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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2024年第1期25卷 83-90页

作者： Zhikun LIU yichao wu Abid Ali KHAN Lun LU Jianguo WANG Jun CHEN Ningyang JIA Shusen ZHENG Xiao XU Key Laboratory of Integrated Oncology and Intelligent Medicine of Zhejiang Province Department of Hepatobiliary and Pancreatic SurgeryAffiliated Hangzhou First People’s HospitalZhejiang University School of MedicineHangzhou310006China Zhejiang University School of Medicine Hangzhou310058China Department of Radiology Easter Hepatobiliary Surgery HospitalNaval Medical UniversityShanghai200438China Department of Hepatobiliary and Pancreatic Surgery the First Affiliated HospitalZhejiang University School of MedicineHangzhou310003China NHC Key Laboratory of Combined Multi-organ Transplantation Hangzhou310003China Department of Hepatobiliary and Pancreatic Surgery Shulan(Hangzhou)HospitalHangzhou310022China

Hepatocellular carcinoma(HCC)is one of the most common malignancies and is a major cause of cancer-related mortalities worldwide(Forner et al.,2018;He et al.,2023).Sarcopenia is a syndrome characterized by an accelerated loss of skeletal muscle(SM)mass that may be age-related or the result of malnutrition in cancer patients(Cruz-Jentoft and Sayer,2019).Preoperative sarcopenia in HCC patients treated with hepatectomy or liver transplantation is an independent risk factor for poor survival(Voron et al.,2015;van Vugt et al.,2016).

关键词： cancer patients

清热解毒方治疗宫颈癌放疗后急性放射性肠炎热毒伤络证的疗效及作用机制

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世界中医药 2024年第5期19卷 677-681页

作者：吴昊耿碧竹杨振宇吴易超丁井永谢燕东空军军医大学第二附属医院中医科西安710038 空军军医大学第二附属医院普外科西安710038 空军军医大学第二附属医院消化科西安710038

目的:探讨清热解毒方治疗宫颈癌放疗后急性放射性肠炎热毒伤络证的应用价值及对相关氧化因子的影响。方法:选取2021年3月至2022年3月空军军医大学第二附属医院收治的宫颈癌放疗后急性放射性肠炎患者74例作为研究对象,采用随机数字表法... 详细信息

目的:探讨清热解毒方治疗宫颈癌放疗后急性放射性肠炎热毒伤络证的应用价值及对相关氧化因子的影响。方法:选取2021年3月至2022年3月空军军医大学第二附属医院收治的宫颈癌放疗后急性放射性肠炎患者74例作为研究对象,采用随机数字表法随机分为观察组和对照组,每组37例。对照组给予复方谷氨酰胺肠溶胶囊口服治疗联合地塞米松灌肠,观察组在对照组基础上口服清热解毒方,连续治疗15 d,观察2组患者治疗前后症状改善有效率、放射性肠炎(ARE中文不是放射性肠炎给出中文)分级、维也纳肠镜分级、中医证候评分(里急后重、腹痛、腹泻、食欲不振等)、血清炎症介质超氧化物歧化酶(SOD)、丙二醛(MDA)水平。结果:观察组总有效率为91.67%(33/36),高于对照组的82.86%(29/35)(P<0.05)。2组患者治疗后放射性肠炎分级、维也纳肠镜分级、中医证候评分均有改善(P<0.05),MDA较治疗前降低(P<0.01),SOD较前升高(P<0.01)。用药15 d后,观察组ARE分级、维也纳肠镜分级、中医证候评分、MDA、SOD均优于对照组(P<0.05)。结论:清热解毒方口服联合复方谷氨酰胺肠溶胶囊治疗宫颈癌所致放射性肠炎急性期比单纯复方谷氨酰胺肠溶胶囊具有良好效果,其作用机制可能与抑制氧化因子相关。

关键词：放射性肠炎急性期热毒伤络证复方谷氨酰胺肠溶胶囊氧化机制清热解毒方临床疗效维也纳肠镜宫颈癌放疗

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Flow instability of supercritical hydrocarbon fuel in a multi-channel cooling system

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Chinese Journal of Aeronautics 2024年第2期37卷 283-295页

作者： yichao JIN Kun wu Xuejun FAN Institute of Applied Physics and Computational Mathematics Beijing 100094China Institute of Mechanics Chinese Academy of SciencesBeijing 100190China School of Engineering Science University of Chinese Academy of SciencesBeijing 100049China

Thermally-induced flow instabilities are a critical issue in multi-channel regenerative cooling *** particular,the interactions between Density-Wave Oscillations(DWO)and Flow Maldistribution(FMD)can result in complex and disastrous instability *** study investigates the instability behaviors of hydrocarbon fluid in a four-channel system with a constant heat flux ratio using both frequency-and time-domain *** the heat flux increases,the in-tube flow sequentially destabilizes in each channel and converges to new equilibrium states,leading to the emergence of FMD *** also causes the system eigenvalue to change repeatedly from negative to positive rather than increasing ***,the system eigenvalues are between those of the two most unstable channels,indicating that the stability behavior of the entire system is dictated by the most unstable *** FMD occurs,flow oscillations are activated in channels with weak stability,and the in-tube flow is observed to evolve into various flow patterns,including stable flow,self-sustained oscillation,oscillation divergence,quasiperiodic oscillation,and oscillation *** novel instability mode of oscillation excursion involves a spontaneous transition of operating *** oscillates from an equilibrium state and then stabilizes at a new operational state after oscillation-induced ***,the newfound stable state may also be only temporary,with the in-tube flow regressing to the initial state,resulting in quasi-periodic oscillation.

关键词： Cooling Supercritical fluids Hydrocarbons Flow instability Flow maldistribution Density-wave oscillations

基于酚醚结构的偕胺肟基聚合物的制备及U(Ⅵ)吸附行为研究

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中国科学：化学 2024年第7期54卷 1117-1126页

作者：唐震巽吴一超王子龙郝梓淇曲钊姬灌宇王祥科资源环境系统优化教育部重点实验室华北电力大学环境科学与工程学院北京102206

核能作为一种低碳清洁的能源,是国家重点发展对象之一.铀元素是核能的重要组成部分,但我国陆地铀矿储量有限,限制了核能的发展.海洋中共有约45亿吨铀,可满足核能的长期发展需要.本文从材料结构设计出发,利用廉价的工业化原料四氟对苯二... 详细信息

核能作为一种低碳清洁的能源,是国家重点发展对象之一.铀元素是核能的重要组成部分,但我国陆地铀矿储量有限,限制了核能的发展.海洋中共有约45亿吨铀,可满足核能的长期发展需要.本文从材料结构设计出发,利用廉价的工业化原料四氟对苯二腈(TFTPN)与依昔苯酮(Exi)/4,4′-二羟基苯偶酰(DDB)进行交联及偕胺肟功能化,制备出三种酚醚结构的U(Ⅵ)吸附材料:ExiF-AO、ExiF-2-AO和DDBF-AO,并对材料结构/配体与吸附性能间的关系进行探究.结果表明,相比结构相似的线性聚合物ExiF-AO和DDBF-AO,网状交联结构的ExiF-2-AO具有更强的吸附能力,吸附量达347.5 mg/g,同时具备较好的可回收性与理化稳定性.本文从分子结构层面探讨了材料结构对U(Ⅵ)吸附的影响,为用于大规模海水提铀的功能材料的设计、制备提供了借鉴.

关键词：共价有机聚合物偕胺肟铀吸附

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The highly selective catalytic hydrogenation of CO_(2)to CO over transition metal nitrides

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Chinese Journal of Chemical Engineering 2022年第3期35卷 248-254页

作者： yichao wu Zhiwei Xie Xiaofeng Gao Xian Zhou Yangzhi Xu Shurui Fan Siyu Yao Xiaonian Li Lili Lin Institute of Industrial Catalysis State Key Laboratory of Green Chemistry Synthesis TechnologyCollege of Chemical EngineeringZhejiang University of TechnologyHangzhou 310014China Key Laboratory of Biomass Chemical Engineering of Ministry of Education College of Chemical and Biological EngineeringZhejiang UniversityHangzhou 310027China

Three transition metal-like facet centered cubic structured transition metal nitrides,γ-Mo_(2)N,β-W_(2)N andδ-NbN,are synthesized and applied in the reaction of CO_(2)hydrogenation to *** the three nitride catalysts,theγ-Mo_(2)N exhibits superior activity to target product CO,which is 4.6 and 76 times higher than the other two counterparts ofβ-W_(2)N andδ-NbN at 600℃,***,γ-Mo_(2)N exhibits excellent stability on both cyclic heating-cooling and high space velocity steady state *** deactivation degree of cyclic heating-cooling evaluation after 5 cycles and long-term stability performance at 773 and 873 K in 50 h are all less than 10%.In-situ XRD and kinetic studies suggest that theγ-Mo_(2)N itself is able to activate both of the reactants CO_(2)and H_(2).Below 400℃,the reaction mainly occurs at the surface ofγ-Mo_(2)N ***_(2)and H_(2)competitively adsorbe on the surface of catalyst and CO_(2)is the relatively stronger surface *** a higher temperature,the interstitial vacancies of theγ-Mo_(2)N can be reversibly filled with the oxygen from CO_(2)*** of the surface and bulk phase sites ofγ-Mo_(2)N participate in the high temperature CO_(2)hydrogenation pathway.

关键词： Carbon dioxide Chemical reaction Catalysis Reverse water gas shift(RWGS)reaction Transition metal nitride In-situ X-ray diffraction characterization

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细菌根际黏附的界面作用机制研究

华中农业大学学报 2024年第4期43卷 25-32页

作者：陈彦昭许书麟渠晨晨张铭高春辉吴一超戴珂黄巧云蔡鹏华中农业大学资源与环境学院/农业微生物资源发掘与利用全国重点实验室武汉430070

界面作用是细菌在环境中黏附、定殖、形成生物膜和发挥生态功能的基础和前提,对植物吸收养分、病原微生物拮抗具有重要意义。微生物-植物根际相互作用研究大多数从生态学和分子生物学角度出发,应用多种组学手段研究根系分泌物对于根际... 详细信息

界面作用是细菌在环境中黏附、定殖、形成生物膜和发挥生态功能的基础和前提,对植物吸收养分、病原微生物拮抗具有重要意义。微生物-植物根际相互作用研究大多数从生态学和分子生物学角度出发,应用多种组学手段研究根系分泌物对于根际微生物定殖数量、群落组成和生理功能的影响,忽略了细菌定殖过程中物理、化学的界面作用机制及其对黏附的贡献。本文从界面作用机制出发,探讨了不同类型根系分泌物对细菌表面性质、细菌胞外聚合物(EPS)分子组成以及黏附功能的调控作用;梳理了黏附过程中细菌-植物生物大分子相互作用的主要模式及其微观机制;归纳了根际定殖过程可视化研究方法和微生物-植物生物大分子相互作用的分析手段;提出了根际生物分子组成分析、黏附蛋白质功能预测、根际定殖原位观测方法等亟需加强的研究方向。

关键词：界面作用根际定殖根系分泌物胞外多糖黏附蛋白质

Zooming in to acquire micro-reaction:Application of microfluidics on soil microbiome

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Soil Ecology Letters 2022年第3期4卷 213-223页

作者： Xiongkun Zhang Shan wu Xiaojie Sun Monika Mortimer yichao wu Ming Zhang Qiaoyun Huang Peng Cai State Key Laboratory of Agricultural Microbiology College of Resources and EnvironmentHuazhong Agricultural UniversityWuhan 430070China Institute of Environmental and Health Sciences College of Quality and Safety EngineeringChina Jiliang UniversityHangzhou 310018China

Microfluidics confers unique advantages in microbiological studies as these devices can accurately replicate the micro-and even nano-scale structures of soil to simulate the habitats of *** not only helps us understand the spatial distribution of bacterial communities(such as biofilms),but also provides mechanistic insights into microbial behaviors including chemotaxis and horizontal gene transfer(HGT).Microfluidics provides a feasible means for real-time,in situ studies and enables indepth exploration of the mechanisms of interactions in the soil *** review aims to introduce the basic principles of microfluidic technology and summarize the recent progress in microfluidic devices to study bacterial spatial distribution and functions,as well as biological processes,such bacterial chemotaxis,biofilm streamers(BS),quorum sensing(QS),and *** challenges in and future development of microfluidics for soil microbiological studies are also discussed.

关键词： Microfluidics Soil bacteria Biofilms Chemotaxis Quorum sensing Horizontal gene transfer

Ⅱ类射线装置审批权限下放及管理可行性研究——以广西为例

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辐射防护通讯 2024年第4期44卷 38-43页

作者：李丽红刘静西吴易超易鹞徐聘石伟力广西壮族自治区辐射环境监督管理站南宁530222

党的十八大明确提出:“深化行政审批制度改革,继续简政放权,推动政府职能向创造良好发展环境、提供优质公共服务、维护社会公平正义转变。”为进一步深化生态环境领域简政放权改革,推动辐射环境领域“放管服”改革,服务广西社会经济高... 详细信息

党的十八大明确提出:“深化行政审批制度改革,继续简政放权,推动政府职能向创造良好发展环境、提供优质公共服务、维护社会公平正义转变。”为进一步深化生态环境领域简政放权改革,推动辐射环境领域“放管服”改革,服务广西社会经济高质量发展,广西拟将Ⅱ类射线装置核技术利用项目的审批权限下放至各设区市。本文通过调查、分析广西各设区市审批、监管能力,确定该项目审批权限下放的可行性。

关键词：射线装置审批可行性对策研究

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Small particles,big effects:How nanoparticles can enhance plant growth in favorable and harsh conditions

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Journal of Integrative Plant Biology 2024年第7期66卷 1274-1294页

作者： Jie Wang Honghong wu yichao Wang wuwei Ye Xiangpei Kong Zujun Yin Zhengzhou Research Base State Key Laboratory of Cotton Bio‐breeding and Integrated UtilizationSchool of Agricultural SciencesZhengzhou UniversityZhengzhou 450001China State Key Laboratory of Cotton Bio‐breeding and Integrated Utilization Institute of Cotton ResearchChinese Academy of Agricultural SciencesAnyang 455000China National Key Laboratory of Crop Genetic Improvement Huazhong Agricultural UniversityWuhan 430070China School of Engineering Design and Built EnvironmentWestern Sydney UniversityPenrith NSW 2751Australia Western Agricultural Research Center Chinese Academy of Agricultural SciencesChangji 831100China The Key Laboratory of Plant Development and Environmental Adaptation Biology Ministry of EducationCollege of Life SciencesShandong UniversityQingdao 266237China

By 2050,the global population is projected to reach 9 billion,underscoring the imperative for innovative solutions to increase grain yield and enhance food *** has emerged as a powerful tool,providing unique solutions to this ***(NPs)can improve plant growth and nutrition under normal conditions through their high surface-to-volume ratio and unique physical and chemical ***,they can be used to monitor crop health status and augment plant resilience against abiotic stresses(such as salinity,drought,heavy metals,and extreme temperatures)that endanger global *** of NPs can enhance stress tolerance mechanisms in plants,minimizing potential yield losses and underscoring the potential of NPs to raise crop yield and *** review highlights the need for a comprehensive exploration of the environmental implications and safety of nanomaterials and provides valuable guidelines for researchers,policymakers,and agricultural *** thoughtful stewardship,nanotechnology holds immense promise in shaping environmentally sustainable agriculture amid escalating environmental challenges.

关键词： abiotic stress agricultural defense system nano-particles nanotechnology oxidative stress reactive oxygen species toxicity

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砂卵石地层大直径盾构施工的关键技术

城市轨道交通研究 2024年第1期27卷 196-199页

作者：王春波孙建营武亦超方华昌中国人民武装警察部队警官学院基础部成都610213 中交一公局集团有限公司北京100024

[目的]总结分析砂卵石地层大直径盾构施工中盾构机选型、盾构始发与接收、盾构掘进姿态控制等施工关键技术,并提出具体的施工控制参数与施工控制措施,以减轻刀盘刀具磨损、降低地层损失、减小地层沉降变形。[方法]针对砂卵石地层结构松... 详细信息

[目的]总结分析砂卵石地层大直径盾构施工中盾构机选型、盾构始发与接收、盾构掘进姿态控制等施工关键技术,并提出具体的施工控制参数与施工控制措施,以减轻刀盘刀具磨损、降低地层损失、减小地层沉降变形。[方法]针对砂卵石地层结构松散、颗粒无胶结或弱胶结、颗粒粒径大、透水性强的工程结构特性,采用理论分析、现场监测等方法,从盾构机选型、盾构始发接收、盾构掘进姿态控制、盾构刀盘刀具的检测维修等方面深入分析砂卵石地层大直径盾构施工关键技术。[结果及结论]大直径盾构的刀盘开口率、刀盘刀具类型、渣土改良方案等应根据地层结构特性进行特殊设计,且有利于盾构排渣和超前切割;盾构井端头宜采取地层注浆加固、大管棚支护、施工降水等综合加固措施以保证大盾构始发或接收时地层的稳定;大直径盾构的掘进施工应重点控制刀盘转速、出渣量、出渣温度等参数,并应适当增大注浆量,提高渣土改良效果,避免过大超挖,保证地层损失处于合理范围内。采用上述施工参数与施工措施后,盾构掘进风险可控,施工质量与施工效率明显提升,同时大大降低了施工成本。

关键词：大直径盾构砂卵石地层刀盘刀具地层加固掘进姿态

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