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Acta Geochimica 2023年第5期42卷 879-894页

作者： Zhaode Xia Haibo Ding yanjiao ru School of Earth Science and Resources Chang’an UniversityXi’an 710054ShaanxiChina The Third Geological Branch Xinjiang Geological and Mineral BureauKuerleXinjiang 841000China Geophysical and Geochemical Exploration Corporation Bureau of Geological Exploration for Nonferrous Metals in Northwest ChinaXi’an 710068ShaanxiChina

The Dunde iron-zinc polymetallic deposit is one of large iron deposits occurred in the Awulale Metallogenetic Belt,Western Tianshan(NW-China).This study reports new geochronology and geochemistry for granite in the Dunde mining area in order to constrain the tectonicmagmatic activities and metallogenesis of this *** in the southwest of Dunde mining area are mainly syenogranites intruded into volcanics of the Dahalajunshan Formation in the Early Carboniferous,and they are far from the area where ore bodies and mineralized altered rocks are widely ***-ICP-MS U–Pb zircon dating indicates that Dunde syenogranite was at 306.8±1.0 Ma,which could constrain the upper limit of metallogenic age for this *** Dunde granites are high SiO_(2)(73.41–80.07 wt%),high differentiation index(D.I.=89.7–95.0),weakly peraluminous to metaluminous(A/CNK=0.94–1.08),and they are enriched in LILE and LREE and depleted in Eu,Ba,Sr and P_(2)O_(5),indicating that they belong to highly fractionated Ⅰ-type *** on εHf values(+9.2 to+10.5)for zircon and high εNd(-t)values(+4.7 to+5.8)for whole-rock,and the two-stage model ages for 601–735 Ma,suggest that the magma source could be the juvenile lower *** with regional geological setting,the 306.8 Ma Dunde granites are formed in post-collision extensional tectonic setting.

关键词： Granite Geochemistry Magma source Tectonic setting Dunde deposit Western Tianshan

Acquired sensorineural hearing loss,oxidative stress,and microRNAs

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Neural Regeneration Research 2025年第9期20卷 2513-2519页

作者： Desmond A.Nunez ru C.Guo Division of Otolaryngology–Head&Neck Surgery Department of SurgeryFaculty of MedicineThe University of British ColumbiaVancouverBCCanada Division of Otolaryngology–Head&Neck Surgery Gordon&Leslie Diamond Health Care CentreVancouver General HospitalVancouverBCCanada Faculty of Medicine–The University of British Columbia VancouverBCCanada

Hearing loss is the third leading cause of human ***-related hearing loss,one type of acquired sensorineural hearing loss,is largely responsible for this escalating global health ***-induced,ototoxic,and idiopathic sudden sensorineural are other less common types of acquired hearing *** etiology of these conditions is complex and multi-fa ctorial involving an interplay of genetic and environmental *** stress has recently been proposed as a likely linking cause in most types of acquired sensorineural hearing *** non-coding RNA sequences known as microRNAs(miRNAs)have increasingly been shown to play a role in cellular hypoxia and oxidative stress responses including promoting an apoptotic *** hair cell death is a central histopathological finding in sensorineural hearing *** these cells do not regenerate in humans,it underlies the irreversibility of human age-related hearing *** EMBASE,Ovid MEDLINE,Web of Science Core Collection,and *** databases over the period August 1,2018 to July 31,2023 were searched with"hearing loss,""hypoxamiRs,""hypoxia,""microRNAs,""ischemia,"and"oxidative stress"text words for English language primary study publications or registered clinical *** red clinical trials known to the senior author we re also assessed.A total of 222studies were thus *** excluding duplicates,editorials,retra ctions,secondary research studies,and non-English language articles,39 primary studies and clinical trials underwent full-text *** resulted in 11 animal,in vitro,and/or human subject journal articles and 8 registered clinical trial database entries which form the basis of this narrative *** miR-34a and miR-29b levels increase with age in *** miRNAs were demonstrated in human neuroblastoma and murine cochlear cell lines to target Sirtuin 1/peroxisome proliferato r-activated receptor gamma coactivator-1-alpha(SIRT1/P GC-1α),SIRT

关键词： hearing loss hypoxia microRNAs oxidative stress sensorineural

新疆昭苏县北高铝玄武岩时代、岩石学和地球化学特征——西天山早石炭世汇聚板块构造的标志

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地质通报 2021年第6期40卷 864-879页

作者：李智佩白建科茹艳娇李婷李晓英自然资源部岩浆作用成矿与找矿重点实验室陕西西安710054 中国地质调查局造山带地质研究中心/西安地质调查中心陕西西安710054 西安西北有色物化探总队有限公司陕西西安710068

西天山乌孙山南坡赛克散萨依一带出露的早石炭世杜内阶大哈拉军山组火山岩,LA-ICP-MS锆石U-Pb年龄为355.1+4.0 Ma。火山岩岩石类型主要为玄武岩和少量钠质粗面玄武岩(夏威夷岩),SiO_(2)含量为45.04%~49.84%,Na_(2)O含量为2.36%~4.63% ,K... 详细信息

西天山乌孙山南坡赛克散萨依一带出露的早石炭世杜内阶大哈拉军山组火山岩,LA-ICP-MS锆石U-Pb年龄为355.1+4.0 Ma。火山岩岩石类型主要为玄武岩和少量钠质粗面玄武岩(夏威夷岩),SiO_(2)含量为45.04%~49.84%,Na_(2)O含量为2.36%~4.63% ,K_(2)O含量为0.35%~2.31%,Na_(2)O/K_(2)O值为2.00~8.69,表明均属钠质火山岩;Al2O3含量集中在16.01%~17.15%之间,以偏碱性的高铝质玄武岩为主,有少量碱性玄武岩。火山岩稀土元素总量为94.71×10^(-6)~127.2×10^(-6),(La/Yb)N值为2.41~4.07,δEu值为0.99~1.15具有轻、重稀土元素分馏明显的右倾式配分型式。大离子亲石元素较洋脊玄武岩富集,存在明显的Th-U槽和Nb-Ta槽。高场强元素多数与洋脊玄武岩接近,TiO_(2)的亏损不显著,K_(2)O明显富集。玄武岩的演化具有典型的拉斑质玄武岩经分离结晶作用形成的铁富集演化趋势,且以辉石和斜长石为主要的分离结晶矿物,橄榄石的分离结晶作用不明显。高铝质玄武岩的确定是早石炭世伊犁地区中天山板块汇聚构造环境的标志,与现今高铝质火山岩产出构造环境对比认为,这些火山岩形成于大陆边缘岛弧,其构造位置可能为俯冲带上的第二火山链;火山岩浆则可能由俯冲带上流体交代的富集地幔部分熔融形成。

关键词：大哈拉军山组高铝玄武岩 LA-ICP-MS锆石U-Pb年龄地球化学构造环境西天山

西天山乌孙山地区大哈拉军山组火山岩岩石组合与喷发序列研究进展

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西北地质 2018年第4期51卷 33-42页

作者：茹艳娇李智佩白建科李婷夏昭德西安西北有色物化探总队有限公司陕西西安710068 长安大学地球科学与资源学院陕西西安710054 中国地质调查局西安地质调查中心陕西西安710054

新疆西天山地区伊犁地块南北缘以及地块内部广泛分布着大哈拉军山组火山岩系。笔者在前人研究基础上,以乌孙山一带出露的大哈拉军山组火山岩为主要研究对象,通过路线地质调查、剖面测制和岩相学等方面的系统研究,厘定了大哈拉军山组的... 详细信息

新疆西天山地区伊犁地块南北缘以及地块内部广泛分布着大哈拉军山组火山岩系。笔者在前人研究基础上,以乌孙山一带出露的大哈拉军山组火山岩为主要研究对象,通过路线地质调查、剖面测制和岩相学等方面的系统研究,厘定了大哈拉军山组的岩石组合、地层序列及其变化规律。大哈拉军山组火山岩总体由玄武岩、安山岩、英安岩、流纹岩,以及中酸性火山碎屑岩组成。乌孙山—塔斯巴山地区以安山岩为主,占50%,玄武岩、英安岩和流纹岩比例相近。火山岩地层喷发序列上,乌孙山—塔斯巴山一带底部为中酸性火山岩,向上为中基性与中酸性火山岩的交替喷发,可划分出5～7个喷发旋回,火山活动整体上具有裂隙式-中心式喷发的特征。

关键词：大哈拉军山组岩石组合喷发序列乌孙山西天山

Outcomes of a non-diffractive extended depth of focus intraocular lens in patients with well-controlled glaucoma and ocular hypertension

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International Journal of Ophthalmology(English edition) 2025年第1期18卷 79-85页

作者： Jia-ru Liu Andrei-Alexandru Szigiato Paul Harasymowycz Department of Ophthalmology University of MontrealQuebec H3T 1J4Canada Department of Ophthalmology Hôpital Sacré-CoeurQuebec H4J 1C5Canada Department of Ophthalmology Hôpital Maisonneuve-RosemontQuebec H1T 2M4Canada Bellevue Ophthalmology Clinics Quebec H1V 1G5Canada

AIM:To assess visual outcomes and satisfaction of a non-diffractive extended depth of focus(EDOF)intraocular lens(IOL)in individuals with ocular hypertension(OHT)and well-controlled mild glaucoma undergoing cataract ***:An investigator-initiated,single-center,prospective,interventional,noncomparative study conducted in Montreal,*** study enrolled 31 patients(55 eyes)with OHT or mild glaucoma who received a non-diffractive EDOF IOL(Acrysof IQ Vivity).Participants underwent sequential cataract surgery with the Vivity ***-up evaluations occurred at 1d,1,and 3mo postoperatively,assessing uncorrected distance,intermediate,and near visual ***(QUVID:Questionnaire for visual disturbances and IOLSAT:Intraocular lens satisfaction)were administered pre and post-operatively to measure visual disturbances and spectacle independence in various *** parameters included intraocular pressure(IOP),glaucoma medications,spherical equivalence,mean deviation and pattern standard deviation or square root of lost variance on Octopus visual ***:At 1 and 3mo postoperatively,significant improvements were observed in uncorrected distance and intermediate visual *** independence was enhanced for distance and intermediate vision,especially in bright light ***-free intermediate vision was improved even in dim *** disturbances,particularly glare symptoms,were reduced,and there was a notable decrease in IOP and glaucoma medication burden at *** was more hazy vision postoperatively with no impact on visual acuity and visual ***:The non-diffractive EDOF lens improves distance and intermediate spectacle-free visual function in patients with OHT and well-controlled *** findings highlight significant improvements in visual acuity,reduced glare,enhanced spectacle independence,and improved visual performance in different lighting conditions.

关键词： extended depth of focus refractive glaucoma ocular hypertension cataract intraocular lens

Smaller, faster, lower-power analog RRAM matrix computing circuits without performance compromise

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Science China(Information Sciences) 2025年第2期68卷 293-306页

作者： Yubiao LUO Pushen ZUO Shiqing WANG Zhong SUN ru HUANG School of Integrated Circuits Peking University Institute for Artificial Intelligence Peking University Beijing Advanced Innovation Center for Integrated Circuits

Recently, the analog matrix computing(AMC) concept has been proposed for fast, efficient matrix operations, by configuring global feedback loops with crosspoint resistive memory arrays and operational amplifiers(OAs). The implementation of a general real-valued matrix(containing both positive and negative elements) is enabled by using a set of analog inverters,which, however, is considered inefficient regarding circuit compactness, power consumption, and temporal response. Here, with the assistance of the conductance compensation(CC) strategy to take full advantage of the inherent differential inputs of OAs,new AMC circuits without analog inverters are designed. Such a design saves the area occupation and power dissipation of analog inverters, and thus turns to be smaller and lower-power. Simulation results reveal that the new circuit also shows a faster response towards the steady state, thanks to the reduction of poles in the circuit, which, again, is contributed by the elimination of analog inverters. Along with all of these benefits, extensive simulations demonstrate that the CC-AMC circuits do not compromise the computing performance in terms of relative error caused by various non-ideal factors in the circuit.

关键词： analog computing in-memory computing matrix resistive memory conductance compensation

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Fluorine-functionalized zirconium-organic cages for efficient photocatalytic oxidation of thioanisole

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Chinese Chemical Letters 2025年第1期36卷 632-636页

作者： Jia-ru Li Ning Li Li-Ling He Jun He School of Chemical Engineering and Light Industry Guangdong University of TechnologyGuangzhou 510006China School of Chemistry South China Normal UniversityGuangzhou 510006China

Zirconium-based metal-organic cages(Zr-MOCs)typically exhibit high stability,but their structural and application reports are scarce due to stringent crystallization *** have successfully fluorinated the classical Zr-MOCs(ZrT-3)for the first time,obtaining the fluorinated MOCs(ZrT-3-F).Notably,ZrT-3-F not only inherits the high stability of its parent structure,but also acts as a catalyst for the effective oxidation of benzyl thioether for the first *** reaction can reach a conversion rate of 99%in 6 h,and the selectivity reaches 95%,which far exceeds the non-fluorinated *** work proves that the specific functionalization of the classical Zr-MOCs can further expand their application potential,such as catalysis.

关键词： Ultraviolet light Fluorine Zirconium-based metal-organic cages Sulfide oxidation Multiphase photocatalysis

Efficient implementation of quantum permutation algorithm using a polar SrO molecule in pendular states

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Communications in Theoretical Physics 2025年第2期77卷 41-53页

作者： Jie-ru Hu Zuo-Yuan Zhang Jin-Ming Liu State Key Laboratory of Precision Spectroscopy School of Physics and Electronic Science East China Normal University School of Physical Science and Technology Yangzhou University Chongqing Key Laboratory of Precision Optics Chongqing Institute of East China Normal University

Quantum algorithms offer more enhanced computational efficiency in comparison to their classical counterparts when solving specific tasks. In this study, we implement the quantum permutation algorithm utilizing a polar molecule within an external electric field. The selection of the molecular qutrit involves the utilization of field-dressed states generated through the pendular modes of SrO. Through the application of multi-target optimal control theory, we strategically design microwave pulses to execute logical operations, including Fourier transform,oracle Ufoperation, and inverse Fourier transform within a three-level molecular qutrit *** observed high fidelity of our outcomes is intricately linked to the concept of the quantum speed limit, which quantifies the maximum speed of quantum state manipulation. Subsequently,we design the optimized pulse sequence to successfully simulate the quantum permutation algorithm on a single SrO molecule, achieving remarkable fidelity. Consequently, a quantum circuit comprising a single qutrit suffices to determine permutation parity with just a single function evaluation. Therefore, our results indicate that the optimal control theory can be well applied to the quantum computation of polar molecular systems.

关键词： polar molecule optimal control quantum permutation algorithm pendular states

On load dependence of detachment rate of kinesin motor

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Chinese Physics B 2025年第1期34卷 498-505页

作者： Xiao-Xuan Shi Yao Wang Yu-ru Liu Ping Xie School of Pharmaceutical Engineering Chongqing Chemical Industry Vocational CollegeChongqing 401220China Laboratory of Soft Matter Physics Institute of PhysicsChinese Academy of SciencesBeijing 100190China

Kinesin is an archetypal microtubule-based molecular motor that can generate force to transport cargo in cells. The load dependence of the detachment rate is an important factor of the kinesin motor, the determination of which is critically related to the chemomechanical coupling mechanism of the motor. Here, we use three models for the load dependence of the detachment rate of the kinesin motor to study theoretically and numerically the maximal force generated and microtubuleattachment duration of the motor. By comparing the theoretical and numerical results with the available experimental data,we show that only one model can explain well the available experimental data, indicating that only this model can be applicable to the kinesin motor.

关键词： kinesin detachment rate generated force chemomechanical coupling mechanism optical trapping

Enhancement of weathered crust elution-deposited rare earth ores leaching process with PQ-10 addition

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Journal of Rare Earths 2025年第1期43卷 180-190,I0007页

作者： Aoyang Sha Huifang Yang Zhengyan He Zhigao Xu Chenjie Wu Ming Wu ru'an Chi Key Laboratory of Catalysis and Energy Materials Chemistry of Ministry of Education Key Laboratory of Resources Conversion and Pollution Control of the State Ethnic Affairs Commission&Hubei Key Laboratory of Catalysis and Materials ScienceCollege of Resources and Environmental ScienceSouth-Central Minzu UniversityWuhan430074China Key Laboratory for Green Chemical Process of Ministry of Education School of Resources&Safety EngineeringWuhan Institute of TechnologyWuhan 430073China

To solve the problems of the long development period,low mass transfer efficiency and high impurity conte nt in the in-situ leaching process of weathe red crust elution-deposited rare earth ores(WCE-DREO),cationic hydroxyethyl cellulose(PQ-10)was composited with conventional leaching agent ammonium sulfate((NH_(4))_(2)SO_(4))to form a novel composite leaching *** effects of PQ-10 concentration,leaching temperature and leaching flow rate of the composite leaching agent on the leaching kinetics and mass transfer processes of rare earth(RE)and aluminum(Al)were *** to the single leaching agent(NH_(4))_(2)SO_(4),the composite leaching agent(2 wt%(NH_(4))_(2)SO_(4)+0.02 wt%PQ-10)can reduce the RE leaching equilibrium time from 465 to 130 min and increase the RE leaching efficiency and decrease the Al leaching *** also facilitates the leaching process of WCE-DREO by increasing the peak concentrations of RE and Al,reducing the theoretical tower plate height(HETP)and improving the leaching mass transfer *** is indicated that PQ-10 can promote the leaching of *** leaching process of the composite leaching system conforms to the diffusion kinetic control *** the PQ-10 concentration is in the range of 0.005 wt%-0.020 wt%,the reaction orders of RE and Al are 0.73 and 0.54,respectively,which shows a positive effect on the leaching velocity;when the PQ-10 concentration is in the range of 0.030 wt%-0.060 wt%,the reaction orders of RE and Al are-1.16 and-0.75,respectively,which show a negative effect on the leaching *** the range of 10-50℃,the apparent activation energies of RE and Al are 15.02 and 17.31 kJ/mol,respectively,and the higher the leaching temperature,the smaller the HETP and the higher the leaching velocity and mass transfer *** increase in leaching flow rate contributes to the increase in the longitudinal diffusion velocity of the leaching agent within WCE-DREO,causing a shorter time for RE

关键词： Cationic hydroxyethyl cellulose Weathered crust elution-deposited rare earthores Leaching Novel compositeagent