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Diagnosis of Wastewater Contamination by Metalic Trace Elements (MTE) in the Areas of Yopougon (South Abidjan) and Marcory, Koumassi (North Abidjan) from March to July 2021

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Journal of Materials Science and Chemical Engineering 2023年第10期11卷 19-28页

作者： Lydie Nina Amon Aboubakar Sidik Diaby Alfred Niamien kouamé kouamé Eric yao Ali Sanou Léon Koffi Konan Kalpy Julien Coulibaly Mireille Dosso Institut Pasteur of Cô te d’Ivoire Environment and Health Department Abidjan C&#244te d’Ivoire Ivorian Anti-Pollution Center Abidjan C&#244te d’Ivoire Laboratory of Composition and Reaction of Matter Félix Houphou&#235t-Boigny University Abidjan C&#244te d’Ivoire Laboratory of Hydrobiology Felix Houphouet Boigny University Abidjan C&#244te d’Ivoire Institut National Polytechnique of Félix Houphouë t-Boigny (INP-HB) Laboratory of Industrial Synthesis Processes Environment and New Energies (LAPISEN) Yamoussoukro C&#244te d’Ivoire

Contamination of the aquatic environment by Metallic Trace Elements (MTE) is a major problem encountered in our environment today. In Côte d’Ivoire, in some municipals, residential and industrial areas in the city of Abidjan, waste water of worrying quantity is discharged into the rainwater drainage channels which flow directly into the Ebrié lagoon. In order to identify the origin of the pollution by metallic trace elements (MTE) transported by this water, samples of wastewater were collected and then analyzed. ICP-MS was used for MTE (Cu, Fe, Zn, Al, Pb, Cd) analyses and results were statistically processed in multivariate form using PCA and Excel. The results showed high concentrations of metals, with the exception of Cd. The typological structure represents 85.74% of the total information for the MTE. Plan F1 represents 63.90% of the variance and describes water pollution by copper (0.95), zinc (0.90), iron (0.84) and aluminum (0.84). Plan F2 represents 21.84% and describes the enrichment of water with lead (0.84). It seems more than necessary to make manufacturers aware of the need to install wastewater treatment systems in order to avoid their discharge into the environment.

关键词： MTE Wastewater Typology

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Prevalence and Factors Associated with Intestinal Metaplasia in Chronic Helicobacter pylori Gastritis in a Country with High Endemicity: Ivory Coast Case

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Open Journal of Gastroenterology 2023年第12期13卷 401-410页

作者： Hatrydt Guillaume Dimitri kouamé Lisiane Mewetieh Kouassi Olivier Claver Koffi Bathaix Fulgence Mamert yao Medical Sciences Training and Research Unit of Abidjan Félix Houphou&#235t-Boigny University Abidjan Ivory Coast Hepatology and Gastroenterology Unit Yopougon University Hospital Abidjan Ivory Coast

Context/Objective: Few studies have been carried out in a country with high endemicity for Helicobacter pylori (H. pylori) infection in Sub-Saharan Africa looking for the association of intestinal metaplasia (IM) with chronic gastritis. We hypothesize that IM is correlated with the intensity of H. pylori infection in a country with high endemicity, Ivory Coast. The objective of this study was to determine the prevalence of intestinal metaplasia in chronic H. pylori gastritis in Ivory Coast. Methods: This was a prospective, cross-sectional, multicenter study, carried out over a period of 5 months, in the reference hospital centers of Abidjan, specialized in Gastroenterology. All patients who had undergone Gastroscopy with biopsies according to the criteria of the Sydney System for the anatomopathological study, those with chronic gastritis and/or H. pylori intestinal metaplasia on histology and in whom all the parameters of the Sydney system classification had been well informed. The quantitative variables were expressed by their means accompanied by their standard deviations and the qualitative variables by their numbers and percentages. Chi-square and Fischer tests were used to look for associations between variables. The significance level was set at 5%. Results: 152 patients were retained. The mean age was 44.9 ± 12.9 years. The prevalence of intestinal metaplasia was 11.8%. In univariate analysis, no significant association was found between clinical and pathological sociodemographic factors (age, sex, ethnicity, educational level, profession) and intestinal metaplasia in chronic Helicobacter pylori gastric cases. In multivariate analysis we found that prolonged use of Proton Pump Inhibitors (PPIs) and a history of Gastroesophageal Reflux Disease (GERD) were significantly associated with the absence of IM. Conclusion: Chronic H. pylori gastritis is the main risk factor for intestinal metaplasia. Prolonged use of PPIs and a history of GERD were significantly iden

关键词： Helicobacter Pylori Chronic Gastritis Intestinal Metaplasia Ivory Coast

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Aseptic Pseudoarthrosis of Olecranon: Epidemiological Features and Therapeutic Assessment

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Open Journal of Orthopedics 2017年第4期7卷 117-125页

作者： Raphael Dallo Gogoua Moctar Traoré Bi yao Armand Yépié Maurice kouamé Michel Anoumou Department of Orthopaedic Surgery and Traumatology C.H.U. Treichville Abidjan Cote d’Ivoire

Introduction: Pseudoarthrosis is one of the most dreadful complications of olecranon fractures. It seriously compromises the function of the elbow. Objectives: To determine the epidemiological factors of this complication in order to prevent them and to assess the results of the therapeutic management. Material and method: This was a retrospective study that involved patients with olecranon pseudoarthrosis who were treated in the department between January 2006 and December 2016. The diagnosis of pseudoarthrosis was made at least 6 months after the management of the fracture. There were 16 men and 5 women. We analyzed the epidemiological factors, the treatment of pseudoarthrosis, and the postoperative outcome. Results: The incriminated factors were the complexity of the fracture line and the quality of treatment of the recent fracture. The osteosynthesis of pseudoarthrosis is similar to that of recent fractures. It requires in some cases a bone graft. The results of the treatment are satisfactory with 100% of consolidation, and a good functional result in 75% of the cases. Conclusion: The treatment of olecranon pseudoarthrosis is based above all on prevention by an optimal management of the recent fractures. The curative treatment gives satisfactory functional results.

关键词： Fracture Pseudoarthrosis Olecranon Elbow

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Major Limb Amputation Secondary to Locally Advanced Cutaneous Squamous Cell Carcinoma in Tropical Environments: Determinants

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Open Journal of Orthopedics 2018年第4期8卷 139-147页

作者： Kouassi kouamé Jean Eric yao Loukou Blaise Sery Bada Justin Leopold Niaoré M’bra kouamé Innocent Krah Koffi Léopold Kouassi Aya Adelaide Nathacha Assere yao Aboh Ganyn Robert Arnaud Kodo Michel Trauma and Orthopedics Department Bouake Teaching Hospital Bouake Ivory Coast

Objective: To identify the determinants of secondary limb amputation in advanced squamous cell carcinoma. Material and Methods: This was a retrospective study carried out in the Orthopedic Traumatology Department of the Bouaké University Hospital in Côte d’Ivoire from January 2013 to December 2016. It involved ten patients with locally advanced skin squamous cell carcinoma, confirmed by histology and having amputated limbs. The parameters studied were: demographic data (gender, age), socio-economic conditions (occupation, place of residence), the risk factors involved, the use of topical self-medication and the use of traditional medicine, antecedents and comorbidities factors, lifestyle, clinical aspects (seat, size), extension assessment (X-ray), anatomo-pathological examination data, duration of evolution of squamous cell carcinoma, the function of the affected limb, the treatment performed, the evolutionary modalities and the equipment. Results: Between 2013 and 2016, ten patients underwent either upper or lower limb amputations following locally advanced squamous cell carcinoma. The average age was 34.1 years (19 - 64 years). There were 7 men (70%) and 3 women (30%) and all our patients were black (sub-Saharan Africa). The majority of our patients were farmers (70%). The risk factors for squamous cell carcinoma were neglected chronic wounds. All our patients recognized during the interrogation a large use of the topicals of traditional medicine for the treatment of the initial cutaneous lesions. In terms of lifestyle, five (50%) were smokers and alcoholics. The mean time to progression of squamous cell carcinoma was 5.9 years. Lesions were localized preferentially to the pelvic limbs six (60%) cases and four (40%) to the limbs chest. The lesion was diagnosed late in all our patients. The size of the tumor in all our patients was greater than 5 cm and had a deep invasion (nerves, vessels and bone). The proximal ipsilateral ganglionic invasion was constant.

关键词： Amputation Squamous Cell Carcinoma Cutaneous Histology

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Unsaturated Flow Drying Bed(UFDB):An Alternative for Treatment of Septic Tanks Sludge

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Journal of Water Resource and Protection 2014年第5期6卷 454-462页

作者： Gnagne Théophile Yéo Ténénan Martial kouamé yao Francis Konan Koffi Félix Faculty of Science and Environmental Management University Nangui AbrogouaAbidjanCote d’Ivoire Water and Sanitation for Africa National Representation of Cote d’IvoireAbidjanCote d’Ivoire Faculty of Environment University Jean Lorougnon GUEDE of DaloaDaloaCote d’Ivoire

Unsaturated Flow Drying Bed (UFDB) principles are based on the ones of wastewater treatment by infiltration-percolation on the one hand and septic tanks sludge solar-drying beds on the other hand. With UFDB, sludge charges are split with low heights, leading to the drying of suspended solids in 2 days, and the infiltration of the flow of liquid in unsaturated middle. For average charges reaching 12.5 cm/d, the treatment efficiency of total oxygen demand and Total Kjeldahl Nitrogen, respectively 95 and 96%, correspond to a treatment capacity of 0.5 kg of O2/d/m2 of drying area. Bacteria reductions of 4 Ulog are obtained from filtrates outlet, with average fecal coliforms charges less than 103 CFU/100 ml. Monitoring the hydrodynamic behavior through rates, moisture, organic matter and respiratory activity demonstrates that the clogging of the massifs is linked to a biofilm growth within them. A four week resting period allows biofilm resorption. Thus, the drying of the infiltration surface in two days, the elimination of carbon, nitrogen and bacterial pollutions, as well as the reversibility of clogging show that UFDB is a credible alternative for the treatment of septic tank sludge in the socio-economic context and climate of tropical Africa.

关键词： Sludge Clogging Drying Bed Unsaturated Zone Aeration Pores

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Anti-arthritic effect of Distemonanthus benthamianus extracts against rheumatoid arthritis in rats

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Asian Pacific Journal of Tropical Biomedicine 2022年第10期12卷 411-420页

作者： William Yousseu Nana Ernest Allah Hoki Kwenteh Gilbert Ateufack Eric Gonzal Tsafack Stephanie FloreDjuichou Nguemnang Zenab Linda Fagni Njoya albert Donatien Atsamo Vanessa Mba Matah Marthe CarineFlore Adjouzem Yacine Karelle Madjo kouam Elvira Ngoufack Azanze Marius Mbiantcha Laboratory of Biology and Physiology of Animal Organisms Department of Biology of Animal OrganismsFaculty of ScienceThe University of Douala CameroonP.O.Box 24157DoualaCameroon Research Unit of Animal Physiology and Phytopharmacology Faculty of ScienceUniversity of DschangDschangCameroon Laboratory of Animal Physiology Faculty of ScienceUniversity of Yaounde IYaoundéCameroon

Objective:To evaluate the anti-arthritic effect of aqueous and methanolic extracts of Distemonanthus ***:Monoarthritis was induced by an injection of 0.3 mL zymosan A(0.9%NaCl,v/v)in the right posterior knee joints of ***,joint diameter and pain threshold were *** was induced by an intracaudal injection of complete Freund’s adjuvant and rats were treated from day 14 post 1st complete Freund’s adjuvant injection until 28 *** clinical,hematological,biochemical and oxidative stress parameters were *** addition,histological analysis of the knee joint was perfomed in both ***:The aqueous and methanolic extracts of Distemonanthus benthamianus at a dose of 500 mg/kg ameliorated zymosan A-induced monoarthritis,as evidenced by reduced joint diameter,increased pain threshold,as well as improved joint *** addition,both extracts of Distemonanthus benthamianus markedly increased body weight and pain threshold,while reducing paw edema in polyarthritic *** also led to a marked decrease in platelets and white blood cells(P<0.05),as well as a significant increase in red blood cells,hemoglobin and hematocrit(P<0.05).The aqueous and methanolic extracts of Distemonanthus benthamianus significantly reduced alanine aminotransferase,aspartate aminotransferase,alkaline phosphatase activities,while increasing serum protein levels(P<0.05)with no significant variation in creatinine ***,both extracts increased catalase and glutathione activities(P<0.05),and inhibited malondialdehyde and nitric oxide production(P<0.01 and P<0.001)in the liver and *** analysis of the joints showed that both extracts triggered tissue ***:Distemonanthus benthamianus could be used as a potential candidate in the treatment of rheumatoid arthritis.

关键词： Distemonanthus benthamianus Rheumatoid arthritis Anti-arthritis Complete Freund’s adjuvant Hyperalgesia Inflammation Oxidative stress

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Spontaneous Rupture of Urinary Bladder (SRUB): An Exceptional Presentation

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Open Journal of Urology 2023年第9期13卷 376-381页

作者： Coulibaly Noël yao Evrard kouamé Adebayo Tawakaltu Bolasade Tuo Legnima Sekou Michel Yeo Donafologo Daouda Diomandé Vamoussa Service d’urologie CHU Treichville Abidjan C&#244te d’Ivoire Département de Chirurgie et Spécialités Chirurgicales Université Felix Houphou&#235t Boigny UFRSMA Cocody Abidjan C&#244te d’Ivoire

Background: Spontaneous rupture of urinary bladder (SRUB) without trauma is an extremely rare pathology. The incidence is estimated to about 1/126,000. It is difficult to diagnose. Aim: To present an exceptional case report and emphasize on the difficulty of diagnosis. Case Presentation: We report the case of a 63-year-old man. The initial diagnosis of SRUB was obscured by a urinary retention. The pelvic ultrasound finally led to the diagnosis. We will pay particular attention to the circumstances of the diagnosis and the therapeutic measures applied. Conclusion: SRUB is exceptional and misdiagnosis is usual. Management is most of the time surgical.

关键词： Bladder Rupture Spontaneous Rupture Treatment

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Intra Uterine Device (IUD) Migration into the Bladder. Diagnosis Issues and Management

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Open Journal of Urology 2023年第12期13卷 525-529页

作者： Coulibaly Noël yao Evrard kouamé Khume Stéphane Adebayo Tawakaltu Bolasade Diallo Abdoulaye Akobé Privat Département de Chirurgie et Spécialités Chirurgicales Université Felix Houphou&#235t Boigny UFRSMA Abidjan C&#244te d’Ivoire Service d’urologie CHU Treichville Abidjan C&#244te d’Ivoire Service de Gynéco-Obstétrique CHU Treichville Abidjan C&#244te d’Ivoire Service de Gynéco-Obstétrique CHU d’Angré Abidjan C&#244te d’Ivoire

Background: Intra uterine device (IUD) is commonly used as contraceptive procedure. A mislocation is possible and may reduce quality of life. Aim: This paper aims to present a rare case report and emphasize on the difficulty of diagnosis. Case Presentation: A 40-year-old woman had a history of IUD implantation after her last delivery. Six years later, she visited a doctor for a pelvic pain going on for a long period. The diagnosis of mislocated intra uterine device (IUD) was made using imaging techniques. Conclusion: A pelvic pain in a woman, going on for a long period, should evoke a migrated IUD. Thorough exploration and management are required.

关键词： Bladder Foreign Body Intra Uterine Device Cystoscopy

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Occurrence of Enterobacter sakazakii(Cronobacter)and Other Enterobacteriaceae in Commercial Powdered Infant Formula in Abidjan,Ivory Coast

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Food and Nutrition Sciences 2012年第6期3卷 822-826页

作者： Kouadio yao Nanga Yessé Zinzendorf Guichard Bohoua Kra Athanase Kouassi Amian Koua Luc Kouakou Kouadio Patrice kouamé Guillaume yao Loukou Department of Sciences and Food Technology University of Abobo-AdjaméAbidjanCote d’Ivoire Department of Microbiology National Laboratory of Public HealthAbidjanCote d’Ivoire Department of Bacteriology and Virology University of CocodyAbidjanCote d’Ivoire Deprtment of Hydrology and Public Health University of CocodyAbidjanCôte d’Ivoire Laboratory of Biology National Institut of Public HealthAbidjanCote d’Ivoire

To determine the occurrence of Enterobacter sakazakii and other Enerobateriaceae in commercial powdered infant formula (PIF), 185 packages of PIF from different manufacturers, supermarkets and drug-stores in Abidjan were analyzed. Ten g of sample was homogenized in 90 ml of buffered peptone water (PBW, Biorad, Paris) for further studies. Enterobacteriaceae (coliforms) were enumerated according to French Association of Standardization methods. E. sakazakii was detected according to Kandhai’s method. Bacteria were identified using API20 system. Thirty-eight samples (20.5%) were positive for Enterobacteriaceae. Twenty-four samples (13%) yielded Enterobacter sakazakii. Other Enterobacteriaceae isolated included Pantoea spp. 21 (11.5%), Klebsiella pneumoniae subsp. Pneumonia 8 (4.3%), Citrobacter diversus 1 (0.5%), Citrobacter freundii 1 (0.5%), Enterobacter cloacae 1 (0.5%), Salmonella reading 1 (0.5%), Serratia ficara 1 (0.5%) Serratia odorifera 1 (0.5%). This study is the first report to describe the contamination of PIF from Abidjan with E. sakazakii and several other Enterobacteriaceae that could be opportunistic pathogens. Therefore, well-controlled studies need to be conducted to assess the extent of risk associated with contaminated PIF for infants in Abidjan.

关键词： Enterobacteriaceae Enterobacter sakazakii Powedered Infant Formulat

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Magnesium Enhances the Hepatorenal Protective Effects of Lippia multiflora Aqueous Leaves Extract in Streptozotocin-Diabetic Rats

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Journal of Biosciences and Medicines 2023年第10期11卷 35-45页

作者： Yapo Fulgence Allo Viviane Jocelyne Zannou-Tchoko kouamé Hermann Yéboué Brou André Konan Jacques yao Datté Biology and Health Laboratory UFR Biosciences Félix Houphou&eumlt-Boigny University Abidjan C&ocircte d’Ivoire

Purpose: This study was conducted in order to evaluate the antidiabetic effects of the aqueous extract of Lippia multiflora supplemented with magnesium on some biochemical markers of the kidneys and liver in type 2 diabetic rats. Method: 7 groups of 4 STZ-diabetic rats received separately orally Glucophage® (Glu 10 mg/kg), the plant extract (LiMAE 200 - 600 mg/kg) and the plant extract supplemented with magnesium (LiMAE-Mg 200 - 600 mg/kg). After a daily treatment of 21 days, serum biochemical parameters were assayed in 16 hr-fasted rats. Results: Diabetes caused a significant (p Conclusion: The addition of magnesium to the extract of Lippia multiflora caused a greater reduction in the levels of urea, creatinine, ALT and AST increased in STZ-diabetic rats. Magnesium would therefore enhance the nephroprotective and hepatoprotective effects of Lippia multiflora in diabetic rats.

关键词： Lippia multiflora Diabetes Streptozotocin Nephroprotective Hepatoprotective

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