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Heat dissipation in graphene foams

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Nano Research 2021年第3期14卷 829-833页

作者： yaniv Cohen Siva K.Reddy Assaf Ya’akobovitz Department of Mechanical Engineering Faculty of Engineering SciencesBen-Gurion University of the NegevBeer-Sheva8410501Israel

Graphene foam(GF)—a three-dimensional network of hollow graphene branches—is a highly attractive material for diverse ***,to date,the heat dissipation characteristics of GFs have not been *** fill this gap,we synthesized GF devices,subjected them to high temperatures,and investigated their thermal behavior by using infrared *** find that while the convective area of GF devices is comparable to that of bulk materials(such as metals),the coefficient of convection of these devices is several orders of magnitude higher than that of *** addition,the GF devices showed a reproducible thermal behavior,which we attribute to negligible temperature-induced morphological changes(as confirmed by Raman analysis).Taken together,our findings suggest GF as a promising candidate material for advanced cooling applications where efficient heat dissipation is needed,e.g.,in electrical circuits.

关键词： convection graphene foam heat transfer

Glycogenic hepatopathy

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Hepatobiliary & Pancreatic Diseases International 2018年第2期17卷 113-118页

作者： Johad Khoury yaniv Zohar Naim Shehadeh Tarek Saadi Internal Medicine B Rambam Health Care Campus and Rappaport Faculty of Medicine Technion-Israel Institute of Technology Liver Unit Rambam Health Care Campus and Rappaport Faculty of Medicine Technion-Israel Institute of Technology Department of Pathology Rambam Health Care Campus and Rappaport Faculty of Medicine Technion-Israel Institute of Technology Meyer Children's Hospital of Haifa Rambam Health Care Campus and Rappaport Faculty of Medicine Technion-Israel Institute of Technology Institute of Diabetes Endocrinology and Metabolism Rambam Health Care Campus and Rappaport Faculty of Medicine Technion-Israel Institute of Technology Department of Gastroenterology Rambam Health Care Campus and Rappaport Faculty of Medicine Technion-Israel Institute of Technology

Background: Glycogenic hepatopathy(GH) is a disorder associated with uncontrolled diabetes mellitus,most commonly type 1, expressed as right upper quadrant abdominal pain, hepatomegaly and increased liver enzymes. The diagnosis may be difficult, because laboratory and imaging tests are not pathognomonic. Although GH may be suggested based on clinical presentation and imaging studies, the gold standard for diagnosis is a liver biopsy, showing a significant accumulation of glycogen within the hepatocytes. GH may be diagnosed also after elevated liver enzymes in routine blood tests. GH usually regresses after tight glycemic control. Progression to end-stage liver disease has never been reported. This review aims to increase the awareness to this disease, to suggest a pathway for investigation that may reduce the use of unnecessary tests, especially invasive *** sources: A Pub Med database search(up to July 1, 2017) was done with the words "glycogenic hepatopathy", "hepatic glycogenosis", "liver glycogenosis" and "diabetes mellitus-associated glycogen storage hepatopathy". Articles in which diabetes mellitus-associated liver glycogen accumulation was described were included in this ***: A total of 47 articles were found, describing 126 patients with GH. Hepatocellular disturbance was more profound than cholestatic disturbance. No synthetic failure was ***: GH may be diagnosed conservatively, based on corroborating medical history, physical examination, laboratory tests, imaging studies and response to treatment, even without liver biopsy. In case of doubt about the diagnosis or lack of clinical response to treatment, a liver biopsy may be *** is no role for noninvasive tests like fibroscan or fibrotest for the diagnosis of GH or for differentiation of this situation from nonalcoholic fatty liver disease.

关键词： Glycogenic hepatopathy Diabetes mellitus Hepatic glycogenosis Mauriac syndrome

Sniffing Bacteria with a Carbon-Dot Artificial Nose

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Nano-Micro Letters 2021年第7期13卷 138-152页

作者： Nitzan Shauloff Ahiud Morag Karin yaniv Seema Singh Ravit Malishev Ofra Paz-Tal Lior Rokach Raz Jelinek Department of Chemistry Ben Gurion University of the Negev84105 Beer ShevaIsrael Department of Biotechnology Engineering Ben Gurion University of the Negev84105 Beer ShevaIsrael Chemistry Department Nuclear Research CenterNegevP.O.Box 900184190 Beer ShevaIsrael Department of Software and Information System Engineering Ben-Gurion University of the NegevBeer ShevaIsrael Ilse Katz Institute for Nanotechnology Ben Gurion University of the Negev84105 Beer ShevaIsrael

Continuous,real-time monitoring and identification of bacteria through detection of microbially emitted volatile molecules are highly sought albeit elusive *** introduce an artificial nose for sensing and distinguishing vapor molecules,based upon recording the capacitance of interdigitated electrodes(IDEs)coated with carbon dots(C-dots)exhibiting different *** of the C-dot-IDEs to volatile molecules induced rapid capacitance changes that were intimately dependent upon the polarities of both gas molecules and the electrode-deposited *** deciphered the mechanism of capacitance transformations,specifically substitution of electrode-adsorbed water by gas molecules,with concomitant changes in capacitance related to both the polarity and dielectric constants of the vapor molecules *** C-dot-IDE gas sensor exhibited excellent selectivity,aided by application of machine learning *** capacitive C-dot-IDE sensor was employed to continuously monitor microbial proliferation,discriminating among bacteria through detection of distinctive“volatile compound fingerprint”for each bacterial *** C-dot-IDE platform is robust,reusable,readily assembled from inexpensive building blocks and constitutes a versatile and powerful vehicle for gas sensing in general,bacterial monitoring in particular.

关键词： Carbon dots Bacterial detection Bacterially emitted volatile molecules Capacitive gas sensors Gas polarity

Skull base chordomas review of current treatment paradigms

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World Journal of Otorhinolaryngology-Head and Neck Surgery 2020年第2期6卷 125-131页

作者： Dan yaniv Ethan Soudry Yulia Strenov Marc A.Cohen Aviram Mizrachi Department of Otolaryngology-Head and Neck Surgery Rabin Medical CenterPetah Tikva and Sackler Faculty of MedicineTel Aviv UniversityTel AvivIsrael Department of Pathology Rabin Medical CenterPetah Tikva and Sackler Faculty of MedicineTel Aviv UniversityTel AvivIsrael Head and Neck Service Department of SurgeryMemorial Sloan-Kettering Cancer CenterNew YorkNYUSA

Background:Chordomas are locally invasive neoplasms,arising from notochordal remnants and can appear anywhere along the axial *** recurrences are common,and distant metastases may occur years after the initial ***:Literature review of current treatment strategies for chordomas of the skull ***:Surgery is the mainstay of treatment and complete resection has paramount importance for *** complete resection is not achieved recurrent disease is *** anatomical complexity of the skull base makes resection *** endoscopic approaches to the clivus has become increasingly favored in recent years although addressing reconstruction of the skull base to prevent CSF leak may be *** suggests that radiotherapy should not be considered as a primary single modality when trying to achieve cure of the ***,immediate post-operative radiotherapy improves *** strategies have been suggested to preserve sensitive vital structures in the skull base during treatment but as for survival there is no evidence of advantage when comparing adjuvant therapy with photon radiotherapy,gamma knife surgery,proton beam therapy,and carbon ion radiation *** is no evidence to support cytotoxic chemotherapy in the treatment of chordomas but targeted therapies have started to show *** optional molecular targets *** is overexpressed in 95%of chordomas but not in other mesenchymal ***,its precise role in chordoma pathogenesis is currently unclear,and its cellular location in the nucleus makes it difficult to *** inhibition of brachyury in chordoma cell lines induces growth arrest and *** does not have clinical application to *** are retrospective results with different molecular targeted therapies for advanced chordomas with some ***:Despite improvements made in the past 10 years in our knowledge of chordoma bio

关键词： Skull Base Chordoma Surgery Review Targeted therapy

Interobserver and intraobserver agreement for Letournel acetabular fracture classification system using 3-dimensional printed solid models

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World Journal of Orthopedics 2021年第2期12卷 82-93页

作者： Eran Keltz Doron Keshet Eli Peled Yoav Zvi Doron Norman yaniv Keren Division of Orthopedic Surgery Rambam Health Care CampusHaifa 3525408Israel Ruth Rappaport Faculty of Medicine Technion Israel Institute of TechnologyHaifa 3200003Israel Department of Orthopaedic Surgery Montefiore Medical CenterNew YorkNY 10461United States

BACKGROUND Acetabular fractures pose diagnostic and surgical *** are classified using the Judet-Letournel system,which is based solely on ***,computed tomography(CT)imaging is now more widely utilized in diagnosing these *** emergence of 3-dimensional(3-D)printing technology in varying orthopedic fields has provided surgeons a solid model that improves their spatial understanding of complex fractures and ability to plan *** To evaluate the reliability of the Judet-Letournel classification system of acetabular fractures,when using either CT imaging or 3-D printed *** Seven patients with acetabular fractures underwent pelvic CT imaging,which was then used to create solid,3-D printed *** orthopaedic trauma surgeons responded to questionnaires regarding fracture classification and preferred surgical *** same questionnaire was completed using only CT imaging,and two weeks later,using only 3-D printed *** inter-and intra-observer agreement rates were then *** Inter-observer agreement rates based on CT imaging or 3-D printed models were moderate for fracture classification:κ=0.44,κ=0.55,respectively(P<0.001)and fair for preferred surgical approach:κ=0.34,κ=0.29,respectively(P<0.005).Intra-observer agreement rates for fracture classification and preferred surgical approach comparing CT imaging or 3-D printed models were moderate:κ=0.48,κ=0.41,*** significant difference in intra-observer agreement was detected when comparing orthopedic pelvic specialists to general orthopedic *** The Judet-Letournel classification demonstrated only moderate rates of *** use of 3-D printed models increased the inter-observer agreement rates with respect to fracture classification,but decreased it with respect to the preferred surgical *** study highlights the role of 3-D printed models in acetabular fractures by improving spatial understandin

关键词： Acetabulum Pelvic trauma Acetabular fracture Three-dimensional printing Three-dimensional reconstruction Judet-Letournel

When should we give up on expectant management for patients with proximal ureteral stones?

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Laser Treatment of Epistaxis and Oral Bleeding in Hereditary Hemorrhagic Telangiectasia

当代泌尿学（英文） 2022年第1期16卷 9-14页

作者： Igal Shpunt Etay Elbaz Yuval Avda Jonathan Modai Dan Leibovici Brian Berkowitz yaniv Shilo Department of Urology Kaplan Medical CenterRehovotIsrael Department of Earth and Planetary Sciences Weizmann Institute of ScienceRehovotIsrael

Background:Proximal ureteral stones(PUS)have relatively low rates of spontaneous ***,some patients do on expectant *** aim was to compare risk factors for surgical intervention in patients with PUS who underwent primary intervention to those subjected to expectant management.Materials and methods:We retrospectively reviewed the medical charts of patients presented to the emergency room with symptoms of renal colic and underwent computerized tomography between August 2016 and August 2017.A total of 97 consecutive patients were identified with up to 10 mm *** collected patient demographics,clinical,and imaging data,and performed binary regression analysis for risk of intervention.Results:The average age was 49years(range 17-97)and average stone size was 7.1 mm(range 3-10).Forty-one patients underwent immediate intervention while the remaining 56 patients were treated *** the 56 patients treated conservatively,26 underwent delayed intervention while 30 reported spontaneous stone *** univariate analysis of all 97 patients,statistically significant risk factors for intervention were found based on stone size,age,serum lymphocyte,platelet counts,and stone *** these risk factors,stone size≥7mm(p=0.012,odds ratio=5.4)and platelet count?230K/mL(p=0.027,odds ratio=4.9)remained statistically significant on multivariate analysis.Conclusion:Stone size and platelet count were found to be risk factors for surgical intervention in patients with up to 10 mm *** findings may assist in identifying patients who are more suitable for conservative approach.

关键词： Nephrolithiasis Renal colic Ureteral calculi Ureterolithiasis Urolithiasis

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International Journal of Otolaryngology and Head & Neck Surgery 2019年第5期8卷 180-190页

作者： Dan yaniv Uri Alkan Eitan yaniv Calin Bumbulut Lea Rath-Wolfson Department of Otorhinolaryngology-Head and Neck Surgery Rabin Medical CenterBeilinson HospitalPetach TikvaIsrael Sackler Faculty of Medicine Tel Aviv UniversityTel AvivIsrael Civil Medical Society Satu MareRomania Department of Pathology Rabin Medical CenterHasharon HospitalPetach TikvaIsrael

Background: Hereditary hemorrhagic telangiectasia (HHT) is a relatively common, albeit under-recognized autosomal-dominant multisystemic vascular disorder. Epistaxis due to telangiectases in the nasal mucosa is the most common and often the earliest symptom of HHT. As many as 90% of affected individuals eventually experience recurrent epistaxis, with a mean frequency of 18 episodes per month. Prompted by the limitations of invasive treatment, researchers have directed attention to laser photocoagulation as an alternative nonsurgical treatment modality with promising results. Purpose: The purpose of the present study was to describe our experience with the state-of-the-art 980 nm diode laser for the treatment of bleeding lesions of the skin, nasal and oral mucosa in patients with HHT. Methodology/Principal: We treated 16 HHT patients with intractable bleeding from telangiectasias using the 980-nm diode laser as an office procedure using local anesthesia. We recorded hemoglobin levels before and after treatment and used disability questionnaires. Results: All patients treated had an improvement in hemoglobin levels and disability scores. In patients with multiple lesions hemoglobin levels improved from a mean of 8.4 to 11.2 (p = 0.008). The disability index in this group improved from a mean of 5.3 to 2.8 (p = 0.007). Follow-up ranged between 4 and 12 months. Conclusions: The 980-nm diode laser is a good office based solution for bleeding in HHT.

关键词： HHT Laser Epistaxis Osler-Weber-Rendu

A NOVEL QUANTITATIVE ULTRASOUND TECHNIQUE IN THE MANAGEMENT OF OSTEOPOROSIS-A REFERENCE DATABASE COMPARISON

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A NOVEL QUANTITATIVE ULTRASOUND TECHNIQUE IN THE MANAGEMENT ...

Adjuvant chemotherapy after radical cystectomy:Do all patients who need chemotherapy after surgery actually receive it?

1st International Conference on Bone and Mineral Research

作者： Irit yaniv Sunlight Medical Ltd.

＜正＞Introduction: Osteoporosis is a fast growing medical problem,which is today becoming an *** to the definition of the World Health Organization,osteoporosis is the gradual decline of bone mass with age,leading to increased bone fragility and *** asymptomatic nature of osteoporosis causes severe limitations in diagnosing the disease in a timely and effective ***,the main objective for any medical diagnostic device is to provide a robust and accurate technology for aiding in testing,diagnosing and monitoring of patients

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