)R is Abelian;(ii)every prime factor ring of R is a duo domain;(ii)R is quasi-duo;and(iv)R/W(R)is reduced.

关键词： C-regular ring commutator regular ring commutative ring radical singular ideal

Comparative efficacy and optimal duration of first-line antibiotic regimens for acute otitis media in children and adolescents:a systematic review and network meta-analysis of 89 randomized clinicaltrials

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World Journal of Pediatrics 2024年第3期20卷 219-229页

作者： Min Seo Kim Jae Han Kim Seohyun ryu Seung Won Lee Dong Keon yon Eunyoung Kim Ai Koyanagi Elena Dragioti Jae Il Shin Lee Smith Samsung Advanced Institute forHealth Sciences&Technology(SAIHST) Samsung Medical CenterSungkyunkwan UniversitySeoulRepublic of Korea yonsei University Collegeof Medicine SeoulRepublicof Korea Department of Precision Medicine Sungkyunkwan University School of MedicineSuwonRepublic of Korea Center for Digital Health Medical Science Research InstituteKyung Hee University College of MedicineSeoulRepublic of Korea Evidence-Based Research Laboratory Department of Clinical Pharmacy and Pharmaceutical CareCollege of PharmacyChung-Ang UniversitySeoulRepublic of Korea Parc Sanitari Sant Joan de Deu/CIBERSAM/ISCIII Universitat de BarcelonaFundacio Sant Joan de Déu.Sant Boi de LlobregatBarcelonaSpain ICREA Pg.Lluis Companys 23BarcelonaSpain Pain and Rehabilitation Centre and Department of Medical and Health SciencesLinkoping University58185 LinkopingSweden Department of Pediatrics Yonsei University College of MedicineYonsei-ro 50Seodaemun-gu8044Seoul 03722Republic of Korea Centre for Health Performanceand WellbeingAnglia Ruskin UniversityCambridge CB11PTUK Research Laboratory Psychology of Patients Families&Health ProfessionalsDepartment of NursingSchool of Health SciencesUniversity of IoanninaIoannina 45500Greece

Introduction Antibiotic use for acute otitis media(AOM)is one of the major sources of antimicrobial ***,the effective minimal antibiotic duration for AOM remains ***,guidelines often recommend broad ranges(5-10 days)of antibiotic use,yet the clinical impact of such a wide window has not been *** We systematically searched PubMed/MEDLINE,Embase,Scopus,Web of Science,and Cochrane Library from database inception to 6 October *** meta-analysis was conducted on randomized controlled trials that assessed antibiotic treatment for AOM in children(PROSPERO CRD42020196107).Results For amoxicillin and amoxicillin-clavulanate,7-day regimens were noninferior to 10-day regimens in clinical responses[amoxicillin:risk ratio(RR)0.919(95%CI 0.820-1.031),amoxicillin-clavulanate:RR 1.108(0.957-1.282)],except for≤2 *** the third-generation cephalosporins,7-day and 10-day regimens had similar clinical responses compared to placebo[7-day:RR 1.420(1.190-1.694),10-day:RR 1.238(1.125-1.362)compared to placebo].However,5-day regimens of amoxicillin-clavulanate and third-generation cephalosporins were inferior to 10-day *** to amoxicillin,a shorter treatment duration was tolerable with *** Our findings indicated that 1O days of antibiotic use may be unnecessarily long,while the treatment duration should be longer than 5 ***,5-day regimens would be sufficient for a modest treatment *** findings revealed that the current wide range of recommended antibiotic durations may have influenced the clinical outcome of AOM,and a narrower antibiotic duration window should be re-established.

关键词： Amoxicillin-potassium Amoxicillin Antibacterial agents Cephalosporins Duration of therapy

Protein Arginine Methyltransferase 1 Ablation in Motor Neurons Causes Mitochondrial Dysfunction Leading to Age-related Motor Neuron Degeneration with Muscle Loss

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Research 2024年第1期2023卷 637-649页

作者： Hyun-Kyung So Hyebeen Kim Jinwoo Lee Chang-Lim You Chae-Eun Yun Hyeon-ju Jeong Eun-ju Jin Yunju Jo Dongryeol ryu Gyu-Un Bae Jong-Sun Kang Department of Molecular Cell Biology Sungkyunkwan University School of MedicineSuwonKorea Single Cell Network Research Center Sungkyunkwan University School of MedicineSuwonKorea Research Institute of Aging-Related Diseases AniMusCureInc.SuwonKorea Drug Information Research Institute Muscle Physiome Research CenterCollege of PharmacySookmyung Women’s UniversitySeoulKorea

Neuromuscular dysfunction is tightly associated with muscle wasting that occurs with age or due to degenerative ***,the molecular mechanisms underlying neuromuscular dysfunction are currently *** studies have proposed important roles of Protein arginine methyltransferase 1(Prmt1)in muscle stem cell function and muscle *** the current study,we set out to determine the role of Prmt1 in neuromuscular function by generating mice with motor neuron-specific ablation of Prmt1(mnKO)using *** exhibited age-related motor neuron degeneration and neuromuscular dysfunction leading to premature muscle loss and ***1 deficiency also impaired motor function recovery and muscle reinnervation after sciatic nerve *** transcriptome analysis of aged mnKO lumbar spinal cords revealed alterations in genes related to inflammation,cell death,oxidative stress,and ***,mnKO lumbar spinal cords of sciatic nerve injury model or aged mice exhibited elevated cellular stress response in motor ***,Prmt1 inhibition in motor neurons elicited mitochondrial *** findings demonstrate that Prmt1 ablation in motor neurons causes agerelated motor neuron degeneration attributing to muscle ***,Prmt1 is a potential target for the prevention or intervention of sarcopenia and neuromuscular dysfunction related to aging.

关键词： degeneration impaired prevention

Real-Time Tunable Gas Sensing Platform Based on SnO_(2) Nanoparticles Activated by Blue Micro-Light-Emitting Diodes

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Nano-Micro Letters 2024年第12期16卷 103-119页

作者： Gi Baek Nam jung-El ryu Tae Hoon Eom Seung ju Kim jun Min Suh Seungmin Lee Sungkyun Choi Cheon Woo Moon Seon ju Park Soo Min Lee Byungsoo Kim Sung Hyuk Park Jin Wook Yang Sangjin Min Sohyeon Park Sung Hwan Cho Hyuk Jin Kim Sang Eon jun Tae Hyung Lee Yeong Jae Kim Jae Young Kim Young Joon Hong Jong-In Shim Hyung-Gi Byun yongjo Park Inkyu Park Sang-Wan ryu Ho Won Jang Department of Materials Science and Engineering Seoul National UniversitySeoul 08826Republic of Korea Research Laboratory of Electronics Department of Mechanical EngineeringMassachusetts Institute of TechnologyCambridgeMA 02139USA Ming Hsieh Department of Electrical and Computer Engineering University of Southern CaliforniaLos AngelesCA 90089USA Department of Display Materials Engineering Soonchunhyang UniversityAsan 31538Republic of Korea Department of Photonics and Nanoelectronics BK21 FOUR ERICA-ACE CenterHanyang University ERICAAnsan 15588Republic of Korea Department of Nanotechnology and Advanced Materials Engineering Sejong UniversitySeoul 05006Republic of Korea Department of Electronics Information and Communication EngineeringKangwon National UniversitySamcheok 25913Republic of Korea Advance Institute of Convergence Technology Seoul National UniversitySuwon 16229Republic of Korea Department of Mechanical Engineering Korea Advanced Institute of Science and TechnologyDaejeon 34141Republic of Korea Department of Physics Chonnam National UniversityGwangju 500-757Republic of Korea

Micro-light-emitting diodes(μLEDs)have gained significant interest as an activation source for gas sensors owing to their advantages,including room temperature operation and low power ***,despite these benefits,challenges still exist such as a limited range of detectable gases and slow *** this study,we present a blueμLED-integrated light-activated gas sensor array based on SnO_(2)nanoparticles(NPs)that exhibit excellent sensitivity,tunable selectivity,and rapid detection with micro-watt level power *** optimal power forμLED is observed at the highest gas response,supported by finite-difference time-domain ***,we first report the visible light-activated selective detection of reducing gases using noble metal-decorated SnO_(2)*** noble metals induce catalytic interaction with reducing gases,clearly distinguishing NH3,H2,and ***-time gas monitoring based on a fully hardwareimplemented light-activated sensing array was demonstrated,opening up new avenues for advancements in light-activated electronic nose technologies.

关键词： Micro-LED Gas sensor array Low power consumption Metal decoration Real-time detection

Real-Time Tunable Gas Sensing Platform Based on SnO2 Nanoparticles Activated by Blue Micro-Light-Emitting Diodes

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Nano-Micro Letters 2024年第12期 111-127页

作者： Gi Baek Nam jung-El ryu Tae Hoon Eom Seung ju Kim jun Min Suh Seungmin Lee Sungkyun Choi Cheon Woo Moon Seon ju Park Soo Min Lee Byungsoo Kim Sung Hyuk Park Jin Wook Yang Sangjin Min Sohyeon Park Sung Hwan Cho Hyuk Jin Kim Sang Eon jun Tae Hyung Lee Yeong Jae Kim Jae Young Kim Young Joon Hong Jong-In Shim Hyung-Gi Byun yongjo Park Inkyu Park Sang-Wan ryu Ho Won Jang Department of Materials Science and Engineering Seoul National University Research Laboratory of Electronics Department of Mechanical Engineering Massachusetts Institute of Technology Ming Hsieh Department of Electrical and Computer Engineering University of Southern California Department of Display Materials Engineering Soonchunhyang University Department of Photonics and Nanoelectronics BK21 FOUR ERICA-ACE Center Hanyang University ERICA Department of Nanotechnology and Advanced Materials Engineering Sejong University Department of Electronics Information and Communication Engineering Kangwon National University Advance Institute of Convergence Technology Seoul National University Department of Mechanical Engineering Korea Advanced Institute of Science and Technology Department of Physics Chonnam National University

Micro-light-emitting diodes（μLEDs） have gained significant interest as an activation source for gas sensors owing to their advantages, including room temperature operation and low power consumption. However, despite these benefits, challenges still exist such as a limited range of detectable gases and slow response. In this study, we present a blue μLED-integrated light-activated gas sensor array based on SnO2nanoparticles（NPs） that exhibit excellent sensitivity, tunable selectivity, and rapid detection with micro-watt level power consumption. The optimal power for μLED is observed at the highest gas response, supported by finite-difference time-domain simulation. Additionally, we first report the visible light-activated selective detection of reducing gases using noble metal-decorated SnO2NPs. The noble metals induce catalytic interaction with reducing gases, clearly distinguishing NH3, H2, and C2H5OH. Real-time gas monitoring based on a fully hardwareimplemented light-activated sensing array was demonstrated, opening up new avenues for advancements in light-activated electronic nose technologies.

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Seasonally Varying Reference Atmospheres for East Asia

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Advances in Atmospheric Sciences 2007年第2期24卷 181-190页

作者： Byung-ju SOHN Geun-Hyeok ryu School of Earth and Environmental Sciences Seoul National University Seoul 151-747Korea

Vertical profiles of seasonally varying pressure, temperature, water vapor, and trace gases （O3, N2O, CO, CH4）, representing atmospheric conditions up to a height of 100 km over the East Asia region （30°-50°N, 110°-150°E） were constructed by using various observation data, model outputs of atmospheric thermodynamic parameters, and gaseous concentrations. Optical characteristics of the obtained East Asia reference atmospheres were compared with those from typical midlatitude summer and winter atmospheres. It was noted that, in the water vapor field, there are major differences between the two model atmospheres during the summer. The resultant impact during the summer of water vapor difference on incoming solar fluxes at the surface and emitted terrestrial fluxes at the top of the atmosphere are 14.3 W m^-2 and 6.5 W m^-2, respectively. On the other hand, the winter difference between East Asian and midlatitude atmospheres appears to be insignificant. Reference atmospheres for the spring and fall are also available. Utilizing the constructed atmospheric profiles as inputs to the radiative transfer model, it is expected that the constructed seasonally varying reference atmospheres can facilitate better descriptions of optical properties in East Asia.

关键词： East Asian reference atmosphere radiative transfer atmospheric optical property

Effects of personalized exercise prescriptions and social media delivered through mobile health on cancer survivors’physical activity and quality of life

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Journal of Sport and Health Science 2023年第6期12卷 705-714页

作者： Zan Gao Suryeon ryu Wanjiang Zhou Kaitlyn Adams Mohamed Hassan Rui Zhang Anne Blaes julian Wolfson ju Sun School of Kinesiology University of MinnesotaMinneapolisMN 55455USA Department of Kinesiology Recreationand Sport StudiesThe University of TennesseeKnoxvilleTN 37996USA Department of Pharmaceutical Care&Health Systems and Institute for Health Informatics University of MinnesotaMinneapolisMN 55455USA Department of Hematology School of MedicineUniversity of MinnesotaMinneapolisMN 55455USA School of Public Health University of MinnesotaMinneapolisMN 55455USA Department of Computer Science&Engineering University of MinnesotaMinneapolisMN 55455USA

Purpose This study aimed to examine the effects of a multi-component mobile health intervention(wearable,apps,and social media)on cancer survivors’(CS')physical activity(PA),quality of life,and PA determinants compared to exercise prescription only,social media only,and attention control *** A total of 126 CS(age=60.37±7.41 years,mean±SD)were recruited from the United *** study duration was 6 months and participants were randomly placed into 4 *** participants received a Fitbit tracker and were instructed to install its companion app to monitor their daily ***(1)received previously established weekly personalized exercise prescriptions via email,(2)received weekly Facebook health education and interacted with one another,(3)received both Conditions 1 and 2,or(4)were part of the control condition,meaning they adopted usual *** PA daily steps,quality of life(i.e.,physical health and mental health),and PA determinants(e.g.,self-efficacy,social support)were measured at baseline,3 months,and 6 *** The final sample size included 123 *** results revealed only the multi-component condition had greater improvements in PA daily steps than the control condition post-intervention(95%confidence interval(95%CI):368–2951;p<0.05).Similarly,those in the multi-component condition had significantly greater increased physical health than the control condition(95%CI:–0.41 to–0.01;p<0.05)over *** addition,the social media condition had significantly greater increased perceived social support than the control condition(95%CI:0.01–0.93;p<0.05).No other significant differences on outcomes were *** The study findings suggest that the implementation of a multi-component mobile health intervention had positive effects on CS PA steps and physical ***,offering social media intervention has the potential to improve CS perceived social support.

关键词： Daily steps Exercise app Fitbit Health wearable Physical activity determinantsTagedAPTARAEnd

Bio-printing of aligned GelMa-based cell-laden structure for muscle tissue regeneration

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Bioactive Materials 2022年第2期7卷 57-70页

作者： Hanjun Hwangbo Hyeongjin Lee Eun-ju Jin JaeYoon Lee Yunju Jo Dongryeol ryu GeunHyung Kim Department of Biomechatronics Engineering College of Biotechnology and BioengineeringSungkyunkwan University(SKKU)Suwon16419Republic of Korea Department of Molecular Cell Biology Sungkyunkwan University School of Medicine(SKKU-SOM)Suwon16419Republic of Korea Biomedical Institute for Convergence at SKKU(BICS) Sungkyunkwan UniversitySuwon16419Republic of Korea

Volumetric muscle loss(VML)is associated with a severe loss of muscle tissue that overwhelms the regenerative potential of skeletal *** engineering has shown promise for the treatment of VML injuries,as evidenced by various preclinical *** present study describes the fabrication of a cell-laden GelMa muscle construct using an in situ crosslinking(ISC)strategy to improve muscle *** obtain optimal biophysical properties of the muscle construct,two UV exposure sources,UV exposure dose,and wall shear stress were evaluated using C2C12 ***,the ISC system showed a significantly higher degree of uniaxial alignment and myogenesis compared to the conventional crosslinking strategy(post-crosslinking).To evaluate the in vivo regenerative potential,muscle constructs laden with human adipose stem cells were *** VML defect group implanted with the bio-printed muscle construct showed significant restoration of functionality and muscular *** data presented in this study suggest that stem cell-based therapies combined with the modified bioprinting process could potentially be effective against VML injuries.

关键词： GelMa bio-ink in-situ crosslinking 3D bioprinting Myogenesis