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GametesOmics:A Comprehensive Multi-omics Database for Exploring the Gametogenesis in Humans and Mice

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Genomics, Proteomics & Bioinformatics 2024年第1期22卷 121-130页

作者： Jianting An Jing Wang Siming Kong Shi Song Wei Chen Peng Yuan Qilong He yidong Chen Ye Li Yi yang Wei Wang Rong Li Liying Yan Zhiqiang Yan Jie Qiao State Key Laboratory of Female Fertility Promotion Center for Reproductive MedicineDepartment of Obstetrics and GynecologyPeking University Third HospitalBeijing 100191China National Clinical Research Center for Obstetrics and Gynecology Peking University Third HospitalBeijing 100191China Key Laboratory of Assisted Reproduction Ministry of EducationPeking UniversityBeijing 100191China Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology Beijing 100191China Peking-Tsinghua Center for Life Sciences Peking UniversityBeijing 100871China Beijing Advanced Innovation Center for Genomics Beijing 100191China

Gametogenesis plays an important role in the reproduction and evolution of *** transcriptomic and epigenetic alterations in this process can influence the reproductive capacity,fertilization,and embryonic *** rapidly increasing single-cell studies have provided valuable multi-omics ***,data from different layers and sequencing platforms have not been uniformed and integrated,which greatly limits their use for exploring the molecular mechanisms that underlie oogenesis and ***,we develop GametesOmics,a comprehensive database that integrates the data of gene expression,DNA methylation,and chromatin accessibility during oogenesis and spermatogenesis in humans and *** provides a user-friendly website and various tools,including Search and Advanced Search for querying the expression and epigenetic modification(s)of each gene;Tools with Differentially expressed gene(DEG)analysis for identifying DEGs,Correlation analysis for demonstrating the genetic and epigenetic changes,Visualization for displaying single-cell clusters and screening marker genes as well as master transcription factors(TFs),and MethylView for studying the genomic distribution of epigenetic *** also provides Genome Browser and Ortholog for tracking and comparing gene expression,DNA methylation,and chromatin accessibility between humans and *** offers a comprehensive resource for biologists and clinicians to decipher the cell fate transition in germ cell development,and can be accessed at http://***/.

关键词： Gametogenesis Oogenesis Spermatogenesis Transcriptomics Epigenomics

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建窑建盏与宋代武夷茶文化

中国陶瓷 2008年第10期44卷 75-77页

作者：杨义东刘芳景德镇陶瓷学院景德镇333000 武夷山陶瓷艺术研究所武夷山354300 号德镇陶瓷学院科技艺术学院景德镇333000

建盏在宋代茶文化史上扮演着重要的角色,而与其同一产地的建茶(武夷茶)也同样备受瞩目。文章通过介绍建盏与武夷茶文化之间的渊源关系,深入阐述了武夷茶对建盏的影响,以及武夷茶文化在整个宋代茶文化历史中的重要地位。

关键词：建盏武夷茶茶具

基于多元回归分析的中国出口贸易额与环境污染的模型建立

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生态经济 2015年第6期31卷 46-48页

作者：陈燕杨义东云南师范大学商学院云南昆明650000 云南大学滇池学院云南昆明650000

中国作为世界贸易大国,对外贸易的开展对中国经济的增长起到了显著作用.但随着贸易的推进,生态环境问题也越来越受到关注,贸易的扩张和生态环境的污染矛盾进一步激化.文章运用2005～2013年的最新数据对中国出口贸易额和全国环境主要污... 详细信息

中国作为世界贸易大国,对外贸易的开展对中国经济的增长起到了显著作用.但随着贸易的推进,生态环境问题也越来越受到关注,贸易的扩张和生态环境的污染矛盾进一步激化.文章运用2005～2013年的最新数据对中国出口贸易额和全国环境主要污染物的相关性进行分析,利用SPSS统计学软件中的相关分析和回归分析建立数学模型,得出结论中国贸易出口额与环境主要污染物：化学需氧量、氨氮、氮氧化物呈现显著正相关性,与二氧化硫呈负相关,并拟合出它们之间的数学模型.

关键词：出口贸易额相关分析多元回归分析环境污染数学模型

Tailored ionically conductive graphene oxide-encased metal ions for ultrasensitive cadaverine sensor

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Chinese Chemical Letters 2024年第8期35卷 508-513页

作者： Ying Chen Li Li Junyao Zhang Tongrui Sun Xuan Zhang Shiqi Zhang Jia Huang yidong Zou School of Materials Science and Engineering Tongji UniversityShanghai 201804China Shanghai Key Laboratory of Anesthesiology and Brain Functional Modulation Translational Research Institute of Brain and Brain-Like IntelligenceShanghai Fourth People’s Hospital Affiliated to Tongji UniversityTongji UniversityShanghai 200434China School of Mechanical Engineering Nantong UniversityNantong 226019China

Intelligent chemical sensors have been extensively used in food safety and environmental assessment,while limited sensitivity and homogeneity bring about huge obstacles to their practical ***,novel ionically conductive sensitive materials were elaborately designed based on metal ion decorated graphene oxide(GO)via a facile and general in-situ spin-coating strategy,where the abundant functional groups(-OH and-COOH)of GO layer could provide natural binding sites for various bivalent metal cations(such as Cu^(2+),Ni^(2+),Zn^(2+),Co^(2+),and Mg^(2+))through coordination and electrostatic *** intercalated metal cations on the layered GO nanosheets can be regarded as charge carriers and complexation with targeted gas(cadaverine,Cad),which is a typical metabolites production and food *** contrast,the designed GO@Cu(Ⅱ)sensor exhibited the optimal sensing performance toward Cad molecules at room temperature,including ultra-low detection limit(ca.3 nL),excellent sensitivity,and rapid low concentration detection rate(only 16 s).Interestingly,the sensor exhibited an irreversible and specific response toward Cad,while it showed a transient and reversible response to other interfering gases,implying its outstanding *** addition,the GO@Cu(Ⅱ)sensor enabled real-time monitoring of the decay progression of cheese,and it exhibited great potential for large-scale production via its excellent *** provides an efficient approach to tailoring intelligent chemical sensors for real-time food safety monitoring and human health warning.

关键词： Graphene oxide Cadaverine monitoring Chemical sensor Ionically conductive Homogeneity

基于网格和密度的海量数据增量式离群点挖掘算法

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计算机研究与发展 2011年第5期48卷 823-830页

作者：张净孙志挥杨明倪巍伟杨宜东东南大学计算机科学与工程系南京210096 江苏大学电气信息工程学院江苏镇江212001 南京师范大学计算机科学与技术学院南京210097

处理海量和高维数据已经成为设计离群点算法面临的重要任务和挑战,针对海量数据的特点提出一种基于网格和密度的增量式离群点挖掘算法IGDLOF,算法的基本思想为:采用网格的七元组信息减少数据维数和数量,利用增量更新减少内存需求.通过... 详细信息

处理海量和高维数据已经成为设计离群点算法面临的重要任务和挑战,针对海量数据的特点提出一种基于网格和密度的增量式离群点挖掘算法IGDLOF,算法的基本思想为:采用网格的七元组信息减少数据维数和数量,利用增量更新减少内存需求.通过代表点过滤相应的主体数据,先判断再进行近似密度计算的方法减少计算量,降低算法的复杂度.通过在真实和仿真数据集的测试表明,IGDLOF增量算法可与LOF算法保持相同的精确度,而执行效率得到显著的提高.

关键词：海量数据网格密度离群点挖掘增量 LOF算法

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综合性湿地规划研究——以杭州江海湿地为例

城市规划 2015年第A1期39卷 78-85页

作者：杨毅栋郭崇文李健杭州市城市规划设计研究院

湿地建设对于提高城市空间健康品质意义非凡。杭州江海湿地位于杭州大江东新城的东北两侧。1980年代以来大范围的围海、填海活动严重破坏了当地的自然环境,造成重要的海洋经济生物繁衍场所消失,许多珍稀物种濒临灭绝,对于此区域的生态... 详细信息

湿地建设对于提高城市空间健康品质意义非凡。杭州江海湿地位于杭州大江东新城的东北两侧。1980年代以来大范围的围海、填海活动严重破坏了当地的自然环境,造成重要的海洋经济生物繁衍场所消失,许多珍稀物种濒临灭绝,对于此区域的生态修复工作迫在眉睫。而该地区多样的生境类型使得其营造为集观光、农渔业生产、科教、自然环境保护等功能于一体的综合性生态湿地成为可能,以此为大江东新城提供生态屏障,提升大江东新城空间品质。

关键词：江海湿地湿地分类综合性湿地景观湿地水文

Thermally Conductive and UV-EMI Shielding Electronic Textiles for Unrestricted and Multifaceted Health Monitoring

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Nano-Micro Letters 2024年第10期16卷 149-162页

作者： yidong Peng Jiancheng Dong Jiayan Long Yuxi Zhang Xinwei Tang Xi Lin Haoran Liu Tuoqi Liu Wei Fan Tianxi Liu Yunpeng Huang Key Laboratory of Synthetic and Biological Colloids Ministry of EducationSchool of Chemical and Material EngineeringJiangnan UniversityWuxi 214122People's Republic of China

Skin-attachable electronics have garnered considerable research attention in health monitoring and artificial intelligence domains,whereas susceptibility to elec-tromagnetic interference(EMI),heat accumulation issues,and ultraviolet(UV)-induced aging problems pose significant constraints on their potential ***,an ultra-elas-tic,highly breathable,and thermal-comfortable epidermal sensor with exceptional UV-EMI shielding performance and remarkable thermal conductivity is developed for high-fidelity monitoring of multiple human electrophysiological *** filling the elastomeric microfibers with thermally conductive boron nitride nanoparticles and bridging the insulating fiber interfaces by plating Ag nanoparticles(NPs),an interwoven thermal con-ducting fiber network(0.72 W m^(-1) K^(-1))is constructed benefiting from the seamless thermal interfaces,facilitating unimpeded heat dissipation for comfort skin *** excitingly,the elastomeric fiber substrates simultaneously achieve outstanding UV protection(UPF=143.1)and EMI shielding(SET>65,X-band)capabilities owing to the high electrical conductivity and surface plasmon resonance of Ag ***,an electronic textile prepared by printing liquid metal on the UV-EMI shielding and thermally conductive nonwoven textile is finally utilized as an advanced epidermal sensor,which succeeds in monitoring different electrophysiological signals under vigorous electromagnetic *** research paves the way for developing protective and environmentally adaptive epidermal electronics for next-generation health regulation.

关键词： Skin electronics Thermal regulating textiles Electromagnetic interference shielding Ultraviolet proof Health monitoring

走进·走在·走出——象山丹城基督教堂设计过程回顾及感悟

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建筑学报 2010年第7期 56-59页

作者：莫洲瑾杨易栋浙江大学建筑设计研究院杭州310027

2009年末,中国建筑学会评选出了300个＂建国60周年建筑创作大奖＂,象山丹城基督教堂赫然在列。这是一个小项目,一共不到6300m^2,并且位于一个地处大海边缘,人口不过50万的偏僻小县城,＂小＂得有点微不足道,

关键词：基督教堂设计过程山丹中国建筑学会建筑创作海边

Observation of the failure mechanism in Ag_(10)Ge_(15)Te_(75)-based memristor induced by ion transport

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Nano Research 2024年第9期17卷 8431-8437页

作者： Yuwei Xiong Kuibo Yin Weiwei Sun Jingcang Li Shangyang Shang Lei Xin Qiyun Wu Xiaoran Gong yidong Xia Litao Sun SEU-FEI Nano-Pico Center Key Laboratory of MEMS of Ministry of EducationSoutheast UniversityNanjing 210096China College of Engineering and Applied Sciences Nanjing UniversityNanjing 210093China

The solid-electrolyte-based memristors have attracted tremendous attention for the next-generation nonvolatile memory for both logic and neuromorphic ***,they encounter variability performance challenges which originated from the random ionic transport and conductive filaments ***,the electrochemical metallized mechanism associated with ion transport has been ***,the failure mechanism caused by ion transport during cycles is rarely ***,the five stages of failure in the Ag/Ag_(10)Ge_(15)Te_(75)/W memristor are elucidated through ex-situ current-voltage measurements combined with in-situ transmission electron microscopy *** investigation reveals that the migration and enrichment of Ag ions result in the precipitation of Ag_(2)*** formation of Ag_(2)Te hinders the device's ability to maintain its bipolar characteristics and also decreases the resistance value of the high resistance state,thereby reducing the device's switching *** promising results provide important guidance for the future design of structures and the manipulation of ion transport for high-performance memristors.

关键词： Ag10Ge15Te75 in-situ transmission electron microscopy(TEM) failure mechanism