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Hybrid model to optimize object-based land cover classification by meta-heuristic algorithm:an example for supporting urban management in Ha Noi,Viet Nam

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International Journal of Digital Earth 2019年第10期12卷 1118-1132页

作者： Quang-Thanh Bui Manh Pham Van Nguyen thi Thuy Hang Quoc-Huy Nguyen Nguyen Xuan Linh Pham Minh hai tran Anh Tuan Pham Van Cu Center for Applied Research in Remote sensing and GIS(CARGIS) VNU University of ScienceHa NoiViet Nam VNU University of Science Ha NoiViet Nam Vietnam Institute of Geodesy and Cartography Ha NoiViet Nam Ministry of Education and Training Ha NoiViet Nam

this study proposed a novel object-based hybrid classification model named GMNN that combines Grasshopper Optimization Algorithm(GOA)and the multiple-class Neural network(MNN)for urban pattern detection in Hanoi,*** bands of SPOT 7 image and derivable NDVI,NDWI were used to generate image segments with associated attributes by PCI Geomatics *** segments were classified into four urban surface types(namely water,impervious surface,vegetation and bare soil)by the proposed ***,three training and validation datasets of different sizes were used to verify the robustness of this *** all tests,the overall accuracies of the classification were approximately 87%,and the Area under Receiver Operating Characteristic curves for each land cover type was ***,the performance of this model was examined by comparing several statistical indicators with common benchmark *** results showed that GMNN out-performed established methods in all comparable *** results suggested that our hybrid model was successfully deployed in the study area and could be used as an alternative classification method for urban land cover *** a broader sense,classification methods will be enriched with the active and fast-growing contribution of metaheuristic algorithms.

关键词： Urban remote sensing object-based classification neural network grasshopper optimization algorithm

Xanthine oxidase inhibitors from Archidendron clypearia(Jack.) I.C. Nielsen: Results from systematic screening of Vietnamese medicinal plants

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Asian Pacific Journal of Tropical Medicine 2017年第6期10卷 619-626页

作者： Nguyen Thuy Duong Pham Duc Vinh Phuong thien Thuong Nguyen thi Hoai Le Nguyen Thanh tran The Bach Nguyen hai Nam Nguyen Hoang Anh Department of Pharmacology Hanoi University of Pharmacy Department of Pharmaceutical Analysis and Standardization National Institute of Medicinal Materials Department of Pharmacognosy Hue University of Medicine and Pharmacy Institute of Marine Biochemistry Vietnam Academy of Science and Technology Institute of Ecology and Biological Resources Vietnam Academy of Science and Technology Department of Medicinal Chemistry Hanoi University of Pharmacy

Objective: To screen Vietnamese medicinal plants for xanthine oxidase(XO) inhibitory activity and to isolate XO inhibitor(s) from the most active plant. Methods: The plants materials were extracted by methanol. The active plant materials were fractionated using different organic solvents, including n-hexane, ethyl acetate, and n-butanol. Bioassay-guided fractionation and column chromatography were used to isolate compounds. The compounds structures were elucidated by analysis of spectroscopic data, including IR, MS, and NMR. Results: Three hundreds and eleven methanol extracts(CME) belonging to 301 Vietnamese herbs were screened for XO inhibitory activity. Among these plants, 57 extracts displayed XO inhibitory activity at 100 μg/m L with inhibition rates of over 50%. The extracts of Archidendron clypearia, Smilax poilanei, Linociera ramiflora and Passiflora foetida exhibited the greatest potency with IC_(50) values below 30 μg/m L. Chemical study performed on the extract of Archidendron clypearia resulted in the isolation of six compounds, including 1-octacosanol, docosenoic acid, daucosterol, methyl gallate, quercitrin and(-)-7-O-galloyltricetiflavan. The compound(-)-7-O-galloyltricetiflavan showed the most potent XO inhibitory activity with an IC_(50) value of 25.5 μmol/L. Conclusions: From this investigation, four Vietnamese medicinal plants were identified to have XO inhibitory effects with IC_(50) values of the methanol extracts below 30 μg/m L. Compound(-)-7-O-galloyltricetiflavan was identified as an XO inhibitor from Archidendron clypearia with IC_(50) value of 25.5 μmol/L.

关键词： Xanthine oxidase Inhibitor Medicinal plants Vietnam

Antidiabetic and antioxidant activities of red seaweed Laurencia dendroidea

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Asian Pacific Journal of Tropical Biomedicine 2019年第12期9卷 501-509页

作者： The Han Nguyen thi Huyen Nguyen Van Minh Nguyen thi Lan Phuong Nguyen thi Van Anh tran Anh Duy Do Sang Moo Kim Faculty of Food Technology Nha Trang University02 Nguyen Dinh Chieu StreetNha Trang CityKhanh HoaVietnam Quality Control Department Institute of Vaccines and Medical BiologicalsNha Trang CityKhanh HoaVietnam Faculty of Pharmacy University of Medicine and Pharmacy of Ho Chi Minh City41 Dinh Tien Hoang StreetHo Chi Minh CityVietnam Research Department of Marine Conservation Research Institute for Marine Fisheries224 Le Lai StreetHai Phong CityVietnam Department of Marine Food Science and Technology Gangneung-Wonju National University7 Jukheon-gilGangneung 25457Republic of Korea

Objective:To investigate antidiabetic and antioxidant activities of the extract and fractions from Vietnamese red seaweed Laurencia ***:The seaweed Laurencia dendroidea was extracted by using microwave-assisted extraction method in 80%*** seaweed extract was then fractionated using different solvents(n-hexane,chloroform,ethyl acetate,butanol and water).These obtained fractions were evaluated forα-glucosidase inhibitory and antioxidant *** activities were tested using DPPH,nitric oxide radical scavenging and metal chelating *** enzyme inhibition mode was determined using Lineweaver-Burk *** acidic and thermal stabilities,the ethyl acetate fraction was treated at pH 2.0 and 100℃,*** residual inhibitory activity of the fraction was calculated based on the initial inhibitory *** in vivo antidiabetic activity,mice were divided into four groups,including normal control,diabetic control,diabetic mice treated with ethyl acetate fraction and diabetic mice treated with *** glucose level of treated mice during acute and prolonged treatments was *** evaluate the toxicity of the ethyl acetate fraction,the body weight changes and activities of liver function enzymes(aspartate transaminase,alanine transaminase and gammaglutamyl transferase)were carried ***:The extract of Laurencia dendroidea showed strongα-glucosidase inhibitory and DPPH radical scavenging *** concentrations affected bothα-glucosidase inhibitory and antioxidant activities.A 80%aqueous methanol was the suitable solvent for extraction of enzyme inhibitors and *** solvent fractions,ethyl acetate fraction had the highest inhibitory activities againstα-glucosidase with a mixed type of inhibition and the strongest antioxidant activities,and was stable under acidic and thermal *** ethyl acetate fraction treated diabetic mice significantly reduced blood glucose level compare

关键词： α-Glucosidase inhibitor Antidiabetic Antioxidant Red seaweeds Vietnam

Hepatocellular carcinoma in patients with renal dysfunction: Pathophysiology, prognosis, and treatment challenges

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World Journal of Gastroenterology 2021年第26期27卷 4104-4142页

作者： Hsuan Yeh Chung-Cheng Chiang Tzung-hai yen Department of Nephrology Chang Gung Memorial Hospital and Chang Gung UniversityTaipei 105Taiwan Department of Gastroenterology and Hepatology Chang Gung Memorial HospitalTaoyuan 333Taiwan

The population of patients with hepatocellular carcinoma(HCC)overlaps to a high degree with those for chronic kidney disease(CKD)and end-stage renal disease(ESRD).The degrees of renal dysfunction vary,from the various stages of CKD to dialysis-dependent ESRD,which often affects the prognosis and treatment choice of patients with *** addition,renal dysfunction makes treatment more difficult and may negatively affect treatment *** study summarized the possible causes of the high comorbidity of HCC and renal *** possible mechanisms of CKD causing HCC involve uremia itself,long-term dialysis status,immunosuppressive agents for postrenal transplant status,and miscellaneous factors such as hormone alterations and *** possible mechanisms of HCC affecting renal function include direct tumor invasion and hepatorenal ***,we categorized the risk factors that could lead to both HCC and CKD into four categories:Environmental toxins,viral hepatitis,metabolic syndrome,and vasoactive *** CKD and ESRD have been reported to negatively affect HCC prognosis,but more research is warranted to confirm ***,ESRD status itself ought not to prevent patients receiving aggressive *** study then adopted the well-known Barcelona Clinic Liver Cancer guidelines as a framework to discuss the indicators for each stage of HCC treatment,treatment-related adverse renal effects,and concerns that are specific to patients with pre-existing renal dysfunction when undergoing aggressive treatments against CKD and *** aggressive treatments include liver resection,simultaneous liver kidney transplantation,radiofrequency ablation,and transarterial ***,focusing on patients unable to receive active treatment,this study compiled information on the latest systemic pharmacological therapies,including targeted and immunotherapeutic *** on available clinical studies and Food and Drug Administration labe

关键词： Hepatocellular carcinoma Chronic kidney disease End-stage renal disease Hemodialysis Cancer prognosis Cancer therapeutics

Quality of Sleep among Pregnant Women

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International Journal of Clinical Medicine 2019年第1期10卷 16-25页

作者： Nguyen thi Thanh Huong Nguyen thi Hoang Thuy Le thi hai yen Faculty of Nursing and Midwifery Hanoi Medical University Hanoi Vietnam Faculty of Nursing Hanoi Medical University Hanoi Vietnam National Hospital of Obstetrics and Gynecology Hanoi Vietnam

Objectives: The study aimed to describe the quality of sleep and explore factors especially Sleep Hygiene Practices associated with sleep quality among pregnant women. Study design: this is a cross-sectional study. Methods: 119 healthy pregnant women in two central hospitals in Vietnam were participated in this study. The Pittsburgh Sleep Quality Index (PSQI) was employed to evaluate sleep quality and the Modified Sleep Hygiene Practices was used to describe sleeping practices among pregnant women. Results: The results showed that while 58.8% pregnant women had quite good sleep quality, 41.2% of pregnant women had mild to moderate quality sleep disturbance. The quality of sleep was better in second trimester, but then getting worst in the third trimester. Multipara experienced worse sleep quality than nullipara. Poor sleep quality had a positive correlation with unhealthy Sleep Hygiene Practices including using an uncomfortable bed (p third trimester as they experience more change in hormone and physiology. Sleep Hygiene Practices should be emphasized in health education for pregnant women.

关键词： Quality of Sleep Pregnant Women

Granulocyte colony-stimulating factor reduces biliary fibrosis and ductular reaction in a mouse model of chronic cholestasis

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Liver Research 2023年第1期7卷 90-98页

作者： Trinh Van Le Thanh Minh Dang Huy Quang Do Ai-Xuan Le Holterman Hong-Thuy Phan-thi Thong Tan tran Nhung hai Truong Laboratory of Stem Cell Research and Application University of Science-VNUHCMHo Chi Minh CityVietnam Vietnam National University Ho Chi Minh CityVietnam Department of Pediatrics and Surgery University of Illinois College of MedicineChicagoILUSA Faculty of Biology and Biotechnology University of Science-VNUHCMHo Chi Minh CityVietnam

Background:Biliary atresia is a rare congenital bile duct disease that is the leading cause of liver fibrosis in *** colony-stimulating factor(GCSF)is a potential therapy for hepatocellular diseases,but data on GCSF for cholestatic conditions remain *** and methods:The current study examines the role of GCSF in improving bile duct obstruction in *** doses were administered:10.0 mg/kg/day and 61.5 mg/kg/day,which is the animal equivalent dose of 5.0 mg/kg in *** days(D7)after bile duct ligation(BDL),Swiss mice were treated with phosphate buffered saline or GCSF for 5 *** intrahepatic adaptive response of BDL mice was evaluated on postsurgical days D12,D19,and ***:Treatment with 61.5 mg/kg of GCSF resulted in a significant increase in circulating leukocytes and neutrophils on *** of liver injury,as shown by reduced aspartate aminotransferase levels,increased albumin levels and survival rate,as well as reduced intrahepatic inflammation and hepatic myeloperoxidase expression,downregulated ductular proliferation,periportal fibroblast activation,and fibrosis,enhanced expressions of hepatocyte growth factor,peroxisome proliferator-activated receptoralpha,and ki67,and suppressed expression of cleaved caspase-3 protein,was noted after treatment with 61.5 mg/kg of ***,GCSF treatment was associated with an increased number of intrahepatic cd3-Sca1tc-Kitt bone marrow cells.

关键词： Bile duct ligation(BDL) Biliary fibrosis Ductular reaction Granulocyte colony-stimulating factor(GCSF) Hepatic stellate cell(HSC)

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越南民众与媒介接触情况调查研究

越南民众与媒介接触情况调查研究

作者： NGUyen thi hai yen 重庆大学

学位级别：硕士

进入二十一世纪以来,随着科学技术的飞速发展,传统媒体以及新媒体的出现给受众的选择越来越多。大众与媒介之间有密切关系,不仅影响媒体发展的趋势,而会影响国家的政治、经济、社会的问题。本文从传播学的视角切入,通过选取越南河内市... 详细信息

进入二十一世纪以来,随着科学技术的飞速发展,传统媒体以及新媒体的出现给受众的选择越来越多。大众与媒介之间有密切关系,不仅影响媒体发展的趋势,而会影响国家的政治、经济、社会的问题。本文从传播学的视角切入,通过选取越南河内市纸桥区的奕望后坊、观花坊与福寿县的福寿小镇、寿禄社为调查对象,采用定量与定性结合的研究方法,结合文献分析、数据统计分析等研究方法。根据越南民众与媒介接触情况、特点以及影响因素,进行探讨民众与报纸、广播、电视、网络等四大媒体接触的类型、内容、习惯等方面的异同点。本文采用SPSS 21.0统计分析软件对283个样本数据分为性别、年龄、职业、婚姻情况、受教育程度的变量进行描述分析和相关性分析。研究发现:(1)电视是越南民众最依赖的媒介渠道,此外,网络、报纸在提供信息方面仍然发挥着重要的作用,相比之下,广播的受众较小;(2)民众对电视传播的内容也是最可靠,其次是报纸,再次是广播,最后是网络;(3)男性人群比女性人群更倾向于媒介接触,年龄越大与媒介接触的需求越少,文职人员、大学生比农民、工人与媒介接触的程度更高,未婚人群与媒介接触多于已婚人群,受教育程度高人群比受教育程度低人群接触媒体更有选择;(4)在越南媒体背景下,民众与媒介接触有所变化。趋势和预测如下:男性人口增多是越南媒体发展的潜力,年轻人更倾向于新媒体,电视、报纸、广播都需要数字化才能生存下去,媒介受众逐渐转为网络媒体以及新媒体,受众与媒介接触的需求越来越高。

关键词：媒介接触越南媒体业大众媒介

Synergetic NO reduction by biomass pyrolysis products simulating their reburning in circulating fluidized bed decoupling combustion

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Chinese Journal of Chemical Engineering 2019年第7期27卷 1680-1689页

作者： hai-Sam Do Tuyet-Suong tran Zhennan Han Xi Zeng Shiqiu Gao Guangwen Xu State Key Laboratory of Multi-phase Complex Systems Institute of Process EngineeringChinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China Institute of Industrial Chemistry and Energy Technology Shenyang University of Chemical TechnologyShenyang 110142China

The present work investigated the synergetic effect of pyrolysis-derived char,tar and gas(py-gas)on NO reduction,which may occur in circulating fluidized-bed decoupling combustion(CFBDC)system treating N-rich *** were carried out in a lab-scale drop-tube reactor for NO reduction by some binary mixtures of reagents including char/py-gas,tar/py-gas and tar/*** a specified total mass rate of0.15 g·min^-1 for NO-reduction reagent,the char/py-gas(binary reagent)enabled the best synergetic NO reduction in comparison with the *** existed effective interactions between char and some species in py-gas(i.e.,H2,CxHy)during NO reduction by pyrolysis products,meanwhile the tar/py-gas or tar/char mixture only caused a positive effect when tar proportion was necessarily lowered to about 26%.On the other hand,the synergetic effects were not improved for all tested binary reagents by increasing the reaction temperature and residence time.

关键词： Biomass Pyrolysis Circulating fluidized bed NO reduction Synergetic effect Decoupling combustion

transfer Learning for Disease Diagnosis from Myocardial Perfusion SPECT Imaging

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Computers, Materials & Continua 2022年第12期73卷 5925-5941页

作者： Phung Nhu hai Nguyen Chi Thanh Nguyen Thanh Trung tran Trung Kien Institute of Information Technology AMSTHanoi11307Vietnam Department of Medical Equipment 108 Military Central HospitalHanoi11610Vietnam

Coronary artery disease(CAD)is one of the most common pathological conditions and the major global cause of *** perfusion imaging(MPI)using single-photon emission computed tomography(SPECT)is a non-invasive method and plays an essential role in diagnosing ***,there is currently a shortage of doctors who can diagnose using SPECT-MPI in developing countries,especially *** on deploying machine learning and deep learning in supporting CAD diagnosis has been noticed for a long ***,these methods require a large dataset and are therefore time-consuming and *** study aims to develop a cost-effective and high-performance CAD classification model to support doctors in these *** this paper,we propose a transfer learning framework for a multi-stage training process with different learning *** process consists of two training stages:a warming up stage in which all layers of a pre-trained model(on ImageNet dataset)are frozen;and a finetuning stage in which a small amount of the top layers are unfrozen and then retrained with a lower learning *** dataset for this study consists of the polar maps from 218 *** popular CNN-based pre-trained models have been investigated,and ResNet152V2-based model has obtained the highest performances with an accuracy of 95.5%,area under the receiver operating characteristic curve(AUC)score 0.932,sensitivity 94.4%,precision 96.4%,and F1-score 95.2%.These performances are competitive or even better than all state-of-the-art approaches in terms of classification accuracy and *** also apply the class activation mapping technique to help explain the model’s predictions and increase the model’s reliability,proving capable of assisting the SPECT image readers in the CAD diagnosis.

关键词： Coronary artery disease deep learning transfer learning SPECTMPI polar maps