检索结果-南通市图书馆

Characteristics of replication and pathogenicity of SARS-CoV-2 Alpha and Delta isolates

Virologica Sinica 2022年第6期37卷 804-812页

作者： Xiao-Li Feng Dandan Yu Mi Zhang Xiaohong Li Qing-Cui Zou Wentai Ma Jian-Bao Han Ling Xu Cuixian Yang Wang Qu Zhong-Hua Deng Junyi long yanghaopeng long Mingkun Li Yong-Gang Yao Xing-Qi Dong Jianxiong Zeng Ming-Hua Li Kunming National High-level Biosafety Research Center for Non-Human Primates Center for Biosafety Mega-ScienceKunming Institute of ZoologyChinese Academy of SciencesKunming650107China Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common DiseasesKunming Institute of ZoologyChinese Academy of SciencesKunming650201China National Resource Center for Non-Human Primates National Research Facility for Phenotypic&Genetic Analysis of Model Animals(Primate Facility)Kunming Institute of ZoologyChinese Academy of SciencesKunming650107China Department of Infectious Diseases Yunnan Provincial Infectious Diseases HospitalKunming650301China Key Laboratory of Genomic and Precision Medicine Beijing Institute of GenomicsChinese Academy of Sciencesand China National Center for BioinformationBeijing100101China University of Chinese Academy of Sciences Beijing100049China Center for Excellence in Animal Evolution and Genetics Chinese Academy of SciencesKunming650201China Kunming College of Life Science University of Chinese Academy of SciencesKunming650204China Yunnan Key Laboratory of Biodiversity Information Kunming Institute of ZoologyChinese Academy of SciencesKunming650201China

The continuously arising of SARS-CoV-2 variants has been posting a great threat to public health safety globally,from B.1.17(Alpha), B.1.351(Beta), P.1(Gamma), B.1.617.2(Delta) to B.1.1.529(Omicron). The emerging or reemerging of the SARS-CoV-2 variants of concern is calling for the constant monitoring of their epidemics,pathogenicity and immune escape. In this study, we aimed to characterize replication and pathogenicity of the Alpha and Delta variant strains isolated from patients infected in Laos. The amino acid mutations within the spike fragment of the isolates were determined via sequencing. The more efficient replication of the Alpha and Delta isolates was documented than the prototyped SARS-CoV-2 in Calu-3 and Caco-2 cells, while such features were not observed in Huh-7, Vero E6 and HPA-3 cells. We utilized both animal models of human ACE2(hACE2)transgenic mice and hamsters to evaluate the pathogenesis of the isolates. The Alpha and Delta can replicate well in multiple organs and cause moderate to severe lung pathology in these animals. In conclusion, the spike protein of the isolated Alpha and Delta variant strains was characterized, and the replication and pathogenicity of the strains in the cells and animal models were also evaluated.

关键词： SARS-CoV-2 Variants of concern(VOC) Alpha Delta hACE2 transgenic mice Hamster

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Infectivity of SARS-CoV-2 and protection against reinfection in rats

引用

Zoological Research 2022年第6期43卷 945-948页

作者： Dandan Yu yanghaopeng long Ling Xu Jian-Bao Han Jiawei Xi Jianlin Xu Lu-Xiu Yang Xiao-Li Feng Qing-Cui Zou Wang Qu Jiangwei Lin Ming-Hua Li Yong-Gang Yao Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common DiseasesKunming Institute of ZoologyChinese Academy of SciencesKunmingYunnan 650201China Kunming National High-Level Biosafety Research Center for Non-Human Primates Center for Biosafety Mega-ScienceKunming Institute of ZoologyChinese Academy of SciencesKunmingYunnan 650107China Kunming College of Life Science University of Chinese Academy of SciencesKunmingYunnan 650204China

DEAR EDITOR,The severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) pandemic remains an important global public health issue. In this study, we unexpectedly found that wildtype Sprague-Dawley(SD) rats can be infected with the SARS-CoV-2 prototype. Our results showed direct experimental evidence of the infectivity of SARS-CoV-2 infection, subsequent pathogenicity, and protection against reinfection in rats.

关键词： infection rats acute

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Ultrathin surface coating of Cu enabling long-life Zn metal anodes

引用

Rare Metals 2024年第5期43卷 2125-2135页

作者： Sang-Sang Liu Ya-Ru Liang Wen-long Chen Ze-Hua Wang Yi-long Dai Fu-Gang Qi Zeng-Sheng Ma Xiao-Ping Ouyang School of Materials Science and Engineering Xiangtan UniversityXiangtan 411105China Key Laboratory of Low Dimensional Materials and Application Technology of Ministry of Education Xiangtan UniversityXiangtan 411105China

Aqueous zinc-ion batteries(AZIBs)are regarded as promising energy storage devices due to their low cost,high capacity,and ecological ***,the severe dendritic growth and side reactions hinder their practical applicability ***,an ultrathin Cu coating layer(~200 nm)is decorated on zinc foils via filtered cathodic vacuum arc deposition technology,aiming to achieve high-performance *** Cu layer effectively suppresses chemical corrosion and hydrogen evolution reactions and enables preferential(002)Zn deposition during the stripping/plating ***,the Cu@Zn anode represents an elongated cycle life over 4,000 h at 2 mA·cm^(-2)/2 mAh·cm^(-2).Even in conditions of high current density of 5 and 10 mA·cm^(-2),the Cu@Zn anode shows prolonged cycling stability exceeding 4000 and 2000 h,*** advantages also bring high Coulombic efficiency of 99.87%under 5 mAh·cm^(-2)in Cu@Ti||Zn half-cell over 1500 ***,the Cu@Zn||MnO_(2)full cell demonstrates a superior cyclability with a specific capacity of 203 mAh·g^(-1)after 500 cycles a1 A·g^(-1).

关键词： Zn ion battery Zn metal anode Zn(002)plane Cu coating

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Photocatalytic activation of sulfite by N-doped porous biochar/MnFe_(2)O_(4) interface-driven catalyst for efficient degradation of tetracycline

引用

Green Energy & Environment 2024年第3期9卷 481-494页

作者： long Cheng Yuanhui Ji Jiangsu Province Hi-Tech Key Laboratory for Biomedical Research School of Chemistry and Chemical EngineeringSoutheast UniversityNanjing211189China

A novel photo-catalytic system composed of N-doped biochars(NBCs),MnFe_(2)O_(4) and sulfite activation under ultraviolet(NBCs/MnFe_(2)O_(4)/sulfite/UV)was constructed to realize the efficient eliminate of tetracycline(TC).As the carrier of MnFe_(2)O_(4),NBCs were synthesized from alfalfa,which has large specific surface area,graphite like structure and hierarchical porous *** adsorption isotherm indicated that NBCs/MnFe_(2)O_(4)-2:1 had the best adsorption performance for TC(347.56 mg g^(-1)).Through synergistic adsorption and photocatalysis,the removal rate of TC reached 84%,which was significantly higher than that of MnFe_(2)O_(4).Electrochemical impedance spectroscopy(EIS)and Photoluminescence(PL)characterization results showed that the introduction of NBCs improved the separation efficiency of photogenerated electron and hole pairs and enhanced the photocatalytic ***,the adsorption,degradation mechanism and degradation path of TC by the catalyst were systematically analyzed by coupling HPLC–MS measurement with the theoretical *** the advantages of excellent degradation performance,low cost,easy separation and environmental friendliness of NBCs/MnFe_(2)O_(4),this work was expected to provide a new path for the practical application of biochar.

关键词： Biochar MnFe_(2)O_(4) Sulfite Adsorption Photocatalysis

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Prediction model for corrosion rate of low-alloy steels under atmospheric conditions using machine learning algorithms

引用

International Journal of Minerals,Metallurgy and Materials 2024年第2期31卷 337-350页

作者： Jingou Kuang Zhilin long School of Civil Engineering Xiangtan UniversityXiangtan 411105China

This work constructed a machine learning(ML)model to predict the atmospheric corrosion rate of low-alloy steels(LAS).The material properties of LAS,environmental factors,and exposure time were used as the input,while the corrosion rate as the output.6 dif-ferent ML algorithms were used to construct the proposed *** optimization and filtering,the eXtreme gradient boosting(XG-Boost)model exhibited good corrosion rate prediction *** features of material properties were then transformed into atomic and physical features using the proposed property transformation approach,and the dominant descriptors that affected the corrosion rate were filtered using the recursive feature elimination(RFE)as well as XGBoost *** established ML models exhibited better predic-tion performance and generalization ability via property transformation *** addition,the SHapley additive exPlanations(SHAP)method was applied to analyze the relationship between the descriptors and corrosion *** results showed that the property transformation model could effectively help with analyzing the corrosion behavior,thereby significantly improving the generalization ability of corrosion rate prediction models.

关键词： machine learning low-alloy steel atmospheric corrosion prediction corrosion rate feature fusion

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Frequency Domain Fatigue Evaluation on SCR Girth-Weld Based on Structural Stress

引用

China Ocean Engineering 2024年第2期38卷 255-270页

作者： ZHANG long ZHAO Tian-feng College of Safety and Ocean Engineering China University of Petroleum(Beijing)Beijing 102249China

The Steel Catenary Riser(SCR)is a vital component for transporting oil and gas from the seabed to the floating *** harsh environmental conditions and complex platform motion make the SCR’s girth-weld prone to fatigue *** structural stress fatigue theory and Master S-N curve method provide accurate predictions for the fatigue damage on the welded joints,which demonstrate significant potential and compatibility in multi-axial and random fatigue ***,we propose a new frequency fatigue model subjected to welded joints of SCR under multiaxial stress,which fully integrates the mesh-insensitive structural stress and frequency domain random process and transforms the conventional welding fatigue technique of SCR into a spectrum analysis technique utilizing structural ***,a full-scale FE model of SCR with welds is established to obtain the modal structural stress of the girth weld and the frequency response function(FRF)of modal coordinate,and a biaxial fatigue evaluation about the girth weld of the SCR can be achieved by taking the effects of multi-load correlation and pipe-soil interaction into *** research results indicate that the frequency-domain fatigue results are aligned with the time-domain results,meeting the fatigue evaluation requirements of the SCR.

关键词： SCR girth weld random vibration self(cross)power spectrum structural stress method biaxial fatigue damage

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

long-lived lunar volcanism sustained by precession-driven core-mantle friction

引用

National Science Review 2024年第2期11卷 114-123页

作者： Shuoran Yu Xiao Xiao Shengxia Gong Nicola Tosi Jun Huang Doris Breuer long Xiao Dongdong Ni State Key Laboratory of Lunar and Planetary Sciences Macau University of Science and Technology Planetary Science Institute State Key Laboratory of Geological Processes and Mineral Resources School of Earth Sciences China University of Geosciences CAS Key Laboratory of Planetary Sciences Shanghai Astronomical Observatory Institute of Planetary Research German Aerospace Centre(DLR)

Core-mantle friction induced by the precession of the Moon's spin axis is a strong heat source in the deep lunar mantle during the early phase of a satellite's evolution, but its influence on the long-term thermal evolution still remains poorly explored. Using a one-dimensional thermal evolution model, we show that core-mantle friction can sustain global-scale partial melting in the upper lunar mantle until ～3.1 Ga, thus accounting for the intense volcanic activity on the Moon before ～3.0 Ga. Besides, core-mantle friction tends to suppress the secular cooling of the lunar core and is unlikely to be an energy source for the long-lived lunar core dynamo. Our model also favours the transition of the Cassini state before the end of the lunar magma ocean phase(～4.2 Ga), which implies a decreasing lunar obliquity over time after the solidification of the lunar magma ocean. Such a trend of lunar obliquity evolution may allow volcanically released water to be buried in the lunar regolith of the polar regions. As a consequence, local water ice could be more abundant than previously thought when considering only its accumulation caused by solar wind and comet spreading.

关键词： Moon precession orbit volcanism

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Designing Proportional-Integral Consensus Protocols for Second-Order Multi-Agent Systems Using Delayed and Memorized State Information

引用

IEEE/CAA Journal of Automatica Sinica 2024年第4期11卷 878-892页

作者： Honghai Wang Qing-long Han the College of Information Science and Engineering State Key Laboratory of Synthetical Automation for Process IndustriesNortheastern UniversityShenyang 110819China the School of Science Computing and Engineering TechnologiesSwinburne University of TechnologyMelbourneVIC 3122Australia

This paper is concerned with consensus of a secondorder linear time-invariant multi-agent system in the situation that there exists a communication delay among the agents in the network.A proportional-integral consensus protocol is designed by using delayed and memorized state *** the proportional-integral consensus protocol,the consensus problem of the multi-agent system is transformed into the problem of asymptotic stability of the corresponding linear time-invariant time-delay *** that the location of the eigenvalues of the corresponding characteristic function of the linear time-invariant time-delay system not only determines the stability of the system,but also plays a critical role in the dynamic performance of the *** this paper,based on recent results on the distribution of roots of quasi-polynomials,several necessary conditions for Hurwitz stability for a class of quasi-polynomials are first *** allowable regions of consensus protocol parameters are *** necessary and sufficient conditions for determining effective protocol parameters are *** designed protocol can achieve consensus and improve the dynamic performance of the second-order multi-agent ***,the effects of delays on consensus of systems of harmonic oscillators/double integrators under proportional-integral consensus protocols are ***,some results on proportional-integral consensus are derived for a class of high-order linear time-invariant multi-agent systems.

关键词： Consensus protocol Hurwitz stability multi-agent systems quasi-polynomials time delay

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Automatic modeling algorithm of stochastic error for inertial sensors

引用

Control Theory and Technology 2024年第1期22卷 81-91页

作者： Luodi Zhao long Zhao School of Automation Science and Electrical Engineering Beihang UniversityBeijing100191China Digital Navigation Center Beihang UniversityBeijing100191China Science and Technology on Aircraft Control Laboratory Beihang UniversityBeijing100191China

This paper proposes an automatic algorithm to determine the properties of stochastic processes and their parameters for inertial error. The proposed approach is based on a recently developed method called the generalized method of wavelet moments (GMWM), whose estimator was proven to be consistent and asymptotically normally distributed. This algorithm is suitable mainly (but not only) for the combination of several stochastic processes, where the model identification and parameter estimation are quite difficult for the traditional methods, such as the Allan variance and the power spectral density analysis. This algorithm further explores the complete stochastic error models and the candidate model ranking criterion to realize automatic model identification and determination. The best model is selected by making the trade-off between the model accuracy and the model complexity. The validation of this approach is verified by practical examples of model selection for MEMS-IMUs (micro-electro-mechanical system inertial measurement units) in varying dynamic conditions.

关键词： GMWM Stochastic process Inertial sensor Sensor calibration Error model Allan variance

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

CRD-CGAN:category-consistent and relativistic constraints for diverse text-to-image generation

引用

Frontiers of Computer Science 2024年第1期18卷 61-75页

作者： Tao HU Chengjiang long Chunxia XIAO College of Intelligent Systems Science and Engineering Hubei Minzu UniversityEnshi 445000China School of Computer Science Wuhan UniversityWuhan 430072China Key Laboratory of Performing Art Equipment&System Technology Ministry of Culture and TourismBeijing 100007China Meta Reality Labs BurlingameCA94010USA

Generating photo-realistic images from a text description is a challenging problem in computer *** works have shown promising performance to generate synthetic images conditional on text by Generative Adversarial Networks(GANs).In this paper,we focus on the category-consistent and relativistic diverse constraints to optimize the diversity of synthetic *** on those constraints,a category-consistent and relativistic diverse conditional GAN(CRD-CGAN)is proposed to synthesize K photo-realistic images *** use the attention loss and diversity loss to improve the sensitivity of the GAN to word attention and ***,we employ the relativistic conditional loss to estimate the probability of relatively real or fake for synthetic images,which can improve the performance of basic conditional ***,we introduce a category-consistent loss to alleviate the over-category issues between K synthetic *** evaluate our approach using the Caltech-UCSD Birds-200-2011,Oxford 102 flower and MS COCO 2014 datasets,and the extensive experiments demonstrate superiority of the proposed method in comparison with state-of-the-art methods in terms of photorealistic and diversity of the generated synthetic images.

关键词： text-to-image diverse conditional GAN relativi-stic category-consistent

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：