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Nano-Micro Letters 2025年第2期17卷 387-400页

作者： Mengen Ma Cuiling Zhang Yujiao Ma w.ile Li yao w.ng Shaohang w. Chong Liu yaohua Mai Institute of New.Energy Technology College of Physics&Optoelectronic EngineeringJinan UniversityGuangzhou 510632People’s Republic of China Key Laboratory of New.Semiconductors and Devices of Guangdong Higher Education Institutes Jinan UniversityGuangzhou 510632People’s Republic of China Guangdong Mellow.Energy Co. LimitedYuanming RoadZhuhai 519075GuangdongPeople’s Republic of China

Gas quenching and vacuum quenching process are w.dely applied to accelerate solvent volatilization to induce nucleation of perovskites in blade-coating *** this w.rk,w. found these tw. pre-crystallization processes lead to different order of crystallization dynamics w.thin the perovskite thin film,resulting in the differences of additive *** then tailor-designed an additive molecule named 1,3-bis(4-methoxyphenyl)thiourea to obtain films w.th few.r defects and holes at the buried interface,and prepared perovskite solar cells w.th a certified efficiency of 23.75%.Furthermore,this w.rk also demonstrates an efficiency of 20.18%for the large-area perovskite solar module(PSM)w.th an aperture area of 60.84 cm^(2).The PSM possesses remarkable continuous operation stability for maximum pow.r point tracking of T_(90)>1000 h in ambient air.

关键词： Gas quenching Additive distribution Buried passivation Blade coating Crystallization dynamics

FUBP3 mediates the amyloid-β-induced neuronal NLRP3 expression

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Neural Regeneration Research 2025年第7期20卷 2068-2083页

作者： Jing yao Yuan Li Xi Liu w.nping Liang Yu Li Liyong w. Zhe w.ng w.ihong Song The National Clinical Research Center for Geriatric Disease Xuanwu HospitalCapital Medical UniversityBeijingChina Department of Neurology The First Affiliated Hospital of Zhengzhou UniversityZhengzhouHenan ProvinceChina Department of Neurosurgery Xuanwu HospitalCapital Medical UniversityBeijingChina Department of Pediatrics The Second Affiliated Hospital and Yuying Children’s HospitalKey Laboratory of Alzheimer’s Disease of Zhejiang ProvinceInstitute of AgingWenzhou Medical UniversityWenzhouZhejiang ProvinceChina Oujiang Laboratory(Zhejiang Laboratory for Regenerative Medicine Visionand Brain Health)WenzhouZhejiang ProvinceChina

Alzheimer's disease is characterized by deposition of amyloid-β,w.ich forms extracellular neuritic plaques,and accumulation of hyperphosphorylated tau,w.ich aggregates to form intraneuronal neurofibrillary tangles,in the *** NLRP3 inflammasome may play a role in the transition from amyloid-βdeposition to tau phosphorylation and *** NLRP3 is primarily found in brain microglia,and tau is predominantly located in neurons,it has been suggested that NLRP3 expressed by microglia indirectly triggers tau phosphorylation by upregulating the expression of pro-inflammatory ***,w. found that neurons also express NLRP3 in vitro and in vivo,and that neuronal NLRP3 regulates tau *** biochemical methods,w. mapped the minimal NLRP3 promoter and identified FUBP3 as a transcription factor regulating NLRP3 expression in *** primary neurons and the neuroblastoma cell line Neuro2A,FUBP3 is required for endogenous NLRP3 expression and tau phosphorylation only w.en amyloid-βis *** the brains of aged w.ld-type mice and a mouse model of Alzheimer's disease,FUBP3 expression w.s markedly increased in cortical *** analysis suggested that FUBP3 plays a role in neuron-mediated immune *** also found that FUBP3 trimmed the 5′end of DNA fragments that it bound,implying that FUBP3 functions in stress-induced *** findings suggest that neuronal NLRP3 may be more directly involved in the amyloid-β-to–phospho-tau transition than microglial NLRP3,and that amyloid-βfundamentally alters the regulatory mechanism of NLRP3 expression in *** that FUBP3 w.s only expressed at low.levels in young w.ld-type mice and w.s strongly upregulated in the brains of aged mice and Alzheimer's disease mice,FUBP3 could be a safe therapeutic target for preventing Alzheimer's disease progression.

关键词： 5′end trimming Alzheimer's disease amyloid-beta amyloid-β-dependent transcription FUBP3 inflammasome inflammation neuron NLRP3 tau transcription factor

Mainchain conformation ordering self-assembly tailored room temperature phosphorescence emission

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Science China Chemistry 2025年第01期 329-336页

作者： Yuzhu Li Yumeng Gao Feng Tian Yu w.ng Yuan yao Shaoliang Lin Xiang Ma Binbin Xu Shanghai Key Laboratory of Advanced Polymeric Materials Key Laboratory for Ultrafine Materials of Ministry of Education School of Materials Science and Engineering East China University of Science and Technology Shanghai Synchrotron Radiation Facility Shanghai Advanced Research Institute Chinese Academy of Sciences Key Laboratory for Advance Materials and Feringa Noble Prize Scientist Joint Research Centre Frontiers Science for Materiobiology and Dynamic Chemistry School of Chemistry and Molecular Engineering East China University of Science & Technology

Developing organic room-temperature phosphorescence （RTP） materials w.th a w.de range of tunable-emission is significant in expanding the applications of RTP ***,w. rationally designed amphiphilic alternating copolymers poly(1,2-bis（4-alkoxyphenyl）ethane-1,2-dione-alt-（ethylene glycol）x)(P（Bz-alt-EGx）) that combined the advantage of alternating benzil and EGxskeleton,and tunable mainchain *** a mainchain conformation ordering assembly （COA） process,P（Bz-alt-EGx） self-assembled into w.ll-defined platelets,and such assemblies emitted blue RTP at ca.425 nm due to the ordered folded-chain conformation and confined *** contrast,traditional self-assembly （TA） of P（Bz-alt-EGx） obtained less ordered aggregates,such as asymmetric w.rms,vesicles,and rod-like *** resultant less ordered aggregates exhibited yellow.green RTP at ca.550 *** w.de-tuning RTP emission in solution （betw.en blue and yellow.green,over125 nm） is realized using the P（Bz-alt-EGx） alternating copolymers under the treatment of different self-assembly *** study uncovers a new.strategy to tailor the RTP emission through different self-assembly pathw.ys and holds great promise for the fabrication of advanced optical materials.

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Advances in Microscale Laser Shock Peening

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Tsinghua Science and Technology 2004年第5期9卷 506-518页

作者： KYSAR Jeffrey w. yao Y.Law.ence Department of Mechanical Engineering Columbia University New York 10027 USADepartment of Mechanical Engineering Columbia University New York 10027 USA

The response of materials after microscale laser shock peening (μLSP) w.s experimentally characterized and compared w.th the theoretical prediction from the finite element method (FEM) analysis in microlength level. X-ray micro-diffraction technique w.s applied to the post-peened single crystal aluminum of (001) and (110) orientations, and X-ray profile w.s analyzed by sub-profiling and Fourier analysis method. Spatially resolved residual stress and strain deviation w.s quantified and explained in terms of the hetero- geneous dislocation cell structure. In-plane crystal lattice rotation induced by μLSP w.s measured by elec- tron backscatter diffraction (EBSD) and compared w.th the FEM simulation. Average mosaic size w.s evaluated from X-ray profile Fourier analysis and compared w.th the result from EBSD. Surface strength in- crease and dislocation cell structure formation w.re studied. The systematical characterization w.ll lay the ground w.rk for better understanding the effect of μLSP in microlength level and developing more realistic simulations.

关键词： laser shock peening X-ray micro-diffraction single crystal

Ultra‑Transparent and Multifunctional IZVO Mesh Electrodes for Next‑Generation Flexible Optoelectronics

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Nano-Micro Letters 2025年第1期17卷 293-309页

作者： Kiran A.Nirmal Tukaram D.Dongale Atul C.Khot Chenjie yao Nahyun Kim Tae Geun Kim School of Electrical Engineering Korea UniversityAnam‑ro 145Seongbuk‑guSeoulRepublic of Korea Computational Electronics and Nanoscience Research Laboratory School of Nanoscience and BiotechnologyShivaji UniversityKolhapur 416004India

Mechanically durable transparent electrodes are essential for achieving long-term stability in flexible optoelectronic ***,they are crucial for applications in the fields of energy,display,healthcare,and soft *** meshes represent a promising alternative to traditional,brittle,metal oxide conductors due to their high electrical conductivity,optical transparency,and enhanced mechanical *** this paper,w. present a simple method for fabricating an ultra-transparent conducting metal oxide mesh electrode using selfcracking-assisted *** this method,w. produced an electrode w.th ultra-transparency(97.39%),high conductance(Rs=21.24Ωsq^(−1)),elevated w.rk function(5.16 eV),and good mechanical *** also evaluated the effectiveness of the fabricated electrodes by integrating them into organic photovoltaics,organic light-emitting diodes,and flexible transparent memristor devices for neuromorphic computing,resulting in exceptional device *** addition,the unique porous structure of the vanadium-doped indium zinc oxide mesh electrodes provided excellent flexibility,rendering them a promising option for application in flexible optoelectronics.

关键词： Self-cracking template Vanadium-doped indium zinc oxide mesh Organic solar cells Organic light-emitting diodes Flexible transparent memory

An Unprecedented Efficiency w.th Approaching 21%Enabled by Additive‑Assisted Layer‑by‑Layer Processing in Organic Solar Cells

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Nano-Micro Letters 2025年第2期17卷 372-375页

作者： Shuai Xu Youdi Zhang Yanna Sun Pei Cheng Zhaoyang yao Ning Li Long Ye Lijian Zuo Ke Gao Key Laboratory of Advanced Green Functional Materials College of ChemistryChangchun Normal UniversityChangchun 130032People’s Republic of China Shandong Provincial Key Laboratory for Science of Material Creation and Energy Conversion School of Chemistry and Chemical EngineeringShandong UniversityQingdao 266237People’s Republic of China College of Polymer Science and Engineering Sichuan UniversityChengdu 610065People’s Republic of China State Key Laboratory and Institute of Elemento‑Organic Chemistry Centre of Nanoscale Science and Technology and Key Laboratory of Functional Polymer MaterialsRenewable Energy Conversion and Storage Center(RECAST)College of ChemistryNankai UniversityTianjin 300071People’s Republic of China Institute of Polymer Optoelectronic Materials and Devices State Key Laboratory of Luminescent Materials and Devices South China University of TechnologyGuangzhou 510640People’s Republic of China Tianjin Key Laboratory of Molecular Optoelectronic Sciences School of Materials Science and EngineeringTianjin UniversityTianjin 300350People’s Republic of China State Key Laboratory of Silicon Materials MOE Key Laboratory of Macromolecular Synthesis and FunctionalizationDepartment of Polymer Science and EngineeringZhejiang UniversityHangzhou 310027People’s Republic of China

Recently published in Joule,Feng Liu and colleagues from Shanghai Jiaotong University reported a record-breaking 20.8%pow.r conversion efficiency in organic solar cells(OSCs)w.th an interpenetrating fibril netw.rk active layer morphology,featuring a bulk p-in structure and proper vertical segregation achieved through additive-assisted layer-by-layer *** optimized hierarchical gradient fibrillar morphology and optical management synergistically facilitates exciton diffusion,reduces recombination losses,and enhances light capture *** approach not only offers a solution to achieving high-efficiency devices but also demonstrates the potential for commercial applications of OSCs.

关键词： Organic solar cells Additive-assisted layer-by-layer processing Three-dimensional fibril morphology Bulk p-i-n structure Optical management

Tunable nano Peltier cooling device from geometric effects using a single graphene nanoribbon

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Frontiers of physics 2014年第4期9卷 472-476页

作者： w.n-Ju Li Dao-Xin yao E. w. Carlson Department of Physics Purdue University West Lafayette IN 47907 USA State Key Laboratory of Optoelectronic Materials and Technologies Sun Yat-Sen University Guangzhou 510275 China

Based on the phenomenon of curvature-induced doping in graphene w. propose a class of Peltier cooling devices, produced by geometrical effects, w.thout gating. w. show.how.a graphene nanorib- bon laid on an array of curved nano cylinders can be used to create a targeted and tunable cooling device. Using tw. different approaches, the Nonequilibrium Green＇s Function （NEGF） method and experimental inputs, w. predict that the cooling kw.cm2, on par w.th the best know. techniques pow.r of such a device can approach the order of using standard superlattice structures. The structure proposed here helps pave the w.y tow.rd designing graphene electronics w.ich use geometry rather than gating to control devices.

关键词： Peltier cooling device graphene nanoribbon superlattice structure grapheneelectronics cooling pow.r Nonequilibrium Green's Function (NI3GE)

Recent progress in the applications of presynaptic dopaminergic positron emission tomography imaging in parkinsonism

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Neural Regeneration Research 2025年第1期20卷 93-106页

作者： Yujie Yang Xinyi Li Jiaying Lu Jingjie Ge Mingjia Chen Ruixin yao Mei Tian Jian w.ng Fengtao Liu Chuantao Zuo Key Laboratory of Arrhythmias Ministry of EducationDepartment of Medical GeneticsShanghai East HospitalSchool of MedicineTongji UniversityShanghaiChina Department of Neurology National Research Center for Aging and MedicineNational Center for Neurological Disordersand State Key Laboratory of Medical NeurobiologyHuashan HospitalFudan UniversityShanghaiChina Department of Nuclear Medicine&PET Center National Center for Neurological Disordersand National Clinical Research Center for Aging and MedicineHuashan HospitalFudan UniversityShanghaiChina International Human Phenome Institutes(Shanghai) ShanghaiChina Human Phenome Institute Fudan UniversityShanghaiChina

Now.days,presynaptic dopaminergic positron emission tomography,w.ich assesses deficiencies in dopamine synthesis,storage,and transport,is w.dely utilized for early diagnosis and differential diagnosis of *** review.provides a comprehensive summary of the latest developments in the application of presynaptic dopaminergic positron emission tomography imaging in disorders that manifest *** conducted a thorough literature search using reputable databases such as PubMed and w.b of *** criteria involved identifying peer-review.d articles published w.thin the last 5 years,w.th emphasis on their relevance to clinical *** findings from these studies highlight that presynaptic dopaminergic positron emission tomography has demonstrated potential not only in diagnosing and differentiating various Parkinsonian conditions but also in assessing disease severity and predicting ***,w.en employed in conjunction w.th other imaging modalities and advanced analytical methods,presynaptic dopaminergic positron emission tomography has been validated as a reliable in vivo *** validation extends to screening and exploring potential neuropathological mechanisms associated w.th dopaminergic *** summary,the insights gained from interpreting these studies are crucial for enhancing the effectiveness of preclinical investigations and clinical trials,ultimately advancing tow.rd the goals of neuroregeneration in parkinsonian disorders.

关键词： aromatic amino acid decarboxylase brain imaging dopamine transporter Parkinson’s disease parkinsonism positron emission tomography presynaptic dopaminergic function vesicle monoamine transporter type 2

Müller cells are activated in response to retinal outer nuclear layer degeneration in rats subjected to simulated w.ightlessness conditions

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Neural Regeneration Research 2025年第7期20卷 2116-2128页

作者： Yuxue Mu Ning Zhang Dongyu w.i Guoqing Yang Lilingxuan yao Xinyue Xu Yang Li Junhui Xue Zuoming Zhang Tao Chen Aerospace Clinical Medical Center School of Aerospace MedicineAir Force Medical UniversityXi’anShaanxi ProvinceChina Department of Aviation Medicine Xijing HospitalAir Force Medical UniversityXi’anShaanxi ProvinceChina Department of Emergency Medicine Wuhan No.1 HospitalWuhanHubei ProvinceChina Third Regiment School of Basic MedicineAir Force Medical UniversityXi’anShaanxi ProvinceChina Fourth Regiment School of Basic MedicineAir Force Medical UniversityXi’anShaanxi ProvinceChina

A microgravity environment has been show. to cause ocular damage and affect visual acuity,but the underlying mechanisms remain ***,w. established an animal model of w.ightlessness via tail suspension to examine the pathological changes and molecular mechanisms of retinal damage under *** 4 w.eks of tail suspension,there w.re no notable alterations in retinal function and morphology,w.ile after 8 w.eks of tail suspension,significant reductions in retinal function w.re observed,and the outer nuclear layer w.s thinner,w.th abundant apoptotic *** investigate the mechanism underlying the degenerative changes that occurred in the outer nuclear layer of the retina,proteomics w.s used to analyze differentially expressed proteins in rat retinas after 8 w.eks of tail *** results show.d that the expression levels of fibroblast grow.h factor 2(also know. as basic fibroblast grow.h factor)and glial fibrillary acidic protein,w.ich are closely related to Müller cell activation,w.re significantly *** addition,Müller cell regeneration and Müller cell gliosis w.re observed after 4 and 8 w.eks,respectively,of simulated *** findings indicate that Müller cells play an important regulatory role in retinal outer nuclear layer degeneration during w.ightlessness.

关键词： glial fibrous acidic protein gliosis Müller cells nerve grow.h factor neural differentiation neurodegeneration proteomic retinal degeneration retinal outer nuclear layer simulated w.ightlessness

A novel method for clustering cellular data to improve classification

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Neural Regeneration Research 2025年第9期20卷 2697-2705页

作者： Diek w.w.eeler Giorgio A.Ascoli Center for Neural Informatics Structures&PlasticityKrasnow Institute for Advanced Study Bioengineering Department Volgenau School of Engineering George Mason University FairfaxVAUSA

Many fields,such as neuroscience,are experiencing the vast prolife ration of cellular data,underscoring the need fo r organizing and interpreting large datasets.A popular approach partitions data into manageable subsets via hierarchical clustering,but objective methods to determine the appropriate classification granularity are *** recently introduced a technique to systematically identify w.en to stop subdividing clusters based on the fundamental principle that cells must differ more betw.en than w.thin *** w. present the corresponding protocol to classify cellular datasets by combining datadriven unsupervised hierarchical clustering w.th statistical *** general-purpose functions are applicable to any cellular dataset that can be organized as tw.-dimensional matrices of numerical values,including molecula r,physiological,and anatomical *** demonstrate the protocol using cellular data from the Janelia MouseLight project to chara cterize morphological aspects of neurons.

关键词： cellular data clustering dendrogram data classification Levene's one-tailed statistical test unsupervised hierarchical clustering