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Extracts from Paeonia lactiflora Pallas, Rehmannia Glutinosa var. Purpurea Makino, Perilla Frutescens var. Acuta Kudo may increase the endometrial receptivity through expression of leukemia inhibitory factor and adhesion molecules

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Journal of Traditional Chinese Medicine 2019年第1期39卷 15-25页

作者： eun-yeong kim Tae-Wook Chung Hee-Jung Choi Yeon-Seop Jung Syng-Ook Lee Jun-Yong Choi Hyung Sik kim Sooseong You Myeong Soo Lee Ki-Tae Ha School of Korean Medicine and Korean Medical Research Center for Healthy Aging Pusan National UniversityYangsan 50612Republic of Korea Graduate Training Program of Korean Medicine for Healthy-aging Pusan National UniversityYangsan 50612Republic of Korea Department of Food Science and Technology Keimyung UniversityDaegu 42601Republic of Korea National Clinical Research Center for Korean Medicine Korean Medicine Hospital of Pusan National UniversityYangsan 50612Republic of Korea Laboratory of Molecular Toxicology School of PharmacySungKyunKwan UniversitySuwon 16419Republic of Korea Korea Institute of Oriental Medicine Daejeon 34054Republic of Korea

OBJECTIVE: To find out the combination of the extracts from Paeonia lactiflora Pallas(PL), Rehmannia Glutinosa var. Purpurea Makino(RG), Perilla Frutescens var. Acuta Kudo(PF) to increase endometrial ***: Herbal medicines were extracted with boiling water and polysaccharides were *** examined the effect of PL, RG, and PF(PRP), a most effective herbal formula deduced from constitutive ingredient herbs of Antai Yin which is composed of PRP, on the leukemia inhibitory factor(LIF) expression and endometrial ***: The combination of the extracts from PRP induced the LIF expression in Ishikawa cells and increased the adhesion between Ishikawa and JAr cells. In addition, PRP-induced attachment of JAr cells onto Ishikawa cells and expression of adhesion molecules, ITGAV, ITGB5, CD44 s, and Lselectin, are significantly reduced by knock-down of LIF ***: Induced by the combination of the PRP extracts, the adhesion between trophoblast and endometrial cells are mediated by expression of LIF and adhesion molecules. Thus, we suggest the combination of the PRP extracts may be a novel therapy for enhancing embryo implantation rate.

关键词： Paeonia Rehmannia Perilla Embryo implantation Endometrium Leukemia inhibitory factor Cell adhesion molecules

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Assessment of pathogens and risk factors associated with bloodstream infection in the year after pediatric liver transplantation

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World Journal of Gastroenterology 2022年第11期28卷 1159-1171页

作者： yeong eun kim Ho Jung Choi Hye-Jin Lee Hyun Ju Oh Mi Kyoung Ahn Seak Hee Oh Jung-Man Namgoong Dae Yeon kim Won Kyoung Jhang Seong Jong Park Dong-Hwan Jung Deok Bog Moon Gi-Won Song Gil-Chun Park Tae-Yong Ha Chul-Soo Ahn Ki-Hun kim Shin Hwang Sung Gyu Lee Kyung Mo kim Department of Pediatrics Asan Medical Center Children's HospitalUniversity of Ulsan College of MedicineSeoul 05505South Korea Division of Pediatric Surgery Department of SurgeryAsan Medical Center Children's HospitalUniversity of Ulsan College of MedicineSeoul 05505South Korea Division of Hepatobiliary Surgery and Liver Transplantation Department of SurgeryAsan Medical CenterUniversity of Ulsan College of MedicineSeoul 05505South Korea

BACKGROUND Bloodstream infection(BSI)is one of the most significantly adverse events that can occur after liver transplantation(LT)in *** To analyze the profile of BSI according to the postoperative periods and assess the risk factors after pediatric *** Clinical data,collected from medical charts of children(n=378)who underwent primary LT,were retrospectively *** primary outcome considered was BSI in the first year after *** and multivariate analyses were performed to identify risk factors for BSI and respective odds ratios(ORs).RESULTS Of the examined patients,106(28%)experienced 162 episodes of pathogen-confirmed BSI during the first year after *** were 1.53±0.95 episodes per children(mean±SD)among BSIcomplicated patients with a median onset of 0.4 mo *** most common pathogenic organisms identified were Coagulase-negative staphylococci,followed by Enterococcus *** Streptococcus *** half(53%)of the BSIs were of unknown *** analysis demonstrated that young age(≤1.3 year;OR=2.1,P=0.011),growth failure(OR=2.1,P=0.045),liver support system(OR=4.2,P=0.008),and hospital stay of>44 d(OR=2.3,P=0.002)were independently associated with BSI in the year after *** BSI was frequently observed in patients after pediatric LT,affecting survival *** profile of BSI may inform clinical treatment and management in high-risk children after LT.

关键词： Bloodstream infection Liver transplantation Children Pathogens

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Optimization of an Artificial Intelligence Database and Camera Installation for Recognition of Risky Passenger Behavior in Railway Vehicles

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Computers, Materials & Continua 2025年第1期82卷 1277-1293页

作者： Min-kyeong kim yeong Geol Lee Won-Hee Park Su-hwan Yun Tae-Soon Kwon Duckhee Lee Railroad Test&Certification Division Korea Railroad Research Institute(KRRI)Cheoldo BangmulgwanroUiwang-si16105Republic of Korea Railroad Safety Division Korea Railroad Research Institute(KRRI)Cheoldo BangmulgwanroUiwang-si16105Republic of Korea

Urban railways are vital means of public transportation in *** than 30%of metropolitan residents use the railways,and this proportion is expected to *** enhance safety,the government has mandated the installation of closed-circuit televisions in all carriages by ***,cameras still monitored *** address this limitation,we developed a dataset of risk factors and a smart detection system that enables an immediate response to any abnormal behavior and intensive monitoring *** created an innovative learning dataset that takes into account seven unique risk factors specific to Korean railway *** data collection was conducted across the Shinbundang Line of the Incheon Transportation Corporation,and the Ui-Shinseol *** observed several behavioral characteristics and assigned unique annotations to *** also considered carriage *** performance was evaluated by camera placement and *** the camera installation plan was *** dataset will find immediate applications in domestic railway *** artificial intelligence algorithms will be verified shortly.

关键词： AI railway vehicle risk factor smart detection AI training data

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Effect of herbal medicines with bitter taste on the inhibition of whole blood aggregation

Effect of herbal medicines with bitter taste on the inhibiti...

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第11次中国实验血液学会议

作者： Won Kyung Jeon Sun Ok Park Bo Kyung Yoo yeong eun kim Mi Young ke Sun Min Park Byoung-Seob Ko Department of Herbal Resources Research Korea Institute of Oriental MedicineDaejeon 305-811Korea Herbal Quality Control Team Korea Institute of Oriental MedicineDaejeon 305-811Korea Herbal Quality Control Team Korea Institute of Oriental MedicineDaejeon 305-811Korea Herbal Quality Control Team Korea Institute of Oriental MedicineDaejeon 305-811Korea Herbal Quality Control Team Korea Institute of Oriental MedicineDaejeon 305-811Korea Department of Food and Nutrition Hoseo UniversityAsanChubgnam 336-795Korea Herbal Quality Control Team Korea Institute of Oriental MedicineDaejeon 305-811Korea

＜正＞For a correlation to study the Five Tastes Theory and efficacies in oriental medicine concepts,we used a traditional classified bitter taste herbal medicines and experimental *** this study,we have tested the in vitro effect of typical 20 kinds of herbal medicines with hitter taste on platelet aggregation in- duced by collagen in human whole blood using the impedance method of *** them,3 kinds of hot water extracts and 2 kinds of 70% etha-

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Role of debris flow on the change of^10Be concentration in rapidly eroding watersheds:a case study on the Seti River,central Nepal

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Journal of Mountain Science 2017年第4期14卷 716-730页

作者： kim Dong eun SEONG yeong Bae CHOI Kwang Hee YU Byung Yong Dept.of Geography Korea UniversitySeoul 02841Korea yeongsan River Basin Environmental Office Ministry of EnvironmentGwangju 61945Korea Korea Institute of Science and Technology Seoul 02792Korea

The concentration of cosmogenic loBe in riverine sediments has been widely used as a proxy for catchment-wide denudation rate （CWDR）. One of the key assumptions of this approach is that sediments originating from sub-basins with different erosional histories are well mixed. A tragic debris flow occurred in the Seti River watershed, central Nepal, on May 5, 2012. This catastrophic debris flow was triggered by slope failure on the peak of Annapurna IV and resulted in many casualties in the lower Seti Khola. However, it provided an opportunity to test the assumption of equal mixing of sediments in an understudied rapidly eroding watershed. This study documents the CWDR of ^10Be to evaluate the extent of the influence of episodic erosional processes such as debris flow on the spatio-temporal redistribution of loBe concentrations. Our data show that the debris flow caused little change in CWDR across the debris flow event. In addition to isotopic measurement, we calculated denudation rates by using the modeled concentrations in pre- and post-landslide sediments based on the local ^10Be production rate. The modeled result showed little change across the event, indicating that the debris flow in May 2012 played a minor role in sediment evacuation, despite the rapid erosion in the catchment. Our study concludes that although the 2012 event caused many casualties and severe damage, it was a low-magnitude, high frequency event.

关键词： Seti River Beryllium-10 (^10Be) Catchment-wide denudation rate (CWDR) Debrisflow Episodic erosional processes

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Installing a molecular truss beam stabilizes MOF structures

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npj Computational Materials 2022年第1期8卷 1110-1118页

作者： Hong Ki kim Jong-yeong Jung Gyumin Kang Mu-Hyun Baik eun-Young Choi Department of Chemistry Korea Advanced Institute of Science and Technology(KAIST)Daejeon34141Republic of Korea Center for Catalytic Hydrocarbon Functionalizations Institute for Basic Science(IBS)Daejeon34141Republic of Korea Korea Science Academy of KAIST 105-47 Baegyanggwanmun-roBusanjin-guBusan47162Republic of Korea

Enhancing the stability and durability of metal-organic frameworks(MOFs)is vital for practical applications because many promising MOF materials suffer from phase transitions and/or structural decompositions with humidity being a particularly damaging *** mechanical engineering,the frame of buildings and furniture can be stabilized significantly by installing a truss *** the same principle,we functionalized the organic component of MOF-5 to contain a carbazole moiety that can act as a molecular truss beam by reaching across the corner and forming a stableπ–πinteraction with a phenyl group on the edge position of the *** structural support enhanced the stability of the MOF substantially,allowing the designed MOF to maintain compositional integrity under steam conditions at 90℃for~5 *** unmodified MOF-5 shows clear signs of structural collapse after~1 h.

关键词： beam moiety durability

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Injection molding of micro patterned PMMA plate

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Transactions of Nonferrous Metals Society of China 2011年第A1期21卷 148-152页

作者： yeong-eun YOO Tae-Hoon kim Tae-Jin JE Doo-Sun CHOI Chang-Wan kim Sun-Kyung kim Department of Nanomanufacturing Technology KIMM 171 Jang-dong Yusung-gu Daejeon 305-343 Korea Department of Product Design and Manufacturing Seoul National University of Technology

A plastic plate with surface micro features was injection molded to investigate the effect of pressure rise of melt on the replication of the micro structures. Prism pattern, which is used in many optical applications, was selected as a model pattern. The prism pattern is 50 μm in pitch and 108° in the vertical angle. The overall size of the plate was 335 minx213 mm and the thickness of the plate varied linearly from 2.6 mm to 0.7 ram. The prism pattern was firstly machined on the nickel plated core block using micro diamond tool and this machined pattern core was installed in a mold for injection molding of prism patterned plate. Polymethyl methacrylate （PMMA） was used as a molding material. The pressure and temperature of the melt in the cavity were measured at different positions in the cavity and the replication of the pattern was also measured at the same positions. The results show that the pressure or temperature profile through the process depends on the shape and the size of the plate. The replication is affected by the temperature and pressure profiles at the early stage of filling, which is right after the melt reaches the position to be measured.

关键词： micro prism pattern injection molding replication pressure profile temperature profile

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High-performance MoS_(2)/p^(+)-Si heterojunction field-effect transistors by interface modulation

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Nano Research 2022年第7期15卷 6500-6506页

作者： Yoonsok kim Taeyoung kim eun Kyu kim Department of Physics and Research Institute of Natural Science Hanyang UniversitySeoul 04763Republic of Korea

Molybdenum disulfide(MoS_(2)),one of transition metal dichalcogenides,is a promising semiconductor material for electronic or optoelectronic devices due to its favorably electronic ***,in metal-oxide semiconductor field-effect transistor(MOSFET)structures using MoS_(2),electrical performances such as mobility and subthreshold swing are suppressed by the interface trap density between the channel and dielectric ***,the electrical stability of such structures is compromised due to interface traps and that can be analyzed such as current hysteresis and transient ***,we demonstrate MoS_(2) heterojunction field-effect transistors(HFET)by applying MoS_(2)/p^(+)-Si heterojunctions and achieve high performance characteristics,including a mobility of 636.19 cm^(2)/(V∙s),a subthreshold swing of 67.4 mV/dec,minimal hysteresis of 0.05 V,and minimized transient ***,the HFET devices with varying the channel length demonstrated degradation of electrical performance with increasing the overlap area of the channel and dielectric *** results regarding MoS_(2)/p^(+)-Si HFETs resulted in the structural optimization of high-performance electronic devices for practical applications.

关键词： molybdenum disulfide(MoS_(2)) transition metal dichalcogenide junction field-effect transistor dielectric layer interface trap

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Lattice design for a hybrid multi-bend achromat light source

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Nuclear Science and Techniques 2020年第7期31卷 55-64页

作者： eun-San kim Department of Accelerator Science Korea University Sejong CampusSejong 30019Korea

We present a lattice design and beam dynamics analysis for a 4 GeV low-emittance,high-brilliance synchrotron light *** lattice consisted of 26 six-bend achromats with 26 long and 26 short straight *** present the design results for a hybrid multi-bend achromat(HMBA)lattice with a natural emittance of 168 pm and circumference of 729.3 *** cell had 4 longitudinal gradient bendings,2 combined bendings,14 quadrupoles,and 2 families of *** lattice was designed to beflexible to provide both nonzero and zero dispersion functions in the long straight *** two straight sections in each cell had lengths of 5.6 and 1.2 *** ensure sufficient injection,we optimized the design lattice and dynamic *** investigated the dynamic aperture in the lattice with machine errors,and the results showed that the lattice design provides sufficient dynamic aperture after COD correction for beam *** present the results of an injection scheme that demonstrates the space in the injection section and the particle motions of the injected *** also present the results of beam tracking after the beam injection to examine the characteristics of the beam *** designed HMBA lattice was well optimized in terms of the beam parameters and brilliance as an intermediate light source at 4 GeV and a circumference of 729.3 m.

关键词： injection beam lattice

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Computational approaches for fast generation of digital 3D video holograms(Invited Paper)

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Chinese Optics Letters 2009年第12期7卷 1083-1091页

作者： Seung-Cheol kim eun-Soo kim 3D Display Research Center Department of Electronic Engineering Kwangwoon University

Several approaches for fast generation of digital holograms of a three-dimensional （3D） object have been discussed. Among them, the novel look-up table （N-LUT） method is analyzed to dramatically reduce the number of pre-calculated fringe patterns required for computation of digital holograms of a 3D object by employing a new concept of principal fringe patterns, so that problems of computational complexity and huge memory size of the conventional ray-tracing and look-up table methods have been considerably alleviated. Meanwhile, as the 3D video images have a lot of temporally or spatially redundant data in their inter- and intra-frames, computation time of the 3D video holograms could be also reduced just by removing these redundant data. Thus, a couple of computational methods for generation of 3D video holograms by combined use of the N-LUT method and data compression algorithms are also presented and discussed. Some experimental results finally reveal that by using this approach a great reduction of computation time of 3D video holograms could be achieved.

关键词： LUT Computational approaches for fast generation of digital 3D video holograms CGH

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