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Stiffness and toughness of soft/stiff suture joints in biological composites

Applied Mathematics and Mechanics(English Edition) 2022年第10期43卷 1469-1484页

作者： Dong WU yixing huang Ming LEI Zeang ZHAO Xiaogang GUO Daining FANG State Key Laboratory for Turbulence and Complex Systems&Center for Applied Physics and Technology College of EngineeringPeking UniversityBeijing 100871China Beijing Key Laboratory of Lightweight Multi-functional Composite Materials and Structures Beijing Institute of TechnologyBeijing 100081China State Key Laboratory of Explosion Science and Technology Beijing Institute of TechnologyBeijing 100081China School of Astronautics Northwestern Polytechnical UniversityXi’an 710072China

Biological composites can overcome the conflict between strength and toughness to achieve unprecedented mechanical properties in engineering *** suture joint,as a kind of heterogeneous architecture widely existing in biological tissues,is crucial to connect dissimilar components and to attain a tradeoff of all-sided functional ***,the suture joints have attracted many researchers to theoretically investigate their mechanical ***,most of the previous models focus on the sutural interface between two chemically similar stiff phases with(or without)a thin adhesive layer,which are under the framework of linear elasticity and small ***,a general model based on the finite deformation framework is proposed to explore the stiffness and toughness of chemically dissimilar suture joints connecting soft and stiff *** tension tests are conducted to investigate the tensile response of the suture joints,and finite element simulations are implemented to explore the underlying mechanisms,considering both material nonlinearity and cohesive properties of the *** failure modes are quantitively captured by our *** stored elastic energy in the soft phase competes with the energy dissipation due to the interface debonding,which controls the transition among different failure *** toughness of the suture joints depends on not only the intrinsic strengths of the constituent materials and their cohesive strength,but also the interfacial *** work provides the structureproperty relationships of the soft/stiff suture joints and gives a foundational guidance of mechanical design towards high-performance bioinspired composites.

关键词： suture joint biological composite finite deformation toughness

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Artificial periosteum in bone defect repair--A review

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Chinese Chemical Letters 2017年第9期28卷 1801-1807页

作者： Quan Wang Jianxiang Xu Haiming Jin Wenhao Zheng Xiaolei Zhang yixing huang Zhiyong Qian Department of Orthopaedics The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University Wenzhou 325027 China Department of Oncology and Cancer Center West China Hospital Sichuan University Chengdu 610041 China Zhejiang Provincial Key Laboratory of Orthopaedics Wenzhou 325027 China

Periosteum is a thin membrane that encases the surfaces of most *** is composed of an outer fibrous layer contains longitudinally oriented cells and collagen fibers and an inner cambial layer that consists of multipotent mesenchymal stem cells（MSCs）and osteogenic progenitor *** has a function of regulating cell and collagen arrangement,which is important to the integrity,modelling and remodelling of bone,particularly during bone defect *** from autograft and allograft,artificial periosteum,or tissue-engineered periosteum mimicking native periosteum in structure or function,made up of small intestinal submucosa,acellular dermis,induced membrane,cell sheets,and polymeric scaffolds,and so on,has been developed to be used in bone defect *** this review,we classify the artificial periosteum into three approaches based on the material source,that is,native tissues,scaffoldfree cell sheets and scaffold-cell ***,methods and efficacy of each approach are *** obstacles and enabling technologies for future directions are also discussed.

关键词： Artificial periosteum Bone defect Tissue engineering Extracellular matrix Biomimetic

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3D porous acellular cartilage matrix scaffold with surface mediated sustainable release of TGF-β3 for cartilage engineering

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Chinese Chemical Letters 2020年第7期31卷 1797-1800页

作者： yixing huang Xingfang Yu Linjie He Xin Liao Shuo Wang Zhiyong Qian Liyan Shen Key Laboratory of Orthopedics of Zhejiang Province Department of OrthopedicsThe Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical UniversityWenzhou 325000China College of Pharmacy Zhejiang Pharmaceutical CollegeNingbo 315199China State Key Laboratory of Biotherapy and Cancer Center West China HospitalWest China Medical SchoolSichuan Universityand Collaborative Innovation Center for BiotherapyChengdu 610041China

Acellular tissue matrix scaffolds are much closer to tissue’s complex natural structure and biological characteristics,thus assess great advantages in cartilage *** used rabbit costal cartilage to prepare acellular microfilaments and further 3D porous acellular cartilage scaffold via ***(_L-lysine)/hyaluronic acid(PLL/HA)multilayer film was then built up onto the surface of the resulting porous ***,TGF-β3 was loaded into the PLL/HA multilayer film coated scaffold to obtain a 3D porous acellular cartilage scaffold with sustained releasing of TGF-β3 up to 60 *** success of this project will provide a new way for the treatment of articular cartilage ***,the anchoring and on-site sustained releasing of growth factors mediated by polyelectrolyte multilayered film can also provide a new method for improving the biocompatibility and the biofunctionality for other implanted biomaterials.

关键词： Acellular cartilage matrix scaffold TGF-β3 Polyelectrolyte multilayer film Sustainable release

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On the monolayer dispersion behavior of Co_(3)O_(4)on HZSM-5 support:designing applicable catalysts for selective catalytic reduction of nitrogen oxides by ammonia

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Frontiers of Chemical Science and Engineering 2023年第11期17卷 1741-1754页

作者： Yufeng Yang Lihong Zhang Tao Song yixing huang Xianglan Xu Junwei Xu Xiuzhong Fang Qing Wang Haiming Liu Xiang Wang Key Laboratory of Jiangxi Province for Environment and Energy Catalysis School of Chemistry and Chemical EngineeringNanchang UniversityNanchang 330031China Shanghai Tech University School of Physical Science&TechnologyShanghai 201210China

Based on monolayer dispersion theory,Co_(3)O_(4)/ZSM-5 catalysts with different loadings have been prepared for selective catalytic reduction of nitrogen oxides by ***_(3)O_(4)can spontaneously disperse on HZSM-5 support with a monolayer dispersion threshold of 0.061 mmol 100 m^(-2),equaling to a weight percentage around 4.5%.It has been revealed that the quantities of surface active oxygen(O_(2)^(-))and acid sites are crucial for the reaction,which can adsorb and activate NO_(x)and NH_(3)reactants *** the monolayer dispersion threshold,Co_(3)O_(4)is finely dispersed as sub-monolayers or monolayers and in an amorphous state,which is favorable to generate the two kinds of active sites,hence promoting the performance of ammonia selective catalytic reduction of nitrogen ***,the formation of crystalline Co_(3)O_(4)above the capacity is harmful to the reaction performance.4%Co_(3)O_(4)/ZSM-5,the catalyst close to the monolayer dispersion capacity,possesses the most abundant active O_(2)^(-)species and acidic sites,thereby demonstrating the best reaction performance in all the *** is proposed the optimal Co_(3)O_(4)/ZSM-5 catalyst can be prepared by loading the capacity amount of Co_(3)O_(4)onto HZSM-5 support.

关键词： Co_(3)O_(4)/ZSM-5 NO_(x)-SCR by NH_(3) monolayer dispersion threshold effect surface acid sites surface active O_(2)^(-)anions

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A posteromedial approach for open reduction and internal fixation of posteromedial tibial plateau fracture

A posteromedial approach for open reduction and internal fix...

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2016年浙江省骨科学学术年会

作者： yixing huang Jun Pan 温州医科大学附属第二医院

Purpose:The aim of this study was to evaluate the clinical outcomes of patients with posteromedial tibial plateau fractures treated by open reduction and internal fixation(ORIF) through a posteromedial ***:Thirty-six patients with posteromedial tibial plateau fracture underwent ORIF through a posteromedial approach and were retrospectively *** X-ray pictures and CT images were *** there were 11 cases of posteromedial tibial plateau fracture and 25 cases of posteromedial and posterolateral tibial plateau *** the patients were treated surgically with posteromedial *** clinical outcomes were assessed according to the Rasmussen knee function grading ***:The patients were followed-up for an average of 17.5 months(range,12-32 months).All the fractures attained satisfactory *** major complications were *** to the Rasmussen knee function grading system,the results were graded as excellent in 21 cases,good in 13 cases,fair in 2 *** rate of excellent and good results was 94.4%.Conclusion:The posteromedial approach in our opinion is the best option to treat the posteromedial tibial plateau fractures because it can provide direct visualization of the fracture site and avoid dissection of neurovascular bundle in the popliteal fossa area with minimal soft tissue injury.

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城市景观要素演变探讨

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城市发展研究 2008年第5期15卷 53-56页

作者：刘强黄义雄福建师范大学地理科学学院

城市景观随着城市的发展而发生演变。受城市功能转变和发展理念影响,城市道路发展迅速,决定了城市景观格局的变化,并逐渐取代街区成为城市景观中的背景。街区面积减小,破碎化程度加大,逐渐转变为斑块。同时休憩绿地和生态绿地等的大量... 详细信息

城市景观随着城市的发展而发生演变。受城市功能转变和发展理念影响,城市道路发展迅速,决定了城市景观格局的变化,并逐渐取代街区成为城市景观中的背景。街区面积减小,破碎化程度加大,逐渐转变为斑块。同时休憩绿地和生态绿地等的大量出现导致斑块多样化,提高了城市景观异质性。地下市政设施的发展分担了廊道的部分功能,地表廊道以承担生态功能为主。

关键词：城市景观景观格局景观要素演变

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某10层综合楼组合纠倾技术

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建筑技术 2000年第6期31卷 374-375,409页

作者：黄翊兴黄泽德贵州省建一公司

贵州省都匀市北郊某10层综合楼,平面尺寸为47.4m×9.3m,建筑面积4919m2.该楼首层为层高3.6m的半地下室,下部3层为钢筋混凝土框架结构,其上7层为砖混结构;基础采用混凝土反梁式筏板,梁高1.2m,筏板厚0.5m,其下设有0.5m厚砂垫层.

关键词：综合楼组合纠倾技术建筑物

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具有抗细菌黏附和杀菌双重功能的(HA/CHI-Van)5涂层的制备

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温州医科大学学报 2020年第9期50卷 705-711页

作者：廖鑫黄义星温州医科大学附属第二医院育英儿童医院骨科浙江温州325027

目的:研究开发一种涂覆(HA/CHI-Van)5多层膜结构的骨科内植入物以用于预防骨内植入物感染。方法:将透明质酸(HA)和壳聚糖-万古霉素(CHI-Van)溶液进行层层自组装,制备得到(HA/CHI-Van)5多层膜结构;通过zeta电位检测组装过程,通过活细菌... 详细信息

目的:研究开发一种涂覆(HA/CHI-Van)5多层膜结构的骨科内植入物以用于预防骨内植入物感染。方法:将透明质酸(HA)和壳聚糖-万古霉素(CHI-Van)溶液进行层层自组装,制备得到(HA/CHI-Van)5多层膜结构;通过zeta电位检测组装过程,通过活细菌染色实验评价多层膜的抗细菌黏附效果,通过越狱实验和FE-SEM实验检测体外抗菌效果。SD大鼠随机分为空白组、(HA/CHI-Van)5组和假手术组,并以X线、MicroCT、骨组织切片等方法检测该材料的体内动物实验效果。结果:每次组装不同的单层,zeta电位交替变化,证明多层膜组装成功。活细菌染色实验显示多层膜结构中的CHI具有一定的抗细菌黏附作用。越狱实验和FE-SEM实验证明(HA/CHI-Van)5多层膜结构在体外具有良好的抗菌作用。在体外实验中,(HA/CHI-Van)5组的X线评分为0.7,而空白组的评分为12.3,(HA/CHI-Van)5组在骨密度、骨小梁数量、骨体积分数、骨组织切片方面均优于空白组(均P0.05)。结论:通过在骨科内植入物表面涂覆(HA/CHI-Van)5多层膜结构能够获得一定的抗细菌黏附功能和良好的抗菌作用,可以预防骨内植入物感染。

关键词：植入物感染细菌层层自组装抗生素

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中国海油一体化企业智慧管理平台建设

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油气储运 2018年第7期37卷 741-750页

作者：曹闯明黄亦星刘荣董绍华中海石油气电集团有限责任公司北京中盈安信技术服务股份有限公司中国石油大学(北京)管道技术与安全研究中心

随着物联网、云计算、大数据等新技术的发展,为了满足国家推进信息化和工业化高层次、深度结合的迫切需求,企业智慧平台成为企业转型升级的关键要素。以中海石油气电集团有限责任公司信息管理平台开发为例,按照厚平台、易应用的建设原则... 详细信息

随着物联网、云计算、大数据等新技术的发展,为了满足国家推进信息化和工业化高层次、深度结合的迫切需求,企业智慧平台成为企业转型升级的关键要素。以中海石油气电集团有限责任公司信息管理平台开发为例,按照厚平台、易应用的建设原则,提出了三维空间交互的企业智慧平台的架构。基于管道数据融合、三维应急决策支持技术,开发了生产数据采集、智慧视频监控、安全生产运营管理与移动应用、节能管理智能化等智能系统;基于物联网、云计算、大数据及移动应用技术,开发了厂/场级无线网络系统、总部级节能减排系统,建设了数据中心,集成了云架构监控支持平台。该平台具有科学性、先进性、智能化的显著特点,通过工程实践表明:企业智慧平台可全面推动企业生产方式和管控模式的改变,进而提高企业安全环保、节能减排及绿色低碳水平,以及企业的生产效益。

关键词：中国海油智慧平台数字化信息化智能化管控模式 WLAN 节能减排

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在依法治国进程中增强党的依法执政本领

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沈阳干部学刊 2018年第6期20卷 20-23页

作者：黄艺星王忠才中共沈阳市苏家屯区委党校辽宁沈阳110117 中共沈阳市委党校辽宁沈阳110036

在全面推进依法治国的进程中必须始终坚持党的领导,而依法执政是新时期加强和改进党的领导方式的主要内容,是增强党的执政本领的重要组成部分。依法治国必先依法执政,依法执政必须依规治党,依宪执政则是依法执政的首要任务,领导干部法... 详细信息

在全面推进依法治国的进程中必须始终坚持党的领导,而依法执政是新时期加强和改进党的领导方式的主要内容,是增强党的执政本领的重要组成部分。依法治国必先依法执政,依法执政必须依规治党,依宪执政则是依法执政的首要任务,领导干部法治思维的培养是依法执政的实现途径。依法执政与依法治国二者在理论逻辑与实践要求上密不可分、相互联系。

关键词：依法治国依法执政依规治党

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