Sniffing Bacteria with a Carbon-Dot Artificial Nose

作     者：Nitzan Shauloff Ahiud Morag Karin Yaniv Seema Singh Ravit Malishev Ofra Paz-Tal Lior Rokach Raz Jelinek Nitzan Shauloff;Ahiud Morag;Karin Yaniv;Seema Singh;Ravit Malishev;Ofra Paz-Tal;Lior Rokach;Raz Jelinek

作者机构：Department of ChemistryBen Gurion University of the Negev84105 Beer ShevaIsrael Department of Biotechnology EngineeringBen Gurion University of the Negev84105 Beer ShevaIsrael Chemistry DepartmentNuclear Research CenterNegevP.O.Box 900184190 Beer ShevaIsrael Department of Software and Information System EngineeringBen-Gurion University of the NegevBeer ShevaIsrael Ilse Katz Institute for NanotechnologyBen Gurion University of the Negev84105 Beer ShevaIsrael 

出 版 物：《Nano-Micro Letters》 (纳微快报（英文版）)

年 卷 期：2021年第13卷第7期

页      面：138-152页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：We are grateful to Dr.Natalya Froumin(XPS) Dr.Yanna Milionshi(TGA) Dr.Jurgen Jopp(AFM) Dr.Igor Mokmanov for assistance with GC-MS experiments and Mrs.Galia Strinkovski for mentoring 

主　　题：Carbon dots Bacterial detection Bacterially emitted volatile molecules Capacitive gas sensors Gas polarity 

摘      要：Continuous,real-time monitoring and identification of bacteria through detection of microbially emitted volatile molecules are highly sought albeit elusive *** introduce an artificial nose for sensing and distinguishing vapor molecules,based upon recording the capacitance of interdigitated electrodes(IDEs)coated with carbon dots(C-dots)exhibiting different *** of the C-dot-IDEs to volatile molecules induced rapid capacitance changes that were intimately dependent upon the polarities of both gas molecules and the electrode-deposited *** deciphered the mechanism of capacitance transformations,specifically substitution of electrode-adsorbed water by gas molecules,with concomitant changes in capacitance related to both the polarity and dielectric constants of the vapor molecules *** C-dot-IDE gas sensor exhibited excellent selectivity,aided by application of machine learning *** capacitive C-dot-IDE sensor was employed to continuously monitor microbial proliferation,discriminating among bacteria through detection of distinctive“volatile compound fingerprintfor each bacterial *** C-dot-IDE platform is robust,reusable,readily assembled from inexpensive building blocks and constitutes a versatile and powerful vehicle for gas sensing in general,bacterial monitoring in particular.