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Usage of Chinese Herbs in Cancer patients in Southern china:A Survey

Chinese Journal of Integrative Medicine 2021年第7期27卷 502-508页

作者： XIONG Shao-quan CHEN Yu wang Li-juan LYU pan-pan LIAO Wan wang Cui KE Jian-long ZHU Xi wang Jin-yang SHEN Xian-ying LI Guang-ping LIN Li-zhu department of Oncology Affiliated Hospital of Chengdu University of Traditional Chinese MedicineChengdu610000China department of Oncology Friendship Hospital of Sichuan Provincial People's HospitalSichuan ProvinceChengdu610000China department of Oncology Traditional Chinese Medicine Hospital of Shaanxi ProvinceShaanxi ProvinceXi'an710000China School of Clinical Medicine Chengdu University of Traditional Chinese MedicineSichuan ProvinceChengdu610075China State Key Laboratory of Characteristic Chinese Drug resources in Southwest china Chengdu University of Traditional Chinese MedicineChengdu611137China department of Oncology the First Affiliated Hospital of Guangzhou University of Traditional Chinese MedicineGuangzhou510405China

Objective To study the use of Chinese medicine(CM)in cancer patients in southern *** A total of 1,950 cancer patients finished questionnaires in four provinces in southern *** survey included socio-demographic and clinical characteristics of participants,dosage forms,efficacy,and side *** The study results showed that cancer patients with higher education(>12.years)were more likely to accept the treatment of Chinese *** were 54.61%(1,065 cases)of patients chose Chinese herbs for the initial treatment and 14.46%(2.2.cases)chose Chinese herbs as *** patients(54.51%,1,063 cases)continuously used CM for more than 6 months,and a few of them(2.2.cases)used CM for up to 3 *** kinds of dosage forms of CM had been used,including CM decoction,CM patent prescription and CM *** the efficacy in the view of patients,40.31%(786 cases)believed that it would be effective to take Chinese herbs before they starting the anti-cancer treatment,and the percentage increased to 81.08%after 1-month CM *** effect of Chinese herbs was mainly demonstrated by symptom relief and improvement of quality of life,and 8.31%(162.cases)of patients experienced control of tumor growth and decreased tumor ***,only 14.31%(2.9 cases)participants reported that they experienced side effects during CM *** This large scale investigation reflects the current situation of domestic CM usage objectively and comprehensively,which might provide new ways for cancer treatment.

关键词： Chinese medicine herbs cancer South china efficacy side and toxic effect

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The E3 ubiquitin ligase CSIT1 regulates critical sterility-inducing temperature by ribosome-associated quality control to safeguard two-line hybrid breeding in rice

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Molecular plant 2023年第10期16卷 1695-1709页

作者： Guoqing peng Minglong Liu Liya Zhu Wenlong Luo Qinghua wang Mumei wang Huiqiong Chen Ziliang Luo Yueping Xiao Yongjie Zhang Haona Hong Zhenlan Liu Lingyan Zhou Guoqiang Guo Yingxiang wang Chuxiong Zhuang Hai Zhou State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources Guangdong Laboratory for Lingnan Modern AgricultureKey Laboratory for Enhancing Resource Use Efficiency of Crops in South ChinaMinistry of Agriculture and Rural AffairsCollege of Life SciencesSouth China Agricultural UniversityGuangzhou 510642China College of Agriculture&Biology Zhongkai University of Agriculture and EngineeringGuangzhou 510225China Guangdong Key Laboratory for New Technology research of Vegetables Vegetable Research InstituteGuangdong Academy of Agricultural SciencesGuangzhou 510640China Agronomy department University of FloridaGainesvilleFL 32610USA Hengyang Academy of Agricultural Sciences Hengyang 421101China

Two-line hybrid breeding can fully utilize heterosis in *** thermo-sensitive genic male sterile(TGMS)lines,low critical sterility-inducing temperature(CSIT)is vital to safeguard the production of two-line hybrid seeds in rice(Oryza sativa),but the molecular mechanism determining CSIT is ***,we report the cloning of CSIT1,which encodes an E3 ubiquitin ligase,and show that CSIT1 modulates the CSIT of thermo-sensitive genic male sterility 5(tms5)-based TGMS lines through ribosome-associated quality control(rQC).Biochemical assays demonstrated that CSIT1 binds to the 80S ribosomes and ubiquitinates abnormal nascent polypeptides for degradation in the rQC *** of CSIT1 function inhibits the possible damage of tms5 to the ubiquitination system and protein translation,resulting in enhanced accumulation of anther-related proteins such as catalase to suppress abnormal accumulation of reactive oxygen species and premature programmed cell death in the tapetum,thereby leading to a much higher CSIT in the tms5-based TGMS *** together,our findings reveal a regulatory mechanism of CSIT,providing new insights into rQC and potential targets for future two-line hybrid breeding.

关键词： hybrid breeding thermo-sensitive genic male sterility critical sterility-inducing temperature ribosome-associated quality control programmed cell death

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Two Feasible Schemes for preparing Cluster States with Ion-Trap Setup

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Communications in Theoretical physics 2008年第5期49卷 1217-1220页

作者： wang Xin-Wen CAO Shuai XIA Li-Xin department of physics Hunan University of Science and Engineering Yongzhou 425100 China College of Science South China Agricultural University Guangzhou 510642 China department of physics Tsinghua University Beijing 100084 China

We present two schemes for preparing cluster states with atomic qubits in an ion-trap system. In the first scheme an auxiliary atomic level is needed. While in the second scheme an additional classical driven field is used, and the multi-ion cluster states can be generated by one step. Both the schemes are insensitive to thermal motion of the ions, all the facilities used in them are well within state of the art.

关键词： ion-trap cluster states one-step implementation controlled phase gates

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无创左室压力-应变环评估急性心肌梗死患者经皮冠状动脉介入术前后左心功能及左室重构的价值

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实用医学杂志 2024年第20期40卷 2841-2847页

作者：王歆赫叶创文童华生孟菲朱贤胜南方医科大学第一临床医学院广东广州510515 中国人民解放军南部战区总医院超声诊断科广东广州510010 中国人民解放军南部战区总医院重症医学科广东广州510010

目的探讨基于无创左室压力-应变环(LV-pSL)技术评估急性心肌梗死(AMI)患者经皮冠状动脉介入(pCI)术前、后的心肌做功情况及左室重构的临床价值。方法选择70例AMI患者(冠心病组)及同期体检的50例健康成人(对照组)。比较对照组和冠心病组... 详细信息

目的探讨基于无创左室压力-应变环(LV-pSL)技术评估急性心肌梗死(AMI)患者经皮冠状动脉介入(pCI)术前、后的心肌做功情况及左室重构的临床价值。方法选择70例AMI患者(冠心病组)及同期体检的50例健康成人(对照组)。比较对照组和冠心病组术前、术后7 d检查常规超声心动图指标、左室整体纵向应变(GLS)和左室心肌做功指标[整体做功指数(GWI)、整体做功效率(GWE)、整体有用功(GCW)、整体无用功(GWW)]的差异。冠心病组患者进一步根据冠脉造影结果分为冠心病单支组34例和冠心病多支组36例,对比两组上述指标的差异。分析左室心肌做功指标与GLS、常规超声心动图指标的相关性。结果冠心病组术前、术后7d左室收缩末期容积(LVESV)、左室舒张末期容积(LVEDV)、GWW均高于对照组,左室射血分数(LVEF)、GWI、GWE、GCW、GLS均低于对照组,差异均有统计学意义(pppppSL技术在评估AMI患者pCI术前、后左心功能及左室重构方面具有较好的应用价值,为临床急性心肌梗死患者经皮冠状动脉介入术术后提供了一种无创、有效的评估新方法。

关键词：心肌做功急性心肌梗死左心功能左室重构

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舰载航空发动机用GH2.50A压气机叶片的耐蚀性

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腐蚀与防护 2024年第7期45卷 24-28页

作者：王江张林嘉张安琴高军尹翔肖钦夤中国航发贵阳发动机设计研究所贵阳550081 海装广州局贵阳军代室贵阳550081

高温、高湿、高盐雾的海洋环境,给舰载航空发动机带来了严重的腐蚀风险。压气机是大气流经发动机的主要通道,其叶片直接受到高压、高速和潮湿海洋大气的冲刷和腐蚀,造成的损伤与失效尤为突出。根据某型舰载航空发动机高压压气机叶片的... 详细信息

高温、高湿、高盐雾的海洋环境,给舰载航空发动机带来了严重的腐蚀风险。压气机是大气流经发动机的主要通道,其叶片直接受到高压、高速和潮湿海洋大气的冲刷和腐蚀,造成的损伤与失效尤为突出。根据某型舰载航空发动机高压压气机叶片的服役条件,对GH2.50A和GH2.50A+化学钝化两种状态的高压压气机叶片进行了192.酸性盐雾试验、680h酸性大气腐蚀试验及100h,600℃涂盐热腐蚀试验。结果表明;两种状态的叶片都表现出良好的耐酸性盐雾和酸性大气腐蚀性能;然而,经过2.h涂盐热腐蚀试验后,两种叶片均出现红色腐蚀斑点,60h后整个叶片均被腐蚀,其中经过化学钝化的叶片经100h涂盐热腐蚀试验后,碱洗质量损失较原始叶片更小,表明化学钝化在一定程度可以阻碍腐蚀,但防护能力有限。

关键词： GH2.50A叶片腐蚀酸性盐雾酸性大气涂盐热腐蚀

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Catalytic conversion of lignocellulosic biomass into chemicals and fuels

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Green Energy & Environment 2023年第1期8卷 10-114页

作者： Weiping Deng Yunchao Feng Jie Fu Haiwei Guo Yong Guo Buxing Han Zhicheng Jiang Lingzhao Kong Changzhi Li Haichao Liu phuc T.T.Nguyen puning ren Feng wang Shuai wang Yanqin wang Ye wang Sie Shing Wong Kai Yan Ning Yan Xiaofei Yang Yuanbao Zhang Zhanrong Zhang Xianhai Zeng Hui Zhou State Key Laboratory for physical Chemistry of Solid Surfaces Collaborative Innovation Center of Chemistry for Energy MaterialsNational Engineering Laboratory for Green Chemical Productions of Alcohols-Ethers-Estersand College of Chemistry and Chemical EngineeringXiamen UniversityXiamen361005China Fujian Engineering and research Center of Clean and High-valued Technologies for Biomass Xiamen Key Laboratory of High-valued Utilization of BiomassCollege of EnergyXiamen University361102China Key Laboratory of Biomass Chemical Engineering of Ministry of Education College of Chemical and Biological EngineeringZhejiang UniversityHangzhou310027China Institute of Zhejiang University-Quzhou 78 Jiuhua Boulevard NorthQuzhou324000China School of Energy and Environmental Engineering Hebei University of TechnologyTianjin300401China Shanghai Key Laboratory of Functional Materials Chemistry Research Institute of Industrial CatalysisSchool of Chemistry and Molecular EngineeringEast China University of Science and TechnologyShanghai200237China Beijing National Laboratory for Molecular Sciences CAS Key Laboratory of Colloid and Interface and ThermodynamicsCAS Research/Education Center for Excellence in Molecular SciencesInstitute of ChemistryChinese Academy of SciencesBeijing100190China department of Biomass Science and Engineering Sichuan UniversityChengdu610065China CAS Key Laboratory of Low-carbon Conversion Science and Engineering Shanghai Advanced Research InstituteChinese Academy of SciencesShanghai201210China University of Chinese Academy of Sciences Beijing100049China CAS Key Laboratory of Science and Technology on Applied Catalysis Dalian Institute of Chemical PhysicsChinese Academy of SciencesDalian116023China Beijing National Laboratory for Molecular Sciences College of Chemistry and Molecular EngineeringPeking UniversityBeijing100871China department of Chemical and Biomolecular Engineering National University of Singapore4 Engineering Drive 4Singapore117585Singapore Sta

In the search of alternative resources to make commodity chemicals and transportation fuels for a low carbon future,lignocellulosic biomass with over 180-billion-ton annual production rate has been identified as a promising *** review focuses on the state-of-the-art catalytic transformation of lignocellulosic biomass into value-added chemicals and *** a brief introduction on the structure,major resources and pretreatment methods of lignocellulosic biomass,the catalytic conversion of three main components,i.e.,cellulose,hemicellulose and lignin,into various compounds are comprehensively *** in separate steps or in one-pot,cellulose and hemicellulose are hydrolyzed into sugars and upgraded into oxygen-containing chemicals such as 5-HMF,furfural,polyols,and organic acids,or even nitrogen-containing chemicals such as amino *** the other hand,lignin is first depolymerized into phenols,catechols,guaiacols,aldehydes and ketones,and then further transformed into hydrocarbon fuels,bioplastic precursors and bioactive *** review then introduces the transformations of whole biomass via catalytic gasification,catalytic pyrolysis,as well as emerging ***,opportunities,challenges and prospective of woody biomass valorization are highlighted.

关键词： Lignocelullose Biomass Catalytic conversion Biofuels renewable chemicals

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三级医院老年患者出院延续护理转介单的设计及应用

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护理学杂志 2024年第15期39卷 108-111页

作者：王琳黄瑞英牛亚荣刘敏林海华暨南大学附属第一医院延续护理服务部广东广州510630 暨南大学护理学院

目的设计三级医院老年患者出院延续护理转介单,评价其应用效果。方法参考文献资料,采用焦点小组讨论法,设计老年患者出院延续护理转介单,嵌入医院电子病历信息系统,病区护士使用转介单对有延续护理需求的患者进行转介,延续护理服务部专... 详细信息

目的设计三级医院老年患者出院延续护理转介单,评价其应用效果。方法参考文献资料,采用焦点小组讨论法,设计老年患者出院延续护理转介单,嵌入医院电子病历信息系统,病区护士使用转介单对有延续护理需求的患者进行转介,延续护理服务部专职护士接收转介,到病区为患者提供出院计划服务及出院后上门护理。结果2.2.-2.2.年全院2.个老年患者所在科室均应用老年患者出院延续护理转介单实施转介,转介患者386例,其中80岁及以上老年患者2.9例(56.7%),内科系统9个科室共转介患者2.7例(69.2.)。为386例患者出院后1个月内提供上门护理服务597例次,患者出院30 d内非计划性再入院率为5.2.。结论设计及应用老年患者出院延续护理转介单,有利于促进转介及提高不同部门工作人员之间合作协调性,从而满足出院老年患者延续护理服务需求及降低出院后非计划性再入院率。

关键词：三级医院老年患者出院护理延续护理转介单上门护理服务非计划性再入院

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Nanodrug enhances post-ablation immunotherapy of hepatocellular carcinoma via promoting dendritic cell maturation and antigen presentation

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Bioactive Materials 2023年第3期21卷 57-68页

作者： Zecong Xiao Tan Li Xinyao Zheng Liteng Lin Xiaobin wang Bo Li Jingjun Huang Yong wang Xintao Shuai Kangshun Zhu department of Minimally Invasive Interventional radiology And Laboratory of Interventional RadiologyThe Second Affiliated Hospital of Guangzhou Medical UniversityGuangzhou510260China Nanomedicine research Center The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhou510630China College of Chemistry and Materials Science Jinan UniversityGuangzhou510632China department of Dermatology The Nanfang Hospital of Southern Medical UniversityGuangzhouGuangdong510515China

Thermal ablation(TA)as an effective method treating hepatocellular carcinoma(HCC)in clinics is facing great challenges of high recurrence and *** immune-checkpoint blockade(ICB)-based immuno-therapy has shown potential to inhibit recurrence and metastasis,the combination strategy of ICB and thermal ablation has shown little progress in HCC *** tremendous hurdle for combining ICB with thermal ablation lies with the insufficient antigen internalization and immaturity of tumor-infiltrating dendritic cells(TIDCs)which leads to an inferior immune response to distant tumor growth and ***,an antigen-capturing nanoplatform,whose surface was modified with mannose as a targeting ligand,was constructed for co-delivering tumor-associated antigens(TAAs)and m6A demethylases inhibitor(i.e.,fat mass and obesity asso-ciated gene(FTO)inhibitor)into *** vivo results demonstrate that the intratumoral injection of nanodrug followed by HCC thermal ablation promotes dendritic cells(DCs)maturation,improves tumor infiltration of effector T cells and generates immune memory,which synergize with ICB treatment to inhibit the distant tumor growth and lung ***,the antigen-capturing and FTO-inhibiting nanodrug holds potential to boost the ICB-based immunotherapy against HCC after thermal ablation.

关键词： Thermal ablation Tumor-infiltrating dendritic cells N6-methyladenosine modification Nanoplatform Tumor immunotherapy

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3种构造形式调谐质量阻尼器性能

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同济大学学报（自然科学版） 2024年第9期52卷 1401-1408页

作者：吴思远廖旭钊荣坤杰王俊杰孔伟明傅知春鲁正同济大学土木工程防灾减灾全国重点实验室上海200092 大连理工大学建设工程学部辽宁大连116024 中国建筑第八工程局有限公司上海200122 智性科技南通有限公司江苏南通226000 广东省建筑设计研究院广东广州510010 山东大学土建与水利学院山东济南250062

提出了3种平面内自由运动的调谐质量阻尼器(TMD)构造形式,即十字形(CTMD)、X形(XTMD)和旋风形(TTMD),通过有限元模型对比分析了3种TMD刚度变化、模态和简谐激励振动响应。根据分析结果可知,当TMD激励方向与弹簧垂直时,弹簧出力表现出非... 详细信息

提出了3种平面内自由运动的调谐质量阻尼器(TMD)构造形式,即十字形(CTMD)、X形(XTMD)和旋风形(TTMD),通过有限元模型对比分析了3种TMD刚度变化、模态和简谐激励振动响应。根据分析结果可知,当TMD激励方向与弹簧垂直时,弹簧出力表现出非线性行为;相比于其他构造形式,TTMD减振效果更为稳定,效率更高。当质量比大于3%时,TTMD抑振效果更为显著。

关键词：调谐质量阻尼器十字形调谐质量阻尼器 X形调谐质量阻尼器旋风形调谐质量阻尼器力学行为动力特性

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A model for estimating flow assurance of hydrate slurry in pipelines

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Journal of Natural Gas Chemistry 2010年第4期19卷 380-384页

作者： Wuchang wang Shuanshi Fan Deqing Liang Yuxing Li department of Storage and Transportation Engineering China University of Petroleum Qingdao 266555 Shandong China South china university of Technology Key Laboratory of Enhanced Heat Transfer and Energy Conservation MOE Guangzhou 510640 Guangdong China guangzhou Institute of Energy Conversion Chinese Academy of Sciences Guangzhou 510640 Guangdong China

The problem of hydrate blockage of pipelines in offshore production is becoming ever-increasing severe because oil fields in ever-increasing unusual environments have been brought in ***-141b and THF were selected as the substitutes to study the flow assurance of the hydrates in *** are critical hydrate volume concentrations for these two *** slurries behave like Bingham fluids and have high agglomerating tendency when the hydrate volume concentrations are larger than the critical *** on rheological behaviors of these two hydrates,a non-dimensional parameter is proposed through studying the driving forces of agglomeration among hydrate particles,which shows the agglomerating probability of hydrate particles in pipeline and can be used to judge the safety of the ***,a safe model to judge the safely flow hydrate slurries was presented and verified with the experimental data,which demonstrates that the model is effective to judge whether the pipeline can be run safely or not.

关键词： hydrate slurry flow assurance rheological behavior safe model

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