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Mental health in the virtual world:Challenges and opportunities in the metaverse era

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World Journal of Clinical Cases 2024年第17期12卷 2939-2945页

作者： yolanda López del hoyo Matilde Elices Javier Garcia-Campayo Department of Psychology and Sociology University of ZaragozaZaragoza 50009Spain Mental Health Research Group Hospital del Mar Medical Research InstituteBarcelona 08003Spain Department of Psychiatry Miguel Servet HospitalAragon Institute for Health ResearchUniversity of ZaragozaZaragoza 50009Spain

Current rates of mental illness are *** illness mainly affects females and younger age *** use of the internet to deliver mental health care has been growing since 2020 and includes the implementation of novel mental health treatments using virtual reality,augmented reality,and artificial intelligence.A new three dimensional digital environment,known as the metaverse,has emerged as the next version of the *** intelligence,augmented reality,and virtual reality will create fully immersive,experiential,and interactive online environments in the *** will use a unique avatar to do anything they do in their“real”lives,including seeking and receiving mental health *** this opinion review,we reflect on how the metaverse could reshape how we deliver mental health treatment,its opportunities,and its challenges.

关键词： Metaverse Virtual world Artificial intelligence Mental health Virtual reality Augmented reality Technology

Generation of lossy mode resonances(LMR)using perovskite nanofilms

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Opto-Electronic Advances 2024年第2期7卷 33-40页

作者： Dayron Armas Ignacio R.Matias M.Carmen lopez-Gonzalez Carlos Ruiz Zamarreño Pablo Zubiate Ignacio del Villar Beatriz Romero Electrical Electronic and Communications Engineering DepartmentPublic University of NavarraPamplona 31006Spain Institute of Smart Cities(ISC) Public University of NavarraPamplona 31006Spain Experimental Science and Technology School Rey Juan Carlos UniversityMostoles 28933Spain

The results presented here show for the first time the experimental demonstration of the fabrication of lossy mode resonance(LMR) devices based on perovskite coatings deposited on planar waveguides. Perovskite thin films have been obtained by means of the spin coating technique and their presence was confirmed by ellipsometry, scanning electron microscopy, and X-ray diffraction testing. The LMRs can be generated in a wide wavelength range and the experimental results agree with the theoretical simulations. Overall, this study highlights the potential of perovskite thin films for the development of novel LMR-based devices that can be used for environmental monitoring, industrial sensing, and gas detection, among other applications.

关键词： perovskite thin films slab waveguide lossy mode resonance

Spoon-assisted autologous particulate bone graft harvesting technique

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Chinese Journal of Plastic and Reconstructive Surgery 2024年第2期6卷 106-108页

作者： Inigo Aragon Nino Clara lopez Martínez Carolina Cuesta Urquía Agustín Pascual Camps Jose Luis del Castillo Pardo de Vera Jose Luis Cebrian Carretero Oral and Maxillofacial Surgery Department La Paz University Hospital28046 MadridSpain

Particulate bone plays a crucial role in various oral and maxillofacial surgical procedures,including reconstruction,implantation,and craniofacial *** bone and deproteinized bovine bone xenografts are the two primary resources used for such procedures,with the former demonstrating superior cost-effectiveness and reduced comorbidity rates,particularly in cases involving donor ***,a significant challenge lies in acquiring uniformly sized autologous particulate bone specimens,with existing tools often yielding coarse particles at a high ***,commercial bone xenograft solutions are frequently favored despite lower *** technical note introduces a novel technique for swiftly,safely,and efficiently obtaining autologous particulate bone *** procedure involves the use of a motor handpiece fitted with a micro drill and surgical spoon to collect the bone *** continuous irrigation with saline maintains a clear surgical field during the milling *** collected bone particles are then transferred to a metal capsule for further *** technique offers a promising solution to the challenge of inconsistent particle size associated with harvesting using traditional methods,providing surgeons with a reliable and efficient method of obtaining autologous particulate bone samples.

关键词： Bone grafting Reconstructive surgery Craniofacial surgery Implant surgery Autologous bone

Making the case for the evolving role of social media in health professions education and a literature review on the application of some in ophthalmology

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Annals of Eye Science 2024年第2期9卷 1-11页

作者： Helena Prior Filipe Mila Kostic Mildred lopez Karl Golnik West Lisbon Hospitals Center Hospital Egas MonizLisbonPortugal Egas Moniz Center for Interdisciplinary Research LisbonPortugal Continuing Education and Development in Health Professions RichboroPAUSA Coordinación de Educación en Salud Instituto Mexicano del Seguro Social(IMSS)Mexico CityMexico Department of Neurology Barrow Neurological InstitutePhoenixAZUSA Department of Ophthalmology University of CincinnatiCincinnatiOHUSA

Background and Objective:Social media(SoMe)has emerged as a tool in health professions education(HPE),particularly amidst the challenges posed by the coronavirus disease 2019(COVID-19)*** the academia’s initial skepticism SoMe has been gaining traction in supporting learning communities,and offering opportunities for innovation in *** study aims to explore the integration of SoMe in *** key components were outlined as necessary for a successful integration,and include designing learning experiences,defining educator roles,selecting appropriate platforms,and establishing educational ***:This article stemmed from the online Teaching Skills Series module on SoMe in education from the Ophthalmology Foundation,and drew upon evidence supporting learning theories relevant to SoMe integration and models of ***,we conducted a literature review considering Englishlanguage articles on the application of SoMe in ophthalmology from PubMed over the past *** Content and Findings:Early adopters of SoMe platforms in HPE have leveraged these tools to enhance learning experiences through interaction,dialogue,content sharing,and active learning *** integrating SoMe into educational programs,both online and in-person,educators can overcome time and geographical constraints,fostering more diverse and inclusive learning *** consideration is,however,necessary to address potential limitations within ***:This article lays groundwork for expanding SoMe integration in HPE design,emphasizing the supportive scaffold of various learning theories,and the need of furthering robust research on examining its advantages over traditional educational *** literature review underscores an ongoing multifaceted,random application of SoMe platforms in ophthalmology *** advocate for an effective incorporation of SoMe in HPE education,with the need to comply with good educational practice.

关键词： Social media(SoMe) health professions education(HPE) active learning social learning technology enhanced learning

Are we ready for telemonitoring inflammatory bowel disease?A review of advances,enablers,and barriers

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World Journal of Gastroenterology 2023年第7期29卷 1139-1156页

作者： Javier del hoyo Mónica Millán Alejandro Garrido-Marín Mariam Aguas Department of Gastroenterology La Fe University and Polytechnic HospitalValencia 46026Spain Department of Surgery La Fe University and Polytechnic HospitalValencia 46026Spain Health Research Institute La Fe La Fe University and Polytechnic HospitalValencia 46026Spain

This review summarizes the evidence about telemonitoring in patients with inflammatory bowel disease(IBD). To give an overview of the advances performed, as well as the enablers and barriers which favoured/hindered telemonitoring implementation. We performed a literature search in Pub Med, EMBASE, MEDLINE, Cochrane Database, Web of Science and Conference Proceedings. Titles and abstracts published up to September 2022 were screened for a set of inclusion criteria: telemonitoring intervention, IBD as the main disease, and a primary study performed. Ninety-seven reports were selected for full review. Finally, 20 were included for data extraction and critical appraisal. Most studies used telemonitoring combined with tele-education, and programs evolved from home telemanagement systems towards web portals through m Health applications. Web systems demonstrated patients’ acceptance, improvement in quality of life, disease activity and knowledge, with a good cost-effectiveness profile in the short-term. Initially, telemonitoring was almost restricted to ulcerative colitis, but new patient reported outcome measures, home-based tests and mobile devices favoured its expansion to different patients’ categories. However, technological and knowledge advances led to legal, ethical, economical and logistic issues. Standardization of remote healthcare is necessary, to improve the interoperability of systems as well as to address liability concerns and users’ preferences. Telemonitoring IBD is well accepted and improves clinical outcomes at a lower cost in the short-term. Funders, policymakers, providers, and patients need to align their interests to overcome the emerging barriers for its full implementation.

关键词： Inflammatory bowel disease Telemedicine Telemonitoring Information and communication technology Crohn´s disease Ulcerative colitis

Recent Advances on Early-Stage Fire-Warning Systems: Mechanism, Performance, and Perspective

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Nano-Micro Letters 2022年第12期14卷 106-136页

作者： Xiaolu Li Antonio Vazquez-lopez Jose Sanchez del Rio Saez De-Yi Wang IMDEA Materials Institute C/Eric Kandel228906 GetafeMadridSpain E.T.S.de Ingenieros de Caminos Universidad Politecnica de MadridCalle Profesor Aranguren 328040 MadridSpain Departamento de Ingenieria Electrica Electronica Automatica y Fisica AplicadaETSIDIUniversidad Politecnica de MadridRonda de Valencia 328012 MadridSpain

Early-stage fire-warning systems(EFWSs)have attracted significant attention owing to their superiority in detecting fire situations occurring in the pre-combustion *** progress on EFWSs has been achieved recently,and they have presented a considerable possibility for more evacuation time to control constant unintentional fire hazards in our daily *** review mainly makes a comprehensive summary of the current EFWSs,including the working mechanisms and their *** to the different working mechanisms,fire alarms can be classified into graphene oxide-based fire alarms,semiconductor-based fire alarms,thermoelectric-based fire alarms,and fire alarms on other working ***,the challenge and prospect for EFWSs are briefly provided by comparing the art of state of fire *** work can propose a more comprehensive understanding of EFWSs and a guideline for the cutting-edge development direction of EFWSs for readers.

关键词： Smart thermosensitive fire sensors Working mechanism Response time Signal conversion

Polarization conversion using customized subwavelength laser-induced periodic surface structures on stainless steel

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Photonics Research 2022年第9期10卷 2024-2031页

作者： MAHMOUD H.ELSHORBAGY LUIS MIGUEL SÁNCHEZ-BREA JERÓNIMO BUENCUERPO JESÚS del hoyo ÁNGELA SORIA-GARCÍA VERÓNICA PASTOR-VILLARRUBIA ALEJANDRO SAN-BLAS AINARA RODRÍGUEZ SANTIAGO MIGUEL OLAIZOLA JAVIER ALDA Grupo Complutense deÓptica Aplicada Departamento deÓpticaFacultad de Ciencias FıÂsicasUniversidad Complutense de MadridPlaza de las Ciencias S.N.28040 MadridSpain Physics Department Faculty of ScienceMinia University61519 El-MinyaEgypt L’Institut Photovoltaïque d’Île-de-France(IPVF) 18 Bd Thomas Gobert91120 PalaiseauFrance Ceit-Basque Research and Technology Alliance(BRTA) Manuel Lardizabal 1520018 Donostia/San SebastiánSpain Universidad de Navarra TecnunManuel Lardizabal 1320018 Donostia/San SebastiánSpain

Stainless steel is a basic raw material used in many *** can be customized by generating laser-induced periodic surface structure(LIPSS)as subwavelength ***,we present the capabilities of an LIPSS on stainless steel to modify the polarization state of the reflected radiation at the IR *** structures have been modeled using the finite element method and fabricated by femtosecond laser *** Stokes parameters have been obtained experimentally and a model for the shape has been used to fit the simulated Stokes values to the experimental *** birefringence of the LIPSS is analyzed to explain how they modify the polarization state of the incoming *** find the geometry of the subwavelength grating that makes it work as an optical retarder that transforms a linearly polarized light into a circularly polarized *** addition,the geometrical parameters of the LIPSS are tuned to selectively absorb one of the components of the incoming light,becoming a linear axial *** selecting the geometrical parameters and orientation of the fabricated LIPSS makes it possible to obtain an arbitrary pure polarization state when illuminated by a pure linearly polarized state oriented at an azimuth of 45°.The overall reflectance of these transformations reaches values close to 60%with respect to the incident intensity,which is the same reflectivity obtained for non-nanostructured stainless steel flat surfaces.

关键词： steel laser polarization

A prospective analysis of factors that influence weight loss in patients undergoing radiotherapy

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Chinese Journal of Cancer 2014年第4期33卷 204-210页

作者： Jon Cacicedo Francisco Casquero Lorea Martinez-Indart Olga del hoyo Alfonso Gomez de Iturriaga Arturo Navarro Pedro Bilbao Department of Radiation Oncology Cruces University Hospital Department of Statistics and Epidemiology Cruces University Hospital Department of Radiation Oncology Catalan Institute of OncologyL'Hospitalet de Llobregat

Malnutrition occurs frequently in patients with ***,a variety of nutritional and tumorrelated factors must be taken into account in these *** this relationship,we aimed to prospectively evaluate the risk factors that influence weight loss in patients undergoing radiotherapy with oral nutritional supplementation and dietetic *** loss of 74 patients during radiotherapy and 1 month after treatment was *** such as age,gender,tumor location,tumor stage,Eastern Cooperative Oncology Group performance status(ECOG PS)score,and the use of chemotherapy were analyzed to evaluate their influence on weight *** patients underwent oral nutritional supplementation and dietetic ***-six(65.7%)patients lost weight,with a mean weight loss of(4.73±3.91)kg,during *** 1 month after treatment,45(66.2%)patients lost weight,presenting a mean weight loss of(4.96±4.04)kg,corresponding to a(6.84±5.24)%net reduction from their baseline *** and neck cancer patients had a mean weight loss of(3.25±5.30)kg,whereas the remaining patients had a mean weight loss of(0.64±2.39)kg(P=0.028)during *** the multivariate analysis,the head and neck tumor location(P=0.005),use of chemotherapy(P=0.011),and ECOG PS score of 2-3(P=0.026)were considered independent risk *** status and parameters,such as tumor location(especially the head and neck),the use of chemotherapy,and the ECOG PS score,should be evaluated before radiotherapy because these factors can influence weight loss during radiotherapy and 1 month after treatment.

关键词：癌症患者放疗减肥头颈部肿瘤平均体重营养不良危险因素营养补充

Regulation of the New Arabidopsis Imprinted Gene AtBMIIC Requires the Interplay of Different Epigenetic Mechanisms

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Molecular Plant 2012年第1期5卷 260-269页

作者： Fabian Bratzel ChaoYang Alexandra Angelova Gema lopez-Torrejon Marcus Koch Juan Carlos del Pozo Myriam Calonje Centre for Organismal Studies Heidelberg Department of Biodiversity and Plant Systernatics University of Heidelberg Im Neuenheirner Feld 345 69120 Heidelberg Germany Centro de Biotecnologia y Genomica de Plantas （UPM-INIA） Campus de Montegancedo s/n Boadilla del Monte 28660 Madrid Spain

Recently, it has been shown that plants contain homologs to the animal Polycomb repressive complex I （PRC1） components BM11 and RINGIA/B. In Arabidopsis, there are three BMIl-like genes, two of which, AtBMIIA and B, are required during post-embryonic plant growth to repress embryonic traits and allow cell differentiation. However, little is known about the third BMIl-like gene, AtBMIIC. In this work, we show that AtBMIIC is only expressed during endosperm and stamen development. AtBMIIC is an imprinted gene expressed from the maternal allele in the endosperm but bialleli- cally expressed in stamen. We found that the characteristic expression pattern of AtBMIIC is the result of a complex epigenetic regulation that involves CG DNA methylation, RNA-directed non-CG DNA methylation （RdDM）, and PcG activity. Our results show the orchestrated interplay of different epigenetic mechanisms in regulating gene expression throughout development, shedding light on the current hypotheses for the origin and mechanism of imprinting in plant endosperm.

关键词： Epigenetics gene silencing development Polycomb Group proteins.