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世界核心医学期刊文摘（神经病学分册） 2005年第3期1卷 3-3页

作者： yardley l Donovan-Hall M. Smith H.E. 黄卫东 School of Psychology University of Southampton Highfield So uthampton SO17 1BK United Kingdom Dr.

Background: Dizziness is a very common symptom and is usually managed in prima ry care. Vestibular rehabilitation for dizziness is a simple treatment that may be suitable for primary care delivery, but its effectiveness has not yet been de termined. Objective: To evaluate the effectiveness of nurse delivered vestibula r rehabilitation in primary care for patients with chronic dizziness. Design: Si ngle blind randomized, controlled trial. Setting: 20 general practices in south ern England. Patients: 170 adult patients with chronic dizziness who were random ly assigned to vestibular rehabilitation (n = 83) or usual medical care (n = 87) . Intervention: Each patient received one 30 to 40 minute appointment with a p rimary care nurse. The nurse taught the patient exercises to be carried out dail y at home, with the support of a treatment booklet. Measurements: Primary outcom e measures were baseline, 3 month, and 6 month assessment of self reported sp ontaneous and provoked symptoms of dizziness, dizzi ness related quality of li fe, and objective measurement of postural stability with eyes open and eyes clos ed. Results:At 3 months, improvement on all primary outcome measures in the vest ibular rehabilitation group was significantly greater than in the usual medical care group; this improvement was maintained at 6 months. Of 83 treated patients, 56 (67%) reported clinically significant improvement compared with 33 of 87 (3 8%) usual care patients (relative risk, 1.78 [95%CI, 1.31 to 2.42]). limitat io ns: Psychological elements of the therapy may have contributed to outcomes, and the treatment may be effective only for well motivated patients. Conclusions: V estibular rehabilitation delivered by nurses in general practice improves sympto ms, postural stability, and dizziness related handicap in patients with chronic dizziness.

关键词：前庭功能功能康复训练医学护理患者治疗效果眩晕患者单盲综合医院生活质量诱发性临床症状

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在血压控制不良的高血压患者中使用数字化干预的家庭和在线血压管理:随机对照试验

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中华高血压杂志 2021年第5期29卷 427-427页

作者： McMa-nus RJ little P Stuart B Morton K Raftery J Kelly J Bradbury K Zhang J Zhu S Murray E May CR Mair FS Michie S Smith P Band R Ogburn E AllenJ Rice C Nut-tall J Williams B yardley l 陈嘉睿(译) 叶鹏(审校) 不详

HOME BP试验(The home and online management and evaluation of blood pressure)的目的是评估在初级预防中结合自我监测和自我管理的数字化干预在高血压管理中的作用。研究者纳入英国76个治疗中心经过治疗但血压控制不好(>140/90 mm H... 详细信息

HOME BP试验(The home and online management and evaluation of blood pressure)的目的是评估在初级预防中结合自我监测和自我管理的数字化干预在高血压管理中的作用。研究者纳入英国76个治疗中心经过治疗但血压控制不好(>140/90 mm Hg, 1 mm Hg=0.133 kPa)并能上网的患者622例,进行自动确定主要终点的公开随机对照试验。

关键词：初级预防血压管理随机对照试验自我监测血压控制高血压患者自我管理

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Clinical features and determinants of VO_(2peak) in de novo heart transplant recipients

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World Journal of Transplantation 2018年第5期8卷 188-197页

作者： Katrine Rolid Arne K Andreassen Marianne yardley Elisabeth Bj?rkelund Kristjan Karason Julia P Wigh Christian H Dall Finn Gustafsson lars Gullestad Kari Nytr?en Department of Cardiology Oslo University Hospital the Norwegian Health Association Faculty of Medicine University of Oslo KG Jebsen Center for Cardiac Research and Center for Heart Failure Research University of Oslo Department of Cardiology Sahlgrenska University Hospital Department of Physical Therapy Sahlgrenska University Hospital Department of Cardiology Bispebjerg University Hospital Department of Cardiology Rigshospitalet University Hospital

AIM To study exercise capacity and determinants of early peak oxygen consumption(VO_(2peak)) in a cohort of de novo heart transplant(HTx) recipients. METHODS To determine possible central(chronotropic responses, cardiopulmonary and hemodynamic function) and peripheral factors(muscular exercise capacity and body composition) predictive of VO_(2peak), a number of different measurements and tests were performed, as follows: Cardiopulmonary exercise testing(CPET) was performed mean 11 wk after surgery in 81 HTx recipients > 18 years and was measured with breath by breath gas exchange on a treadmill or bicycle ergometer. Metabolic/respiratory measures include VO_(2peak) and VE/VCO2 slope. Additional measures included muscle strength testing, bioelectrical impedance analysis, echocardiography, blood sampling and health-related quality of life. Based on the VO_(2peak)(ml/kg per minute) median value, the study population was divided into two groups defined as a low-capacity group and a high-capacity group. Potential predictors were analyzed using multiple regression analysis with VO_(2peak)(l/min) as the dependent *** The mean ± standard deviation(SD) age of the total study population was 49 ± 13 years, and 73% were men. This de novo HTx cohort demonstrated a median VO_(2peak) level of 19.4 ml/kg per min at 11 ± 1.8 wk postHTx. As compared with the high-capacity group, the low-capacity group exercised for a shorter time, had lower maximal ventilation, O_2 pulse, peak heart rate and heart rate reserve, while the VE/VCO_2 slope was higher. The low-capacity group had less muscle strength and muscular exercise capacity in comparison with the highcapacity group. In order of importance, O_2 pulse, heart rate reserve, muscular exercise capacity, body mass index, gender and age accounted for 84% of the variance in VO_(2peak)(l/min). There were no minor or major serious adverse events during the CPET. CONClUSION Although there is great individual variance among de novo

关键词： Cardiopulmonary exercise testing Early VO2peak De novo heart transplant Health related quality of life Muscle strength

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