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Application of artificial intelligence-driven endoscopic screening and diagnosis of gastric cancer

World Journal of Gastroenterology 2021年第22期27卷 2979-2993页

作者： Yu-Jer Hsiao Yuan-Chih Wen Wei-Yi Lai Yi-ying Lin Yi-Ping Yang Yueh Chien Aliaksandr A Yarmishyn De-Kuang Hwang Tai-Chi Lin Yun-Chia Chang Ting-Yi Lin Kao-Jung Chang Shih-Hwa Chiou ying-chun jheng Department of Medical Research Taipei Veterans General HospitalTaipei 112201Taiwan School of Medicine National Yang-Ming Chiao Tung UniversityTaipei 112304Taiwan Department of Medical Education Taipei Veterans General HospitalTaipei 112201Taiwan Institute of Pharmacology National Yang-Ming Chiao Tung UniversityTaipei 112304Taiwan Department of Internal Medicine Taipei Veterans General HospitalTaipei 112201Taiwan Critical Center Taipei Veterans General HospitalTaipei 112201Taiwan Department of Ophthalmology Taipei Veterans General HospitalTaipei 112201Taiwan Institute of Clinical Medicine National Yang-Ming Chiao Tung UniversityTaipei 112201Taiwan Department of Medicine Kaohsiung Medical UniversityKaohsiung 80708Taiwan Institute of Clinical Medicine National Yang-Ming Chiao Tung UniversityTaipei 112304Taiwan Big Data Center Taipei Veterans General HospitalTaipei 112201Taiwan

The landscape of gastrointestinal endoscopy continues to evolve as new technologies and techniques become *** advent of image-enhanced and magnifying endoscopies has highlighted the step toward perfecting endoscopic screening and diagnosis of gastric ***,with the development of convolutional neural network,artificial intelligence(AI)has made unprecedented breakthroughs in medical imaging,including the ongoing trials of computer-aided detection of colorectal polyps and gastrointestinal *** the past demi-decade,applications of AI systems in gastric cancer have also *** AI’s efficient computational power and learning capacities,endoscopists can improve their diagnostic accuracies and avoid the missing or mischaracterization of gastric neoplastic *** far,several AI systems that incorporated both traditional and novel endoscopy technologies have been developed for various purposes,with most systems achieving an accuracy of more than 80%.However,their feasibility,effectiveness,and safety in clinical practice remain to be seen as there have been no clinical trials ***,AI-assisted endoscopies shed light on more accurate and sensitive ways for early detection,treatment guidance and prognosis prediction of gastric *** review summarizes the current status of various AI applications in gastric cancer and pinpoints directions for future research and clinical practice implementation from a clinical perspective.

关键词： Artificial intelligence Diagnostic Therapeutic Endoscopy Gastric cancer Gastritis

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Enhanced Biometric Score Fusion Scheme Based on the AdaBoost Algorithm

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Journal of Electronic Science and Technology 2017年第2期15卷 187-193页

作者： Wei-Yang Lin Chih-Yang Lin Chuan-jheng Yang Department of Computer Science and Information Engineering National Chung Cheng UniversityChiayi 62102 Department of Communications Engineering Yuan-Ze University Taoyuan 32003

Information fusion in biometric systems, either multimodal or intramodal fusion, usually provides an improvement in recognition performance. This paper presents an improved score-level fusion scheme called boosted score fusion. The proposed framework is a two-stage design where an existing fusion algorithm is adopted at the first stage. At the second stage, the weights obtained by the AdaBoost algorithm are utilized to boost the performance of the previously fused results. The experimental results demonstrate that the performance of several score-level fusion methods can be improved by using the presented method.

关键词： Index Terms-AdaBoost biometric authentication face recognition score-level fusion.

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Glucose detection in a highly scattering medium with diffuse photon-pair density wave

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Journal of Innovative Optical Health Sciences 2017年第1期10卷 53-58页

作者： Li-Ping Yu jheng-Syong Wu Sheng-Yi Chang Chien Chou Biomedical Engineering Research Center Chang Gung University Taoyuan 333Taiwan Graduate Institute of Electro-Optical Engineering Chang Gung University Taoyuan 333Taiwan Institute of Chemistry A cademic SinicaNankangTaipei 115Taiwan Ph.D Program of Biomedical Engineering Chang Gung University Taoyuan 333Taiwan Department of Mechanics Ming Chi University of Technology New Taipei 243Taiwan

We propose a novel optical method for glucose measurement based on difuse photon-pair density wave(DPPDW)in a multiple scattering medium(MSM)where the light scattering of photon-pair is induced by refractive index mismatch between scatters and phantom ***-mentally,the DPPDW propagates in MSM via a two frequency laser(TFL)beam wherein highly correlated pairs of linear polarized photons are *** reduced scattering coefficientμ2s and absorption coefficientμ2a of DPPDW are measured simultaneously in terms of the amplitude and phase measurements of the detected heterodyne signal under arrangement at different dis-tances between the source and detection fibers in *** results show that the sensitivity of glucose detection via glucose-induced change of reduced scattering coefficient(δμ′2)is 0.049%mM^(-1)in a 1%intralipid *** addition,the linear range ofδμ′2s vs glucose concentration implies that this DPPDW method can be used to monitor glucose concentration continuously and noninvasively subcutaneously.

关键词： Difuse photon-pair density wave glucose multiple scattering polarization gating spatial coherence gating.

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Difference Among Similarity:A Study on Macao Students’Adjustment Experiences in Taiwan’s Higher Education Systems

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ECNU Review of Education 2021年第4期4卷 764-787页

作者：陈志峰郑英杰 Macao Polytechnic Institute Center for Teacher Education Taiwan Sport UniversityNo.250Wenhua 1st Rd.GuishanTaoyuan 33301TaiwanChina

Purpose:This study focused on cross-region student mobility to explore whether Macao students have adjustment issues while studying and living in ***/Approach/Methods:A total of 663 Macao students were surveyed in Taiwan,and the statistical methods,including correlation,t-test,analysis of variance,and hierarchical regression analysis were addressed to analyze the ***:Macao students,even while studying in a Chinese context,did have social and psychological adjustment issues(i.e.,social support and self-efficacy).Originality/Value:This study could shed some light on understanding cross-region students as well as providing practical guides for relevant governmental departments in their policy regarding outbound students.

关键词： Adjustment cross-region student mobility Macao self-efficacy social support

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Cluster-Based Saliency-Guided Content-Aware Image Retargeting

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Journal of Electronic Science and Technology 2017年第2期15卷 141-146页

作者： Li-Wei Kang Ching-Yu Tseng Chao-Long jheng Ming-Fang Weng Chao-Yung Hsu Graduate School of Engineering Science and Technology and the Department of Computer Science and Information Engineering MPI Corporation Hsinchu Changing Information Technology Inc.Hsinchu 308 Institute for Information Industry Taipei 106 automation and Instrumentation System Development Sec. China Steel CorporationKaohsiung 81233

Straightforward image resizing operators without considering image contents （e.g., uniform scaling） cannot usually produce satisfactory results, while content-aware image retargeting aims to arbitrarily change image size while preserving visually prominent features. In this paper, a cluster-based saliency-guided seam carving algorithm for content- aware image retargeting is proposed. To cope with the main drawback of the original seam carving algorithm relying on only gradient-based image importance map, we integrate a gradient-based map and a cluster-based saliency map to generate a more reliable importance map, resulting in better single image retargeting results. Experimental results have demonstrated the efficacy of the proposed algorithm.

关键词： Index Terms--Content-aware image retargeting image resizing multimedia adaptation saliency detection seam carving.

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Differential DNA methylation analysis of SUMF2,ADAMTS5,and PXDN provides novel insights into colorectal cancer prognosis prediction in Taiwan

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World Journal of Gastroenterology 2022年第8期28卷 825-839页

作者： Jing-Quan Su Pin-Yu Lai Pei-Hsuan Hu Je-Ming Hu Pi-Kai Chang Chao-Yang Chen Jia-jheng Wu Yu-Jyun Lin Chien-An Sun Tsan Yang Chih-Hsiung Hsu Hua-Ching Lin Yu-Ching Chou School of Medicine National Defense Medical CenterTaipei 114TaiwanChina School of Public Health National Defense Medical CenterTaipei 114TaiwanChina Division of Colorectal Surgery Department of surgeryTri-Service General HospitalNational Defense Medical CenterTaipei 114TaiwanChina Graduate Institute of Medical Sciences National Defense Medical CenterTaipei 114TaiwanChina Department of Public Health College of MedicineFu-Jen Catholic UniversityNew Taipei City 242TaiwanChina Big Data Research Center College of MedicineFu-Jen Catholic UniversityNew Taipei City 242TaiwanChina Department of Health Business Administration Meiho UniversityPingtung County 912TaiwanChina Division of Colorectal Surgery Department of SurgeryCheng-Hsin General HospitalTaipei 112TaiwanChina

BACKGROUND Patients with colorectal cancer(CRC)undergo surgery,as well as perioperative chemoradiation or adjuvant chemotherapy primarily based on the tumor–node–metastasis(TNM)cancer staging ***,treatment responses and prognostic outcomes of patients within the same stage vary *** potential use of novel biomarkers can improve prognostication and shared decision making before implementation into certain *** To investigate whether SUMF2,ADAMTS5,and PXDN methylation status could be associated with CRC *** We conducted a Taiwan region cohort study involving 208 patients with CRC recruited from TriService General Hospital and applied the candidate gene approach to identify three genes involved in oncogenesis pathways.A methylation-specific polymerase chain reaction(MS-PCR)and Epi TYPER DNA methylation analysis were employed to detect methylation status and to quantify the methylation level of candidate genes in tumor tissue and adjacent normal tissue from *** evaluated SUMF2,ADAMTS5,and PXDN methylation as predictors of prognosis,including recurrence-free survival(RFS),progression-free survival(PFS),and overall survival(OS),using a Cox regression model and Kaplan–Meier *** We revealed various outcomes related to methylation and *** shorter PFS and OS were associated with the CpG_3+CpG_7 hypermethylation of SUMF2 from tumor tissue compared with CpG_3+CpG_7 hypomethylation[hazard ratio(HR)=2.24,95%confidence interval(CI)=1.03-4.85 for PFS,HR=2.56 and 95%CI=1.08-6.04 for OS].By contrast,a significantly longer RFS was associated with CpG_2 and CpG_13 hypermethylation of ADAMTS5 from normal tissue compared with CpG_2 and CpG_13 hypomethylation[HR(95%CI)=0.15(0.03-0.71)for CpG_2 and 0.20(0.04-0.97)for CpG_13].The relationship between the methylation status of PXDN and the prognosis of CRC did not reach statistical *** Our study found that CpG_3+CpG_7 hypermethylation o

关键词： DNA methylation Biomarkers Tumor tissue Adjacent normal tissue Prognosis prediction Colorectal cancer

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POLARIZATION-SENSITIVE OPTICAL COHERENCE TOMOGRAPHY USING A MODIFIED BALANCE DETECTOR

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Journal of Innovative Optical Health Sciences 2012年第4期5卷 18-23页

作者： LI-PING YU JIAN-CHEN GUO LI-DEK CHOU TE-LUN MA jheng-SYONG WU JIANN-DER LEE CHIEN CHOU Center for Biomedical Engineering Chang Gung University Taoyuan 333 Taiwan Department of Biomedical Imaging and Radiological Science National Yang Ming University Taipei 112 Taiwan Graduate Institute of Electro-Optical Engineering Chang Gung University Taoyuan 333 Taiwan Department of Optics and Photonics National Central University Jhongli 320 Taiwan Department of Electrical Engineering Chang Gung University Taoyuan 333 Taiwan Graduate Institute of Electro-Optical Engineering and Center for Biomedical Engineering Chang Gung University Taoyuan 333 Taiwan

In conventional polarization sensitive optical coherence tomography(PS-OCT),phase retar-dation is obtained by the amplitude of P and S polarization only,and the fast axis angle is obtained by the phase difference in P and S polarizations via Hilbert *** this paper,we proposed a modifed PS OCT setup in which the phase retardation and fast axis angle are simply expressed as the function of the amplitude ofP and S polarization and their differential *** to the common-path feature between the two channels ofP and S polarization,the fuctuation in the measurement of phase retardation and fast axis angle caused by excess noise and phase noise from the laser source can be reduced by the differential signal of P and S polarization via a modified balance ***,the signal of phase retardation and fast angle axis in the deep layer of a porcine sample can be improved.

关键词： PS OCT modifed balanced detector Hilbert transformation

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4D printing of polyurethane paint-based composites

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International Journal of Smart and Nano Materials 2019年第3期10卷 237-248页

作者： jheng-Wun Su Wenxin Gao Khoinguyen Trinh Stuart M.Kenderes Ezgi Tekin Pulatsu Cheng Zhang Alan Whittington Mengshi Lin Jian Lin Department of Mechanical&Aerospace Engineering University of MissouriColumbiaMOUSA Department of Mechanical Engineering University of ArkansasFayettevilleARUSA Department of Geological Sciences Engineering University of MissouriColumbiaMOUSA Department of Food Systems&Bioengineering University of MissouriColumbiaMOUSA

In recent studies,polyurethane has shown multiple properties that make it an excellent candidate material in 4D *** this study,we present a simple and inexpensive additive method to print waterborne polyurethane paint-based composites by adding carboxymethyl cellulose(CMC)and silicon oxide(SiO2)nanoparticles to the *** first function of CMC and SiO_(2) is to improve rheological properties of the polyurethane paint for making a printable precursor,which improves the printing resolution and enhances additive ***,the composite precursors improve the curing rate of the polyurethane paint without changing its inherited shape memory ***,the printed composite parts shown enhanced mechanical strength compared with that of the parts printed with pure ***,the 3D printedpolyurethane-CMCandSiO_(2) parts exhibit time-resolved shape transformation upon heat *** the best of our knowledge,this is the first study of using the polyurethane paint as the precursor for 4D printing,which would open new possibilities in future applications in biomedical engineering,soft robotics and so on.

关键词： 4D printing polyurethane paint carboxymethyl cellulose silicon oxide

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Effect of Guar Gum,Konjac Gum and Carboxyl Methyl Cellulose on the Properties of Toast

Effect of Guar Gum,Konjac Gum and Carboxyl Methyl Cellulose ...

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第十四届国际谷物科技与面包大会暨国际油料与油脂发展论坛

作者： Jhih-ying Ciou Hsin-Hung Lin Albert Linton Charles Jenq-Sheng Chang Pei-Pei Lin Yung-Ho Chang jheng-Hua Lin Department of Hospitality Management MingDao University PeetowChanghua 52345Chinese Taipei

Various forms of bread are expended and many people consider it to be one of the oldest treated *** is a range of bread varieties due to the cleverness of bakers and their ability to control wheat gluten formed in *** is a rubbery mass with characteristics that allow it to deform,stretch,recover shape and trap *** extensive knowledge on the components of wheat flour,it still is great challenges at the art of bread *** should be more considered that the quantity of water used impacts dough consistency,starch gelatinization and the behavior of the protein (gluten),thereby affecting crumb *** mixing procedure also affects the quality of the bread, with even small variations affecting bread quality,while fermentation and proofing influence the specific volume of the bread(Sluimer,2005).According to previously studies,the baking industry has focused on loaf volume,crumb grain quality and bread texture as indicators of bread *** volume is dependent on the quantity and quality of the gluten in the flour,the increase in gas volume during baking as well as processing conditions(Hayman,Hoseney,& Faubion,1998;Shittu,Raji,& Sanni, 2007;Sluimer,2005).When Abdul-Hamid and Luan(2000) evaluated the functional properties of dietary fiber from defatted rice bran,they found that substitutions of wheat flour at 5%and 10% significantly reduced bread loaf volume and increased *** and others(2007) indicate that gums consist of a number of water-soluble polysaccharides come with different chemical structures and provide diverse functional properties such as gelling,thickening,stabilising,foaming,emulsifying, as well as inhibiting syneresis during a freeze thaw cycle,water-retention and textural enhancing properties,by controlling the water molecules *** previously reported showed guar gum is a coldwater soluble polysaccharide derived from the endosperm of guar beans by extraction and its polysaccharide consists of g

关键词： guar gum konjac gum carboxyl methyl cellulose toast

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Development an Intelligent Power Detection System for Mobile Robots

Development an Intelligent Power Detection System for Mobile...

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第二十七届中国控制会议

作者： Lin Yungchin Shiau Sheng V Jhuang jheng S Department of Electrical Engineering National Yunlin University of Science & TechnologyYunlin Department of Mechanical Engineering Wu-Feng Institute of Techonlogy

The paper presents an intelligent power detection system for a mobile *** use four current sensors to measure the current variety of the mobile robot,and use multilevel multisensor fusion method to detect current sensor and voltage signals ***,a two level method is used to isolate faulty measured value such that more exact current and voltage status to be *** this method,a redundant management method and a statistical prediction method are used in levels one and two,*** design the power detection and isolation module using HOLTEK microchip according to the redundant management *** module can transmit measured value and estimated statue to main controller（IPC） using series in-terface（RS232） .However,it is possible that this method is *** this case,the IPC can decide an exact power measured value and faulty status according the statistical signal prediction *** we can predict the residual power of mobile robots using polynomial regression ***,we implement the proposed method on the experiment scenario of can set a power threshold value to calculate the critical time for the mobile ***,experimental results are given to show the feasibility of the proposed method.

关键词： Intelligent power detection system Mobile robot Redundant management method Statistical signal prediction method Polynomial regression algorithm

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