检索结果-南通市图书馆

Chinese Journal of Structural Chemistry 2006年第9期25卷 1031-1034页

作者： CAI wen-Xuan wen yi-Hang su Hong FENG Yun-Long Institute of Physical Chemistry Zhejiang Key Laboratory for Reactive Chemistry on Solid Surfaces Zhejiang Normal University Jinhua 321004 China

The title complex Zn（HL）（NCS）2 （C14H18N4OS2Zn, Mr = 387.81, HL = N-（3-dimethyl-aminopropyl）-salicylaldimine） has been synthesized by the reaction of ZnSO4·7H2O with the Schiff base N-（3-dimethylaminopropyl）-salicylaldimine derived from the condensation reaction of 3-dimethylamino- 1-propylamine with salicyladehyde. It crystallizes in the monoclinic system, space group P21/n with a = 9.8360（8）, b = 14.930（1）, c = 12.277（1） A, β= 101.455（2）°, V= 1767.0（3） A 3, Z = 4, F（000） = 800, Dc= 1.458 g/cm^3 and ,μ（MoKα） = 1.631 mm^-1. The structure was refined to R = 0.0463 and wR = 0.1065 for 2681 observed reflections （1 〉 2σ（I））. Crystal analyses revealed that the Zn（Ⅱ） atom is coordinated by two nitrogen atoms of two NCS^-, and an oxygen atom as well as a nitrogen atom of amine from the neutral Schiff base ligand of N-（3-dimethyl-aminopropyl）-salicylaldimine to give a distorted tetrahedral geometry.

关键词： 3-dimethylamino-1-propylamine salieylaldehyde Sehiff base,

Red Emission of Eu（lll） Complex Based on 1-（7-（ferf-butyl）-g-ethyl-gH- carbazol-2-yl）-4,4,4-trifluorobutane-l,3-dione Excited by Blue Light

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Chemical Physics 2012年第6期25卷 697-702,I0004页

作者： Sheng-gui Liu wen-yi su Rong-kai Pan Xiao-ping Zhou School of Chemistry Science and Technology Zhanjiang Normal University Zhanjiang 524048 China

A new Eu（III） complex, EuL3（phen）, was synthesized, where L is the abbreviation of de- protonated 1-（7-（tert-butyl）-9-ethyl-gH-carbazol-2-yl）-4,4,4-trifluorobutane-l,3-dione （HL）, phen is the abbreviation of 1,10-phenanthroline. The Eu（III） complex was characterized by element analysis, IR, 1H NMR, UV-visible absorption spectroscopy, thermogravimetric anal- ysis （TGA）, and photoluminescence measurements （PL）. TGA shows that thermal stability of the complex is up to 325 ~C. PL measurement indicates that the Eu（III） complex exhibits intense red-emission and extends their excitation bands to visible region. LEDs device was successfully fabricated by precoating complex EuL3 （phen） onto 460 nm blue-emitting InGaN chip. The emission of device shows that the complex can act as red phosphor in combination with 460 nm blue-emitting chips. This europium complex based on 1-（7-（tert-butyl）-9- ethyl-9H-carbazol-2-yl）-4,4,4-trifluorobutane-l,3-dione is a kind of interesting red-emitting material excited by blue light, which could avoid the damage of excitation by UV light.

关键词： Carbazole fl-diketone Lanthanide complex Chemical synthesis Luminescence

Molecular docking-aided AIEgen design: concept, synthesis and applications

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China Chemistry 2024年第8期67卷 2614-2628页

作者： Jian-Qing Zhang Xiao-Yu Xu Fu-Sheng Liu Shu-Qiang Cao Yu-Xin Gui yi-wen su Xiao-Yu He Ji-Yuan Liang You-Quan Zou Department of Radiation and Medical Oncology Zhongnan Hospital of Wuhan UniversitySchool of Pharmaceutical SciencesWuhan UniversityWuhan 430071China Key Laboratory of Combinatorial Biosynthesis and Drug Discovery Ministry of EducationWuhan UniversityWuhan 430071China Tai Kang Center for Life and Medical Sciences Wuhan UniversityWuhan 430071China Department of Hepatobiliary Pancreatic SurgeryZhongnan Hospital of Wuhan UniversityWuhan 430071China

Aggregate-induced emission luminogens(AIEgens) have been widely used in biological imaging, chemical sensing, and disease treatments. The rational design and construction of AIEgens have received considerable research interests during the last few years. Herein, molecular docking-aided AIEgen design has been reasonably proposed and AIEgen TBQZY with excellent ~1O_(2) generation ability has been synthesized. The newly developed TBQZY could efficiently kill S. epidermidis and methicillinresistant S. epidermidis(MRSE) by tightly binding to bacteria and triggering the accumulation of ~1O_(2) in bacteria. TBQZY specifically regulated the immune system and polarized macrophages from M1 to M2 to accelerate the elimination of biofilm in vivo. In addition, healing acceleration was observed in chronic wounds treated with TBQZY, and side effects were ***, TBQZY had extraordinary potential for combating drug-resistant bacteria in the clinical setting. This research not only provided new concepts for the design of AIEgens, but also shed some lights on the discovery of drugs against drug-resistant bacteria.

关键词： AIEgen molecular docking drug-resistant bacteria biofilm chronic wounds healing

面向IDEA算法的多引擎高速并行化研究与设计

在线全文

学校读者我要写书评

暂无评论

计算机工程与设计 2017年第1期38卷 37-41页

作者：易肃汶戴紫彬李伟信息工程大学河南郑州450000

为解决IDEA算法在硬件实现过程中运算速度不高、工作模式单一的问题,设计支持ECB模式和CBC模式的IDEA密码处理引擎,基于多引擎并行处理关键因素提出IDEA多引擎并行处理架构。通过分析研究多引擎并行处理架构的任务调度机制,提出针对ECB... 详细信息

为解决IDEA算法在硬件实现过程中运算速度不高、工作模式单一的问题,设计支持ECB模式和CBC模式的IDEA密码处理引擎,基于多引擎并行处理关键因素提出IDEA多引擎并行处理架构。通过分析研究多引擎并行处理架构的任务调度机制,提出针对ECB模式和CBC模式的多引擎并行处理方式,采用轮询的方法进行任务的调度,充分发挥多引擎优势。采用Altera公司的Virtex6芯片进行FPGA仿真验证,仿真结果表明,在ECB模式和CBC模式下,吞吐率分别高达852.7 Mbps和798.3 Mbps。

关键词： IDEA算法 CBC模式 ECB模式多引擎调度机制

在线全文

学校读者我要写书评

暂无评论

应激生理指标皮质醇和α-淀粉酶的研究进展

军事医学 2017年第2期41卷 146-149页

作者：张懿苏文君蒋春雷第二军医大学心理与精神卫生学系精神病学教研室上海200433

随着社会竞争的日益激烈,工作和生活节奏加快,人们所承受的压力和挑战越来越多,暴露于日常生活应激的频率和强度也越来越大。持续、过强的应激暴露能破坏人体的生物学保护机制,并产生一系列生理、神经内分泌、神经生化、免疫功能及心理... 详细信息

随着社会竞争的日益激烈,工作和生活节奏加快,人们所承受的压力和挑战越来越多,暴露于日常生活应激的频率和强度也越来越大。持续、过强的应激暴露能破坏人体的生物学保护机制,并产生一系列生理、神经内分泌、神经生化、免疫功能及心理行为等方面的变化,最终引发一系列危害身心健康的疾病。鉴于应激已成为多种慢性疾病的重要病因或诱因,对应激生理指标特别是反映应激水平的客观检测指标的应用研究,将为应激相关疾病的防治提供依据。文献报道有多种应激生理指标,如皮质醇、α-淀粉酶、儿茶酚胺、热休克蛋白、促炎细胞因子等,该文针对应激反应最主要的两条通路:下丘脑-垂体-肾上腺(HPA)轴和交感通路,将代表性的皮质醇和α-淀粉酶作为应激生理指标作一综述。

关键词：应激生理指标皮质醇 α-淀粉酶应激性疾病

基于神经网络的污水BOD软测量补偿方法研究

在线全文

学校读者我要写书评

暂无评论

系统仿真学报 2009年第S2期21卷 83-85页

作者：王小艺刘载文苏震北京工商大学计算机与信息工程学院北京100048

针对污水处理过程中的水质参数BOD难以在线检测问题,在分析BOD软测量机理模型以及考虑废水生物处理过程的非线性和不确定性基础上,建立了基于BP神经网络的BOD软测量模型,对机理模型进行非线性误差补偿。经过仿真表明,该混合模型可较为... 详细信息

针对污水处理过程中的水质参数BOD难以在线检测问题,在分析BOD软测量机理模型以及考虑废水生物处理过程的非线性和不确定性基础上,建立了基于BP神经网络的BOD软测量模型,对机理模型进行非线性误差补偿。经过仿真表明,该混合模型可较为准确地对BOD参数进行估计,为构建BOD在线检测仪表提供理论参考。

关键词：污水处理 BOD 机理模型非线性补偿神经网络

Porous Organic Cage‑Based Quasi‑Solid‑State Electrolyte with Cavity‑Induced Anion‑Trapping Effect for Long‑Life Lithium Metal Batteries

在线全文

学校读者我要写书评

暂无评论

Nano-Micro Letters 2025年第2期17卷 376-386页

作者： Wei-Min Qin Zhongliang Li wen‑Xia su Jia‑Min Hu Hanqin Zou Zhixuan Wu Zhiqin Ruan Yue‑Peng Cai Kang Li Qifeng Zheng School of Chemistry South China Normal UniversityGuangzhou 510006People’s Republic of China Key Laboratory of Functional Metal‑Organic Compounds of Hunan Province College of Chemistry and Material ScienceHengyang Normal UniversityHengyang 421008People’s Republic of China Guangzhou Key Laboratory of Energy Conversion and Energy Storage Materials Guangzhou 510006People’s Republic of China

Porous organic cages(POCs)with permanent porosity and excellent host–guest property hold great potentials in regulating ion transport behavior,yet their feasibility as solid-state electrolytes has never been testified in a practical ***,we design and fabricate a quasi-solid-state electrolyte(QSSE)based on a POC to enable the stable operation of Li-metal batteries(LMBs).Benefiting from the ordered channels and cavity-induced anion-trapping effect of POC,the resulting POC-based QSSE exhibits a high Li+transference number of 0.67 and a high ionic conductivity of 1.25×10^(−4) S cm^(−1) with a low activation energy of 0.17 *** allow for homogeneous Li deposition and highly reversible Li plating/stripping for over 2000 *** a proof of concept,the LMB assembled with POC-based QSSE demonstrates extremely stable cycling performance with 85%capacity retention after 1000 ***,our work demonstrates the practical applicability of POC as SSEs for LMBs and could be extended to other energy-storage systems,such as Na and K batteries.

关键词： Porous organic cage Cavity-induced anion-trapping Quasi-solid-state electrolyte Homogeneous Li+flux Lithium metal battery

Activin A receptor type 1C single nucleotide polymorphisms associated with esophageal squamous cell carcinoma risk in Chinese population

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Oncology 2025年第1期17卷 39-51页

作者： Si-Yun Lin Hou Huang Jin-Jie Yu Feng su Tian Jiang Shao-Yuan Zhang Lu Lv Tao Long Hui-wen Pan Jun-Qing Qi Qiang Zhou Wei-Feng Tang Guo-wen Ding Li-Ming Wang Li-Jie Tan Jun yin Department of Thoracic surgery Zhongshan Hospital Affiliated to Fudan UniversityShanghai 200032China Shanghai Key Laboratory of Clinical Geriatric Medicine Huadong Hospital Affiliated to Fudan UniversityShanghai 200040China Department of Cardiothoracic surgery The Affiliated People's Hospital of Jiangsu UniversityZhenjiang 212002Jiangsu ProvinceChina Department of Thoracic surgery Sichuan Cancer Hospital&InstituteChengdu 610042Sichuan ProvinceChina Department of Cardiothoracic surgery Nanjing Drum Tower HospitalThe Affiliated Hospital of Nanjing University Medical SchoolNanjing 210000Jiangsu ProvinceChina Department of Respiratory and Critical Care Medicine Shanghai Xuhui Central HospitalShanghai 200032China

BACKGROUND Transforming growth factor-β(TGF-β)superfamily plays an important role in tumor progression and *** A receptor type 1C(ACVR1C)is a TGF-βtype I receptor that is involved in tumorigenesis through binding to dif-ferent *** To evaluate the correlation between single nucleotide polymorphisms(SNPs)of ACVR1C and susceptibility to esophageal squamous cell carcinoma(ESCC)in Chinese Han *** In this hospital-based cohort study,1043 ESCC patients and 1143 healthy controls were *** SNPs(rs4664229,rs4556933,rs77886248,rs77263459,rs6734630)of ACVR1C were assessed by the ligation detection reaction ***-Weinberg equilibrium test,genetic model analysis,stratified analysis,linkage disequi-librium test,and haplotype analysis were *** Participants carrying ACVR1C rs4556933 GA mutant had significantly decreased risk of ESCC,and those with rs77886248 TA mutant were related with higher risk,especially in older male *** the haplotype analysis,ACVR1C Trs4664229Ars4556933Trs77886248Crs77263459Ars6734630 increased risk of ESCC,while Trs4664229Grs4556933Trs77886248Crs77263459Ars6734630 was associated with lower susceptibility to *** ACVR1C rs4556933 and rs77886248 SNPs were associated with the susceptibility to ESCC,which could provide a potential target for early diagnosis and treatment of ESCC in Chinese Han population.

关键词： Activin A receptor type 1C Single nucleotide polymorphisms Esophageal squamous cell carcinoma Genetic susceptibility Hospital-based cohort study

Glucocorticoid receptor signaling in the brain and its involvement in cognitive function

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第9期20卷 2520-2537页

作者： Chonglin su Taiqi Huang Meiyu Zhang Yanyu Zhang Yan Zeng Xingxing Chen Brain Science and Advanced Technology Institute Hubei Province Key Laboratory of Occupational Hazard Identification and ControlSchool of MedicineWuhan University of Science and TechnologyWuhanHubei ProvinceChina

The hypothalamic-pituitary-adrenal axis regulates the secretion of glucoco rticoids in response to environmental *** the brain,a nuclear receptor transcription fa ctor,the glucocorticoid recepto r,is an important component of the hypothalamicpituitary-a d renal axis's negative feedback loop and plays a key role in regulating cognitive equilibrium and *** glucoco rticoid receptor influences cognitive processes,including glutamate neurotransmission,calcium signaling,and the activation of brain-derived neurotrophic factor-mediated pathways,through a combination of genomic and non-genomic *** interactions within the central nervous system can alter the expression and activity of the glucocorticoid receptor,there by affecting the hypothalamic-pituitary-a d renal axis and stress-related cognitive *** appropriate level of glucocorticoid receptor expression can improve cognitive function,while excessive glucocorticoid receptors or long-term exposure to glucoco rticoids may lead to cognitive *** with cognitive impairment-associated diseases,such as Alzheimer's disease,aging,depression,Parkinson's disease,Huntington's disease,stroke,and addiction,often present with dysregulation of the hypothalamic-pituitary-adrenal axis and glucocorticoid receptor *** review provides a comprehensive overview of the functions of the glucoco rticoid receptor in the hypothalamic-pituitary-a d renal axis and cognitive *** emphasizes that appropriate glucocorticoid receptor signaling fa cilitates learning and memory,while its dysregulation can lead to cognitive *** provides clues about how glucocorticoid receptor signaling can be targeted to ove rcome cognitive disability-related disorders.

关键词： brain-derived neurotrophic factor calcium signaling glucocorticoid receptor glucocorticoid glutamate transmission hypothalamic-pituitary-adrenal axis long-term potentiation neurocognitive disorders neuroplasticity stress

2013年都匀市王司镇土源性线虫监测结果分析

在线全文

学校读者我要写书评

暂无评论

现代预防医学 2015年第3期42卷 540-541+568页

作者：张琪裔苏文谭向新张应宣张利罗宇玲贵州省都匀市疾病预防控制中心

目的了解都匀市王司镇人群土源性线虫感染状况,为制定土源性线虫防治策略及措施提供科学依据。方法按照《贵州省土源性线虫病监测方案（2013）》要求,选取检测点及监测人群,对资料进行统计学分析。结果土源性线虫总感染率为24.6%,其中,... 详细信息

目的了解都匀市王司镇人群土源性线虫感染状况,为制定土源性线虫防治策略及措施提供科学依据。方法按照《贵州省土源性线虫病监测方案（2013）》要求,选取检测点及监测人群,对资料进行统计学分析。结果土源性线虫总感染率为24.6%,其中,蛔虫、钩虫、鞭虫感染率分别为23.8%、0.8%、0.4%。对3;2岁儿童进行检查,未发现蛲虫感染。共监测10户人家,采集菜园、厕所周边、庭院、厨房四类地点的土样共计40份,每类土壤样品中均检出蛔虫卵,检测率为40%。结论本次监测发现蛔虫、钩虫、鞭虫感染,蛔虫为主要感染虫种,感染率为23.8%,以轻度感染为主。四类土壤蛔虫检出率40%,都匀市王司镇土源性线虫感染源普遍存在,应采取健康教育、粪便无害化处理、改水改厕及肠道驱虫为一体的综合防治措施。

关键词：土源性线虫监测感染率对策