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A Reference Vector-Assisted Many-Objective Optimization Algorithm with Adaptive Niche Dominance Relation

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Intelligent Automation & Soft Computing 2024年第2期39卷 189-211页

作者： Fangzhen Ge yating wu Debao Chen Longfeng Shen School of Computer Science and Technology Huaibei Normal UniversityHuaibei340604China School of Physic and Electronic Information Huaibei Normal UniversityHuaibei340604China Anhui Engineering Research Center for Intelligent Computing and Application on Cognitive Behavior(ICACB) Huaibei Normal UniversityHuaibei340604China Anhui Province Key Laboratory of Intelligent Computing and Applications Huaibei Normal UniversityHuaibei340604China Institute of Artificial Intelligence Hefei Comprehensive National Science CenterHefei230000China

It is still a huge challenge for traditional Pareto-dominatedmany-objective optimization algorithms to solve manyobjective optimization problems because these algorithms hardly maintain the balance between convergence and diversity and can only find a group of solutions focused on a small area on the Pareto front,resulting in poor performance of those algorithms.For this reason,we propose a reference vector-assisted algorithmwith an adaptive niche dominance relation,for short MaOEA-AR.The new dominance relation forms a niche based on the angle between candidate solutions.By comparing these solutions,the solutionwith the best convergence is found to be the non-dominated solution to improve the selection pressure.In reproduction,a mutation strategy of k-bit crossover and hybrid mutation is used to generate high-quality offspring.On 23 test problems with up to 15-objective,we compared the proposed algorithm with five state-of-the-art algorithms.The experimental results verified that the proposed algorithm is competitive.

关键词： Many-objective optimization evolutionary algorithm Pareto dominance reference vector adaptive niche

Anterior temporal lobectomy improved mood status and quality of life in Chinese patients with mesial temporal lobe epilepsy:a single-arm cohort study

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Chinese Medical Journal 2023年第4期136卷 407-414页

作者： Song Lu Min Chu Xian Wang yating wu Yue Hou Aihua Liu Department of Neurology Xuanwu Hospital Capital Medical UniversityBeijing 100053China Fuxing Hospital Capital Medical UniversityBeijing 100069China

Background: Many studies have emphasized that selective resection of epileptic lesions in temoral lobe is associated with better preservation of cognition function;whether this applies to patients with refractory mesial temporal lobe epilepsy (MTLE) remains unknown. The objective of this study was to evaluate changes in cognitive functions, mood status, and quality of life after anterior temporal lobectomy in patients with refractory MTLE. Methods: This single-arm cohort study assessed cognitive function, mood status, and quality of life, as well as electroencephalography findings, in patients with refractory MTLE who underwent anterior temporal lobectomy at Xuanwu Hospital from January 2018 to March 2019. Pre- and post-operative characteristics were compared to evaluate the effects of surgery. Results: Anterior temporal lobectomy significantly reduced the frequencies of epileptiform discharges. The overall success rate of surgery was acceptable. Anterior temporal lobectomy did not result in significant changes in overall cognitive functions (P > 0.05), although changes in certain domains, including visuospatial ability, executive ability, and abstract thinking, were detected. Anterior temporal lobectomy resulted in improvements in anxiety and depression symptoms and quality of life. Conclusions: Anterior temporal lobectomy reduced epileptiform discharges and incidence of post-operative seizures as well as resulted in improved mood status and quality of life without causing significant changes in cognitive function.

关键词： Anterior temporal lobectomy Mesial temporal lobe epilepsy Mood status

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硅基集成光开关阵列的高速驱动控制电路设计

浙江大学学报（工学版） 2024年第2期58卷 325-333页

作者：张毅远武雅婷米光灿黄莹储涛浙江大学信息与电子工程学院浙江杭州310027 华为技术有限公司广东东莞523145

通过分析光开关单元的物理结构,提出等效电学模型,用于模拟光开关单元的瞬态响应.基于该模型,针对光开关阵列设计高速驱动控制电路,结合仿真探究电压尖峰对光开关单元瞬态响应的影响.系统测试结果表明,驱动电路施加的电压信号的上升/下... 详细信息

通过分析光开关单元的物理结构,提出等效电学模型,用于模拟光开关单元的瞬态响应.基于该模型,针对光开关阵列设计高速驱动控制电路,结合仿真探究电压尖峰对光开关单元瞬态响应的影响.系统测试结果表明,驱动电路施加的电压信号的上升/下降时间为1.7/1.6 ns,能够满足高速光开关纳秒级切换速度的需求.在该驱动电路的配合下,光开关阵列的切换时间为2.1~5.9 ns,实现了较先进的高速光交换系统.

关键词：光通信光互连硅基光子学硅基光开关驱动控制电路

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“法律的其他规定”所生之债解释论

河南财经政法大学学报 2024年第2期39卷 71-81页

作者：柳经纬吴雅婷闽江学院法学院福建福州350000

《民法典》第一百一十八条第二款规定的“法律的其他规定”所生之债,是指因合同、侵权行为、无因管理和不当得利以外的民事法律事实而发生的债,它不是一种债的具体类型,而是形态各异的债的统称。“法律的其他规定”所生之债分布在民法... 详细信息

《民法典》第一百一十八条第二款规定的“法律的其他规定”所生之债,是指因合同、侵权行为、无因管理和不当得利以外的民事法律事实而发生的债,它不是一种债的具体类型,而是形态各异的债的统称。“法律的其他规定”所生之债分布在民法典、民商事特别法以及公法等广阔的法律领域,既有法定之债,也有意定之债,它们与合同之债、侵权行为之债、无因管理之债和不当得利之债共同构成债的体系,体现了债的体系的开放性。

关键词：《民法典》第一百一十八条债债的发生债的体系

Metal–ligand interfaces for well-defined gold nanoclusters

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Science China Chemistry 2023年

作者： Dan Yang yating wu Zhaotong Yuan Chunmei Zhou Yihu Dai Xiaoyue Wan Yan Zhu Yanhui Yang Institute of Advanced Synthesis School of Chemistry and Molecular Engineering Nanjing Tech University School of Chemistry and Chemical Engineering Nanjing University College of Material and Chemical Engineering Minjiang University

Ligand engineering for well-defined gold nanoclusters (Au NCs) is getting more extensive attention.Organizing the Au–ligand interfaces on gold NCs can achieve the structural and functional control.This review focuses on the Au–ligand interfaces including gold–phosphorus (Au–P),gold–sulfur (Au–S),gold–selenium (Au–Se),gold–carbon (Au–C),and gold–nitrogen (Au–N),derived from the bonding between Au atoms and the different ligands (e.g.,organic phosphine,thiolate,selenolate,alkynyl,n-heterocyclic carbene and nitrogenous ligands).The formation mechanism of Au–ligand interfaces is well discussed.In addition,the effects of Au–ligand interfaces on the stability,optical property,and catalysis are also presented.We hope the advances in this research area can boost the development of Au NC sciences.

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Atomically Precise Water-Soluble Gold Nanoclusters:Synthesis and Biomedical Application

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Precision Chemistry

Precision Chemistry 2023年第8期1卷 468-479页

作者： Qian Yan Zhaotong Yuan yating wu Chunmei Zhou Yihu Dai Xiaoyue Wan Dan Yang Xu Liu Nianhua Xue Yan Zhu Yanhui Yang Institute of Advanced Synthesis School of Chemistry and Molecular EngineeringNanjing Tech UniversityNanjing 211816China School of Chemistry and Chemical Engineering Nanjing UniversityNanjing 210093China College of Material and Chemical Engineering Minjiang UniversityFuzhou 350108China

Atomically precise water-soluble gold nanoclusters(Au NCs)protected by organic ligands have attracted growing attention in serving as unique nanomaterials with the potential to generate theranostic tools(bioimaging,biosensing,and biotherapy),due to their ultrasmall size,superior photoluminescence,good biocompatibility,and nontoxicity.More importantly,Au NCs afford a well-defined atomic packing structure and molecular purity,providing a superior platform to unravel the structure−performance correlations for biodistribution,biological pharmacokinetics,and excretion of Au NCs.In this Review,we mainly survey the synthesis of water-soluble Au NCs and the recent progress in biomedicine of Au NCs,including bioimaging,biosensing,and biotherapy.The effects of ligand and size on the biomedical properties are discussed in detail.We hope that the advances in this research area can expand the applications of Au NCs in biomedicine.

关键词： Gold nanocluster well-defined structure water-soluble biodiagnostic theranostic

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鰤鱼诺卡氏菌疫苗对石斑鱼免疫效果研究

中国农业科技导报 2024年第2期26卷 145-152页

作者：高浩峰邵蓬武尊吴雅婷汪笑宇天津农学院水产学院天津市水产生态及养殖重点实验室天津300392 天津市水产研究所天津300392

为探究鰤鱼诺卡氏菌灭活疫苗对石斑鱼的免疫效果,通过免疫基因表达量分析疫苗对石斑鱼的免疫保护。利用鰤鱼诺卡氏菌制备福尔马林灭活全菌疫苗,通过腹腔注射法对珍珠龙胆石斑鱼进行免疫,利用荧光定量法检测免疫后该鱼的肾脏、肝脏和脾3... 详细信息

为探究鰤鱼诺卡氏菌灭活疫苗对石斑鱼的免疫效果,通过免疫基因表达量分析疫苗对石斑鱼的免疫保护。利用鰤鱼诺卡氏菌制备福尔马林灭活全菌疫苗,通过腹腔注射法对珍珠龙胆石斑鱼进行免疫,利用荧光定量法检测免疫后该鱼的肾脏、肝脏和脾3个器官中TLR2、MyD88、TNF-α、IL-1β免疫基因表达量的变化。结果显示,注射灭活疫苗后,TNF-α、IL-1β基因表达量在肾脏组织中较高,MyD88基因表达量在脾组织中较高,TLR2基因表达量在肝脏组织中较高;除脾组织中的TNF-α基因相对表达量出现下降趋势外,其余基因的表达量在所有器官中都呈现出上调的趋势。研究结果为探索珍珠龙胆石斑鱼与诺卡氏菌的相互作用提供理论基础,为渔业疫苗开发和应用奠定基础。

关键词：鰤鱼诺卡氏菌石斑鱼灭活疫苗 TLR2 MyD88 TNF-α IL-1β

基于Q-Learning的分簇无线传感网信任管理机制

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上海大学学报（自然科学版） 2024年第2期30卷 255-266页

作者：赵远亮王涛李平吴雅婷孙彦赞王瑞上海大学通信与信息工程学院上海200444

针对无线传感器网络中存在的安全问题,提出了基于Q-Learning的分簇无线传感网信任管理机制(Q-learning based trust management mechanism for clustered wireless sensor networks,QLTMM-CWSN).该机制主要考虑通信信任、数据信任和能量信任3个方面.在网络运行过程中,基于节点的通信行为、数据分布和能量消耗,使用Q-Learning算法更新节点信任值,并选择簇内信任值最高的节点作为可信簇头节点.当簇中主簇头节点的信任值低于阈值时,可信簇头节点代替主簇头节点管理簇内成员节点,维护正常的数据传输.研究结果表明,QLTMM-CWSN机制能有效抵御通信攻击、伪造本地数据攻击、能量攻击和混合攻击.

关键词：无线传感器网络 Q-Learning 信任管理机制网络安全

超声弹性对比指数联合C-TIRADS鉴别诊断甲状腺4类结节良恶性的价值

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中国超声医学杂志 2024年第1期40卷 4-7页

作者：卢建明陈建东田锦孙艳娟武雅婷宁夏医科大学总医院超声科

目的探讨超声弹性对比指数(ECI)联合中国甲状腺影像报告与数据系统(C-TIRADS)鉴别诊断甲状腺结节超声恶性危险分层指南中4类结节的价值。方法收集超声科检查并获得病理诊断的共216个C-TIRADS 4类甲状腺结节。结果 216个C-TIRADS 4类... 详细信息

目的探讨超声弹性对比指数(ECI)联合中国甲状腺影像报告与数据系统(C-TIRADS)鉴别诊断甲状腺结节超声恶性危险分层指南中4类结节的价值。方法收集超声科检查并获得病理诊断的共216个C-TIRADS 4类甲状腺结节。结果 216个C-TIRADS 4类甲状腺结节中，病理证实为恶性结节129个、良性结节87个。C-TIRADS定义为4a类结节、病理证实为良性的结节个数明显高于恶性；C-TIRADS定义为4b、4c类结节，病理诊断为恶性的数量明显高于良性(P<0.05)。ECI鉴别甲状腺结节良恶性的最佳临界值为2.635,恶性结节ECI均值为2.83±0.42,良性结节ECI均值为2.03±0.52,恶性结节ECI均值明显高于良性结节ECI均值，良、恶性结节ECI均值比较差异有统计学意义(t=6.659,P<0.001)。以病理诊断结果为金标准，C-TIRADS分类标准诊断甲状腺4类结节良恶性的灵敏度、特异度、准确度分别为75.2%、65.5%、71.3%;ECI诊断甲状腺4类结节良恶性的灵敏度、特异度、准确度分别为79.4%、84.0%、80.1%;两者联合诊断良恶性的灵敏度、特异度、准确度分别为87.3%、96.0%、89.9%;C-TIRADS联合ECI较独立应用C-TIRADS、ECI鉴别诊断甲状腺4类结节良恶性的灵敏度、特异度及准确度更好。结论 C-TIRADS联合ECI较独立应用C-TIRADS、ECI鉴别诊断甲状腺结节超声恶性危险分层指南中4类结节良恶性的灵敏度、特异度及准确度更好，可有效降低细针穿刺细胞学检查(FNAC)率，有利于临床更好地制定诊治策略。

关键词：超声弹性对比指数甲状腺结节鉴别诊断