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Journal of Materials Science & Technology 2021年第12期71卷 186-194页

作者： Le Thai Duy ji-ye Baek ye-ji mun Hyungtak Seo Department of Materials Science&Engineering Ajou UniversitySuwon16499South Korea Department of Energy Systems Research Ajou UniversitySuwon16499South Korea

Perovskite oxides like S rTiO_(3) at the nanoscale are of interest for eme rging applications,including high-k dielectrics and ***,their synthesis requires long calcination at the elevated temperature,which is a barrier of their application to flexible ***,an effective laser-assisted sol-gel method to patternably produce S rTiO_(3) na noparticles(-100 nm)in selective areas on polyimide substrates(coated with ITO)is ***,the violet-laser power is just 1 W but sufficient to crystallize the material in a short period(a few seconds).Furthermore,developing a flexible device platform using carbon nanotubes(CNT)and SrTiO_(3) nanoparticles for detection of humidity changes at room temperature is *** sensor platform has both capacitive and resistive sensing *** resistive mode with a lower power usage(about 0.2μW)is suitable for long monitoring of humidity in the range of2%RH and *** capacitive mode with higher sensitivity,faster response/recovery time(1-3 min),and lower detection limit(0.5%RH)can be used for calibration *** performance of the flexible sensor is still maintained after 5000 bending cycles at 1.5-cm ***,our synthesis method and the flexible sensor show chances for mass-producing perovskite oxides at low cost for wearable electronics.

关键词： SrTiO_(3) Nanoparticles Laser annealing Patternable Flexible sensor CNT

Effect of cholesterol metabolism on hepatolithiasis

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World Journal of Gastroenterology 2025年第1期31卷 157-162页

作者： Lin Zheng Zi-Yu ye Jun-ji Ma Department of Gastroenterology The Second Hospital of Hebei Medical UniversityHebei Key Laboratory of GastroenterologyHebei Institute of GastroenterologyHebei Clinical Research Center for Digestive DiseasesNo.215 Heping West RoadShijiazhuang 050000Hebei ProvinceChina

Surgical intervention is currently the primary treatment for hepatolithiasis;how-ever,some patients still experience residual stones and high recurrence rates after *** metabolism seems to play an important role in hepatoli-thiasis pathogenesis.A high cholesterol diet is one of the significant reasons for the increasing incidence of ***,regular diet and appropriate medical intervention are crucial measures to prevent hepatolithiasis and reduce recurrence rate after *** dietary cholesterol and drugs that increase cholesterol stone solubility are key therapeutic approaches in treating *** article discusses the cholesterol metabolic pathways related to the pathogenesis of hepatolithiasis,as well as food intake and targeted therapeutic drugs.

关键词： Hepatolithiasis Cholesterol metabolism High-fat diet 3-hydroxy-3-methylglutaryl-coenzyme A reductase Interlobular bile duct

Perfluoropentane-based oxygen-loaded nanodroplets reduce microglial activation through metabolic reprogramming

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Neural Regeneration Research 2025年第4期20卷 1178-1191页

作者： Wanxian Luo Chuanhui Xu Linxi Li Yunxiang ji yezhong Wang Yingjia Li Yongyi ye Department of Medicine Ultrasonics Nanfang HospitalSouthern Medical UniversityGuangzhouGuangdong ProvinceChina Institute of Neuroscience Department of NeurosurgeryThe Second Affiliated Hospital of Guangzhou Medical UniversityGuangzhouGuangdong ProvinceChina

Microglia,the primary immune cells within the brain,have gained recognition as a promising therapeutic target for managing neurodegenerative diseases within the central nervous system,including Parkinson’s *** perfluorocarbon droplets have been reported to not only possess a high oxygen-carrying capacity,but also exhibit remarkable anti-inflammatory ***,the role of perfluoropentane in microglia-mediated central inflammatory reactions remains poorly *** this study,we developed perfluoropentane-based oxygen-loaded nanodroplets(PFP-OLNDs)and found that pretreatment with these droplets suppressed the lipopolysaccharide-induced activation of M1-type microglia in vitro and in vivo,and suppressed microglial activation in a mouse model of Parkinson’s *** suppression led to a reduction in the inflammatory response,oxidative stress,and cell migration capacity in ***,the neurotoxic effects were mitigated,which alleviated neuronal ***,ultrahigh-performance liquid chromatography–tandem mass spectrometry showed that the anti-inflammatory effects of PFP-OLNDs mainly resulted from the modulation of microglial metabolic *** further showed that PFP-OLNDs regulated microglial metabolic reprogramming through the AKT-mTOR-HIF-1α***,our findings suggest that the novel PFP-OLNDs constructed in this study alleviate microglia-mediated central inflammatory reactions through metabolic reprogramming.

关键词： metabolic reprogramming microglia microglial migration nanotherapy neurodegenerative diseases neuroinflammation oxygen-loaded nanodroplets Parkinson’s disease perfluoropentane ultra-performance liquid chromatography–mass spectrometry

Synthesis,Growth Mechanism,and Applications of Zinc Oxide Nanomaterials

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Journal of Materials Science & Technology 2008年第4期24卷 457-472页

作者： Shulin ji Changhui ye Anhui Key Laboratory of Nanomaterials and Technology and Key Laboratory of Materials Physics Institute of SolidState Physics Chinese Academy of Sciences Hefei 230031 China

This article reviews recent progresses in growth mechanism, synthesis, and applications of zinc oxide nano-materials （mainly focusing on one-dimensional （1D） nanomaterials）. In the first part of this article, we briefly introduce the importance, the synthesis methods and growth mechanisms, the properties and applications of ZnO 1D nanomaterials. In the second part of this article, the growth mechanisms of ZnO 1D nanomaterials will be discussed in detail in the framework of vapor-liquid-solid （VLS）, vapor-solid （VS）, and aqueous solution growth （ASG） approaches. Both qualitative and quantitative information will be provided to show how a controlled synthesis of ZnO 1D nanomaterials can be achieved. In the third part of this article, we present recent progresses in our group for the synthesis of ZnO 1D nanomaterials, and the results from other groups will only be mentioned briefly. Especially, experiment designing according to theories will be elaborated to demonstrate the concept of controlled synthesis. In the fourth part of this article, the properties and potential applications of ZnO 1D nanomaterials will be treated. Finally, a summary part will be presented in the fifth section. The future trend of research for ZnO 1D nanomaterials will be pointed out and key issues to be solved will be proposed.

关键词： Zinc Oxide One-dimensional Nanomaterials Controlled synthesis

Multi-user quantum private comparison with scattered preparation and one-way convergent transmission of quantum states

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Science China(Physics,Mechanics & Astronomy) 2017年第9期60卷 7-16页

作者： TianYu ye ZhaoXu ji College of Information & Electronic Engineering Zhejiang Gongshang University

Quantum private comparison(QPC) aims to accomplish the equality comparison of the secrets from different users without disclosing their genuine contents by using the principles of quantum mechanics. In this paper, we summarize eight modes of quantum state preparation and transmission existing in current QPC protocols first. Then, by using the mode of scattered preparation and one-way convergent transmission, we construct a new multi-user quantum private comparison(MQPC) protocol with two-particle maximally entangled states, which can accomplish arbitrary pair's comparison of equality amongK users within one execution. Analysis turns out that its output correctness and its security against both the outside attack and the participant attack are guaranteed. The proposed MQPC protocol can be implemented with current technologies. It can be concluded that the mode of scattered preparation and one-way convergent transmission of quantum states is beneficial to designing the MQPC protocol which can accomplish arbitrary pair's comparison of equality among K users within one execution.

关键词： multi-user quantum private comparison (MQPC) scattered preparation one-way convergent transmission

Report on Childhood Obesity in China (4) Prevalence and Trends of Overweight and Obesity in Chinese Urban School-age Children and Adolescents, 1985-2000

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Biomedical and Environmental Sciences 2007年第1期20卷 1-10页

作者： CHENG-ye ji 无 Institute of Child and Adolescent Health Peking Medical University Health Science Center 38 Xueyuan Road Beijing 100083 China COOPERATIVE STUDY ON CHILDHOOD OBESITY： WORKING GROUP ON OBESITY IN CHINA （WGOC）

Objective To describe the nationwide prevalence of childhood overweight/obesity, and their group variations and trends over the past 20 years in the Chinese urban population. Methods Data sets of boys and girls at the age of 7-18 years collected from the series of Chinese national surveillance on students＇ constitution and health （CNSSCH） between 1985 and 2000 were divided into five socioeconomic and demographic groups, while BMI classification reference proposed by Working Group on Obesity in China （WGOC） was used as screening reference to calculate the prevalence and trends of overweight/obesity in these groups. Results In 2000, the prevalence of obesity and overweight in boys aged 7-18 years was 11.3% and 6.5% in Beijing, 13.2% and 4.9% in Shanghai, 9.9% and 4.5% in coastal big cities, and 5.8% and 2.0% in coastal medium/small-sized cities, respectively, while the prevalence of of obesity and overweight in girls of the same age group was 8.2% and 3.7% in Beijing, 7.3% and 2.6% in Shanghai, 5.9% and 2.8% in coastal big cities, and 4.8% and 1.7% in coastal medium/small-sized cities, respectively. The prevalence of obesity was low in most of the inland cities at an early stage of epidemic overweight. The epidemic manifested a gradient distribution in groups, which was closely related to status （SES） of the study population. However, a dramatic and steady increasing trend was witnessed among all sex-age subgroups in the five urban groups, and such a trend was stronger in boys than in girls, and much stronger in children than in adolescents. Conclusion Although China is at an early stage of epidemic obesity by and large, the prevalence of obesity in her urban population, particularly in coastal big cities has reached the average level of developed countries. The increasing trend has been rapid since early 1990s, and the increments in obesity and overweight are exceptionally high. The prospect of epidemic obesity in China is in no way optimistic. Therefore, preventive

关键词： Obesity Overweight Prevalence Epidemic changes Chinese urban areas School-age children and adolescents

Soft coarse-grained particle model for particle-fluid systems

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Particuology 2024年第1期84卷 178-193页

作者： Yanhao ye ji Xu Wei Ge State Key Laboratory of Multiphase Complex Systems Institute of Process EngineeringChinese Academy of SciencesBeijing100190China School of Chemical Engineering University of Chinese Academy of SciencesBeijing100049China Innovation Academy for Green Manufacture Chinese Academy of SciencesBeijing100190China

By modeling a group of neighboring real particles as a single coarse-grained particle(CGP),discrete particle method(DPM)is now capable of simulating industrial-scale particle-fluid ***,a systematic approach to determine the CGP properties and develop their interaction models is still lacking,which casts uncertainty on the predictivity of the *** this study,collisions between predefined particle groups are analyzed to construct kernel functions for modeling the CGPs and then the model parameters are determined by equating the statistical properties of the CGPs and the real particles in the physical process *** approach is implemented for homogeneous cooling of granular gas,then demonstrated effective in simulating experimental fluidized beds.

关键词： Coarse-grain(CG) Discrete particle method(DPM) Fluidized bed Multi-scale simulation

De Casteljau Algorithm and Degree Elevation of Toric Surface Patches

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Journal of Systems Science & Complexity 2021年第1期34卷 21-46页

作者： LI jinggai ji ye ZHU Chungang School of Mathematical Sciences Dalian University of TechnologyDalian 116024 Key Laboratory for Computational Mathematics and Data Intelligence of Liaoning Province Dalian University of TechnologyDalian 116024China

De Casteljau algorithm and degree elevation of Bézier and NURBS curves/surfaces are two important techniques in computer aided geometric design. This paper presents the de Casteljau algorithm and degree elevation of toric surface patches, which include tensor product and triangular rational Bézier surfaces as special cases. Some representative examples of toric surface patches with common shapes are illustrated to verify these two algorithms. Moreover, the authors also apply the degree elevation of toric surface patches to isogeometric analysis. And two more examples show the effectiveness of proposed method.

关键词： De Casteljau algorithm degree elevation depth elevation isogeometric analysis toric surface patches

Agrobacterium tumefaciens-mediated genetic transformation of the phytopathogenic fungus Penicillium digitatum

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2008年第10期9卷 823-828页

作者： ji-ye WANG Hong-ye LI Institute of Biotechnology Zhejiang University Hangzhou 310029 China

Agrobacterium tumefaciens-mediated transformation (ATMT) system was assessed for conducting insertional mutagenesis in Penicillium digitatum, a major fungal pathogen infecting post-harvest citrus fruits. A transformation efficiency of up to 60 transformants per 106 conidia was achieved by this system. The integration of the hph gene into the fungal genome was verified by polymerase chain reaction (PCR) amplification and sequencing. These transformants tested were also shown to be mitotically stable. Southern blot analysis of 14 randomly selected transformants showed that the hph gene was randomly integrated as single copy into the fungal genome of P. digitatum. Thus, we conclude that ATMT of P. digitatum could be used as an alter-natively practical genetic tool for conducting insertional mutagenesis in P. digitatum to study functional genomics.

关键词： Penicillium digitatum Agrobacterium tumefaciens-mediated transformation (ATMT) Hygromycin B resistance gene lnsertional mutagenesis

Reaction network design and hybrid modeling of S Zorb

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Chinese Journal of Chemical Engineering 2024年第9期73卷 301-310页

作者： Kai ji Zhencheng ye Feng Qian Key Laboratory of Smart Manufacturing in Energy Chemical Process Ministry of EducationEast China University of Science and TechnologyShanghai 200237China Qingyuan Innovation Laboratory Quanzhou 362801China

At present,many countries are becoming more and more stringent in terms of sulfur content in fuel oil.S Zorb is a kind of desulfurization technology with advantages of exceptional desulfurization efficiency and small impact on octane *** meet the needs of environmental requirements and the trend of digitalization in the petrochemical industry,a first-principle model of S Zorb was established based on industry *** order to describe the desulfurization and the other side reactions,a reaction network was designed and the kinetic parameters were estimated by the particle swarm optimization *** hybrid models based on the first-principle model and support vector regression method were established to correct the mass fraction of sulfur and predict the research octane number of the refined gasoline *** results indicate that the hybrid models can predict the mass fraction of PIONA,sulfur content and research octane number of the refined gasoline accurately,of which the mean absolute percentage errors are less than 6%.Hybrid models were then applied to optimize the decision variables to minimize the research octane number *** results show that the average reduction of the loss of research octane number is 21.8%,which suggests that the models developed hold promise for guiding practical production.

关键词： Desulfurization Simulation Reaction kinetics Optimization