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Percutaneous decannulation of extracorporeal membrane oxygenation using mANTA device:A real-world single-center experience

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World Journal of Cardiology 2024年第10期16卷 574-579页

作者： Ioannis milioglou Alice Qian Pedro Rafael Vieira de Oliveira Salerno Gabriel Tensol Rodrigues Pereira Luis Augusto Palma Dallan Kelsey E Gray michael morrison yasir Abu-Omar mohammad Eldiasty Cristian Baeza Department of Cardiology University Hospitals Cleveland Medical CenterClevelandOH 44106United States Department of Surgery University Hospitals Cleveland Medical Center and Case Western Reserve University School of MedicineClevelandOH 44106United States

BACKGROUND The mANTA vascular closure device(VCD)represents a novel approach to achieving hemostasis after large-bore femoral access *** clinical studies have evaluated the efficacy of the mANTA device across a range of patient populations undergoing different ***,there is still a paucity of data available concerning the use of mANTA devices in aiding the decannulation of venoarterial extracorporeal membrane oxygenation(VAECmO).AIm To present our single-center experience of utilizing the mANTA VCD in patients undergoing this *** This single-center study included all patients undergoing percutaneous decannulation of femoral VA-ECmO using the mANTA plug-based VCD between January 2021 and October 2023 at University Hospitals Cleveland medical *** criteria were adult patients who required prolonged(>24 hours)hemodynamic support with *** included all-cause mortality,hemostasis,bleeding,limb ischemia,and site *** This is a retrospective cohort study of 19 patients with a mean age of 56.8 *** of them were males with a mean body mass index of *** most common extracorporeal membrane oxygenation indication was acute coronary syndrome complicated by cardiogenic shock at 36.8%.The mean length of intensive care unit stay for these patients was 18.8±8.42 *** out of 19 patients survived to *** mANTA device was successfully deployed in 19 patients,with 10 procedures conducted at the bedside and 9 in an operating room *** hemostasis was achieved within 5 minutes of mANTA deployment in 17 out of 19 *** 2 patients manual compression after manta deployment was required to achieve adequate ***,acute lower extremity ischemia was noted in two patients,necessitating endovascular *** infections were reported at the site of mANTA *** Overall,based on our experience and that of other centers,the mANTA VCD

关键词： Extracorporeal membrane oxygenation mANTA Decannulation Hemostasis Ischemia

Partial Fusion (F) Gene Analysis of Newcastle Disease Virus Detected in Pakistan during 2021-2022

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Journal of Biosciences and medicines 2024年第5期12卷 256-275页

作者： muhammad Danish mehmood Huma Anwar Ul-Haq Rauf Khalid yasir Amin muhammad Usman Ghani muhammad Ismail Rabia Habib Fareeha Arshed Abdul Rasheed Shaukat Institute of molecular Biology & Biotechnology University of Lahore Lahore Pakistan Research & Development Division Ottoman Pharma Lahore Pakistan Quality Assurance Department Ottoman Pharma Lahore Pakistan Veterinary Research and Disease Investigation Center Abbottabad Pakistan Quality Control Department Ottoman Pharma Immuno Lahore Pakistan Production Department Ottoman Pharma Lahore Pakistan Poultry Production Department Sabir&#8217s Poultry Pvt. Ltd. Sabroso Pakistan

Newcastle disease (ND) virus is a leading threat to commercial and domestic poultry in Pakistan. The virus infects and constitutes irreversible impairment to the nervous system, damages the respiratory system, and marks severe gastrointestinal lesions leading to heavy mortality in short-living birds and substantial losses in layers and breeders. The continuous emergence and evolution of the virus made it inclined to evade the humoral response and indirectly the circumvention of artificial active immunization. Newcastle disease is caused by the orthoavula genus of the paramyxoviridae family and has shown high genetic diversity even in their genotypes while information regarding enzootic trends of the virus is scanty in Pakistan. A total of 40 tracheal samples of NDV were collected from different commercial broiler farms and 11 isolates of NDV were identified. In the current study, we determined the genetic diversity of the Newcastle disease virus based on the partial sequencing of the fusion protein gene available in the NCBI database. Genetic analysis showed that seven isolates belonged to class I genotype VII and four belonged to class II genotype II. Interestingly, two isolates had epidemiological connections with vaccine-like class II genotype II. Our findings, concerning the recent outbreaks of class I genotype VII and class II genotype II of NDV in vaccinated commercial flocks, suggest possible potential partial mutations in the fusion protein gene. Genetic diversity and formation of the new cleavage site in an important neutralizing protein of wild strain are linked with the potency of artificial active immunization and a major cause of vaccine failure.

关键词： Newcastle Disease Virus Haemagglutination Inhibition Polymerase Chain Reaction Phylogenetic Tree mutation Analysis

Temperature Uniformity,Correlations and the Flow Field in Swirling Impinging Jets

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Journal of Thermal Science 2023年第2期32卷 662-679页

作者： Zahir U.AHmED yasir m.AL-ABDELI Department of mechanical Engineering Khulna University of Engineering&TechnologyKhulna 9203Bangladesh School of Engineering Edith Cowan UniversityJoondalupWA 6027Australia

Infrared thermography,velocity and impingement pressure measurements alongside numerical modelling are used in this study to resolve(heated)surface temperature distributions of turbulent swirling impinging jets for two Reynolds numbers(Re=11600 and 24600).Whilst building upon earlier discoveries for this same geometry,this paper provides three new contributions:(1)identifying the role of impingement distance(H/D)as a deciding factor in the trade-off between more efficient heat transfer(at high swirl numbers)and achieving better substrate temperature uniformity(lower gradients),(2)developing correlations to predict Nusselt number for swirling and non-swirling cooling jets,and(3)predicting the underlying mixing field in these jets and its interplay with the thermal distributions *** indicate substrate temperature uniformity varies based on H/D and swirl intensity(S)with a significant level of thermal non-uniformity occurring in near-field impingement(H/D=1)at stronger swirl(S=0.59 and 0.74).Four correlations describing the effects of S,Re,and H on the average heat transfer and stagnation heat transfer are developed and yield accuracies of 8%and 12%,*** recirculation near the impingement surface is predicted at H/D=1 for stronger swirl jets which disappears at other substrate *** peak wall shear stress reduces and the flow impingement becomes radially wider at higher H/D and *** turbulence or eddy viscosity regions for non-swirling jets(S=0)are predicted in the shear layer and entrainment regions at H/D=1,but such turbulence is confined to the impingement and wall jet regions for strongly swirling flows.

关键词： Temperature uniformity Nusselt number IR imaging CTA RANS

Fuzzy Logic Control of a Head-movement Based Semi-autonomous Human–machine Interface

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Journal of Bionic Engineering 2023年第2期20卷 645-655页

作者： yasirÖzlük Eda Akman Aydin Institute of Sciences Selçuk UniversityAlaaddin Keykubad CampusSelçukluKonya42130Turkey Faculty of Technology Electrical and Electronics EngineeringGazi University06500 Teknikokullar BesevlerAnkara06500Turkey

Quadriplegia is a neuromuscular disease that may cause varying degrees of functional loss in trunk and *** such cases,head movements can be used as an alternative communication *** this study,a human–machine interface which is controlled by human head movements is designed and *** proposed system enables users to steer the desired movement direction and to control the speed of an output device by using head *** movements of the users are detected using a 6 DOF ImUs measuring three-axis accelerometer and three-axis *** head movement axes and the Euler angles have been associated with movement direction and speed,*** ensure driving safety,the speed of the system is determined by considering the speed requested by the user and the obstacle distance on the *** this context,fuzzy logic algorithm is employed for closed-loop speed control according to distance sensors and reference speed data.A car model was used as the output device on the machine ***,the wireless communication between human and machine interfaces provides to adapt this system to any remote device or *** implemented system was tested by five *** of the system was evaluated in terms of task completion times and feedback from the subjects about their experience with the *** indicate that the proposed system is easy to use;and the control capability and usage speed increase with user *** control speed is improved with the increase in user experience.

关键词： Human-machine interface(HmI) Head-movement Obstacle avoidance Inertial measurement unit(ImU) Fuzzy logic

Progress on global hepatitis elimination targets

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World Journal of Gastroenterology 2021年第47期27卷 8199-8200页

作者： yasir Waheed multidisciplinary Laboratory Foundation University Medical CollegeFoundation University IslamabadIslamabad 44000Pakistan

In 2016,the World Health Assembly adopted a Global Health Sector Strategy on viral hepatitis,with targets set for the years 2020 and 2030 to achieve hepatitis *** main target of hepatitis elimination strategy is to reduce the incidence of hepatitis B virus(HBV)and hepatitis C virus(HCV)by 90%and mortality by 65%in *** last 5 years,the number of people receiving HCV treatment has increased from 1 million to 9.4 million;however,this number is far from the 2030 target of 40 million people receiving HCV *** and HCV incidence rates are down from 1.4 million to 1.1 million annual deaths but this is far from the 2030 target ofmillion *** coronavirus disease 2019 pandemic has severely affected the efforts in the fight against *** major donor has committed to investing in the fight against *** is running *** is a need to speed up efforts in the fight against hepatitis to achieve hepatitis elimination by 2030.

关键词： Hepatitis elimination Blood donations Safe injections Hepatitis B vaccination Harm reduction

Effect of Stitching on Plain and Open-hole Strength of CFRP Laminates

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Chinese Journal of Aeronautics 2012年第3期25卷 473-484页

作者： ZHENG Yun CHENG Xiaoquan yasir Baig School of Economics and management Beihang University Beiiing l OO191. China School of Aeronautical Science and Engineering Beihang University Beijing 100191 China

Experimental and analytical investigation is conducted to explore the effects of stitching on plain （without hole） and open-hole compressive and tensile strength of uniweave T300/QY9512 laminates under different environmental conditions （20 ℃/dry and wet, 150 ℃/dry and wet）. Strength performance of stitched composite laminates is also studied using finite element analysis （FEA） model and compared with the experimental results to validate the model. It is found that under similar environmental conditions, the open-hole compressive strength of stitched laminate is decreased and open-hole tensile strength increased as compared to the unstitched laminates. Predicted tensile and compressive strengths are found to be in a good agreement with the test results and the relative error in all cases is less than 15%.

关键词： composite materials stitching finite element method resin film infusion hygrothermal

Effect of interferon plus ribavirin therapy on hepatitis C virus genotype 3 patients from Pakistan:Treatment response,side effects and future prospective

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Asian Pacific Journal of Tropical medicine 2015年第2期8卷 85-89页

作者： yasir Waheed Atta ur Rahman School of Applied Biosciences National University of Sciences & Technology(NUST)Islamabad 44000Pakistan

more than 10 million people are suffering from hepatitis C virus(HCV) in Pakistan,The available treatment option is a combination of interferon and *** response is linked with several factors and also induces a number of side *** searched in *** medi Net and Coogle Scholar for the articles presenting the effect of interferon plus ribavirin therapy on HCV patients from Pakistan,their side effects and future *** major prevalent HCV genotype in Pakistan is *** interferon alpha plus ribavirin showed sustained virological response of 54%-64%while pegylaled interferon alpha plus ribavirin showed sustained virological response of 58%-75%.IL-28 B CC genotype is linked with better sustained virological *** on patients with HCV genotype 3 infections showed no correlation between treatment response and interferon sensitivity determining region *** therapy is linked with a number of side effects like thyroid *** disorders,weight loss,gastrointestinal tract side effects and neuropsychiatric side *** side effects of clubbing of fingers and seizures were also observed in a couple of *** alpha plus ribavirin therapy showed better response rate in HCV genotype 3 patients from Pakistan with number of side effects.A couple of interferon free therapies are light of hope for the patients living with HCV.

关键词： Hepatitis C virus Interferon therapy Genotype 3

Optimal‑Control‑Based Eco‑Driving Solution for Connected Battery Electric Vehicle on a Signalized Route

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Automotive Innovation 2023年第4期6卷 586-596页

作者： Hafiz muhammad yasir Naeem yasir Awais Butt Qadeer Ahmed Aamer Iqbal Bhatti Control and Signal Processing Research Group(CASPR) Department of Electrical EngineeringCapital University of Science and Technology(CUST)Islamabad ExpresswayKahuta RoadZone‑V IslamabadIslamabadPakistan Department of Electrical Engineering National University of Technology(NUTECH)IslamabadPakistan Center for Automotive Research Ohio State UniversityColumbusOHUSA

Speed advisory systems have been used for connected vehicles to optimize energy ***,for their practical utilization,presence of preceding vehicles and signals must be taken into ***,for Battery Electric Vehicles(BEVs),factors that deteriorate battery’s life cycle and discharging time must also be *** paper proposes an eco-driving control for connected BEV with traffic signals and other safety *** signals are considered as interior point constraints,while inter-vehicle distance with preceding vehicles,vehicle speed and battery charging/discharging limits,are considered as state safety ***-forward simulator based Speed Guidance model is applied to follow the optimized velocity under powertrain safety *** of the proposed methodology is tested on a 5.3-km route in Islamabad,*** traffic data using Simulation of Urban mobility under different driving scenarios is *** the proposed method,around 21% energy can be saved compared to the preceding vehicles that followed their random velocities under the same traffic and route *** means the EV controlled by the proposed method can have longer driving ***,the host BEV has crossed signals during their green time without collision with preceding *** charging rates and terminal Depth of Discharge indicate less number of charging cycles,thus proving the usefulness of the proposed solution as battery’s lifesaving strategy.

关键词： Eco-driving First-order Thevenin model Inter-vehicle safety constraint Interior point constraints

Faster metallic Surface Defect Detection Using Deep Learning with Channel Shuffling

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Computers, materials & Continua 2023年第4期75卷 1847-1861页

作者： Siddiqui muhammad yasir Hyunsik Ahn Department of Robot System Engineering Tongmyong UniversityBusan48520Korea School of Artificial Intelligence Tongmyong UniversityBusan48520Korea

Deep learning has been constantly improving in recent years,and a significant number of researchers have devoted themselves to the research of defect detection *** and recognition of small and complex targets is still a problem that needs to be *** authors of this research would like to present an improved defect detection model for detecting small and complex defect targets in steel *** steel strip production,mechanical forces and environmental factors cause surface defects of the steel ***,the detection of such defects is key to the production of high-quality ***,surface defects of the steel strip cause great economic losses to the high-tech *** far,few studies have explored methods of identifying the defects,and most of the currently available algorithms are not sufficiently ***,this study presents an improved real-time metallic surface defect detection model based on You Only Look Once(YOLOv5)specially designed for small *** the smaller features of the target,the conventional part is replaced with a depthwise convolution and channel shuffle *** assigning weights to Feature Pyramid Networks(FPN)output features and fusing them,increases feature propagation and the network’s characterization *** experimental results reveal that the improved proposed model outperforms other comparable models in terms of accuracy and detection *** precision of the proposed model achieved by mAP@0.5 is 77.5%on the Northeastern University,Dataset(NEU-DET)and 70.18%on the GC10-DET datasets.

关键词： Defect detection deep learning convolution neural network object detection YOLOv5 shuffleNetv2