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Shrinkage of ipsilateral taste buds and hyperplasia of contralateral taste buds following chorda tympani nerve transection

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Neural Regeneration Research 2015年第6期10卷 989-995页

作者： yi-ke li Juan-mei Yang yi-bo Huang Dong-dong Ren Fang-lu Chi Department of Otology and Skull Base Surgery Eye Ear Nose & Throat HospitalFudan University Shanghai Auditory Medical Center key Laboratory of Hearing Science Ministry of Health Department of Hearing and Speech Sciences Vanderbilt University

The morphological changes that occur in the taste buds after denervation are not well under- stood in rats, especially in the contralateral tongue epithelium. In this study, we investigated the time course of morphological changes in the taste buds following unilateral nerve transection. The role of the trigeminal component of the lingual nerve in maintaining the structural integrity of the taste buds was also examined. Twenty-four Sprague-Dawley rats were randomly divided into three groups： control, unilateral chorda tympani nerve transection and unilateral chorda tympani nerve transection ＋ lingual nerve transection. Rats were allowed up to 42 days of re- covery before being euthanized. The taste buds were visualized using a cytokeratin 8 antibody. Taste bud counts, volumes and taste receptor cell numbers were quantified and compared among groups. No significant difference was detected between the chorda tympani nerve transection and chorda tympani nerve transection ＋ lingual nerve transection groups. Taste bud counts, volumes and taste receptor cell numbers on the ipsilateral side all decreased significantly compared with control. On the contralateral side, the number of taste buds remained unchanged over time, but they were larger, and taste receptor cells were more numerous postoperatively. There was no evidence for a role of the trigeminal branch of the lingual nerve in maintaining the structural integrity of the anterior taste buds.

关键词： nerve regeneration gustation cytokeratin tongue epithelium immunohistochemistry taste bud trigeminal nerve disorder NSFC grants neural regeneration

The observed difference of macrophage phenotype on different surface roughness of mineralized collagen

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Regenerative Biomaterials 2020年第2期7卷 203-211页

作者： Jun li Yu-Jue Zhang Zhao-Yong Lv Kun liu Chun-Xiu Meng Bo Zou ke-yi li Feng-Zhen liu Bin Zhang Department of Oral and Maxillofacial Surgery School and Hospital of StomatologyShandong University&Shandong Provincial Key Laboratory of Oral Tissue Regeneration&Shandong Engineering Laboratory for Dental Materials and Oral Tissue RegenerationJinanShandong 250012People’s Republic of China liaocheng People’s Hospital Medical College of Liaocheng UniversityLiaocheng 252000People’s Republic of China Department of Materials Science and Engineering Tsinghua UniversityBeijing 100084People’s Republic of China

Biomaterials regulate macrophages and promote regeneration function,which is a new hot pot in tissue engineering and regenerative *** research based on macrophage materials biology has appeared happy future,but related research on regulating macrophages and promoting tissue regeneration is still in its *** surface roughness of biomaterials is one of the important factors affecting macrophage *** study also found that the surface roughness of many biomaterials regulating macrophage polarization,but not including mineralized collagen(MC).In this study,we designed and fabricated MC with different roughness and investigated the influence of MC with different roughness on *** the study,we found that on the rough surface of MC,macrophages exhibited M1 phenotype-amoeboid morphology and high-level secretory of inflammatory factor(tumor necrosis factor-a and interleukin-6),while smoother surface exhibited M2 *** data will be beneficial to understand the mechanism deeply and enrich biomaterials tissue regeneration theory,provide a new train of thought biomaterials inducing tissue regeneration and repair and guide the optimum design of new biomaterials,development and reasonable applications.

关键词： inflammatory response mineralized collagen roughness macrophage polarization

Enhancement of BMP-2 and VEGF carried by mineralized collagen for mandibular bone regeneration

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Regenerative Biomaterials 2020年第4期7卷 435-440页

作者： Kun liu Chun-Xiu Meng Zhao-Yong Lv Yu-Jue Zhang Jun li ke-yi li Feng-Zhen liu Bin Zhang Fu-Zhai Cui Shandong Provincial key Laboratory of Oral Tissue Regeneration Shandong Engineering Laboratory for Dental Materials and Oral Tissue RegenerationSchool and Hospital of StomatologyShandong UniversityJinanShandong 250012P.R.China liaocheng People’s Hospital Medical College of Liaocheng UniversityLiaocheng 252000P.R.China College of Materials Science and Engineering of liaocheng University Liaocheng 252000P.R.China Department of Materials Science and Engineering Tsinghua UniversityBeijing 100084P.R.China

Repairing damage in the craniofacial skeleton is *** bones require intramembranous ossification to generate tissue-engineered bone grafts via angiogenesis and ***,we designed a mineralized collagen delivery system for BMP-2 and vascular endothelial growth factor(VEGF)for implantation into animal models of mandibular ***-2/VEGF were mixed with mineralized collagen which was implanted into the rabbit *** were divided into(i)controls with no growth factors;(ii)BMP-2 alone;or(iii)BMP-2 and VEGF *** and hisomputed tomography and histological staining were performed to assess bone *** bone formation was higher in BMP-2 and BMP-2-VEGF groups in which angiogenesis and osteogenesis were *** highlights the use of mineralized collagen with BMP-2/VEGF as an effective alternative for bone regeneration.

关键词： bone regeneration mineralized collagen BMP-2 VEGF

Space-time cooperative diversity scheme using full feedback

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The Journal of China Universities of Posts and Telecommunications 2009年第3期16卷 8-13页

作者： SUN De-chun,yi ke-chu,li Xiao-hui State key Laboratory of Integrated Service Networks,Xidian University,Xi’an 710071,china State key Laboratory of Integrated Service Networks Xidian University Xi'an 710071 china

This article proposes a new space-time cooperative diversity scheme called full feedback-based cooperative diversity scheme （FFBCD）. In contrast to the conventional adaptive space-time cooperative diversity schemes that utilize the feedback from only the destination node, the new scheme utilizes the feedback from both the destination node and the cooperation node. With the feedback from the destination node, the occasional successful reception of the destination node in the information distribution stage can be detected, thus avoiding unnecessary retransmissions in the information delivery stage. The feedback from the cooperation node indicates the receiving state of the cooperation node in the information distribution stage, and the source node and the cooperation node will not perform cooperative retransmission during the information delivery stage unless the cooperation node is received successfully in the information distribution stage. In this way the new scheme can reduce the number of transmission attempt and improve the channel utilization. The expressions of the average number of transmission attempt are given. Numerical approximations and simulation results both show that the new scheme performs better than the non-cooperative scheme and the conventional adaptive space-time cooperative diversity scheme.

关键词： space-time cooperative diversity simple feedback adaptive cooperative diversity transmission attempt

Geology and mineralization of the Bayan Obo supergiant carbonatite-type REE-Nb-Fe deposit in Inner Mongolia, China: A review

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China Geology 2023年第4期6卷 716-750,I0004,I0005页

作者： yi-ke li Chang-hui ke Hong-quan She Deng-hong Wang Cheng Xu An-jian Wang Rui-ping li Zi-dong Peng Ze-ying Zhu Kui-feng Yang Wei Chen Jian-wei Zi Wen-lei Song Yong-gang Zhao li Zhang Hong Yu Bin Guo Sheng-quan Zhou Xing-yu Yuan Jing-yao liu MNR key Laboratory of Metallogeny and Mineral Assessment Institute of Mineral ResourcesChinese Academy of Geological SciencesBeijing 100037China key Laboratory of Orogenic Belts and Crustal Evolution School of Earth and Space SciencesPeking UniversityBeijing 100871China key Laboratory of Mineral Resources Institute of Geology and GeophysicsChinese Academy of SciencesBeijing 100029China State key Laboratory of Geological Processes and Mineral Resources China University of GeosciencesWuhan 430074China John de Laeter Centre Curtin UniversityBentleyWA 6102Australia State key Laboratory of Continental Dynamics Department of GeologyNorthwest UniversityXi’an 710069China Bayan Obo Iron Mine Baotou Steel(Group)Co.Ltd.Inner MongoliaBaotou 014080China

The Bayan Obo supergiant carbonatite-related rare-earth-element-niobium-iron(REE-Nb-Fe) endogenetic deposit(thereafter as the Bayan Obo deposit), located at 150 km north of Baotou City in the Inner Mongolia Autonomous Region, is the largest rare-earth element(REE) resource in the world. Tectonically,this deposit is situated on the northern margin of the North China Craton and adjacent to the Xing’anMongolian orogenic belt to the south. The main strata within the mining area include the Neoarchean Se’ertengshan Group and the Mesoproterozoic Bayan Obo Group. Generally, the rare earth, niobium, and iron mineralization within the deposit are intrinsically related to the dolomite carbonatites and the extensive alteration of the country rocks caused by the carbonatite magma intrusion. The alteration of country rocks can be categorized into three types: contact metasomatism(anti-skarn and skarn alteration), fenitization,and hornfelsic alternation. As indicated by previous studies and summarized in this review, the multielement mineralization at Bayan Obo is closely associated with the metasomatic replacement of siliceous country rocks by carbonatite magmatic-hydrothermal fluids. The metasomatic process is comparable to the conventional skarnification that formed due to the intrusion of intermediate-acid magmatic rocks into limestone strata. However, the migration pattern of Si O2, Ca O, and Mg O in this novel metasomatic process is opposite to the skarn alteration. Accordingly, this review delineates, for the first time, an antiskarn metallogenic model for the Bayan Obo deposit, revealing the enigmatic relationship between the carbonatite magmatic-hydrothermal processes and the related iron and rare earth ***, this study also contributes to a better understanding of the REE-Nd-Fe metallogenetic processes and the related fluorite mineralization at the Bayan Obo deposit.

关键词： Rare earth elements Niobium ore Iron ore Fluorite ore Igneous carbonatite Fenitization Metasomatism Anti-skarn Bayan Obo

Magneto‑Dielectric Synergy and Multiscale Hierarchical Structure Design Enable Flexible Multipurpose Microwave Absorption and Infrared Stealth Compatibility

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Nano-Micro Letters 2025年第2期17卷 401-416页

作者： Chen li Leilei liang Baoshan Zhang yi Yang Guangbin Ji School of Electronic Science and Engineering Nanjing UniversityNanjing 210093People’s Republic of China College of Materials Science and Technology Nanjing University of Aeronautics and AstronauticsNanjing 210016People’s Republic of China

Developing advanced stealth devices to cope with radar-infrared(IR)fusion detection and diverse application scenarios is increasingly demanded,which faces significant challenges due to conflicting microwave and IR cloaking mechanisms and functional integration ***,we propose a multiscale hierarchical structure design,integrating wrinkled MXene IR shielding layer and flexible Fe_(3)O_(4)@C/PDMS microwave absorption *** top wrinkled MXene layer induces the intensive diffuse reflection effect,shielding IR radiation signals while allowing microwave to pass ***,the permeable microwaves are assimilated into the bottom Fe_(3)O_(4)@C/PDMS layer via strong magneto-electric *** theoretical and experimental optimization,the assembled stealth devices realize a near-perfect stealth capability in both X-band(8–12 GHz)and long-wave infrared(8–14μm)wavelength ***,it delivers a radar cross-section reduction of−20 dB m^(2),a large apparent temperature modulation range(ΔT=70℃),and a low average IR emissivity of ***,the optimal device demonstrates exceptional curved surface conformability,self-cleaning capability(contact angle≈129°),and abrasion resistance(recovery time≈5 s).This design strategy promotes the development of multispectral stealth technology and reinforces its applicability and durability in complex and hostile environments.

关键词： Microwave absorption Radar-infrared compatible stealth Wrinkled MXene Magneto-dielectric synergy Multifunction

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导电聚苯胺的研究及其应用前景

建材世界 2009年第5期30卷 8-11页

作者：柯一礼武汉理工大学材料科学与工程学院武汉430070

聚苯胺是种典型的导电高分子材料。由于具有结构多样化,电导率较高,掺杂机制独特,物理性能优异,环境稳定性好,且原料廉价易得,合成方法简便等一系列优点,而成为当今最具应用前景的导电高分子材料之一,由于结构的特殊性,使其可以在生活... 详细信息

聚苯胺是种典型的导电高分子材料。由于具有结构多样化,电导率较高,掺杂机制独特,物理性能优异,环境稳定性好,且原料廉价易得,合成方法简便等一系列优点,而成为当今最具应用前景的导电高分子材料之一,由于结构的特殊性,使其可以在生活的各个领域发挥功用。该文综述聚苯胺的结构,导电机理及主要合成手段,介绍了聚苯胺的功能及应用前景。

关键词：导电高分子聚苯胺掺杂

Application of the improved dung beetle optimizer,muti-head attention and hybrid deep learning algorithms to groundwater depth prediction in the Ningxia area,China

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Atmospheric and Oceanic Science Letters 2025年第1期18卷 18-23页

作者： Jiarui Cai Bo Sun Huijun Wang yi Zheng Siyu Zhou Huixin li Yanyan Huang Peishu Zong Collaborative Innovation Center on forecast and Evaluation of Meteorological Disasters/key Laboratory of Meteorological Disaster Ministry of Education/Joint International Research Laboratory of Climate and Environment ChangeNanjing University of Information Science and TechnologyNanjingChina Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai) ZhuhaiChina China Meteorological Administration Key Laboratory of Transportation MeteorologyNanjingChina Jiangsu Meteorological Observatory NanjingChina

Due to the lack of accurate data and complex parameterization,the prediction of groundwater depth is a chal-lenge for numerical *** learning can effectively solve this issue and has been proven useful in the prediction of groundwater depth in many *** this study,two new models are applied to the prediction of groundwater depth in the Ningxia area,*** two models combine the improved dung beetle optimizer(DBO)algorithm with two deep learning models:The Multi-head Attention-Convolution Neural Network-Long Short Term Memory networks(MH-CNN-LSTM)and the Multi-head Attention-Convolution Neural Network-Gated Recurrent Unit(MH-CNN-GRU).The models with DBO show better prediction performance,with larger R(correlation coefficient),RPD(residual prediction deviation),and lower RMSE(root-mean-square error).Com-pared with the models with the original DBO,the R and RPD of models with the improved DBO increase by over 1.5%,and the RMSE decreases by over 1.8%,indicating better prediction *** addition,compared with the multiple linear regression model,a traditional statistical model,deep learning models have better prediction performance.

关键词： Groundwater depth Multi-head attention Improved dung beetle optimizer CNN-LSTM CNN-GRU Ningxia

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无髯鸢尾新品种DUS测试性状筛选

植物遗传资源学报 2017年第5期18卷 905-912页

作者：李丛丛高亦珂阮丽丽范诸平刘蓉张启翔北京林业大学园林学院/花卉种质创新与分子育种北京市重点实验室/国家花卉工程技术研究中心/城乡生态环境北京实验室北京100083

植物新品种特异性、一致性和稳定性(DUS)测试是新品种保护的基础和依据,测试性状的筛选是DUS测试的核心。为制定无髯鸢尾DUS测试指南,初步确定测试性状43个,结合性状间R型聚类分析性状间相关性,去除相关性大、贡献较小的雌蕊长、叶长性... 详细信息

植物新品种特异性、一致性和稳定性(DUS)测试是新品种保护的基础和依据,测试性状的筛选是DUS测试的核心。为制定无髯鸢尾DUS测试指南,初步确定测试性状43个,结合性状间R型聚类分析性状间相关性,去除相关性大、贡献较小的雌蕊长、叶长性状,最终确定操作性强、区别明显的测试性状41个;利用品种间Q型聚类分析确定测试指南的分组性状4个;对性状进行分级及分布分析,保证无髯鸢尾测试指南的可行性,为无髯鸢尾品种测试与授权提供技术支持。

关键词：无髯鸢尾 DUS测试性状筛选