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Distribution, burial fluxes and carbon sink effect of sedimentary organic carbon in the eastern China seas

Science China Earth Sciences 2024年第10期67卷 3062-3082页

作者： Xuefa SHI bin WU Shuqing QIAO Zhengquan YAO Limin hu Yazhi BAI Shan hu Jie SHENG Yanguang LIU Shengfa LIU Kunshan WANG Jianjun ZOU Key Laboratory of Marine Geology and Metallogeny First Institute of OceanographyMinistry of Natural ResourcesQingdao 266061China Laboratory for Marine Geology Qingdao Marine Science and Technology CenterQingdao 266237China Key Laboratory of Deep Sea Mineral Resources Development Shandong Province(Preparatory)Qingdao 266061China Key Laboratory of Submarine Geosciences and Technology College of Marine GeosciencesOcean University of ChinaQingdao 266100China

The ocean is the largest active carbon reservoir on Earth. Organic carbon(OC), as the primary species of carbon sequestration in the ocean, plays an important role in the global carbon cycle through its deposition and burial. In this study,sedimentary OC data from 5796 stations, together with relevant geochemical and sedimentological parameters in the Bohai Sea,Yellow Sea, and East China Sea(BYES) were used to summarize and elucidate the distribution and burial patterns of sedimentary OC, and assess carbon sink effect of sedimentary OC burial. The results show that the OC content in the sediments of the BYES ranges from 0.00% to 2.12%, with an average content of 0.47%±0.26%. OC content is significantly correlated with finegrained sediments, with an average OC content in mud areas being 39% higher than that in non-mud areas. Modern OC buried in the BYES are mainly deposited in 7 major mud areas, with a total sedimentary OC burial flux of approximately 8.20 Mt C yr^(–1).Among them, the burial flux of biospheric OC is 6.92 Mt C yr^(–1), equivalent to the OC consumption amount of silicate weathering of the 9 major river basins in the eastern China. In its natural state, the annually sequestered OC in the sediments of the eastern China seas is equivalent to 25.37 Mt of atmospheric CO_(2), indicating a significant carbon sink effect. The distribution and burial of terrigenous OC in the BYES are mainly influenced by the large river inputs and complex marine hydrodynamic environment,while human activities such as dam construction have significantly altered the OC burial in these coastal mud areas.

关键词： Sedimentary organic carbon Burial flux Carbon sink effect Carbon cycle Eastern China seas

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Genus-specific secondary metabolome in Allokutzneria and Kibdelosporangium

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Synthetic and Systems Biotechnology 2024年第3期9卷 381-390页

作者： Man-Jing Ma Wen-Chao Yu huai-ying Sun bing-Cheng Dong Gang-Ao hu Zhen-Yi Zhou Yi hua Buddha Bahadur Basnet Yan-Lei Yu Hong Wang bin Wei College of Pharmaceutical Science&Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals Zhejiang Key Laboratory of GreenLow-Carbonand Efficient Development of Marine Fishery ResourcesZhejiang University of TechnologyHangzhou 310014China Central Department of Biotechnology Trihuvan UniversityKathmanduNepal

Rare actinomycete genera are highly recognized as a promising source of structurally diverse and bioactive natural *** these genera,Allokutzneria and Kibdelosporangium are two phylogenetically closely related and have been reported to encode some valuable biosynthetic enzymes and secondary ***,there is currently no relevant systematic research available to outline the linkage of genomic and metabolomics for specific secondary metabolites in these two promising *** this study,we first investi-gated the genus-specific secondary metabolic potential in Allokutzneria and Kibdelosporangium by comparing the diversity and novelty of their secondary metabolite biosynthetic gene clusters(BGCs).The specific secondary metabolites produced by two representative strains of these genera were comprehensively investigated using untargeted metabolomics *** findings unveiled that the majority(95.4%)of the gene cluster families(GCFs)encoded by Allokutzneria and Kibdelosporangium were genus-specific,including NRPS GCFs encoding *** untargeted metabolomics analysis revealed that the metabolic profiles of two representative strains exhibit extensive specificity,with the culture medium having a big impact on the metabolic ***,an MS-cluster featuring a series of hydroxamate-type siderophores was identified from Allokutzneria albata JCM 9917,with two of them,including a novel one(N-deoxy arthrobactin A),being experimentally *** present study offers valuable insights for the targeted discovery of genus-specific natural products from microorganisms.

关键词： Genus-specific secondary metabolism Allokutzneria Kibdelosporangium Genome mining Untargeted metabolomics Siderophore

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Mitogenome-based phylogeny of mosquitoes(Diptera:Culicidae)

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Insect Science 2024年第2期31卷 599-612页

作者： De-Hong Chen Shu-Lin He Wen-Bo Fu Zhen-Tian Yan Yun-Jian hu huan Yuan Ming-bin Wang bin Chen Chongqing Key Laboratory of Vector Insects Institute of Entomology and Molecular BiologyChongqing Normal UniversityChongqingChina

Mosquitoes are of great medical significance as vectors of many deadly *** have been widely used in phylogenetic studies,but mitogenome knowledge within the family Culicidae is limited,and Culicidae phylogeny is far from *** this study,we surveyed the mitogenomes of 149 Culicidae species,including 7 newly sequenced *** analysis of 149 mosquito mitogenomes shows gene composition and order to be identical to that of an ancestral insect,and the AT bias,length variation,and codon usage are all consistent with that of other reported Dipteran *** analyses based on the DNA sequences of the 13 protein-coding genes from the 149 species robustly support the monophyly of the subfamily Anophelinae and the tribes Aedini,Culicini,Mansonini,Sabethini,and *** resolve ambiguous relationships between clades within the subfamily Culicinae,we performed topological tests and show that Aedini is a sister to Culicini and that Uranotaenini is a sister to(Mansonini)+(Toxorhynchitini+Sabethini).In addition,we estimated divergence times using a Bayesian relaxation clock based on the sequence data and 3 fossil calibration *** results show mosquitoes diverged during the Early Jurassic with massive Culicinae radiations during the Cretaceous,coincident with the emergence of angiosperms and the burst of mammals and ***,this study,which uses the largest number of Culicidae mitogenomes sequenced to date,comprehensively reveals the mitogenome characteristics and mitogenome-based phylogeny and divergence times of Culicidae,providing information for further studies on the mitogenome,phylogeny,evolution,and taxonomic revision of Culicidae.

关键词： characterization Culicidae evolution mitogenomes mosquitoes phylogeny

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circRNAs deregulation in exosomes derived from BEAS-2B cells is associated with vascular stiffness induced by PM_(2.5)

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Journal of Environmental Sciences 2024年第3期137卷 527-539页

作者： Qingping Liu Yaling Zhang bin Han Mengruo Wang huaifang hu Jie Ning Wentao hu Meiyu Chen Yaxian Pang Yuanyuan Chen Lei Bao Yujie Niu Rong Zhang Department of Toxicology Hebei Medical UniversityShijiazhuang 050017China State Key Laboratory of Environment Health(Incubation) Key Laboratory of Environment and HealthMinistry of EducationKey Laboratory of Environment and Health(Wuhan)Ministry of Environmental ProtectionSchool of Public HealthTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China China CDC Key Laboratory of Environment and Population Health National Institute of Environmental HealthChinese Center for Disease Control and PreventionBeijing 100021China Occupational Health and Environmental Health Hebei Medical UniversityShijiazhuang 050017China Hebei Key Laboratory of Environment and human Health Hebei Medical UniversityShijiazhuang 050017China

As an environmental pollutant,ambient fine particulate matter (PM_(2.5)) was linked to cardiovascular *** molecular mechanisms underlying PM_(2.5)-induced extrapulmonary disease has not been elucidated *** this study the ambient PM_(2.5)exposure mice model we established was to explore adverse effects of vessel and potential ***-term PM_(2.5)exposure caused reduced lung function and vascular stiffness in *** chronic PM_(2.5)induced migration and epithelial-mesenchymal transition (EMT) phenotype in BEAS-2B *** PM_(2.5)treatment,the circRNAs and mRNAs levels of exosomes released by BEAS-2B cells were detected by competing endogenous RNA (ceRNA) array,which contained 1664 differentially expressed circRNAs (DE-circRNAs) and 308 differentially expressed m RNAs (DE-mRNAs).By bioinformatics analysis on host genes of DE-circRNAs,vascular diseases and some pathways related to vascular diseases including focal adhesion,tight junction and adherens junction were ***,ceRNA network was constructed,and DE-mRNAs in ceRNA network were conducted functional enrichment analysis by Ingenuity Pathway Analysis,which indicated that hsa_circ_0012627,hsa_circ_0053261and hsa_circ_0052810 were related to vascular endothelial ***,it was verified experimentally that Exo^(PM2.5)could induce endothelial dysfunction by increased endothelial permeability and decreased relaxation in *** present study,we investigated in-depth knowledge into the molecule events related to PM_(2.5) toxicity and pathogenesis of vascular diseases.

关键词： Fine particulate matter Vascular stiffness Exosome ceRNA microarray Endothelial dysfunction

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Transfer force perception skills to robot‐assisted laminectomy via imitation learning from human demonstrations

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CAAI Transactions on Intelligence Technology 2024年第4期9卷 903-916页

作者： Meng Li Xiaozhi Qi Xiaoguang Han ying hu bing Li Yu Zhao Jianwei Zhang Harbin Institute of Technology ShenzhenChina Shenzhen Institute of Advanced Technology Chinese Academy of SciencesShenzhenChina Shenzhen Key Laboratory of Minimally Invasive Surgical Robotics and System Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhenChina Beijing Jishuitan Hospital Capital Medical UniversityBeijingChina Department of Orthopedics Peking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina University of Hamburg Hamburg22527Germany

A comparative study of two force perception skill learning approaches for robot‐assisted spinal surgery,the impedance model method and the imitation learning(IL)method,is *** impedance model method develops separate models for the surgeon and patient,incorporating spring‐damper and bone‐grinding *** surgeons'feature parameters are collected and mapped using support vector regression and image navi-gation *** imitation learning approach utilises long short‐term memory networks(LSTM)and addresses accurate data labelling challenges with custom *** results demonstrate skill recognition rates of 63.61%-74.62%for the impedance model approach,relying on manual feature ***,the imitation learning approach achieves a force perception recognition rate of 91.06%,outperforming the impedance model on curved bone *** findings demonstrate the potential of imitation learning to enhance skill acquisition in robot‐assisted spinal surgery by eliminating the laborious process of manual feature extraction.

关键词： learning(artificial intelligence) medical applications medical signal processing robotics

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Instrumented oscillographic study on impact toughness of an axle steel DZ2 with different tempering temperatures

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International Journal of Minerals,Metallurgy and Materials 2024年第7期31卷 1590-1598页

作者： Shuo Liu Peng Zhang bin Wang Kaizhong Wang Zikuan Xu Fangzhong hu Xin Bai Qiqiang Duan Zhefeng Zhang Shi-changxu Innovation Center for Advanced Materials Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China School of Materials Science and Engineering University of Science and Technology of ChinaShenyang 110016China Technology Center Ma'anshan Iron and Steel Co.Ltd.Ma'anshan 243000China

Compared with the conventional Charpy impact test method,the oscillographic impact test can help in the behavioral analysis of materials during the fracture *** this study,the trade-off relationship between the strength and toughness of a DZ2 axle steel at various tempering temperatures and the cause of the improvement in impact toughness was *** tempering process dramatically influenced carbide precipitation behavior,which resulted in different aspect ratios of *** toughness improved along with the rise in tempering temperature mainly due to the increase in energy required in impact crack *** characteristics of the impact crack propagation process were studied through a comprehensive analysis of stress distribution,oscilloscopic impact statistics,fracture morphology,and carbide *** poor impact toughness of low-tempering-temperature specimens was attributed to the increased number of stress concentration points caused by carbide morphology in the small plastic zone during the propagation process,which resulted in a mixed distribution of brittle and ductile fractures on the fracture surface.

关键词： axle steel DZ2 tempering process impact toughness oscillographic impact test impact crack propagation carbides

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Dielectric and energy storage properties of PbO–SrO–Nb_(2)O_(5)–Na_(2)O–Si thin films by annealing

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Rare Metals 2024年第1期43卷 351-355页

作者： Fei-hu Tan Qing-Meng Zhang Feng Wei Hong-bin Zhao Xiao Zhang Jun Du State Key Laboratory of Advanced Materials for Smart Sensing General Research Institute for Nonferrous MetalsBeijing 100088China Advanced Electronic Materials Institute General Research Institute for Nonferrous MetalsBeijing 100088China

Dielectric and energy storage properties of PbOSrO-Na_(2)O-Nb_(2)O_(5)-SiO_(2)(PSNNS) thin films with annealing temperature from 700 to 850 ℃ were investigated by measuring their capacitance-electric filed curve and hysteresis *** results show that the highest dielectric constant and energy density are 81.2 and 17.0 J·cm^(-3),respectively,which is obtained in the sample with annealing temperature of 800 ℃.Annealed from 700 to800 ℃,the dielectric constant and energy storage performance of PSNNS films are continuously ***,with annealing temperature up to 850 ℃,their dielectric constant decreases,which might be related with the removal of interfacial defects as a function of annealing *** is one of the causes of space charge phenomenon,resulting in the increase in dielectric ***,the micro structure analysis by X-ray diffraction(XRD) and transmission electron microscope(TEM) indicates that the change of crystallization phase and interfacial polarization takes responsibility to the results.

关键词： Thin film Pulse laser deposition Annealing temperature Energy storage density

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Nano-frictional mechano-reinforcing porous nanowires scaffolds

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Friction 2024年第5期12卷 968-980页

作者： Licheng huA Conghu hu Jingkang ZHANG Jin LI Chenjie GU bin huANG Guangyong LI Jianke DU Wanlin GUO Smart Materials and Advanced Structures Laboratory School of Mechanical Engineering&MechanicsNingbo UniversityNingbo315211China Key Laboratory for Intelligent Nano Materials and Devices of Ministry of Education Nanjing University of Aeronautics and AstronauticsNanjing210016China Key Laboratory of Impact and Safety Engineering Ministry of EducationSchool of mechanical Engineering and MechanicsNingbo UniversityNingbo315211China Department of Microelectronics and Engineering Ningbo UniversityNingbo315211China

Artificial biomaterials with dynamic mechano-responsive behaviors similar to those of biological tissues have been drawing great *** this study,we report a TiO_(2)-based nanowire(TiO_(2)NWs)scaffolds,which exhibit dynamic mechano-responsive behaviors varying with the number and amplitude of nano-deformation *** is found that the elastic and adhesive forces in the TiO_(2)NWs scaffolds can increase significantly after multiple cycles of *** nanofriction experiments show the triboelectric effect of increasing elastic and adhesive forces during the nano-deformation cycles of TiO_(2)NWs *** properties allow the TiO_(2)NW scaffolds to be designed and applied as intelligent artificial biomaterials to simulate biological tissues in the future.

关键词： TiO_(2)NWs scaffolds nano-deformation mechano-reinforcing triboelectric effect intelligent artificial biomaterials

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A Sustainable Strategy for Spent Cathode Carbon Blocks Hazardous Waste Recycling Using binary Molten Salt Thermal Treatment

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Journal of Thermal Science 2024年第3期33卷 1082-1093页

作者： LI bin DING Yan JIAO Yuyong XU Fang WANG Xinyang ZHENG Fei ZOU Junpeng GAO Qiang hu Hongyun Faculty of Engineering China University of GeosciencesWuhan430074China Institute for Natural Disaster Risk Prevention and Emergency Management China University of GeosciencesWuhan430074China State Key Laboratory of Coal Combustion Huazhong University of Science and TechnologyWuhan430074China

Waste-to-Energy treatment is a promising path to environment and energy management in the *** work detailed a binary molten salt thermal treatment methodology for the detoxification of spent cathode carbon block(SCCB)waste and the recycling of carbonaceous *** thermal behavior of SCCB and SCCB blended with molten salts was *** was found that the NaCl-Na_(2)CO_(3)binary molten salts significantly contributed to reducing pyrolysis onset temperature by 334.3 K compared to that of SCCB itself(i.e.,activation energy of pyrolysis reaction was reduced from 4.24×10^(5)to 2.30×10^(5)J/mol),thus helping to lower thermal treatment energy *** the addition of binary molten salts,the residue after thermal treatment in a horizontal tube furnace experiment was separated into two *** bottom-layer residue was mainly composed of molten *** fluorine content in the form of NaF and CaF_(2)of top-layer residue was reduced significantly while the carbon content remained ***,the leaching concentration of fluoride ion was decreased from 4620 mg/L to 856 mg/*** is noted that the NaF and CaF_(2)can be removed through water-leaching and hydrothermal acid-leaching methods and thus the carbonaceous materials with a calorific value of 17.5 MJ/kg were obtained.

关键词： spent cathode carbon block hazardous solid waste detoxification binary-molten-salt thermal treatment carbon recycling pyrolysis kinetics

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LncRNA HOTAIR promotes DNA damage repair and radioresistance by targeting ATR in colorectal cancer

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Oncology Research 2024年第8期32卷 1335-1346页

作者： HAIQING hu HAO YANG ShuAIShuAI FAN XUE JIA ying ZHAO HONGRUI LI Department of Endoscopic Center Peking University Cancer Hospital(Inner Mongolia Campus)&Affiliated Cancer Hospital of Inner Mongolia Medical UniversityHuhhot010020China Department of Radiation Oncology Peking University Cancer Hospital(Inner Mongolia Campus)&Affiliated Cancer Hospital of Inner Mongolia Medical UniversityKey Laboratory of Radiation Physics and Biology of Inner Mongolia Medical UniversityPeking University Cancer Hospital(Inner Mongolia Campus)&Affiliated Cancer Hospital of Inner Mongolia Medical UniversityHuhhot010020China Graduate School Inner Mongolia Medical UniversityHuhhot010020China

Long non-coding RNAs(lncRNAs)have been implicated in cancer progression and drug resistance ***,there is evidence that lncRNA HOX transcript antisense intergenic RNA(HOTAIR)is involved in colorectal cancer(CRC)*** present study aimed to examine the functional role of lncRNA HOTAIR in conferring radiotherapy resistance in CRC cells,as well as the underlying *** relative expression levels of HOTAIR were examined in 70 pairs of CRC tumor and para-cancerous tissues,as well as in radiosensitive and radioresistant *** correlations between HOTAIR expression levels and clinical features of patients with CRC were assessed using the Chi-square *** assays such as cell proliferation,colony formation and apoptosis assays were conducted to determine the radiosensitivity in CRC cells with HOTAIR silencing after treatment with different doses of *** pull-down assay andﬂuorescence in situ hybridization(FISH)were used to determine the interaction between HOTAIR and DNA damage response mediator ataxia-telangiectasia mutated-and Rad3-related(ATR).HOTAIR was signiﬁcantly upregulated in CRC tumor tissues,especially in radioresistant tumor *** elevated expression of HOTAIR was correlated with more advanced histological grades,distance metastasis and the poor prognosis in patients with *** HOTAIR suppressed the proliferation and promoted apoptosis and radiosensitivity in CRC *** knockdown also inhibited the tumorigenesis of CRC cells and enhanced the sensitivity to radiotherapy in a mouse xenograft ***,the data showed that HOTAIR could interact with ATR to regulate the DNA damage repair signaling *** HOTAIR impaired the ATR-ATR interacting protein(ATRIP)complex and signaling in cell cycle ***,the present results indicate that lncRNA HOTAIR facilitates the DNA damage response pathway and promotes radioresistance in CRC cells by targeting ATR.

关键词： LncRNA HOTAIR CRC radioresistance DNA damage repair ATR

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