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手术后间断使用或持续长期使用斯达汀对大血管手术患者心脏转归的影响

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麻醉与镇痛 2008年第4期4卷 7-14页

作者： yannick le manach Gilles Godet Pierre Coriat Claire Martinon Michèle Bertrand Marie-Hélène Fléron Bruno Riou 康茵(译) 王庆(译) 赵国栋(校) Departments of Anesthesiology and Critical Care Emergency Medicine and Surgery Centre Hospitalier Universitaire Pitié-SalpētrièreAssistance-Publique H6pitaux de Paris Universit6 Pierre et Marie Curie-Paris 6 Paris France 不详

背景斯达汀可降低非手术人群的心脏并发症，手术患者也可能受益。本研究旨在观察与间断使用者比较，大血管手术后持续使用斯达汀患者的心脏转归有无差异。方法对前瞻性收集的肾下型主动脉手术患者的资料进行研究，分析斯达汀治疗和围手... 详细信息

背景斯达汀可降低非手术人群的心脏并发症，手术患者也可能受益。本研究旨在观察与间断使用者比较，大血管手术后持续使用斯达汀患者的心脏转归有无差异。方法对前瞻性收集的肾下型主动脉手术患者的资料进行研究，分析斯达汀治疗和围手术期心脏并发症的相关性。2001年1月至2003年12月，临床尚无围手术期持续使用斯达汀的指南（间断使用组，n=491）。2004年1月制定指南推荐手术后尽早开始斯达汀持续治疗（持续使用组，n=178）。分析心肌坏死（定义为肌钙蛋白Ⅰ增高〉99百分位数或0．2ng/ml）的发生情况。组内（倾向性评分）和组间（lee评分）均进行风险调整。结果间断使用组和持续使用组手术后重新使用斯达汀治疗的时间间隔中位数分别为4天和1天（P〈0．001）。采用倾向性评分对手术前斯达汀治疗的可能性进行匹配，结果显示，手术后早期使用斯达汀和未早期使用（持续使用组与间断使用组）对手术后心肌坏死风险的比值比（OR）分别为0．38和2．1（相对危险度降低5．4倍，95％可信区间：1．2—25．3，P〈0．001）。经lee评分调整后OR在持续使用组为0．38，间断使用组为2．1（相对危险度降低5．5倍，95％可信区间：1．2～26．0，P〈0．001）。手术后斯达汀停药（〉4天）是手术后心肌坏死的独立预测因素（OR2．9，95％可信区间：1．6—5．5）。结论大血管手术后间断使用斯达汀与手术后心脏风险增高相关，建议大血管手术后尽早使用斯达汀。

关键词：大血管手术心脏并发症手术后转归相对危险度降低持续使用持续治疗心肌坏死

Massive Epistaxis Revealing a Post-Traumatic Aneurysm of the Internal Carotid Artery: A Clinical Case and Review of the Literature

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International Journal of Otolaryngology and Head & Neck Surgery 2024年第2期13卷 120-125页

作者： yannick Mossus Maguy Mbede Roger Meva’a Biouélé leonel Atanga Adèle-Rose Ngo Nyeki Pierre Ongolo Zogo François Djomou Alexis Ndjolo Department of Ophthalmology ENT and Stomatology Faculty of Medicine and Biomedical Sciences University of Yaoundé 1 Yaoundé Cameroon Department of Medical Imaging Faculty of Medicine and Biomedical Sciences University of Yaoundé 1 Yaoundé Cameroon

Internal carotid artery (ICA) aneurysms are an unusual but serious cause of epistaxis. This epistaxis is massive and sometimes uncontrollable threatening the vital prognosis of patients. We report the case of a 16-year-old adolescent received in emergency with severe bilateral epistaxis, asthenia and grade-3 left exophthalmos. In his history, the subject had been the victim of an assault six months before consultation. He had received blows on the cephalic extremity with light but repeated epistaxis. The treatment consisted to blood products transfusion and local compression by sterile gazes. An ICA aneurysm in sphenoid sinus has been confirmed in a craniofacial CT scan coupled to vascular opacification. Although the ICA has a variable course in contact with the sphenoid sinus, massive epistaxis would be the consequence of a pronounced dehiscence of the ICA in the sphenoid sinus, particularly in a traumatic context. In front of this type of epistaxis in our context, general practitioners must be able to suspect a ruptured ICA aneurysm in the presence of exophthalmos and a notion of old or recent cranio-encephalic injury. Additionally, due to the high morbidity and mortality of this condition, a monitoring algorithm is necessary for patients with head trauma to facilitate early detection.

关键词： Aneurysm Internal Carotid Artery Head Trauma Epistaxis

Spallation Process of Thermally Grown Oxides by In-Situ CCD Monitoring Technique

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Journal of Iron and Steel Research International 2009年第6期16卷 90-94页

作者： QI Yu-hong Philippe Lours yannick le Maoult Materials Science and Engineering Department Dalian Maritime University Dalian 116026 Liaoning China Research Centre on Tools Materials and Processes Ecole des Mines 81013 Albi France

In cooling process of Fe-Cr-Al alloy oxidized at 1 300 ℃, the effect of cooling speed and exposure time on oxide spalled area fraction and successive variety of the spalled region were studied by investigating evolvement of the thermally grown oxide using in-situ CCD monitoring technique. The results showed that oxide spallation can be restrained by controlling cooling speed and the critical temperature drop of spallation initiation which is closely related to the oxide thickness or exposure time, and the spallation process of a little region may be described in more detail as two routes： from the oxide/substrate interface micro-decohesion, micro-buckles, buckle spreading, buckle crack to spallation and from the interface micro-decohesion, micro-buckles, buckle crack and spallation to the residual oxide decohesion and spallation.

关键词： in-situ CCD monitoring technique spallation thermally grown oxide Fe-Cr-AI

Massive Epistaxis Revealing a Post-Traumatic Aneurysm of the Internal Carotid Artery:A Clinical Case and Review of the Literature

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A self-stabilised walking gait for humanoid robots based on the essential model with internal states

International Journal of Otolaryngology and Head & Neck Surgery（耳鼻喉） 2024年第2期 120页

作者： yannick Mossus Maguy Mbede RogerMeva’aBiouélé leonel Atanga Adèle-Rose Ngo Nyeki Pierre Ongolo Zogo François Djomou Alexis Ndjolo

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IET Cyber-Systems and Robotics 2022年第4期4卷 283-297页

作者： Qiuyue Luo Christine Chevallereau Yongsheng Ou Jianxin Pang Victor De-león-Gómez yannick Aoustin Shenzhen Institutes of Advanced Technology Chinese Academy of SciencesShenzhenChina Research Institute of UBTech Robotics ShenzhenChina Laboratoire des Sciences du Numerique de Nantes(LS2N) CNRSCentrale NantesNantes UniversitéNantesFrance FCA at the Univerdidad Autónoma de Coahuila TorreónMéxico

Walking stability is one of the key issues for humanoid robots.A self-stabilised walking gait for a full dynamic model of humanoid robots is *** simplified models,that is,the linear inverted pendulum model and variable-length inverted pendulum model,self-stabilisation of walking gait can be obtained if virtual constraints are properly *** result is extended to the full dynamic model of humanoid robots by using an essential dynamic model,which is developed based on the zero dynamics *** the proposed method,a robust stable walking for a humanoid robot is achieved by adjusting the step timing and landing position of the swing foot automatically,following its intrinsic dynamic *** exempts the robot from the time-consuming high-level control approaches,especially when a full dynamic model is *** different walking patterns/features(i.e.,the swing foot motion,the vertical centre of mass motion,the switching manifold configuration,etc.)affect the stability of the walking gait is *** are conducted on robots Romeo and TALOS to support the results.

关键词： dynamic stability humanoid and bipedal locomotion passive walking

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热生长陶瓷薄膜在压应力作用下的脱落行为

稀有金属材料与工程 2009年第S2期38卷 1150-1153页

作者：齐育红 Philippe Lours yannick le Maoult 张宗宝大连海事大学 Research Centre on Tools Materials & ProcessesEcoledes Mines

采用表面压痕技术和CCD监测技术研究了PM2000Fe-Cr-Al高温合金热生长氧化物陶瓷薄膜在压应力作用下的脱落行为。结果表明,表面压痕法产生的压痕周围裂纹区域面积和裂纹宽度可定性表征氧化物陶瓷薄膜附着能力,裂纹区域面积越大或裂纹越... 详细信息

采用表面压痕技术和CCD监测技术研究了PM2000Fe-Cr-Al高温合金热生长氧化物陶瓷薄膜在压应力作用下的脱落行为。结果表明,表面压痕法产生的压痕周围裂纹区域面积和裂纹宽度可定性表征氧化物陶瓷薄膜附着能力,裂纹区域面积越大或裂纹越宽薄膜附着能力越差;采用CCD摄像技术可以测得氧化物陶瓷薄膜初试脱落温度及脱落区域的形貌、位置、面积等数据。为进一步理解氧化物陶瓷薄膜的脱落机制提供了更多的信息。

关键词：热生长陶瓷薄膜脱落表面压痕技术 CCD监测技术

Influence of"protective"symbionts throughout the different steps of an aphid-parasitoid interaction

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Current Zoology 2021年第4期67卷 441-453页

作者： Corentin Sochard Laura Bellec Jean-Christophe Simon yannick Outreman IGEPP INRAEInstitut AgroUniv Rennes35000RennesFrance IGEPP INRAEInstitut AgroUniv Rennes35650Le RheuFrance

Microbial associates are widespread in insects,some conferring a protection to their hosts against natural enemies like *** protective symbionts may affect the infection success of the parasitoid by modifying behavioral defenses of their hosts,the development success of the parasitoid by conferring a resistance against it or by altering life-history traits of the emerging ***,we assessed the effects of different protective bacterial symbionts on the entire sequence of the host-parasitoid interaction(i.e.,from parasitoid attack to offspring emergence)between the pea aphid,Acyrthosiphon pisum,and its main parasitoid,Aphidius ervi and their impacts on the life-history traits of the emerging *** test whether symbiont-mediated phenotypes were general or specific to particular aphid-symbiont associations,we considered several aphid lineages,each harboring a different strain of either Hamiltonella defensa or Regiella insecticola,two protective symbionts commonly found in *** found that symbiont species and strains had a weak effect on the ability of aphids to defend themselves against the parasitic wasps during the attack and a strong effect on aphid resistance against parasitoid *** parasitism resistance was mainly determined by symbionts,their effects on host defensive behaviors varied from one aphid-symbiont association to ***,the symbiotic status of the aphid individuals had no impact on the attack rate of the parasitic wasps,the parasitoid emergence rate from parasitized aphids nor the life-history traits of the emerging ***,no correlations between symbiont effects on the different stages of the host-parasitoid interaction was observed,suggesting no trade-offs or positive associations between symbiont-mediated *** study highlights the need to consider various sequences of the host-parasitoid interaction to better assess the outcomes of protective symbioses and understand the

关键词： Acyrthosiphon pisum defensive behaviors Hamiltonella defensa host-parasitoid interactions protective symbioses Regiella insecticola

Hardware Architecture of Polyphase Filter Banks Performing Embedded Resampling for Software-Defined Radio Front-Ends

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ZTE Communications 2012年第1期10卷 54-62,70页

作者： Mehmood Awan yannick le Moullec Peter Koch Fred Harris Technology Platforms Section Dept. of Electronic Systems Aalborg University Dept. of Electrical & Computer Engineering San Diego State University

In this paper, we describe resourceefficient hardware architectures for softwaredefined radio （SDR） frontends. These architectures are made efficient by using a polyphase channelizer that performs arbitrary sample rate changes, frequency selection, and bandwidth control. We discuss area, time, and power optimization for field programmable gate array （FPGA） based architectures in an Mpath polyphase filter bank with modified Npath polyphase filter. Such systems allow resampling by arbitrary ratios while simultaneously performing baseband aliasing from center frequencies at Nyquist zones that are not multiples of the output sample rate. A nonmaximally decimated polyphase filter bank, where the number of data loads is not equal to the number of M subfilters, processes M subfilters in a time period that is either less than or greater than the Mdataload ＇ s time period. We present a loadprocess architecture （LPA） and a runtime architecture （RA）（based on serial polyphase structure） which have different scheduling. In LPA, Nsubfilters are loaded, and then M subfilters are processed at a clock rate that is a multiple of the input data rate. This is necessary to meet the output time constraint of the down-sampled data. In RA, Msubfilters processes are efficiently scheduled within Ndataload time while simultaneously loading N subfilters. This requires reduced clock rates compared with LPA, and potentially less power is consumed. A polyphase filter bank that uses different resampling factors for maximally decimated, underdecimated, overdecimated, and combined upand downsampled scenarios is used as a case study, and an analysis of area, time, and power for their FPGA architectures is given. For resourceoptimized SDR frontends, RA is superior for reducing operating clock rates and dynamic power consumption. RA is also superior for reducing area resources, except when indices are prestored in LUTs.

关键词： SDR FPGA Digital Frontends Polyphase Filter Bank Embedded Resampling

Polyphase Filter Banks for Embedded Sample Rate Changes in Digital Radio Front-Ends

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ZTE Communications 2011年第4期9卷 3-9页

作者： Mehmood Awan yannick le Moullec Peter Koch Fred Harris Technology Platforms Section Dept. of Electronic Systems Aalborg University Denmark Dept. of Electrical & Computer Engineering San Diego State UniversityCA USA

This paper presents efficient processing engines for software-defined radio （SDR） front-ends. These engines, based on a polyphase channelizer, perform arbitrary sample-rate changes, frequency selection, and bandwidth control. This paper presents an M-path polyphase filter bank based on a modified N-path polyphase filter. Such a system allows resampling by arbitrary ratios while performing baseband aliasing from center frequencies at Nyquist zones that are not multiples of the output sample rate. This resampling technique is based on sliding cyclic data load interacting with cyclic-shifted coefficients. A non-maximally-decimated polyphase filterbank （where the number of data loads is not equal to the number of M subfilters） processes M subfilters in a time period that is less than or greater than the M data loads. A polyphase filter bank with five different resampling modes is used as a case study for embedded resamp/ing in SDR front-ends. These modes are （i） maximally decimated, （ii） Under-decimated, （iii） over-decimated, and combined up- and down-sampling with （iv） single stride length, and （v） multiple stride lengths. These modes can be used to obtain any required rational sampling rate change in an SDR front-end based on a polyphase channelizer. They can also be used for translation to and from arbitrary center frequencies that are unrelated to the output sample rates.

关键词： SDR digital front-ends polyphase filter bank embedded resampling