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响应面法优化无糖型苦瓜番茄凝胶糖果配方

粮食与食品工业 2024年第4期31卷 32-38页

作者：刘莹娟李菁刘明昕慈慧尹显婷通化师范学院食品科学与工程学院通化134002 通化市产品质量检验所通化134000

本试验使用番茄、苦瓜、赤藓糖醇和明胶作为主要成分,通过单因素试验和响应面试验并以感官评分为指标优化无糖型苦瓜番茄凝胶糖果的生产工艺。结果表明:当番茄汁添加量为35.5%,苦瓜汁添加量为6%,赤藓糖醇添加量为24%,明胶添加量为12%时... 详细信息

本试验使用番茄、苦瓜、赤藓糖醇和明胶作为主要成分,通过单因素试验和响应面试验并以感官评分为指标优化无糖型苦瓜番茄凝胶糖果的生产工艺。结果表明:当番茄汁添加量为35.5%,苦瓜汁添加量为6%,赤藓糖醇添加量为24%,明胶添加量为12%时所制得的凝胶糖果在感官评价上获得最高分。以此工艺制备的凝胶糖果外形美观,有嚼劲,弹性较好,富有独特的苦瓜及番茄风味。并结合质构特性分析,得出制备的凝胶糖果硬度、胶着性、咀嚼性、粘性均小于市售同类型凝胶糖果。

关键词：番茄苦瓜凝胶糖果配方优化

Atrial Septal Defect(ASD)associated long non-coding RNA STX18-AS1 maintains time-course of in vitro cardiomyocyte differentiation

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Genes & Diseases 2023年第4期10卷 1150-1153页

作者： yingjuan liu Mun-kit Choy Sabu Abraham Gennadiy Tenin Graeme C.Black Bernard D.Keavney Division of Cardiovascular Sciences University of ManchesterManchester M139PLUK Manchester University NHS Foundation Trust Manchester Academic Health Science CentreManchester M139NQUK Division of Evolution&Genomic Sciences University of ManchesterManchester M139WLUK

Congenital heart disease(CHD)is the commonest birth defect,affecting approximately 9.4/1000 live births.^(1)Atrial Septal Defect(ASD)is one of the commonest CHD clinical phenotypes,which frequently requires treatment either in childhood or adulthood,and can lead to severe complications such as right heart failure and cardiac *** genome-wide association studies(GWAS)have identified a region of chromosome 4p16(Ch4p16)associated with the risk of ASD.

关键词： clinical maintain cardiac

Nitrogen incorporated oxygen vacancy enriched MnCo_(2)O_(x)/BiVO_(4) photoanodes for efficient and stable photoelectrochemical water splitting

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Nano Research 2024年第3期17卷 1140-1150页

作者： Liangcheng Xu yingjuan Zhang Boyan liu Xin Wang Gangqiang Zhu Lianzhou Wang Songcan Wang Wei Huang Frontiers Science Center for Flexible Electronics Xi’an Institute of Flexible Electronics(IFE)Northwestern Polytechnical University127 West Youyi RoadXi’an 710072China School of Physics and Information Technology Shaanxi Normal UniversityXi’an 710062China Nanomaterials Centre Australian Institute for Bioengineering and Nanotechnology and School of Chemical EngineeringThe University of QueenslandBrisbaneQueensland 4072Australia Research&Development Institute of Northwestern Polytechnical University in Shenzhen Sanhang Science&Technology BuildingNo.45thGaoxin South 9th RoadNanshan DistrictShenzhen 518063China

Oxygen vacancies in oxygen evolution cocatalysts(OECs)can significantly improve the photoelectrochemical(PEC)water splitting performance of ***,OECs with abundant oxygen vacancies have a poor stability when exposing to the highly-oxidizing photogenerated ***,we partly fill oxygen vacancies in a MnCo_(2)O_(x) OEC with N atoms by a combined electrodeposition and sol-gel method,which dramatically improves both photocurrent density and stability of a BiVO_(4) *** optimized N filled oxygen vacancy-rich MnCo_(2)O_(x)/BiVO_(4) photoanode(3 at.%of N)exhibits an outstanding photocurrent density of 6.5 mA·cm^(-2) at 1.23 VRHE under AM 1.5 G illumination(100 mW·cm^(-2)),and an excellent stability of over 150 *** characterizations and theoretical calculations demonstrate that N atoms stabilize the defect structure and modulate the surface electron distribution,which significantly enhances the stability and further increases the photocurrent ***,other heteroatoms such as carbon,phosphorus,and sulfur are confirmed to have similar effects on improving PEC water splitting performance of photoanodes.

关键词： water splitting oxygen evolution bismuth vanadate(BiVO_(4)) filling oxygen vacancies cocatalysts

Vomeronasal organ lesion disrupts social odor recognition, behaviors and fitness in golden hamsters

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Integrative Zoology 2014年第3期9卷 255-264页

作者： yingjuan liu Jinhua ZHANG Dingzhen liu Jianxu ZHANG State Key Laboratory of Integrated Management of Pest Insects and Rodents in Agriculture Institute of ZoologyChinese Academy of SciencesBeijingChina Ministry of Education Key Laboratory of Biodiversity Science and Ecological EngineeringInstitute of EcologyBeijing Normal UniversityBeijingChina

Most studies support the viewpoint that the vomeronasal organ has a profound effect on conspecific odor recognition,scent marking and mating behavior in the golden hamster(Mesocricetus auratus).However,the role of the vomeronasal organ in social odor recognition,social interaction and fitness is not well ***fore,we conducted a series of behavioral and physiological tests to examine the referred points in golden ham*** found that male hamsters with vomeronasal organ lesion showed no preference between a predator odor(the anal gland secretion of the Siberian weasels(Mustela sibirica)and putative female pheromone components(myristic acid and palmitic acid),but were still able to discriminate between these 2 kinds of *** behavioral tests of anxiety,we found that vomeronasal organ removal causes female hamsters to spend much less time in center grids and to cross fewer center grids and males to make fewer crossings between light and dark boxes than sham-operated *** indicates that a chronic vomeronasal organ lesion induced anxious responses in *** aggressive behavioral tests,we found that a chronic vomeronasal organ lesion decreased agonistic behavior in female hamsters but not in *** pup growth and litter size show no differences between the 2 *** together,our data suggested that vomeronasal organ ablation disrupted the olfactory recognition of social chemosignals in males,and induced anxiety-like and aggressive behavior changes in ***,a vomeronasal organ lesion did not affect the reproductive capacity and fitness of *** studies may have important implications concerning the role of the vomeronasal organ in golden hamsters and also in rodents.

关键词： anxious response golden hamster pheromone physiology vomeronasal organ

深入理解“思想政治工作是学校各项工作的生命线”的三重维度

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思想理论教育 2022年第5期 66-71页

作者：刘英娟东北师范大学马克思主义学部吉林长春130024

“思想政治工作是学校各项工作的生命线”这一重要论断内涵丰富,需要从历史的厚度、理论的深度与实践的力度来深刻揭示。从历史维度阐释中国共产党思想政治工作生命线理论的概念演进,具有其客观必然性;从理论维度探索中国社会主义学校... 详细信息

“思想政治工作是学校各项工作的生命线”这一重要论断内涵丰富,需要从历史的厚度、理论的深度与实践的力度来深刻揭示。从历史维度阐释中国共产党思想政治工作生命线理论的概念演进,具有其客观必然性;从理论维度探索中国社会主义学校教育理论的守正创新,具有其思想引领性;从现实维度推进新时代中国特色社会主义学校立德树人路径的继续拓展,具有其现实紧迫性。对这一论断的深入分析,有助于全面构建高质量思想政治工作体系,为新时代进一步落实立德树人根本任务提供理论遵循和现实启示。

关键词：思想政治工作生命线立德育人

Separation and Anti-Hantaan Virus Activity of Extracts from Alternanthera philoxcroides in vitro and in vivo

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Wuhan University Journal of Natural Sciences 2007年第6期12卷 1143-1147页

作者： liu yingjuan YANG Zhanqiu DENG Haiying XIAO Hong QU Chunfeng State Key Laboratory of Virology/Institute of Medical Virology School of Medicine Wuhan University Wuhan 43007 l Hubei China

A water-soluble substance was extracted from the Chinese herb, Alternantheraphiloxcroides with hot water and alcohol. Aliquots of this initial extract were further fractionated by treatment with ether, ethyl acetate and alcohol respectively. The four extracts were assayed for anti-viral activity against three serum, Hantaan virus 114 （HV114）, HV435 and A9 strains. Results show that the four extracts are capable of inhibiting Hantaan virus propagation, of which extract No. 1 has the best efficiency. The three dosage of extract No. 1, which are used upon three Hantaan virus serum IC50, are 153, 157, 154 μg/mL. New-born mice were made to be infected with HV114 and then fed in vivo with extract No.l on the 3rd, 10th and 14th days after being infected by the virus. The treatment continued for 8 days with a dosage of 2.5 g/kg. Result shows that survival rates of mice were 75%, 50% and 0, respectively. The median time to death （MTDs） of the three groups were 37, 30, 23 days.

关键词： antiviral activity Alternanthera philoxcroides Hantaan virus cell culture animal experiment

Frequency Regulation of VSC-MTDC System with Offshore Wind Farms

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Journal of Modern Power Systems and Clean Energy 2024年第1期12卷 275-286页

作者： Haoyu liu Chongru liu North China Electric Power University Beijing 102206China

Frequency regulation of voltage source converter-based multi-terminal high-voltage direct current(VSC-MTDC)system with offshore wind farms enhances the frequency stability by compensating the power for a disturbed AC ***,it is difficult to reasonably allocate frequency-regulation resources due to a lack of coordination mechanisms between wind farms and the MTDC ***,it is difficult for the frequency control of the wind farms to manage changes in wind speed;and the risk of wind-turbine stalls is ***,based on the kinetic energy of wind turbines and the power margin of the converters,the frequency-regulation capability of wind turbines is evaluated,and a dynamic frequency-support scheme considering the real-time frequency-support capability of the wind turbines and system frequency evolution is proposed to improve the frequency-support performance.A power adaptation technique at variable wind speeds is developed;the active power in the frequency-support stage and restoration stage is switched according to the wind speed.A hierarchical zoning frequency-regulation scheme is designed to use the frequency-regulation resources of different links in the MTDC system with wind *** simulation results show that the novel frequency-regulation strategy maintains frequency stability with wind-speed changes and avoids multiple frequency dips.

关键词： Wind generation voltage source converter-based multi-terminal high-voltage direct current(VSC-MTDC) frequency regulation cooperative control adaptive control variable wind speed

A Novel Design of a Pre-separation Panel Structure to Protect Against the Impact of an Explosion in an Aircraft Plenum Chamber

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Acta Mechanica Solida Sinica 2024年第1期37卷 166-180页

作者： Zongxing liu Xiang Yang Jun liu School of Aeronautics Northwestern Polytechnical UniversityXi'an 710072China COMAC Shanghai Aircraft Design and Research Institute Shanghai 201210China

To reduce the damage of the pressurizing panel structure of a fuselage caused by an explosion at the“least risk bomb location”in an aircraft structure,a new pre-separation panel structure was designed to resist blast ***,the dynamic strain response and morphology of impact damage of the new pre-separation panel were measured in an impact damage ***,the commercial software LS-DYNA was used to calculate the propagation of the blast shock wave,and the results were compared with empirical equations to verify the rationality of the numerical calculation ***,the fluid–structure coupling method was used to calculate the damage process of the pre-separation panel structure under the impact of an explosion wave and an impact *** calculated results were in good agreement with the test results,which showed the rationality of the calculation method and the *** residual strength of the damaged pre-separation panel was significantly higher than that of the original damaged *** results show that the new pre-separation panel structure is reasonable and has certain significance for guiding the design of plenum chambers with strong resistance to implosion for aircraft fuselages.

关键词： Pre-separation panel structure Explosive response Residual strength Aircraft plenum chamber Least risk bomb location

Effectiveness and safety of acupuncture in treatment of pregnancyrelated symptoms:a systematic review and Meta-analysis

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Journal of Traditional Chinese Medicine 2024年第1期44卷 16-26页

作者： liu Tingting liu Tongou liu Mingfu School of Traditional Chinese Medicine Clinical Medicine Hubei University of Traditional Chinese MedicineWuhan 430000China First Clinical College of Hubei University of Traditional Chinese Medicine Wuhan 430000China Department of Acupuncture and Tuina Affiliated Hospital of Hubei University of Traditional Chinese MedicineHubei Provincial Hospital of Traditional Chinese MedicineWuhan 430000China

OBJECTIVE:To systematically evaluate the efficacy and safety of acupuncture(AM)in the treatment of pregnancyrelated symptoms such as acute vomiting during ***:We comprehensively searched the available literature up to November 2021,including Pub Med,Embase,Cochrane Library,Chinese Biomedical Literature Database,and China National Knowledge Infrastructure Database,for randomized controlled trials(RCTs)on AM for the treatment of severe vomiting,insomnia,pharyngeal and pelvic pain,mood abnormalities,and dyspepsia during ***:Sixteen RCTs with a cumulative sample size of 1178 cases were *** these,964 patients were included in the *** Meta-analysis results showed that AM was more efficient than Western medicine in treating discomfort during pregnancy[odds ratio(OR)=1.19,95%confidence interval(CI)(1.11,1.28),P<0.01].AM was better than the control group in improving the visual analog scale scores[standard mean difference(SMD)=0.62,95%CI(0.53,0.71),P<0.01].AM was superior to the control group in improving Numerical Rating Scale(NRS)symptom scores[OR=7.31,95%CI(3.36,15.94),P<0.01].There was no significant difference in adverse effects between the AM and sham-AM groups and the analgesic drug group[OR=0.70,95%CI(0.39,1.28),P=0.25],but the treatment and control groups had mild adverse effects with a low ***:AM is more effective than other treatments or pharmacotherapy alone in the treatment of pregnancy-related symptoms,and is relatively ***,the quality of the included trials was rather poor,and high-quality studies are required to confirm our findings.

关键词： acupuncture pregnancy nausea vomiting sleep initiation and maintenance disorders low back pain pelvic pain mood abnormalities Meta-analysis systematic review