检索结果-南通市图书馆

Journal of Zhejiang University-Science C(Computers and Electronics) 2011年第5期12卷 436-442页

作者： Bin LIN Xiao-lang YAN Zheng SHI yi-wei yang Institute of VLSI Design Zhejiang University Hangzhou 310027 China

Optical proximity correction (OPC) is a key step in modern integrated circuit (IC) *** quality of model-based OPC (MB-OPC) is directly determined by segment offsets after OPC ***,in conventional MB-OPC,the intensity of a control site is adjusted only by the movement of its corresponding segment;this scheme is no longer accurate enough as the lithography process *** the other hand,matrix MB-OPC is too time-consuming to become *** this paper,we propose a new sparse matrix MB-OPC algorithm with model-based mapping between segments and control *** put forward the concept of 'sensitive area'.When the Jacobian matrix used in the matrix MB-OPC is evaluated,only the elements that correspond to the segments in the sensitive area of every control site need to be calculated,while the others can be set to *** new algorithm can effectively improve the sparsity of the Jacobian matrix,and hence reduce the *** theoretical analysis and experiments show that the sparse matrix MB-OPC with model-based mapping is more accurate than conventional MB-OPC,and much faster than matrix MB-OPC while maintaining high accuracy.

关键词： Matrix sparsity Optical proximity correction (OPC) Convergence Segment Sensitive area

Solvothermal Synthesis and Crystal Structure of Zn(en)_3B_5O_7(OH)_3

在线全文

学校读者我要写书评

暂无评论

Chemical Research in Chinese Universities 2006年第3期22卷 271-273页

作者： HE yi CHEN wei yang Jin XI Chun-yu CHEN Jie-sheng State Key Laboratory of Inorganic Synthesis and Preparative Chemistry College of Chemistry Jilin University Changchun 130012 P. R. China

A new polyborate containing ehiral metal-complex Zn（en）3 B5O7（OH）3, where en = ethylenediamine, was synthesizedunder solvothermal conditions and structurally characterized by means of X-ray diffraction analysis. Crystal data： Zn（en）3 B5O7（OH）3, monoclinic, space group P21/c, a =0.8532（72） nm, b =2.3340（5） nm, c = 0.9526（92） nm, β =107. 04（3）°, Z=4, V=1.8140（6） nm^3, Dc =1.694 g/cm^3, p=1.416 mm^-1, F（000） = 960, GOF = 1. 020, R =0. 0276, Rw =0. 0828. There is a chiral Zn（en）3^2＋ complex cation and an isolated B5O7（OH）3^2- group in a Zn（en）3 B5O7（OH）3 molecule. The enantiomer of the chiral complex cation is separated orderly as ,4 and A configurations in the compound and the borate group consists of two B303 cycles linked through a bridging boron atom.

关键词： Solvothermal synthesis Crystal structure Chiral metal-complex Borate compound

Prognostic factors in Chinese patients with metastatic castration-resistant prostate cancer treated with docetaxel-based chemotherapy

在线全文

学校读者我要写书评

暂无评论

Asian Journal of Andrology 2013年第1期15卷 110-115页

作者： Yuan-Yuan Qu Bo Dai Yun-yi Kong Ding-wei Ye Xu-Dong Yao Shi-Lin Zhang Hai-Liang Zhang Chun-Guang Ma wei-yi yang Department of Urology Fudan University Shanghai Cancer Center Shanghai 200032 China Department of Oncology Fudan University Shanghai Medical College Shanghai 200032 China Department of Pathology Fudan University Shanghai Cancer Center Shanghai 200032 China

This study aims to evaluate the potential value of patient characteristics in predicting overall survival （OS） in patients with metastatic castration-resistant prostate cancer （mCRPC） treated with docetaxel-based thermotherapy. A total of 115 patients with mCRPC undergoing a docetaxel q3w regimen were enrolled in this study. A survival analysis was performed using the Kaplan-Meier method. Cox proportional hazards models were used to evaluate the prognostic value of all covariates for OS. OS was also analysed after stratifying patients according to the results of multivariate analysis. The median OS for the entire cohort was 17.0 months. The multivariate analysis showed that the prostate-specific antigen doubling time （PSADT）, baseline haemoglobin （Hb） concentration, alkaline phosphatase （ALP） concentration, cycles of chemotherapy and time to castration resistance were independent prognostic factors of OS. According to the presence of PSADT 〈46.3 days and baseline ALP/〉 110 IU 1-1, all patients were divided into three risk groups： low-risk group （no risk factors）, intermediate-risk group （one risk factor） and high-risk group （two risk factors）. Median OSs for patients in low-, intermediate- and high-risk groups were 28.0 months （95% Ch 23.8-32.2）, 21.0 months （95% Ch 18.9-23.1） and 11.0 months （95% Ch 7.6-14.4）, respectively （P〈O.O01）. In conclusion, PSADT, baseline Hb concentration, ALP concentration, cycles of chemotherapy and time to castration resistance were independent prognostic factors of OS in Chinese patients with mCRPC treated with docetaxel. PSADT combined with the baseline ALP concentration could be a useful risk stratification parameter for evaluating survival outcomes.

关键词： castration-resistant docetaxel metastatic overall survival prognostic factor prostate cancer

Synthesis and Crystal Structure of a Hexameric Organooxotin Cluster from Benzilic Acid

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Structural Chemistry 2005年第11期24卷 1249-1253页

作者： CHEN Man-Sheng KUANG Dai-Zhi ZHANG Chun-Hua DENG yi-Fang LI wei yang ying-Qun Department of Chemistry and Material Science Hengyang Normal University Hengyang 421008 China

The title complex [^n BuSn（O）O2C（OH）CPh2]6.2H2O has been synthesized by the reaction of n-BuSn（O）OH with benzilic acid in 1：1 molar radio and characterized by IR, ^1H NMR spectra and elemental analysis. The crystal structure was determined by X-ray diffraction. It crystallizes in triclinic, space group PI with a = 1.3543（2）, b = 1.4593（2）, c = 1.5293（2） nm, α = 102.075 （2）,β = 115.571 （2）, γ = 93.308（3）°, Z = 1, V = 2.6282（7） nm^3, Mr = 2550.21, Dc = 1.611 g/cm^3,μ = 1.477 mm^-1, F（000） = 1280, R = 0.0309 and wR = 0.0729. The structure shows a distorted octahedral configuration with six-coordination for the central tin atom.

关键词： organooxotin cluster benzilic acid crystal structure synthesis organooxotin cluster benzilic acid crystal structure synthesis

Clinical Characteristics and Treatment of Spontaneous Osteonecrosis of Medial Tibial Plateau： A Retrospective Case Study

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2018年第21期131卷 2544-2550页

作者： wei-Ming yang Cai-Qiong Zhao Zhao-Yu Lu wei-yi yang Ding-Kun Lin Xue-wei Cao Department of Orthopaedics Guangdong Provincial Hospital of Chinese Medicine The Second Affiliated Hospital of Guangzhou University of Chinese Medicine Guangzhou Guangdong 510120 China Guangdong Provincial Academy of Chinese Medical Sciences Guangdong Provincial Hospital of Chinese Medicine Guangzhou Guangdong 510120 China

Background： In a small proportion of cases, spontaneous osteonecrosis of the knee （SONK） involves the medial tibial plateau （MT）. Here, we introduced the clinical characteristics of spontaneous osteonecrosis of the MT and unicompartmental knee arthroplasty （UKA） as the favorable treatment for this situation based on a retrospective case study. Methods： Patients with spontaneous osteonecrosis of the MT, confirmed by magnetic resonance imaging （MRI） at Guangdong Provincial Hospital of Chinese Medicine （China） from March 2015 to June 2016, were included as a case serial and analyzed retrospectively. All patients underwent Oxford Medial UKA. The characteristics of their lesions, corresponding treatment, and results of follow-up were presented. The lesion scores and grade were determined according to the criteria of Ficat and Arlet. Results： In total, 22 patients （5 men, 17 women： mean age, 64.1 years） with spontaneous osteonecrosis of the MT were analyzed. The lesion stages assessment showed that 3 （14%） were Stage 11, 10 （45%） were Stage Ⅲ, 7 （32%） were Stage IV, and 2 （9%） were Stage V. In the sagittal plane, 7 （32%） were in the anterior region （MTa） and 15 （68%） were central （MTc）. The lesion volume averaged 2.24 ± 0.79 cm3 （range： 1.57-3.08 cm3）. Seventeen patients （77%） had Level Ⅲ posterior medial meniscus root tears （MM RTs）. All the patients underwent UKA. Average follow-up was 30.0 ± 6.4 months with a range of 23.0-38.0 months. The visual analog scale score was 7.78 ± 0.67 belbre surgery while decreased to 2.22 ± 1.09 at the final follow-up （P 〈 0.001 ）. The Hospital for Special Surgery scores of pre-/post-surgery were 65.67 ± 5.45 and 84.10 ± 4.20, respectively （P 〈 0.001 ）. Conclusions： SONK often occurs in the anterior and central tibial plateau due to abnormal stresses. Most of the patients had Level Ⅲ posterior medial meniscus root tears. MRI is recommended for suspected cases to identity SONK at an early stage. The use of the Oxford Medial UKA for SONK of

关键词： Knee: Spontaneous Osteonecrosis Unicompartmental Knee Arthroplasty

Differences in Liver Injury and Trophoblastic Mitochondrial Damage in Different Preeclampsia-like Mouse Models

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2015年第12期128卷 1627-1635页

作者： yi-wei Han Zi yang Xiao-Yan Ding Huan Yu Department of Obstetrics and Gynecology Peking University Third Hospital Beijing 100191 China

Background：Preeclampsia is a multifactorial disease during *** lipid metabolism may be related to some *** investigated the relationship between triglycerides （TGs） and liver injury in different preeclampsia-like mouse models and their potential common ***：Preeclampsia-like models （Nw-nitro-L-arginine-methyl ester [L-NAME],lipopolysaccharide [LPS],apolipoprotein C-Ⅲ [Apo] transgnic mice ＋ L-NAME,β2 glycoprotein Ⅰ [βGPI]） were used in four experimental groups：L-NAME （LN）,LPS,Apo-LN and βGPI,respectively,and controls received saline （LN-C,LPS-C,Apo-C,βGPI-C）.The first three models were established in preimplantation （PI）,early-,mid-and late-gestation （EG,MG and LG）.βGPI and controls were injected before *** arterial pressure （MAP）,24-hour urine protein,placental and fetal weight,serum TGs,total cholesterol （TC） and pathologic liver and trophocyte changes were ***：MAP and proteinuria were significantly increased in the experimental *** and fetal weight in PI,EP and MP subgroups were significantly lower than *** TGs significantly increased in most groups but *** was not different between experimental and control *** hepatic cell necrosis was observed in PI,EG,MG in LN,Apo-LN and βGPI,but no morphologic changes were observed in the LPS *** trophoblastic mitochondrial damage was observed in every experimental ***：Earlier preeclampsia onset causes a higher MAP and urine protein level,and more severe placental and fetal ***-like models generated by varied means lead to different changes in lipid metabolism and associated with liver *** mitochondrial damage may be the common terminal pathway in different preeclampsia-like models.

关键词： Liver Mitochondria Preeclampsia Triglyceride Trophoblast

A modified technique of bone grafting pedicled with femoral quadratus for alcohol-induced osteonecrosis of the femoral head

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2010年第20期123卷 2847-2852页

作者： WANG yi-sheng ZHANG yi LI Jun-wei yang Guo-hui LI Jin-feng yang Jie yang Guang-hui Department of Orthopedic Surgery First Affiliated Hospital of Zhengzhou UniversityZhengzhouHenan 450052China

Background Quadratus femoris pedicled bone grafting has yielded satisfactory long-term clinical outcome for osteonecrosis of the femoral head （ONFH） in pre-collapse ONFH without extensive lesion. However, for pre-collapse ONFH with extensive necrotic area, it is still challenging to preserve the femoral head. The current study aimed to introduce a new technique of deliquesce strut with titanium mesh containing bone grafting pedicled with the femoral quadratus and to evaluate its short-term *** From January 2008 to December 2008, 10 ONFH patients （12 hips） underwent operations by a new technique of deliquesce strut with titanium mesh containing bone grafting pedicled with the femoral quadratus （group A）.According to the ARCO classification system, there were two hips in stage Ⅱ B and 10 hips in stage Ⅱ C. Also in the same period, 12 ONFH patients （16 hips） underwent operations by the conventional procedure of quadratus femoris pedicled bone grafting （group B）. There were 6 hips in stage Ⅱ B and 10 hips in stage Ⅱ C. All patients were males and suffered from alcohol induced ONFH. For the new technique, the necrotic area was evaluated, and a titanium mesh piece of the same size （range from 2.5 cm×2.8 cm to 2.8 cm×3.4 cm） was obtained and shaped to match the contour of the head. The cancellous bone was first placed underneath the subchondral bone and was densely impacted （about 1 to 2 mm thick）.Then the titanium mesh piece was inserted. The length of the decompressive trough was measured. A titanium cylinder mesh cage with a diameter of 1.6 cm of the same length was obtained, with a ＂U＂ shaped window in the wall being created to make room for the muscle pedicle. The muscle pedicle bone was inserted into the titanium mesh cage to form a bone graft-titanium cage complex and, then the complex was inserted. The hundred percent score method was used for outcome evaluation. Clinical and radiographic outcomes were compared between group A and group *** The a

关键词： osteonecrosis of femoral head titanium mesh pedicled with quadratus femoris strut bone grafting deliquesce prop

Influence of obesity on localized prostate cancer patients Ireated with radical prostatectomy

在线全文

学校读者我要写书评

暂无评论

Asian Journal of Andrology 2013年第6期15卷 747-752,I0006页

作者： Yuan-Yuan Qu Bo Dai Yun-yi Kong Kun Chang Ding-wei Ye Xu-Dong Yao Shi-Lin Zhang Hai-Liang Zhang wei-yi yang Department of Urology Fudan University Shanghai Cancer Center Shanghai 200032 China Department of Oncology Fudan University Shanghai Medical College Shanghai 200032 China Department of Pathology Fudan University Shanghai Cancer Center Shanghai 200032 China

This study aimed to investigate the association between different anthropometric measures of obesity and clinicopathological characteristics in Chinese patients with clinically localized prostate cancer （PCa）. A total of 734 patients with clinically localized PCa who underwent radical prostatectomy （RP） were included in this study. Clinical and pathological data from each patient were collected. Anthropometric measures of abdominal adiposity were measured from T2-weighted sagittal Iocalisation images from magnetic resonance imaging （MRI） for 413 （56.3%） patients. Patient clinical and pathological characteristics were compared across body mass index （BMI） groups. Univariable and multivariable logistic regression models were used to address the influence of the preoperative total testosterone level and anthropometric measures of obesity on pathological outcomes. In the multivariate analysis, BMI was not significantly associated with any pathological outcomes. However, the percentage of visceral adipose tissue （VAT%） was an independent predictor of a pathological Gleason score ≥8 （P〈0.O01）, extracapsular extension （ECE; P=0.002） and seminal vesicle invasion （SVI; P=0.007）. More importantly, we found that the preoperative total testosterone level was significantly correlated with the VAT% （Pearson＇s correlation coefficient： -0.485, P〈0.001） and subcutaneous adipose tissue （SAT; Pearson＇s correlation coefficient： 0.413, P〈0.001）. In conclusion, the results of this study suggest that abdominal fat distribution, and particularly VAT%, is associated with a risk of advanced PCa. Moreover, our present study confirms a significant inverse correlation between visceral adiposity and testosterone. Further studies are warranted to elucidate the biological mechanisms underlying the relationship between abdominal adiposity and the aggressiveness of PCa.

关键词： body mass index (BMI) obesity prostatic nec)plasm radical prostatectomy testosterone visceral adiposity

Measurement of the neutron-induced total cross sections of ^(nat)Pb from 0.3 eV to 20 MeV on the Back-n at CSNS

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nuclear Science and Techniques 2024年第2期35卷 85-93页

作者： Jie-Ming Xue Song Feng Yong-Hao Chen Han yi Min Xiao Pin-Jing Cheng Xin-Xiang Li Rong Liu yi-wei yang Zi-Jie Han Da-Jun Zhao Hao-Qiang Wang Bao-Qian Li Ji-Rong Zhao Lei-Xun Tang Wen Luo Bo Zheng School of Nuclear Science and Technology University of South ChinaHengyang 421001China Institute of High Energy Physics Chinese Academy of Sciences(CAS)Beijing 100049China Spallation Neutron Source Science Center Dongguan 523803China Institute of Nuclear Physics and Chemistry China Academy of Engineering PhysicsMianyang 621900China

The neutron-induced total cross sections of natural lead have been measured in a wide energy range(0.3 eV-20 MeV)on the back-streaming white neutron beamline(Back-n)at the China Spallation Neutron *** energy was determined by the neutron total cross-section spectrometer using the time-of-flight technique.A fast multi-cell fission chamber was used as the neutron detector,and a 10-mm-thick high-purity natural lead sample was employed for the neutron transmission *** on-beam background was determined using Co,In,Ag,and Cd *** excitation function of ^(nat)Pb(n,tot)reaction below 20 MeV was calculated using the TALYS-1.96 nuclear-reaction modeling *** present results were compared with previous results,the evaluated data available in the five major evaluated nuclear data libraries(i.e.,ENDF/B-VIII.0,JEFF-3.3,JENDL-5,CENDL-3.2,and BROND-3.1),and the theoretical calculation *** agreement was found between the new results and those of previous experiments and with the theoretical curves in the corresponding *** measurement obtained the neutron total cross section of natural lead with good accuracy over a wide energy range and added experimental data in the resonance energy *** provides more reliable experimental data for nuclear engineering design and nuclear data evaluation of lead.

关键词： Neutron-induced total cross section Natural lead Time-of-flight TALYS-1.96 CSNS Back-n white neutron beamline

Ossicular Reconstruction with Sheehy PORP

在线全文

学校读者我要写书评

暂无评论

Journal of Otology 2009年第1期4卷 50-54页

作者： yang Shi-ming,ZOU yi-Hui,HOU Zhao-Hui,HAN Dong-yi Han,yang wei-yan Dept.Otolaryngology Head and Neck Surgery,Institute of Otolaryngology,Chinese PLA General Hospital,Beijing 100853 Dept. Otolaryngology Head and Neck Surgery Institute of Otolaryngology Chinese PLA General Hospital Beijing 100853

Objective To report tympanoplasty cases completed with Sheehy Partial Ossicular Replacement Prostheses(PORP).Methods Seventy eight(83 ears) of 89 cases who received Sheehy PORP for ossicular chain reconstructionwere *** cases were followed for more than 6 months(mean:21.3 months).The preand post -operative average air conduction thresholds and Air -Bone Gap(ABG) at 0.5,1 and 2 kHz were *** All 83 ears showed uneventful healing at 1 month *** in 2 ears without cartilage reinforcement were found dislocated at 3 *** hearing thresholds were from 35.75 to 68.5 dB HL(mean:59.13 ± 15.23 dB HL).Postoperative mean hearing threshold improved to 32.23± 13.21 dB HL(P < 0.01).Mean air-bone gap(ABG) improved from 36.95 ± 12.19 dB preoperatively to 21.71 ± 12.05 dB after surgery(P < 0.01).In 68 ears(81.9%),postoperative ABGs were either ≤ 20 dB or improved by 15 dB or more compared to before surgery(defined as satisfactory).Conclusion PORP as a ossicular reconstruction material appears to provide satisfactory *** should be paid to avoid of postoperative ***-term outcomes remain to be assessed.

关键词： Hearing reconstruction Air-Bone Gap(ABG) PORP