Glucose detection in a highly scattering medium with diffuse photon-pair density wave

作     者：Li-Ping Yu Jheng-Syong Wu Sheng-Yi Chang Chien Chou 

作者机构：Biomedical Engineering Research CenterChang Gung University Taoyuan 333Taiwan Graduate Institute of Electro-Optical EngineeringChang Gung University Taoyuan 333Taiwan Institute of ChemistryA cademic SinicaNankangTaipei 115Taiwan Ph.D Program of Biomedical EngineeringChang Gung University Taoyuan 333Taiwan Department of MechanicsMing Chi University of Technology New Taipei 243Taiwan 

出 版 物：《Journal of Innovative Optical Health Sciences》 (创新光学健康科学杂志（英文）)

年 卷 期：2017年第10卷第1期

页      面：53-58页

核心收录：

学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 100401[医学-流行病与卫生统计学] 10[医学] 

基　　金：Ministry of Science and Technology (MOST) of Taiwan 

主　　题：Difuse photon-pair density wave glucose multiple scattering polarization gating spatial coherence gating. 

摘      要：We propose a novel optical method for glucose measurement based on difuse photon-pair density wave(DPPDW)in a multiple scattering medium(MSM)where the light scattering of photon-pair is induced by refractive index mismatch between scatters and phantom ***-mentally,the DPPDW propagates in MSM via a two frequency laser(TFL)beam wherein highly correlated pairs of linear polarized photons are *** reduced scattering coefficientμ2s and absorption coefficientμ2a of DPPDW are measured simultaneously in terms of the amplitude and phase measurements of the detected heterodyne signal under arrangement at different dis-tances between the source and detection fibers in *** results show that the sensitivity of glucose detection via glucose-induced change of reduced scattering coefficient(δμ′2)is 0.049%mM^(-1)in a 1%intralipid *** addition,the linear range ofδμ′2s vs glucose concentration implies that this DPPDW method can be used to monitor glucose concentration continuously and noninvasively subcutaneously.