Effect of interferon plus ribavirin therapy on hepatitis C virus genotype 3 patients from Pakistan:Treatment response,side effects and future prospective

作     者：Yasir Waheed 

作者机构：Atta ur Rahman School of Applied BiosciencesNational University of Sciences & Technology(NUST)Islamabad 44000Pakistan 

出 版 物：《Asian Pacific Journal of Tropical Medicine》 (亚太热带医药杂志（英文版）)

年 卷 期：2015年第8卷第2期

页      面：85-89页

核心收录：

学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1002[医学-临床医学] 100401[医学-流行病与卫生统计学] 10[医学] 

主　　题：Hepatitis C virus Interferon therapy Genotype 3 

摘      要：More than 10 million people are suffering from hepatitis C virus(HCV) in Pakistan,The available treatment option is a combination of interferon and *** response is linked with several factors and also induces a number of side *** searched in *** Medi Net and Coogle Scholar for the articles presenting the effect of interferon plus ribavirin therapy on HCV patients from Pakistan,their side effects and future *** major prevalent HCV genotype in Pakistan is *** interferon alpha plus ribavirin showed sustained virological response of 54%-64%while pegylaled interferon alpha plus ribavirin showed sustained virological response of 58%-75%.IL-28 B CC genotype is linked with better sustained virological *** on patients with HCV genotype 3 infections showed no correlation between treatment response and interferon sensitivity determining region *** therapy is linked with a number of side effects like thyroid *** disorders,weight loss,gastrointestinal tract side effects and neuropsychiatric side *** side effects of clubbing of fingers and seizures were also observed in a couple of *** alpha plus ribavirin therapy showed better response rate in HCV genotype 3 patients from Pakistan with number of side effects.A couple of interferon free therapies are light of hope for the patients living with HCV.