检索结果-南通市图书馆

Pregnancy Outcomes of In Vitro Fertilization with or without Ovarian Hyperstimulation Syndrome： A Retrospective Cohort Study in Chinese Patients

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2015年第23期128卷 3167-3172页

作者： Xuan Jiang Cheng-Yan Deng zheng-yi sun Wei-Lin Chen Han-Bi Wang Yuan-zheng Zhou Li Jin Department of Obstetrics and Gynecology Peking Union Medical College Hospital Chinese Academy of Medical Science and Peking Union Medical College Beijing 100730 China

Background： The effect of ovarian hyperstimulation syndrome （OH SS） on pregnancy outcomes of in vitro fertilization （IVF） patients is still ambiguous. Tbis study aimed to analyze pregnancy outcomes of IVF with or without OHSS in Chinese patients. Methods： A retrospective cohort study was undertaken to compare pregnancy outcomes between 190 women with OHSS and 197 women without OHSS. We examined the rates of clinical pregnancy, multiple pregnancies, miscarriage, live birth, preterm deliver）,, preterm birth before 34 weeks＇ gestation, cesarean delivery, low birth weight （LBW）, and small-for-gestational age （SGA） between the two groups. Odds ratios （ORs） and 95% confidence intervals （Cls） of measure of clinical pregnancy were also analyzed. Results： The clinical pregnancy rate of OHSS patients was significantly higher than that of non-OHSS patients （91.8% vs. 43.5%, P 〈 0.001）. After controlling for drug protocol and causes of infertility, the adjusted ORs of moderate OHSS and severe/critical OHSS for clinical pregnancy were 4.65 （95% CI, 1.86-11.61 ） and 5.83 （95% CI, 3.45-9.86）, respectively. There were no significant differences in rates of muhiple pregnancy （4.0% vs. 3.7%） and miscarriage （16.1% vs. 17.5%） between the two groups. With regard to ongoing clinical pregnancy, we also found no significant differences in the rates of live birth （82.1% vs. 78.8%）, preterm delivery （20.9% vs. 17.5%）, preterm birth before 34 weeks＇ gestation （8.6% vs. 7.9%）, cesarean delivery （84.9% vs. 66.3%）, LBW （30.2% vs. 23.5%）, and SGA （21.9% vs. 17.6%） between the two groups. Conclusion： OHSS, which occurs in the luteal phase or early pregnancy in IVF patients and represents abnormal transient hemodynamics, does not exert any obviously adverse effect on the subsequent pregnancy.

关键词： In Vitro Fertilization Miscarriage Ovarian Hyperstimulation Syndrome Pregnancy Outcome Pregnancy Rate

Application of the improved dung beetle optimizer,muti-head attention and hybrid deep learning algorithms to groundwater depth prediction in the Ningxia area,China

在线全文

学校读者我要写书评

暂无评论

Atmospheric and Oceanic Science Letters 2025年第1期18卷 18-23页

作者： Jiarui Cai Bo sun Huijun Wang yi zheng Siyu Zhou Huixin Li Yanyan Huang Peishu Zong Collaborative Innovation Center on forecast and Evaluation of Meteorological Disasters/Key Laboratory of Meteorological Disaster Ministry of Education/Joint International Research Laboratory of Climate and Environment ChangeNanjing University of Information Science and TechnologyNanjingChina Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai) ZhuhaiChina China Meteorological Administration Key Laboratory of Transportation MeteorologyNanjingChina Jiangsu Meteorological Observatory NanjingChina

Due to the lack of accurate data and complex parameterization,the prediction of groundwater depth is a chal-lenge for numerical *** learning can effectively solve this issue and has been proven useful in the prediction of groundwater depth in many *** this study,two new models are applied to the prediction of groundwater depth in the Ningxia area,*** two models combine the improved dung beetle optimizer(DBO)algorithm with two deep learning models:The Multi-head Attention-Convolution Neural Network-Long Short Term Memory networks(MH-CNN-LSTM)and the Multi-head Attention-Convolution Neural Network-Gated Recurrent Unit(MH-CNN-GRU).The models with DBO show better prediction performance,with larger R(correlation coefficient),RPD(residual prediction deviation),and lower RMSE(root-mean-square error).Com-pared with the models with the original DBO,the R and RPD of models with the improved DBO increase by over 1.5%,and the RMSE decreases by over 1.8%,indicating better prediction *** addition,compared with the multiple linear regression model,a traditional statistical model,deep learning models have better prediction performance.

关键词： Groundwater depth Multi-head attention Improved dung beetle optimizer CNN-LSTM CNN-GRU Ningxia

Factors Associated with Effectiveness of Treatment and Reproductive Outcomes in Patients with Thin Endometrium Undergoing Estrogen Treatment

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2015年第23期128卷 3173-3177页

作者： Si-Miao Liu Yuan-zheng Zhou Han-Bi Wang zheng-yi sun Jing-Ran Zhen Keng Shen Cheng-Yan Deng Jing-He Lang Department of Obstetrics and Gynecology Peking Union Medical College Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100730 China

Background： Thin endometrium is associated with poor reproductive outcomes; estrogen treatment can increase endomctrial thickness （EMT）. The aim of this retrospective cohort study was to investigate the factors influencing the effectiveness of estrogen treatment and reproductive outcomes after the treatment in patients with thin endometrium. Methods： Relevant clinical data of 101 patients with thin endometrium who had undergone estrogen treatment were collected. Possible factors influencing the effectiveness of treatment were analyzed retrospectively by logistic regression analysis. Eighty-seven infertile women without thin endometrium who had undergone assisted reproduction served as controls. The cases and controls were matched for age, assisted reproduction method, and number of embryos transferred. Reproductive outcomes of study and control groups were compared using Student＇s t-test and the Chi-square test. Results： At the end of estrogen treatment, EMT was ≥8 mm in 93/101 patients （92.1%）. Effectiveness of treatment was significantly associated with maximal pretreatment EMT （P = 0.017） and treatment duration （P = 0.004）. The outcomes of assisted reproduction were similar in patients whose treatment was successful in increasing EMT to ≥8 mm and the control group. The rate of clinical pregnancy in patients was associated with the number of good-quality embryos transferred in both fresh （P = 0.005） and frozen-thawed （P = 0.000） embryo transfer cycles. Conclusions： Thinner EMT before estrogen treatment requires longer treatment duration and predicts poorer treatment outcomes. The effectiveness of treatment depends on the duration of estrogen administration. Assisted reproductive outcomes of patients whose treatment is successful （i.e., achieves an EMT ≥8 mm） are similar to those of controls. The quality of embryos transferred is an important predictor of assisted reproductive outcomes in patients treated successfully with exogenous estrogen.

关键词： Assisted Reproduction Endometrial Thickness Estrogen Thin Endometrium

Factors Analysis of Spontaneous Abortion after Thawed-vitrified Blastocysts Transfer

在线全文

学校读者我要写书评

暂无评论

Journal of Reproduction and Contraception 2008年第1期19卷 35-42页

作者： Dong YANG zheng-yi sun Cheng-yan DENG Qi YU Fang-fang HE Department of Obstetrics and Gynecology Chinese Academy of Medical Science Peking Union Medical College Hospital Beijing 100730 China

Objective To investigate the factors resulting in spontaneous abortion after transferring frozen-thawing blastocysts.Methods A total of 108 cases transferring vitrified blastocysts were divided into two groups. abortion group （n=20） and ongoing group （n=88）. Cytogenetic analysis of apoblemas was performed in 12 cases of the abortion.Results The overall spontaneous abortion rate was 18.50%（20/108） and the early spontaneous rate was 16.67%（18/108）. A significant difference in maternal age was observed （abortion group： 33.3±4.0years, ongoing group： 31.0 ±3.6years, P=0.02）. No difference in other parameters was found. Cytogenetic analysis of apoblemas was obtained for 12 cases, and 2 specimens were contaminated. Seven often patients had abnormal *** The underlying cause of spontaneous abortion after transferring frozenthawing blastoeysts appears to be abnormal karyotypes. Advancing maternal age seems to increase the risk of spontaneous abortion.

关键词： thawed-vitrified blastocyst spontaneous abortion age chromosome

Exosomes:the next-generation therapeutic platform for ischemic stroke

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第5期20卷 1221-1235页

作者： Wenjing yin Hongyin Ma Yang Qu Jiaxin Ren yingying sun Zhen-Ni Guo yi Yang Stroke Center Department of NeurologyFirst Hospital of Jilin UniversityChangchunJilin ProvinceChina Neuroscience Research Center Department of NeurologyFirst Hospital of Jilin UniversityChangchunJilin ProvinceChina

Current therapeutic strategies for ischemic stroke fall short of the desired objective of neurological functional ***,there is an urgent need to develop new methods for the treatment of this *** are natural cell-derived vesicles that mediate signal transduction between cells under physiological and pathological *** have low immunogenicity,good stability,high delivery efficiency,and the ability to cross the blood–brain *** physiological properties of exosomes have the potential to lead to new breakthroughs in the treatment of ischemic *** rapid development of nanotechnology has advanced the application of engineered exosomes,which can effectively improve targeting ability,enhance therapeutic efficacy,and minimize the dosages *** in technology have also driven clinical translational research on *** this review,we describe the therapeutic effects of exosomes and their positive roles in current treatment strategies for ischemic stroke,including their antiinflammation,anti-apoptosis,autophagy-regulation,angiogenesis,neurogenesis,and glial scar formation reduction ***,it is worth noting that,despite their significant therapeutic potential,there remains a dearth of standardized characterization methods and efficient isolation techniques capable of producing highly purified *** optimization strategies should prioritize the exploration of suitable isolation techniques and the establishment of unified workflows to effectively harness exosomes for diagnostic or therapeutic applications in ischemic ***,our review aims to summarize our understanding of exosome-based treatment prospects in ischemic stroke and foster innovative ideas for the development of exosome-based therapies.

关键词： blood–brain barrier electroacupuncture engineering exercise exosomes ischemic stroke mesenchymal stem cells microglia neuroprotection stents

西风槽与副高相互作用的暴雨过程动热力场结构特征分析

在线全文

学校读者我要写书评

暂无评论

气象 2017年第2期43卷 151-165页

作者：侯淑梅郭俊建张磊郑怡孙兴池山东省气象台济南250031

利用常规气象观测、自动气象站加密观测、NCEP/NCAR(1°×1°,逐6 h)再分析以及FY 2C卫星云图等资料,分析了2007年8月15—18日发生在山东的一次暴雨过程中,西风槽与副热带高压(以下简称副高)相互作用三个阶段的热力、动力场结构特征。... 详细信息

利用常规气象观测、自动气象站加密观测、NCEP/NCAR(1°×1°,逐6 h)再分析以及FY 2C卫星云图等资料,分析了2007年8月15—18日发生在山东的一次暴雨过程中,西风槽与副热带高压(以下简称副高)相互作用三个阶段的热力、动力场结构特征。结果表明:整个过程先后经历了副高西进切变线缓慢西移、横槽南压副高减弱和横槽转竖副高南撤三个阶段,三个阶段的共同特征是中低层有切变线和θ_(se)锋区;700 hPa有低空急流;产生暴雨的对流云团具有后向传播特征,生命史中多次发生合并。三个阶段的不同点是:(1)副高西进过程中,锋区随高度向北倾斜,坡度小,切变线和θ_(se)锋区均为后倾,为典型的暖锋降水。暴雨区范围大,强度均匀,位于850 hPaθ_(se)锋区与暖脊的交界处的水汽辐合中心附近。饱和区宽广,伸展高度高。低层气旋性辐合、切变线辐合、锋面抬升是触发暴雨的动力机制,低空急流是暴雨增强机制。(2)副高减弱过程中,干冷空气分别从低层和中层侵入θ_(se)暖脊,θ_(se)锋区随高度先向北后向南,呈交错倾斜现象,坡度大,为典型的强对流降水,上升运动最为激烈。暴雨区范围小,强度大,分布不均,位于θ_(se)暖脊垂直方向轴线附近。饱和区狭窄,伸展高度高。锋面抬升运动是触发对流性强降水的主要动力机制,对流层中层干冷空气入侵是强降水的增强机制。(3)副高南撤过程中,θ_(se)锋区随高度向南倾斜,坡度大,呈前倾特征,为典型的高空槽降水。暴雨区狭长分散,强度弱,位于850 hPa切变线上、θ_(se)暖舌靠近锋区一侧。饱和区狭窄,伸展高度低。低层切变线辐合抬升是触发强降水动力机制,中层干侵入是降水增强机制。

关键词：副热带高压结构特征动力机制后向传播饱和区

用SPIDER法测量飞秒激光脉冲的光谱相位

在线全文

学校读者我要写书评

暂无评论

物理学报 2004年第9期53卷 3004-3009页

作者：王鹏王兆华魏志义郑加安孙敬华张杰中国科学院物理研究所光物理重点实验室北京100080

介绍了用SPIDER测量光谱相位的实验装置和模拟计算飞秒激光特性参数的原理 ;提出了Ω和τ等重要参数的确定方法 .实验上用自建的SPIDER进行了掺钛蓝宝石飞秒振荡器输出脉冲的相位测量 ,并以此为基础还原出了原输入脉冲的时域形式 ,模合... 详细信息

介绍了用SPIDER测量光谱相位的实验装置和模拟计算飞秒激光特性参数的原理 ;提出了Ω和τ等重要参数的确定方法 .实验上用自建的SPIDER进行了掺钛蓝宝石飞秒振荡器输出脉冲的相位测量 ,并以此为基础还原出了原输入脉冲的时域形式 ,模合计算所得的脉宽为 1 0 7fs。

关键词： SPIDER法飞秒激光光谱相干光谱相位脉冲宽度

在线全文

学校读者我要写书评

暂无评论

一种宽带低剖面动中通天线的设计

微波学报 2016年第5期32卷 28-31页

作者：胡俊毅郑文泉孙竹薛玲珑上海航天电子技术研究所上海201109

设计了一种宽带低剖面动中通天线。该天线采用长宽比为4∶1的阵列结构,阵列单元由加载金属栅格的二联装角锥喇叭天线、正交模耦合器和H-T波导功分器组合构成。在此基础上,通过合理利用空间分布,设计两套由E面及H面波导功分器混合组成的... 详细信息

设计了一种宽带低剖面动中通天线。该天线采用长宽比为4∶1的阵列结构,阵列单元由加载金属栅格的二联装角锥喇叭天线、正交模耦合器和H-T波导功分器组合构成。在此基础上,通过合理利用空间分布,设计两套由E面及H面波导功分器混合组成的低剖面馈电网络,并与阵列单元作级联。仿真结果表明:天线的工作带宽可达到30%,且具有较好的双极化收发共用特性,同时天线结构紧凑,剖面较低。

关键词：宽带低剖面波导喇叭天线正交模耦合器功分器

取卵日血清脑源性神经营养因子与辅助生育结局的相关性

在线全文

学校读者我要写书评

暂无评论

生殖与避孕 2012年第5期32卷 323-327,300页

作者：王雪甄璟然孙正怡郁琦刘美芝中国医学科学院、北京协和医学院、北京协和医院北京100730

目的:探讨取卵日血中脑源性神经营养因子(BDNF)能否预测卵母细胞质量和其后的卵胞质内单精子注射(ICSI)的妊娠结局。方法:总共纳入57例进行ICSI患者,在取卵日清晨抽取空腹静脉血,测量BDNF,E2和P的浓度。比较妊娠组与非妊娠组的相关数据... 详细信息

目的:探讨取卵日血中脑源性神经营养因子(BDNF)能否预测卵母细胞质量和其后的卵胞质内单精子注射(ICSI)的妊娠结局。方法:总共纳入57例进行ICSI患者,在取卵日清晨抽取空腹静脉血,测量BDNF,E2和P的浓度。比较妊娠组与非妊娠组的相关数据,并分析取卵日BDNF水平与E2、P、年龄和IVF相关数据之间的相关性。结果:妊娠组与非妊娠组的BNDF浓度无明显差异;取卵日BDNF浓度与E2和P呈明显正相关。BDNF与获卵数和成熟卵母细胞数成正相关。结论:尚不能用取卵日BDNF来预测ICSI的妊娠结局,但BDNF可能在卵母细胞发育成熟过程中发挥着重要作用。

关键词：脑源性神经营养因子(BDNF) 雌激素孕激素卵母细胞