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Spatio-temporal variations of Arctic amplification and their linkage with the Arctic oscillation

Acta Oceanologica Sinica 2017年第8期36卷 42-51页

作者： wang yanshuo HUANG Fei FAN Tingting Physical Oceanography Laboratory/CIMST Ocean University of ChinaQingdao 266100China Qingdao National Laboratory for Marine Science and Technology Qingdao 266200China Ningbo Collabrative Innovation Center of Nonlinear Harzard System of Ocean and Atmosphere Ningbo UniversityNingbo 315211China

The Arctic near-surface air temperatures are increasing more than twice as fast as the global average-a feature known as Arctic amplification （AA）. A modified AA index is constructed in this paper to emphasize the contrast of warming rate between polar and mid-latitude regions, as well as the spatial and temporal characteristics of AA and their influence on atmospheric circulation over the Northern Hemisphere. Results show that AA has a pronounced annual cycle. The positive or negative phase activities are the strongest in autumn and winter, the weakest in summer. After experiencing a remarkable decadal shift from negative to positive phase in the early global warming hiatus period, the AA has entered into a state of being enlarged continuously, and the decadal regime shift of AA in about 2002 is affected mainly by decadal shift in autumn. In terms of spatial distribution, AA has maximum warming near the surface in almost all seasons except in summer. Poleward of 20~N, AA in autumn has a significant influence on the atmospheric circulation in the following winter. The reason may be that the autumn AA increases the amplitude of planetary waves, slows the wave speeds and weakens upper-level zonal winds through the thermal wind relation, thus influencing surface air temperature in the following winter. The AA correlates to negative phase of the Arctic oscillation （AO） and leads AO by 0-3 months within the period 1979-2002. However, weaker relationship between them is indistinctive after the decadal shift of AA.

关键词： Arctic amplification Arctic oscillation decadal shift mid-latitude

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Predict new cases of the coronavirus 19;in Michigan,*** other countries using Crow-AMSAA method

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Infectious Disease Modelling 2020年第1期5卷 459-477页

作者： yanshuo wang Data Mining and Reliability Consultant LLLW LLC Inc.P.O Box 25124LansingMI48909USA

Statistical predictions are useful to predict events based on statistical *** data is useful to determine outcomes based on inputs and *** Crow-AMSAA method will be explored to predict new cases of Coronavirus 19(COVID19).This method is currently used within engineering reliability design to predict failures and evaluate the reliability *** author intents to use this model to predict the COVID19 cases by using daily reported data from Michigan,New York City,U.S.A and other *** piece wise Crow-AMSAA(CA)model fits the data very well for the infected cases and deaths at different phases during the start of the COVID19 *** slope b of the Crow-AMSAA line indicates the speed of the transmission or death *** traditional epidemiological model is based on the exponential distribution,but the Crow-AMSAA is the Non Homogeneous Poisson Process(NHPP)which can be used to modeling the complex problem like COVID19,especially when the various mitigation strategies such as social distance,isolation and locking down were implemented by the government at different places.

关键词： COVID19 Prediction Modeling Crow-AMSAA NHPP Infected cases Deaths

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Aluminum induced crystallization of strongly (111) oriented polycrystalline silicon thin film and nucleation analysis

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Science China(Technological Sciences) 2010年第11期53卷 3002-3005页

作者： HUANG TianMao CHEN NuoFu ZHANG Xingwang BAI YiMing YIN ZhiGang SHI HuiWei ZHANG Han wang Yu wang yanshuo YANG XiaoLi Key Laboratory of Semiconductor Materials Science Institute of SemiconductorsChinese Academy of SciencesBeijing 100083China School of Renewable Energy North China Electric Power UniversityBeijing 102206China State Key Lab of Silicon Materials Zhejiang UniversityHangzhou 310027China

A polycrystalline silicon thin film was fabricated on glass substrate by means of aluminum induced crystallization (AIC). Al and α-Si layers were deposited by magnetron sputtering respectively and annealed at 480°C for 1 h to realize layer exchange. The polycrystalline silicon thin film was continuous and strongly (111) oriented. By analyzing the structure variation of the oxidation membrane and lattice mismatch between γ-Al2O3 and Si, it was concluded that aluminum promoted the formation of (111) oriented silicon nucleus by controlling the orientation of γ-Al2O3, which was formed at the early stage of annealing.

关键词： polycrystalline silicon thin film aluminum induced crystallization (111)preferred orientation

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Improved performance of GaAs-based micro-solar cell with novel polyimide/SiO_2/TiAu/SiO_2 structure

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Science China(Technological Sciences) 2011年第4期54卷 830-834页

作者： BAI YiMing wang Jun wang Yu ZHANG Han CHEN NuoFu YAO JianXi HUANG TianMao wang yanshuo ZHANG Xingwang WU JinLiang New and Renewable Energy of Beijing Key Laboratory North China Electric Power UniversityBeijing 102206China National Engineering Research Center for Optoelectronic Devices Institute of SemiconductorsChinese Academy of SciencesBeijing 100083China Key Laboratory of Semiconductor Materials Science Institute of SemiconductorsChinese Academy of SciencesBeijing 100083China

A novel interconnected structure consisting of a conventional polyimide layer(PM) and an additional SiO2/TiAu/SiO2 sandwich multilayer has been firstly proposed for improving the performance of GaAs micro-solar cell *** specific experimental investigations on the array with 108 unit cells have demonstrated that the novel structure of PM/SiO2/TiAu/SiO2 can effectively enhance the open-circuit voltage from 75 to 84 V and the fill factor from 35% to 57%.The performance improvement of our devices can be attributed to two ***,the TiAu shielding film can prevent the incident light from penetrating into the GaAs substrate so as to induce the serious substrate leakage ***,the compact texture of SiO2 in the novel structure can reduce the perimere recombination due to the crackle or shrinkage of *** is indicated that the novel structure can distinctly reduce the leakage current and improve output characteristic of micro-solar cells.

关键词： micro-solar cell SI-GaAs leakage current insulating layer

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Enhancing hydrogen evolution and oxidation kinetics through oxygen insertion into nickel lattice

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Journal of Energy Chemistry 2024年第8期95卷 529-539,I0012页

作者： Wanli Liang Xiyu Gong Jinchang Xu Zixuan Dan Fanyan Xie Hulei Yu Hao-Fan wang yanshuo Jin Hongjuan wang Yonghai Cao Hui Meng Hao Yu School of Chemistry and Chemical Engineering South China University of TechnologyGuangzhou 510641GuangdongChina Siyuan Laboratory Guangzhou Key Laboratory of Vacuum Coating Technologies and New Energy MaterialsGuangdong Provincial Engineering Technology Research Center of Vacuum Coating Technologies and New Energy MaterialsGuangdong Provincial Key Laboratory of Optical Fiber Sensing and CommunicationsDepartment of PhysicsJinan UniversityGuangzhou 510632GuangdongChina GBA Branch of Aerospace Information Research Institute Chinese Academy of SciencesGuangzhou 510700GuangdongChina Instrumental Analysis&Research Center Sun Yat-sen UniversityGuangzhou 510275GuangdongChina School of Materials Science and Engineering South China University of TechnologyGuangzhou 510641GuangdongChina

Nickel-based materials,including metallic Ni and Ni oxide,have been widely studied in the exploration of non-precious-metal hydrogen electrocatalysts,but neither pure Ni nor NiO is ideal for the hydrogen evolution reaction(HER)and hydrogen oxidation reaction(HOR).In this paper,an oxygen insertion strategy was applied on nickel to regulate its hydrogen electrocatalytic performance,and the oxygen-inserted nickel catalyst was successfully obtained with the assistance of tungsten dioxide support(denoted as O-Ni/WO_(2)).The partial insertion of oxygen in Ni maintains the face-centered cubic arrangement of Ni atoms,simultaneously expanding the lattice and increasing the lattice ***,the adsorption strength of^(*)H and^(*)OH on Ni is optimized,thus resulting in superior electrocatalytic performance of0-Ni/WO_(2)in alkaline HER/*** Tafel slope of O-Ni/WO_(2)@NF for HER is 56 mV dec^(-1),and the kinetic current density of O-Ni/WO_(2)for HOR reaches 4.85 mA cm^(-2),which is ahead of most currently reported *** proposed strategy of inserting an appropriate amount of anions into the metal lattice could provide more possibilities for the design of high-performance catalysts.

关键词： Hydrogen evolution Hydrogen oxidation Nickel Oxygen insertion Adsorption free energy

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Helicobacter pylori and immunotherapy for gastrointestinal cancer

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The Innovation 2024年第2期5卷 51-60页

作者： Keren Jia Yang Chen Yi Xie Xicheng wang Yajie Hu Yu Sun yanshuo Cao Liyan Zhang Yakun wang Zhenghang wang Zhihao Lu Jian Li Xiaotian Zhang Lin Shen Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing) Department of Gastrointestinal OncologyPeking University Cancer Hospital&InstituteBeijing 100142China Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing) Department of PathologyPeking University Cancer Hospital&InstituteBeijing 100142China

Helicobacter pylori infection is associated with the risk of gastrointestinal(GI)cancers;however,its impact on immunotherapy for GI cancers remains *** this study,we included 10,122 patients who underwent ^(13)C-urea breath *** 636 patients with Epstein-Barr virus–negative microsatellite-stable gastric cancer(GC)who were treated with anti-PD-1/PD-L1 therapy,***–positive patients exhibited significantly longer immune-related progression-free survival(irPFS)compared with ***–negative patients(6.97 months versus 5.03 months,p<0.001,hazard ratio[HR]0.76,95%confidence interval[CI]0.62–0.95,p=0.015).Moreover,the ***–positive group demonstrated a trend of 4 months longer median immune-related overall survival(irOS)than the ***–negative ***–positive GC displayed higher densities of PD-L1+cells and nonexhausted CD8+T cells,indicative of a“hot”tumor *** analysis revealed that ***–positive GC shared molecular characteristics similar to those of immunotherapy-sensitive ***,***–positive patients with DNA mismatch repair–deficient(dMMR)/microsatellite instability–high(MSI-H)colorectal adenocarcinoma and esophageal squamous cell carcinoma(ESCC)had shorter irPFS compared with ***–negative patients(16.13 months versus not reached,p=0.042,HR 2.26,95%CI 1.13–4.50,p=0.021 and 5.57 months versus 6.97 months,p=0.029,HR 1.59,95%CI 1.14–2.23,p=0.006,respectively).The difference in irOS between ***–positive and–negative patients had the same trend as that between dMMR/MSI-H colorectal adenocarcinoma and ESCC *** also identified a trend of shorter irPFS and irOS in ***–positive liver cancer and pancreatic cancer *** summary,our findings supported that *** infection is a beneficial factor for GC immunotherapy by shaping hot tumor ***,in dMMR/MSI-H colorectal adenocarcinoma and ESCC patients,*** adversely affects the efficacy of immunothera

关键词： immunotherapy gastrointestinal pylori

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Clinical efficacy and identification of factors confer resistance to afatinib(tyrosine kinase inhibitor)in EGFR-overexpressing esophageal squamous cell carcinoma

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Signal Transduction and Targeted Therapy 2024年第7期9卷 3130-3140页

作者： Yanni wang Chang Liu Huan Chen Xi Jiao Yujiao wang yanshuo Cao Jian Li Xiaotian Zhang Yu Sun Na Zhuo Fengxiao Dong Mengting Gao Fengyuan wang Liyuan Dong Jifang Gong Tianqi Sun Wei Zhu Henghui Zhang Lin Shen Zhihao Lu Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing) Department of Gastrointestinal OncologyPeking University Cancer Hospital and InstituteBeijingChina Genecast Biotechnology Co. LtdWuxiPR China State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers Beijing Key Laboratory of Carcinogenesis and Translational ResearchDepartment of Gastrointestinal OncologyPeking University Cancer Hospital and InstituteBeijingChina Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education) Department of PathologyPeking University Cancer Hospital and InstituteBeijingChina Precision Scientific(Beijing)Co. Ltd.BeijingChina Generulor Company Bio-X Lab ZhuhaiGuangdongChina Biomedical Innovation Center Beijing Shijitan HospitalCapital Medical UniversityBeijingChina Beijing Key Laboratory for Therapeutic Cancer Vaccines Beijing Shijitan HospitalCapital Medical UniversityBeijingChina

Epidermal growth factor receptor(EGFR)is reportedly overexpressed in most esophageal squamous cell carcinoma(ESCC)patients,but anti-EGFR treatments offer limited survival *** preclinical data showed the promising antitumor activity of afatinib in EGFR-overexpressing *** proof-of-concept,phase II trial assessed the efficacy and safety of afatinib in pretreated metastatic ESCC patients(n=41)with EGFR overexpression(NCT03940976).The study met its primary endpoint,with a confirmed objective response rate(ORR)of 39%in 38 efficacy-evaluable patients and a median overall survival of 7.8 months,with a manageable toxicity *** analysis of pretreatment tumors revealed that neurotrophic receptor tyrosine kinase 2(NTRK2)was negatively associated with afatinib sensitivity and might serve as a predictive biomarker,irrespective of EGFR ***,knocking down or inhibiting NTRK2 sensitized ESCC cells to afatinib *** study provides novel findings on the molecular factors underlying afatinib resistance and indicates that afatinib has the potential to become an important treatment for metastatic ESCC patients.

关键词： esophageal squamous expressing

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Bringing Opportunities Job fair connects Chinese-invested enterprises in South Africa with local job seekers

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ChinAfrica 2024年第5期16卷 40-41页

作者： NI yanshuo 不详

Simphiwe Zondi in Johannesburg,South Africa,was especially happy on 16 *** the 2024 Job Fair of the Chinese-Invested Enterprises in South Africa held in the Gallagher Convention Centre on that day,he presented his CV and immediately secured a job as a technical director at the South Africa subsidiary of PowerChina,which ranked 105th on the Fortune Global 500 list in *** was one of the few applicants who signed employment contracts at the job fair.

关键词： invested Fortune enterprises

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Forgeron des futurs Un salon de l'emploi connecte les entreprises chinoises en Afrique du Sud avec les chercheurs d'emiploi locaux

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中国与非洲（法文版） 2024年第5期16卷 40-41页

作者： NI yanshuo 不详

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烷氧自由基引发1,5-氢原子转移实现C(sp^(3))—H键官能团化的研究进展

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有机化学 2024年第1期44卷 1-17页

作者：朱彦硕王红言舒朋华张克娜王琪琳许昌学院食品与药学院河南许昌461000 河南大学化学与分子科学学院河南开封475004 许昌学院继续教育学院河南许昌461000

分子内氢原子转移(HAT)是实现远程C(sp^(3))—H键官能化的有效方法.烷氧自由基作为有机合成中的重要中间体,其参与的分子内氢原子转移反应一直倍受关注.特别是随着可见光催化技术的发展,在温和条件下就可以生成烷氧自由基,为烷氧自由基... 详细信息

分子内氢原子转移(HAT)是实现远程C(sp^(3))—H键官能化的有效方法.烷氧自由基作为有机合成中的重要中间体,其参与的分子内氢原子转移反应一直倍受关注.特别是随着可见光催化技术的发展,在温和条件下就可以生成烷氧自由基,为烷氧自由基引发的远程C(sp^(3))—H键官能团化反应提供了新的平台.综述了近五年来烷氧基自由基产生的不同方法及其引发的分子内1,5-HAT反应在C(sp^(3))—H键官能团化方面的研究进展.

关键词：可见光催化烷氧自由基远程官能团化 1,5-氢原子转移

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