检索结果-南通市图书馆

Chemical Research in Chinese Universities 2003年第3期19卷 376-378页

作者： wu yi-tian LIU Ming-hua CAS Key Laboratory of Colloid and Interface Science Center for Molecular ScienceInstitute of ChemistryChinese Academy of SciencesBeijing 100080P.R.China

It has been found that via in situ coordination, non-amphiphilic dithizonecan be spread to form a colored Langmuir film. Various morphologies could be obtained depending onthe metal ions added in the subphase. These results give a clue to expand the molecular film to formmaterial and clarify the characteristics of the Lang-muir films formed by alkyl-chain-freecompounds.

关键词： Langmuir film Dithizone Coordination Metal Morphology

Fabrication and Performance of a Low Operating Pressure Nanofiltration Poly(vinyl chloride) Hollow Fiber Membrane

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Polymer Science 2014年第3期32卷 377-384页

作者： Jian-hua Wang Yue-li wu Yong-hua Zhang 朱宝库 You-yi Xu MOE Key Laboratory of Macromolecular Synthesis and Functionalization MOE Engineering Research Center of Membrane and Water Treatment TechnologyDepartment of Polymer Science and EngineeringZhejiang University

A low operating pressure nanofiltration membrane is prepared by interfacial polymerization between m-phenylenediamine （MPDA） and trimesoyl chloride （TMC） using PVC hollow fiber membrane as supporting. A series of PVC nanofiltration membranes with different molecular weight cutoff （MWCO） can be obtained by controlling preparation conditions. Chemical and morphological characterization of the membrane surface was carried out by FTIR-ATR and SEM. MWCO was characterized by filtration experiments. The preparation conditions were investigated in detail. At the optimized conditions （40 min air-dried time, aqueous phase containing 0.5% MPDA, 0.05% SDS and 0.6% acid absorbent, oil phase containing 0.3% TMC, and 1 min reaction time）, under 0.3 MPa, water flux of the gained nanofiltration membrane reaches 17.8 L/m2-h, and the rejection rates of methyl orange and MgSO4 are more than 90% and 60%, respectively.

关键词： PVC Interracial polymerization Nanofiltration membrane Hollow fiber membrane.

Numerical Study of Flow and Heat Transfer Characteristics of Shell-and-Tube Molten Salt Electric Heater with Circularly Perforated Baffles

在线全文

学校读者我要写书评

暂无评论

Journal of Thermal Science 2025年第1期 24-33页

作者： LIN Yongjie ZHANG Cancan wu Yuting ZHANG yi LU Yuanwei Key Laboratory of Heat Transfer and Energy Conversion National User-Side Energy Storage Innovation Research and Development CenterBeijing University of Technology

Numerical simulations of the flow and heat transfer characteristics of four shell-and-tube molten salt electric heaters with different perforation rates was ***-and-tube electric heaters have the same geometry and tube arrangement,and all of them use single segmental baffles,but there exist four different baffle openings（φ）,i.e.,0%,2.52%,4.06%,and 6.31%.The results indicated that the reasonable baffle opening could significantly reduce the shell-side pressure drop,effectively decreasing the shell-side flow dead zone *** can eliminate the local high-temperature phenomenon on the surface of electric heating tubes,but the heat transfer coefficient is slightly *** perforated schemes significantly reduce shell-side pressure drop compared to the baseline solution without open *** particular,the φ=6.31% scheme exhibits the optimal performance among all the schemes,with a maximum reduction of up to 50.50% in shell-side pressure drop relative to the unopened holes *** heat transfer coefficient is the highest for φ=0%,exhibiting a range of5.26% to 5.73%,5.14% to 5.99%,and 7.31% to 8.54% higher than φ=2.52%,4.06%,and 6.31%,respectively,within the calculated *** composite index h/（Δp）1/3was higher for all open-hole solutions than that for the unopened-hole *** best overall performance was for φ=6.31%,which improved the composite index by15.29% to 17.18% over the unopened-hole solution.

关键词：

Geometric Phase in Optical Fiber

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Chinese Physics Letters 1999年第5期16卷 316-317页

作者： ZHOU yi wu Zhen-hua GE Mo-lin Center for Advanced Study Tsinghua UniversityBeijing 100084

An additional geometric phase viewed as Berry's phase is found in helically coiled monomode optical fiber when linear birefiingences are induced by *** phase appears when the optical axis and normal vector do not coin... 详细信息

关键词： material. optical fiber

Pharmacological targeting cGAS/STING/NF-κB axis by tryptanthrin induces microglia polarization toward M2 phenotype and promotes functional recovery in a mouse model of spinal cord injury

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第11期20卷 3287-3301页

作者： Ziwei Fan Mengxian Jia Jian Zhou Zhoule Zhu Yumin wu Xiaowu Lin yiming Qian Jiashu Lian Xin hua Jianhong Dong Zheyu Fang Yuqing Liu Sibing Chen Xiumin Xue Juanqing Yue Minyu Zhu ying Wang Zhihui huang Honglin Teng Department of Orthopedics(Spine Surgery) the First Affiliated Hospital of Wenzhou Medical UniversityWenzhouZhejiang ProvinceChina School of Pharmacy Hangzhou Normal UniversityHangzhouZhejiang ProvinceChina Department of Neurology The First Affiliated Hospital of Wenzhou Medical UniversityWenzhouZhejiang ProvinceChina Department of Pathology Affiliated Hangzhou First People’s HospitalSchool of MedicineWestlake UniversityHangzhouZhejiang ProvinceChina Department of Clinical Research Center Affiliated Hangzhou First People’s HospitalSchool of MedicineWestlake UniversityHangzhouZhejiang ProvinceChina

The M1/M2 phenotypic shift of microglia after spinal cord injury plays an important role in the regulation of neuroinflammation during the secondary injury phase of spinal cord *** of shifting microglia polarization from M1(neurotoxic and proinflammatory type)to M2(neuroprotective and anti-inflammatory type)after spinal cord injury appears to be *** possesses an anti-inflammatory biological ***,its roles and the underlying molecular mechanisms in spinal cord injury remain *** this study,we found that tryptanthrin inhibited microglia-derived inflammation by promoting polarization to the M2 phenotype in *** promoted M2 polarization through inactivating the cGAS/STING/NF-κB ***,we found that targeting the cGAS/STING/NF-κB pathway with tryptanthrin shifted microglia from the M1 to M2 phenotype after spinal cord injury,inhibited neuronal loss,and promoted tissue repair and functional recovery in a mouse model of spinal cord ***,using a conditional co-culture system,we found that microglia treated with tryptanthrin suppressed endoplasmic reticulum stress-related neuronal *** together,these results suggest that by targeting the cGAS/STING/NF-κB axis,tryptanthrin attenuates microglia-derived neuroinflammation and promotes functional recovery after spinal cord injury through shifting microglia polarization to the M2 phenotype.

关键词： cGAS/STING functional recovery microglia neuroinflammation neuroprotection nuclear factor-κB polarization spinal cord injury tryptanthrin

数字赋能乡村教育现代化的实然困境与优化路径

在线全文

学校读者我要写书评

暂无评论

教学与管理 2025年第1期 6-11页

作者：王倩吴家华胡恒钊安徽大学马克思主义学院合肥230601 江西农业大学马克思主义学院南昌330045

以数字赋能为发展契机,推进乡村教育现代化是中国式教育现代化的必然要求,也是乡村全面振兴的重要依托。在教育领域,数字技术蕴含着驱动乡村教育现代化发展的重要价值,能够有效扩大优质教育资源的覆盖范围、变革乡村教育形态、推动乡土... 详细信息

以数字赋能为发展契机,推进乡村教育现代化是中国式教育现代化的必然要求,也是乡村全面振兴的重要依托。在教育领域,数字技术蕴含着驱动乡村教育现代化发展的重要价值,能够有效扩大优质教育资源的覆盖范围、变革乡村教育形态、推动乡土文化的交流传播。但在推动数字赋能乡村教育现代化的实践中,面临着数字教育观念淡薄、数字基础条件不足、师生数字素养薄弱等现实阻碍,迫切需要从重塑价值观念、完善数字设施、培养师生数字素养、加强体制建设入手,为数字赋能乡村教育现代化发展注入新动力,以适应中国式教育现代化发展的新生态。

关键词：数字赋能乡村教育中国式教育现代化乡土文化

在线全文

学校读者我要写书评

暂无评论

溴乙烯在外电场中的解离性质研究

原子与分子物理学报 2025年第4期42卷 20-26页

作者：周华森韩博元努尔比耶·艾则孜章吴熠朱奕虹刘玉柱南京信息工程大学江苏省大气海洋光电探测重点实验室南京210044 江苏省大气环境与装备技术协同创新中心南京210044

溴乙烯具有极高的毒性,它不仅会污染环境,还会损害人类的身心健康.因此,研究它的分子结构及其解离方式,不仅具有重要的科学意义,而且也具有极高的社会意义.本文采用密度泛函理论(DFT),以B3LYP/6-31G++(d,p)基组,深入探索溴乙烯分子在0 V... 详细信息

溴乙烯具有极高的毒性,它不仅会污染环境,还会损害人类的身心健康.因此,研究它的分子结构及其解离方式,不仅具有重要的科学意义,而且也具有极高的社会意义.本文采用密度泛函理论(DFT),以B3LYP/6-31G++(d,p)基组,深入探索溴乙烯分子在0 V·nm^(-1)~80 V·nm^(-1)外电场的影响下,其分子结构和解离特性.通过计算,随着外电场的增强:分子总能量和碳碳双键(C=C)的键长减小,碳溴键(C-Br)的键长和偶极矩增大.能隙E_(G)先增大后减小,分子结构稳定性降低.红外光谱主要产生了6个特征吸收峰,且普遍存在红移现象.分子解离特性表现为:当外部电场强度升高时,势垒会显著减弱,直至达到154.26 V·nm^(-1)时,势垒就会完全消除,溴乙烯分子的解离能相应减弱,这表明,当外部电场强度升高时,溴乙烯分子会发生逐步的分解.因此,这一结论可以为进一步探讨溴乙烯分子和其相关的化合物的解离研究提供依据.

关键词：溴乙烯红外光谱外电场解离势能面降解

Infinitely Many Solutions to a Class of p-Laplace Equations

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

Acta Mathematicae Applicatae Sinica 2019年第4期35卷 770-779页

作者： yi-hua DENG College of Mathematics and Statistics Hengyang Normal University

In this paper, we study a class of p-Laplace equations. Using variational methods, we prove that there are two solutions and one of these solutions is nonnegative. Using recurrence method, we prove that there are infi... 详细信息

关键词： p-Laplace equation variational methods infinitely many solutions nonnegative solution

Analysis of the anti-T2DM components in dichloromethane fraction of Schisandra sphenanthera and its mechanism

在线全文

学校读者我要写书评

暂无评论

Traditional Medicine Research 2025年第1期10卷 27-43页

作者： Shi-Bo Feng Hai-Hui Jiang Hui-Li Kang yi Jiang hua-Wei Zhang Xiao-Mei Song Yu-Ze Li Wen-Li huang Dong-Dong Zhang Chong Deng School of Pharmacy Shaanxi University of Chinese MedicineXianyang 712046China School of Pharmacy and Shaanxi Qinling Application Development and Engineering Center of Chinese Herbal Medicine Shaanxi University of Chinese MedicineXianyang 712046China Key Laboratory for Research and Development of“Qin Medicine”of Shaanxi Administration of Traditional Chinese Medicine Xianyang 712046China Shaanxi Key Laboratory of Research and Application of“Taibai Qi Yao” Xianyang 712046China

Background:The type 2 diabetes mellitus(T2DM)pharmacodynamic study of various parts of Schisandra sphenanthera was conducted in the previous stage,and it was found that dichloromethane extracted part(SDP)had a significant hypoglycemic ***,the components of SDP were analyzed,and the specific mechanism of its anti-T2DM was ***:We used a high-fat,high-sugar diet in combination with streptozotocin to induce a T2DM rat model,and the model rats were divided into two groups according to body weight and blood ***,oral glucose tolerance test,fasting blood glucose,low density lipoprotein cholesterol,superoxide dismutase,insulin,glycated hemoglobin,total cholesterol,nonesterified free fatty acids,alanine aminotransferase,high-density lipoprotein cholesterol,aspartate aminotransferase,malondialdehyde,and glutathione peroxidase were measured,organ indices were calculated,and pathological sections of pancreas and liver were *** 16S rRNA V3–V4 region of intestinal flora was sequenced to explore the effect of SDP on biochemical indicators and intestinal *** on the above indicators,the anti-T2DM mechanism of SDP in Schisandra sphenanthera was ***:After six weeks of administration,the biochemical indices of diabetic rats were diminished compared to the control *** SDP could significantly increase the gut microbialα-diversity index,resulting in significant changes in the flora of T2DM rats,with increased richness and diversity,reduced harmful flora,and significantly back-regulated the levels of acetic acid,propionic acid,and butyric ***:SDP can improve the symptoms associated with elevated blood glucose,dyslipidemia,elevated fasting insulin levels,and damaged glucose tolerance in *** against T2DM may be through the control of intestinal flora to normalize and exert anti-diabetic effect;its main active components may be lignans and terpenoids.

关键词： Schisandra sphenanthera T2DM intestinal flora HPLC

Effect of NF-κB p65 antisense oligodeoxynucleotide on transdifferentiation of normal human lens epithelial cells induced by transforming growth factor-β2

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2016年第1期9卷 29-32页

作者： Chao Liu Xao-Li wu Xin-yi wu Zhen-hua Zhang Xiao-hua Liu Department of Ophthalmology Qilu Hospital Shandong University Jinan 250012 Shandong Province China Department of Ophthalmology Central Hospital of QingdaoQingdao 266042 Shandong Province China Department of Ophthalmology Rongjun Hospital of Shandong Jinan 250013 Shandong Province China Department of Stomatology Central Hospital of QingdaoQingdao 266042 Shandong Province China

AIM：To study the inhibition of nuclear factor kappa-B p65（NF-κB p65）antisense oligodeoxynucleotide（ASODN）on transdifferentiation of normal human lens epithelial cells induced by transforming growth factor-β2（TGF-β2）.·M ETHODS：NF-κBp65ASODNand NF-κBp65missense oligodeoxynucleotide（MSODN）were designed and *** lens epithelial cell line（HLE B-3）cells were prepared for study and divided into 7 *** group was HLE B-3 cells cultured in dulbecco’s modified eagle medium（DMEM）.T1,T2,and T3 group were HLE B-3 cells cultured in DMEM with 10 ng/m L TGF-β2 for 6h,12h,24h respectively.A＋T group was HLE B-3 cells cultured with 10 ng/m L TGF-β2for 24h after transfected by NF-κB p65 ASODN for 24h.M＋T group was HLE B-3 cells cultured with 10 ng/m L TGF-β2 for 24h after transfected by NF-κB p65 MSODN for *** negative control group was HLE B-3 cells cultured with 10 ng/m L TGF-β2 for 24h after cultured with transfer agent（Hi Per Fect）for *** morphology was observed at different time points using an inverted *** expression of NF-κB p65 m RNA was detected with reverse transcription-polymerase chain reaction（RT-PCR）,and the expression ofα-smooth muscle actin（α-SMA）protein was assayed with ELISA.·RESULTS：With the TGF-β2 stimulation prolongation,the expression of NF-κB p65 m RNA and a-SMA protein increased in T1,T2,T3 groups compared with the control group,and the difference was statistically significant（〈0.05）.NF-κB p65 ASODN lowered the expression of NF-κB p65 m RNA andα-SMA protein induced by TGF-β***-κB p65 MSODN and Hi Per Fect did not lower the expression of NF-κB p65 m RNA andα-SMA protein induced by TGF-β*** difference between control group and A＋T group was not statistically significant（〉0.05）,but the difference among A＋T group and other groups was statistically significant（〈0.05）.·CONCLUSION：NF-κB p65 ASODN could lower the expression of NF-κB p65 m RNA andα-SMA protein induced by TGF-β2,and antagonized TGF-β2-induced transdifferentiati

关键词： nuclear factor kappa-B p65 antisenseoligodeoxynucleotide transforming growth factor-β2 α-smooth muscle actin lens epithelial cells