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铜绿假单胞菌对食品中沙门氏菌检测干扰作用的评价

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食品安全质量检测学报 2016年第7期7卷 2645-2651页

作者：李琼琼杨燕范一灵杨美成上海市食品药品检验所上海201203

目的评价铜绿假单胞菌作为干扰菌对食品中沙门氏菌准确检出的影响。方法在无菌奶粉样品中人工污染不同浓度的沙门氏菌（1-100 CFU/10 g）和铜绿假单胞菌（0-10-6 CFU/10 g）,参照GB4789.4-2010进行检测,同时利用全自动酶联免疫检测系统... 详细信息

目的评价铜绿假单胞菌作为干扰菌对食品中沙门氏菌准确检出的影响。方法在无菌奶粉样品中人工污染不同浓度的沙门氏菌（1-100 CFU/10 g）和铜绿假单胞菌（0-10-6 CFU/10 g）,参照GB4789.4-2010进行检测,同时利用全自动酶联免疫检测系统（VIDAS30）和全自动病原微生物检测系统（BAX Q7 System）对样品进行快速筛查,以此综合评价铜绿假单胞菌作为干扰菌对沙门氏菌检测过程的影响。结果在不同浓度的铜绿假单胞菌干扰下,VIDAS和BAX系统均能够准确筛查出沙门氏菌阳性样品;使用的3种选择性平板对沙门氏菌和铜绿假单胞菌的分离效果存在差异,XLD平板优于BS平板和科玛嘉CAS平板,其中铜绿假单胞菌和沙门氏菌在科玛嘉CAS平板上具有相似的显色情况,直接影响沙门氏菌的检测结果;BPW前增菌8 h沙门氏菌的平板分离效果优于前增菌18 h。结论研究表明,铜绿假单胞菌在选择性平板分离步骤时对沙门氏菌具有干扰作用。联合使用2种以上沙门氏菌选择培养基,才能保证沙门氏菌的准确检出。VIDAS和BAX可作为沙门氏菌快速筛查的可靠技术手段。

关键词：沙门氏菌铜绿假单胞菌干扰作用

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企业技术创新过程中的虚拟价值链分析

技术与创新管理 2011年第2期32卷 108-110,120页

作者：马秀君樊一阳廖雅上海理工大学管理学院上海200093

随着高新科技的发展、网络的普及以及全球信息化时代的到来,信息技术、网络技术和集成技术等为主导的、与实体市场平行的虚拟市场正逐渐覆盖着全球商业市场的每个角落,文章通过分析虚拟价值链这一判断竞争优势并发现一些方法以创造和维... 详细信息

随着高新科技的发展、网络的普及以及全球信息化时代的到来,信息技术、网络技术和集成技术等为主导的、与实体市场平行的虚拟市场正逐渐覆盖着全球商业市场的每个角落,文章通过分析虚拟价值链这一判断竞争优势并发现一些方法以创造和维持竞争优势的基本工具来确定企业的创新源泉,并发现企业价值的增值,针对创新源进行技术创新,从而构建企业持续的成本领先优势和差异化优势。

关键词：技术创新虚拟价值链,竞争优势

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基于审计的技术创新管理研究

技术与创新管理 2010年第5期31卷 522-526页

作者：廖雅樊一阳陈亚锋上海理工大学管理学院上海200090 上海理工大学医疗器械与食品学院上海200090

随着市场竞争的日益激烈,技术创新的重要性日益凸显,加强技术创新管理有效性的要求也日渐突出。对技术创新活动实施审计是技术创新管理的一大创新。通过对技术创新管理的现状分析,提出了技术创新审计的完整概念,并采用系统工程法,建立... 详细信息

随着市场竞争的日益激烈,技术创新的重要性日益凸显,加强技术创新管理有效性的要求也日渐突出。对技术创新活动实施审计是技术创新管理的一大创新。通过对技术创新管理的现状分析,提出了技术创新审计的完整概念,并采用系统工程法,建立技术创新审计的概念模型。在细分技术创新过程中的各级利益相关者的基础上,给出了企业在推行技术创新审计时的工作流程和一般方法。

关键词：创新管理创新审计利益相关者

A Better Semi-online Algorithm for Q3/s_1=s_2≤s_3/C_(min) with the Known Largest Size

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Acta Mathematicae Applicatae Sinica 2012年第1期28卷 111-116页

作者： Sheng-yi CAI Qi-fan yang Department of Mathematics Zhejiang UniversityHangzhou 310027China School of Mathematics&Information Science Wenzhou UniversityWenzhou 325035China

This paper investigates the semi-online machine covering problem on three special uniform machines with the known largest size. Denote by sj the speed of each machine, j = 1, 2, 3. Assume 0 〈 s1 = s2 = r 〈 t = s3, and let s = t/r be the speed ratio. An algorithm with competitive ratio max（2, 3s＋6/s＋6 is presented. We also show the lower bound is at least max（2, 38 3s/s＋6）. For s ≤ 6, the algorithm is an optimal algorithm with the competitive ratio 2. Besides, its overall competitive ratio is 3 which matches the overall lower bound. The algorithm and the lower bound in this paper improve the results of Luo and Sun.

关键词： analysis of algorithms scheduling machine covering semi-online competitive ratio

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绵阳市男男性行为人群流动性行为及影响因素

中国公共卫生 2017年第3期33卷 345-349页

作者：王毅樊静杨晓玲刘江杨干金李伟贾秀伟任延飞笪旭辉王洪明绵阳市疾病预防控制中心性病艾滋病防治所四川绵阳621000 绵阳同志关爱小组绵阳市涪城区疾病预防控制中心江油市疾病预防控制中心三台县疾病预防控制中心安县疾病预防控制中心北川羌族自治县疾病预防控制中心盐亭县疾病预防控制中心绵阳市游仙区疾病预防控制中心梓潼县疾病预防控制中心

目的了解四川省绵阳市男男性行为人群(MSM)流动性行为现状及影响因素。方法 2014年4—10月,以四川省绵阳市辖MSM为对象,应用滚雪球抽样法,在固定场所进行调查对象招募和自填式匿名行为及血清学调查。结果有效问卷1 051份,流动性行为占16... 详细信息

目的了解四川省绵阳市男男性行为人群(MSM)流动性行为现状及影响因素。方法 2014年4—10月,以四川省绵阳市辖MSM为对象,应用滚雪球抽样法,在固定场所进行调查对象招募和自填式匿名行为及血清学调查。结果有效问卷1 051份,流动性行为占16.7%(175/1 051),不同地区差异有统计学意义(χ~2=274.330,P=0.000)。流动性行为中,去附近县占29.9%(52/175)、去绵阳城区占60.0%(105/175)、去成都占8.6%(15/175)、去其他地区占1.7%(3/175)。多因素分析,年龄、文化程度、本地居住时间、认识当地MSM朋友数、预防服务、寻找性伴场所、近1周肛交次数是流动性行为的独立影响因素(均P<0.05)。结论 MSM流动性行为具有一定人口学、地区和场所特性,其高频率性行为增大了艾滋病病毒(HIV)的感染风险和跨区域传播,应针对性加大行为干预。

关键词：男男性行为人群(MSM) 流动性行为艾滋病影响因素

Investigating jet physical properties of Fermi blazars with broad-line emissions

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Science China(Physics,Mechanics & Astronomy) 2023年第10期66卷 138-154页

作者： Lixia Zhang Jianghe yang yi Liu Junhui fan Center for Astrophysics Guangzhou UniversityGuangzhou 51006China Astronomy Science and Technology Research Laboratory of Department of Education of Guangdong Province Guangzhou 510006China Key Laboratory for Astronomical Observation and Technology of Guangzhou Guangzhou 510006China Great Bay Center National Astronomical Data CenterGuangzhou 510006China Department of Physics and Electronics Science Hunan University of Arts and ScienceChangde 415000China

Relativistic outflows often exhibit extreme observational characteristics due to beaming effects, which makes measuring their jet power a challenging task. Although the spectral energy distribution(SED) obtained from multi-wavelength data can constrain the physical parameters of these jets, accurately estimating the Doppler factor remains difficult. To address this challenge, we assemble a comprehensive sample containing available SEDs of synchrotron and inverse Compton(IC) components, monochromatic luminosity, and broad-line region(BLR) emissions. We employ a parabolic equation to fit the synchrotron radiation SEDs,constraining jet physical parameters within the framework of a one-zone leptonic model. Our study delves into the jet properties and Doppler factor estimations, yielding the following key findings:(1) The fitting results of SED data for the entire sample reveal normal distributions of jet physical parameters for two subclasses of blazars.(2) Correlation analysis demonstrates that synchrotron peak luminosity exhibits a proportional relationship with both the radio and the γ-ray luminosities.(3) We introduce a novel method for estimating Doppler factors, which uncovers discrepancies between Doppler factors from this work and others from different techniques.

关键词： active galactic nuclei blazars jets spectral energy distribution

Effect of yttrium addition on microstructure, mechanical and corrosion properties of 20Cr13 martensitic stainless steel

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Journal of Iron and Steel Research International 2020年第4期27卷 451-460页

作者： Qi-yu Zang yang-fan Jin Tuo Zhang yi-tao yang School of Materials Science and Engineering Shanghai UniversityShanghai 200444China

The effects of rare-earth yttrium(Y)element on the microstructure,mechanical properties and corrosion properties of 20Cr13 martensitic stainless steel were investigated by optical microscopy,scanning electron microscopy and tensile *** experiments were carried out to study the effect of rare-earth element Y addition on corrosion *** results showed that the addition of 0.02 wt.%rare-earth yttrium to martensitic stainless steel could affect the microstructure transformation,and Ac3 temperature was obviously *** the stainless steel after heat treatment,there were more pro-eutectoid ferrite in the steel with 0.02 wt.%*** mechanical test results showed that the addition of 0.02 wt.%yttrium could significantly improve the tensile strength and elongation of the steel,which was related to the influence of yttrium element on inclusions in the test *** the quenching temperature of 0.02 wt.%yttrium steel increasing,the content of the ferrite in steel was affected and the corrosion resistance was remarkably improved.

关键词： Yttrium Martensitic stainless steel Mechanical property Microstructural characterization Corrosion

Identification of a four-miRNA signature predicts the prognosis of papillary thyroid cancer

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World Journal of Clinical Cases 2023年第1期11卷 92-103页

作者： fan yang yi-Li Zhou Department of Thyroid Surgery The First Affiliated Hospital of Wenzhou Medical UniversityWenzhou 325000Zhejiang ProvinceChina

BACKGROUND In recently diagnosed patients with thyroid cancer,papillary thyroid cancer(PTC),as the most common histological subtype,accounts for 90%of all *** PTC is known as a relatively adolescent malignant disease,there still is a high possibility of recurrence in PTC patients with a poor ***,new biomarkers are necessary to guide more effective stratification of PTC patients and personalize therapy to avoid overtreatment or inadequate *** evidence demonstrates that microRNAs(miRNAs)have broad application prospects as diagnostic biomarkers in *** To explore novel markers consisting of miRNA-associated signatures for PTC *** We obtained and analyzed the data of 497 PTC patients from The Cancer Genome *** patients were randomly assigned to either a training or testing *** We discovered 237 differentially expressed miRNAs in tumorous thyroid tissues compared with normal tissues,which contained 172 up-regulated and 65 downregulated *** evaluation of differently expressed miRNAs was conducted using our risk score *** then successfully generated a fourmiRNA potential prognostic signature[risk score=(-0.001×hsa-miR-181a-2-3p)+(0.003×hsa-miR-138-5p)+(-0.018×hsa-miR-424-3p)+(0.284×hsa-miR-612)],which reliably distinguished patients from high and low risk with a significant difference in the overall survival(P<0.01)and was effective in predicting the five-year disease survival rate with the area under the receiver operating characteristic curve of 0.937 and 0.812 in the training and testing cohorts,***,there was a trend indicated that high-risk patients had shorter relapse-free survival,although statistical significance was not reached(P=0.082)in our sequencing *** Our results indicated a four-miRNA signature that has a robust predictive effect on the prognosis of ***,we would recommend more radical therapy and closer follow-u

关键词： Papillary thyroid cancer microRNA Prognosis Signature

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“三个代表”重要思想与科学的教育发展观

湛江海洋大学学报 2004年第5期24卷 1-6页

作者：苏一凡杨经铭湛江海洋大学广东湛江524088

解决教育发展问题必须从“三个代表”的高度树立和落实科学的教育发展观 ,促进教育事业全面协调可持续发展。这就要科学把握“三个代表”重要思想与科学的教育发展观之关系 ,尊重教育的内、外部规律 ,落实好十六大报告提出的贯彻“三个... 详细信息

解决教育发展问题必须从“三个代表”的高度树立和落实科学的教育发展观 ,促进教育事业全面协调可持续发展。这就要科学把握“三个代表”重要思想与科学的教育发展观之关系 ,尊重教育的内、外部规律 ,落实好十六大报告提出的贯彻“三个代表”重要思想的“四个必须”。

关键词： “三个代表”重要思想科学发展观教育发展观