检索结果-南通市图书馆

Plastid RNA editing reduction accompanied with genetic variations in Cymbidium,a genus with diverse lifestyle modes

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Plant Diversity 2022年第3期44卷 316-321页

作者： Mengqing Zhe Le Zhang Fang Liu yiwei huang Weishu Fan Junbo Yang Andan Zhu Germplasm Bank of Wild Species Kunming Institute of BotanyChinese Academy of SciencesKunmingYunnan 650201China University of Chinese Academy of Sciences Beijing 100049China School of Life Sciences Yunnan UniversityKunmingYunnan 650500China

Recent sequencing efforts have broadly uncovered the evolutionary trajectory of plastid genomes(plastomes)of flowering plants in diverse habitats,yet our knowledge of the evolution of plastid posttranscriptional modifications is *** this study,we generated 11 complete plastomes and performed ultra-deep transcriptome sequencing to investigate the co-evolution of plastid RNA editing and genetic variation in Cymbidium,a genus with diverse trophic *** size and gene content is reduced in terrestrial and green mycoheterotrophic orchids relative to their epiphytic *** could be partly due to extensive losses and pseudogenization of ndh genes for the plastid NADH dehydrogenase-like complex,but independent pseudogenization of ndh genes has also occurred in the epiphyte ***,which was reported to use strong crassulacean acid metabolism *** editing sites are abundant but variable in number among Cymbidium *** nearly twofold variation in editing abundance is mainly due to extensive reduction of ancestral editing sites in ndh transcripts of terrestrial,mycoheterotrophic,and *** *** co-occurrence of editing reduction and pseudogenization in ndh genes suggests functional constraints on editing machinery may be relaxed,leading to nonrandom loss of ancestral edited sites via reduced editing *** study represents the first systematic examination of RNA editing evolution linked to plastid genome variation in a single *** also propose an explanation for how genomic and posttranscriptional variations might be affected by lifestyle-associated ecological adaptation strategies in Cymbidium.

关键词： RNA editing Plastomes ndh genes Lifestyle

A Detected Case of Avian Influenza H9N2 from Influenza-Like Illness Surveillance--Hunan Province, 2020

在线全文

学校读者我要写书评

暂无评论

China CDC weekly 2020年第36期2卷 700-703页

作者： Siyu Zhang Chaoyang huang Yingying Mo Zhoujian Wu Haizhen Li yiwei huang Fuqiang Liu Lidong Gao Hunan Provincial Center for Disease Control and Prevention ChangshaHunanChina Hunan Provincial Key Laboratory of Microbial Molecular Biology ChangshaHunanChina Xiangxi Tujia and Miao Autonomous Prefectural Center for Disease Control and Prenvention JishouHunanChina Jishou Municipal Center for Disease Control and Prevention JishouHunanChina.

Jishou Municipal Center for Disease Control and Prevention(Jishou CDC)received a phone call at 7:30 *** April 24,2020 from Xiangxi Tujia and Miao Autonomous Prefectural CDC(Xiangxi CDC)that avian influenza A/H9N2 virus was detected by quantitative reverse transcription-polymerase chain reaction(RT-PCR)from the throat swab sample of an influenza-like illness in an outpatient in the Xiangxi Traditional Chinese Medicine Hospital.

关键词： Hunan Xiang illness

A multilayer network diffusion-based model for reviewer recommendation

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Physics B 2024年第3期33卷 700-717页

作者：黄羿炜徐舒琪蔡世民吕琳媛 Institute of Fundamental and Frontier Sciences University of Electronic Science and Technology of ChinaChengdu 611731China Yangtze Delta Region Institute (Huzhou) University of Electronic Science and Technology of ChinaHuzhou 313001China Institute of Dataspace Hefei Comprehensive National Science CenterHefei 230088China Big Data Research Center University of Electronic Science and Technology of ChinaChengdu 611731China School of Computer Science and Engineering University of Electronic Science and Technology of ChinaChengdu 611731China School of Cyber Science and Technology University of Science and Technology of ChinaHefei 230026China

With the rapid growth of manuscript submissions,finding eligible reviewers for every submission has become a heavy *** systems are powerful tools developed in computer science and information science to deal with this ***,most existing approaches resort to text mining techniques to match manuscripts with potential reviewers,which require high-quality textual information to perform *** this paper,we propose a reviewer recommendation algorithm based on a network diffusion process on a scholar-paper multilayer network,with no requirement for textual *** network incorporates the relationship of scholar-paper pairs,the collaboration among scholars,and the bibliographic coupling among *** results show that our proposed algorithm outperforms other state-of-the-art recommendation methods that use graph random walk and matrix factorization and methods that use machine learning and natural language processing,with improvements of over 7.62%in recall,5.66%in hit rate,and 47.53%in ranking *** work sheds light on the effectiveness of multilayer network diffusion-based methods in the reviewer recommendation problem,which will help to facilitate the peer-review process and promote information retrieval research in other practical scenes.

关键词： reviewer recommendation multilayer network network diffusion model recommender systems complex networks

High-quality Cymbidium mannii genome and multifaceted regulation of crassulacean acid metabolism in epiphytes

在线全文

学校读者我要写书评

暂无评论

Plant Communications 2023年第5期4卷 191-207页

作者： Weishu Fan Zheng-Shan He Mengqing Zhe Jing-Qiu Feng Le Zhang yiwei huang Fang Liu Jia-Lin huang Ji-Dong Ya Shi-Bao Zhang Jun-Bo Yang Andan Zhu De-Zhu Li Germplasm Bank of Wild Species Kunming Institute of BotanyChinese Academy of SciencesKunmingYunnan 650201China Kunming College of Life Science University of Chinese Academy of SciencesKunmingYunnan 650201China Key Laboratory for Economic Plants and Biotechnology Kunming Institute of BotanyChinese Academy of SciencesKunmingYunnan 650201China Yuxi Normal University YuxiYunnan 653100China

Epiphytes with crassulacean acid metabolism(CAM)photosynthesis are widespread among vascular plants,and repeated evolution of CAM photosynthesis is a key innovation for micro-ecosystem ***,we lack a complete understanding of the molecular regulation of CAM photosynthesis in ***,we report a high-quality chromosome-level genome assembly of a CAM epiphyte,Cymbidium mannii(Orchidaceae).The 2.88-Gb orchid genome with a contig N50 of 22.7 Mb and 27192 annotated genes was organized into 20 pseudochromosomes,82.8%of which consisted of repetitive *** expansions of long terminal repeat retrotransposon families have made a major contribution to the evolution of genome size in Cymbidium *** reveal a holistic scenario of molecular regulation of metabolic physiology using high-resolution transcriptomics,proteomics,and metabolomics data collected across a CAM diel *** of rhythmically oscillating metabolites,especially CAM-related products,reveal circadian rhythmicity in metabolite accumulation in *** analysis of transcript and protein level regulation revealed phase shifts during the multifaceted regulation of circadian ***,we observed diurnal expression of several core CAM genes(especially bCA and PPC)that may be involved in temporal fixation of carbon *** study provides a valuable resource for investigating post-transcription and translation scenarios in ***,an Orchidaceae model for understanding the evolution of innovative traits in epiphytes.

关键词： epiphytes CAM photosynthesis multi-omics phase shifts rhythmic metabolites

Comparison of robot-assisted partial nephrectomy with KangDuo surgical system vs. the da Vinci Si system: Quality of life and medium-term oncological outcomes

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中华医学杂志(英文版) 2024年第22期137卷 2024 Sep 27页

作者： Li Zhihua huang yiwei Wang Xiang Zhang Meng Fan Shubo Liu Fan Xiong Shengwei Yang Kunlin Guan Hua Li Xuesong Zhou Liqun Department of Urology Peking University First Hospital Institute of Urology Peking University National Urological Cancer Centre Beijing China Department of Nursing Peking University First Hospital Peking University Beijing China

The S190R mutation in the hemagglutinin protein of pandemic H1N1 2009 influenza virus increased its pathogenicity in mice

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Science China(Life Sciences) 2018年第7期61卷 836-843页

作者： Yongkun Chen Tian Bai Wenfei Zhu Rongbao Gao Zhihong Deng Yi Shi Shumei Zou yiwei huang Xiyan Li Fangcai Li Zhaomin Feng Tao Chen Jing Yang Dayan Wang Lidong Gao Yuelong Shu National Institute for Viral Disease Control and Prevention Collaboration Innovation Center for Diagnosis and Treatment of Infectious DiseasesChinese Center for Disease Control and PreventionKey Laboratory for Medical VirologyNational Health and Family Planning CommissionBeijing 102206China Hunan Provincial Center for Disease Control and Prevention Changsha 410005China CAS Key Laboratory of Pathogenic Microbiology and Immunology Institute of MicrobiologyChinese Academy of SciencesBeijing 100101 China School of Public Health(Shenzhen) Sun Yat-sen UniversityGuangzbou 510275China

Human influenza viruses preferentially bind to sialic acid-α2,6-galactose (SAα2,6Gal) receptors, which are predominant in human upper respiratory epithelia, whereas avian influenza viruses preferentially bind to SAα2,3Gal receptors. However, variants with amino acid substitutions around the receptor-binding sites of the hemagglutinin (HA) protein can be selected after several passages of human influenza viruses from patients’ respiratory samples in the allantoic cavities of embryonated chicken eggs. In this study, we detected an egg-adapted HA S190R mutation in the pandemic H1N1 virus 2009 (pdmH1N1), and evaluated the effects of this mutation on receptor binding affinity and pathogenicity in mice. Our results revealed that residue 190 is located within the pocket structure of the receptor binding site. The single mutation to arginine at position 190 slightly increased the binding affinity of the virus to the avian receptor and decreased its binding to the long human α2,6-linked sialic acid receptor. Our study demonstrated that the S190R mutation resulted in earlier death and higher weight loss in mice compared with the wild-type virus. Higher viral titers at 1 dpi (days post infection) and diffuse damage at 4 dpi were observed in the lung tissues of mice infected with the mutant virus.

关键词： pandemic HIN1 2009 influenza virus egg adaptation HA mutation receptor binding domain pathogenicity mice

儿童友好型城市建设背景下景观设计师的职责和角色转变

在线全文

学校读者我要写书评

暂无评论

景观设计学（中英文） 2020年第2期8卷 110-121页

作者：黄伊伟美国加利福尼亚大学戴维斯分校人类生态学系

在"儿童友好型城市倡议"发起20余载后,中国景观设计行业的相关实践进展依然较为缓慢,建成的儿童活动空间与儿童友好型城市的愿景仍存在一定差距。本文指出,导致这一问题的原因包括:1)儿童作为这些项目的核心使用者,未能充分参与设计过程... 详细信息

在"儿童友好型城市倡议"发起20余载后,中国景观设计行业的相关实践进展依然较为缓慢,建成的儿童活动空间与儿童友好型城市的愿景仍存在一定差距。本文指出,导致这一问题的原因包括:1)儿童作为这些项目的核心使用者,未能充分参与设计过程,致使其真实需求并未反映在设计方案中;2)目前的城市儿童景观设计主要围绕独立项目进行设计定位和概念提炼,缺乏从文化和社会层面对整个城市儿童活动空间系统及其对儿童产生的影响进行综合考量。对此,本文提出,景观设计师可从生态系统理论和公众参与理论中获得启发,积极拓展自身在未来儿童友好型城市营造中的职责。最后,本文通过介绍美国"成长在博尔德"计划、英国伦敦的"游乐和非正式娱乐"策略,以及美国绿色校园三个国际案例,阐明景观设计师在儿童友好型城市的建设中不仅仅是设计策略的制定者,亦可充当利益相关方的协调者和参与式设计项目的发起者;景观设计师的工作也不应限于传统的儿童游乐空间设计,而应更加关注社区和整个城市的空间格局,以推动整个社会对儿童权利的重视,最终完成城市空间的串联、整合与整体提升。

关键词：儿童友好型城市城市空间生态系统理论公众参与参与式设计景观设计社会职责

血清irisin在急性缺血性脑卒中患者预后评估中的临床价值

在线全文

学校读者我要写书评

暂无评论

中国全科医学 2019年第A1期22卷 85-88页

作者：黄一伟浙江省诸暨市人民医院神经内科

目的探讨血清鸢尾素(irisin)在急性缺血性脑卒中患者预后评估中的临床价值。方法选择2016年5月—2018年5月在浙江省诸暨市人民医院收治的183例急性缺血性脑卒中患者作为观察组,并根据患者出院3个月随访mRS评分将患者分为预后良好组110例... 详细信息

目的探讨血清鸢尾素(irisin)在急性缺血性脑卒中患者预后评估中的临床价值。方法选择2016年5月—2018年5月在浙江省诸暨市人民医院收治的183例急性缺血性脑卒中患者作为观察组,并根据患者出院3个月随访mRS评分将患者分为预后良好组110例(mRS评分0~2)与预后不良组73例(mRS评分3~5),同时选择同期健康体检人群88例作为对照组。并采用酶联免疫吸附法(ELISA)检测患者血清irisin水平。比较各组血清irisin水平的关系,并通过研究对象工作特征曲线(ROC)和曲线下面积(AUC)评价血清irisin在急性缺血性脑卒中患者预后评估中的临床作用,对影响患者预后因素采用Logistic回归分析。结果两组年龄、高血脂比较明显有差异,且预后良好组NIHSS评分、血清irisin水平均明显低于预后不良组(P0.05);经ROC曲线分析结果显示:血清irisin曲线下面积为0.833(95%CI:0.745~0.923),截断值为320 ng/ml,灵敏度以及特异性分别为76.4%、72.1%;采用Logistic回归分析,血清irisin﹥230 ng/L(OR=3.08,95%CI:2.53~3.75)、年龄>60岁(OR=3.49,95%CI:2.30~5.31)、有高血脂症(OR=2.45,95%CI:1.91~3.15)、NIHSS评分>7分(OR=5.31,95%CI:3.21~8.78)为急性缺血性脑卒中患者预后良好的危险因素。结论血清irisin水平在急性缺血性脑卒中患者中降低,并在不预后不良患者中降至更低,能够作为急性缺血性脑卒中患者预后评估中的标志物,对于判断患者的预后有着重要的临床意义。

关键词：鸢尾素急性缺血性脑卒中预后

光催化还原杂环化共价有机框架构筑富电子吸附剂实现碘的理想吸附

在线全文

学校读者我要写书评

暂无评论

Science China Materials 2023年第6期66卷 2339-2345页

作者：黄易伟喻志武张晴云罗峰 School of Chemistry Biology and Materials ScienceEast China University of TechnologyNanchang 330013China High Magnetic Field Laboratory Chinese Academy of SciencesHefei 230031China

碘的理想吸附剂通常需要具有两个特征,即高的吸附容量和快的吸附速率,但是这项课题仍然富有挑战性.本文通过构筑杂环化共价有机框架,阐述了一种有效构筑理想碘吸附剂的方法.这种杂环化基于一种后修饰的方式,采用了一种原位光催化双键与... 详细信息

碘的理想吸附剂通常需要具有两个特征,即高的吸附容量和快的吸附速率,但是这项课题仍然富有挑战性.本文通过构筑杂环化共价有机框架,阐述了一种有效构筑理想碘吸附剂的方法.这种杂环化基于一种后修饰的方式,采用了一种原位光催化双键与邻氨基苯甲酰胺成环的技术.基于该方法得到的材料ECUT-COF-13具有高的碘吸附容量(10.81 g g^(-1),高于所有报道的碘吸附材料)和吸附速率(1.4 g h^(-1),高于所有报导的二维共价有机框架材料).该材料优异的碘吸附性能是基于一种富电子机理,这种富电子状态主要来源于光催化还原杂环化共价有机框架(同时提高了网格的共轭性和氮含量).该研究成果不仅提供了一种构筑功能共价有机框架的新路径,同时提供了一种构筑富电子共价有机框架结构的通用策略.

关键词：邻氨基苯甲酰胺共轭性光催化还原电子状态吸附速率共价有机框架材料碘吸附吸附容量