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China Geology 2024年第2期7卷 248-263页

作者： chang yang Yong-bo Tie Xian-zheng Zhang Yan-feng Zhang Zhi-jie Ning Zong-liang Li Chinese Academy of Geological Sciences Beijing 100037China Chengdu Center of China Geological Survey China Geological SurveyChengdu 610081China Technology innovation center for risk prevention and mitigation of geohazard Ministry of Natural ResourcesChengdu 611734China Observation and Research Station of Chengdu Geological Hazards Ministry of Natural ResourcesChengdu 610000China

Xinqiao Gully is located in the area of the 2008 Wenchuan M_(s)8.0 earthquake in Sichuan province,*** on the investigation of the 2023"6-26"Xinqiao Gully debris flow event,this study assessed the effectiveness of the debris flow control project and evaluated the debris flow *** field investigation and numerical simulation methods,the indicators of flow intensity reduction rate and storage capacity fullness were proposed to quantify the effectiveness of the engineering measures in the debris flow *** simulation results show that the debris flow control project reduced the flow intensity by41.05%to 64.61%.The storage capacity of the dam decreases gradually from upstream to the mouth of the gully,thus effectively intercepting and controlling the debris *** evaluating the debris flow of different recurrence intervals,further measures are recommended for managing debris flow events.

关键词： Landslide Debris flow Hazard assessment Numerical simulation OpenLISEM Prevention and control project Wenchuan M_(s)8.0 earthquake Xinqiao Gully Sichuan province Geological hazards survey engineering

计及可变流量调节模式的电热综合能源系统条件分布鲁棒优化调度

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中国电机工程学报 2024年第12期44卷 4702-4714,I0009页

作者：杨畅李正烁山东大学电气工程学院山东省济南市250061

电-热综合能源系统(integrated electricity and heat system,IEHS)可以有效促进可再生能源消纳。构建区域供热系统精细化模型与合理的可再生能源不确定性出力模型是调度IEHS的两个难点。该文首先提出计及可变流量调节模式的IEHS条件分... 详细信息

电-热综合能源系统(integrated electricity and heat system,IEHS)可以有效促进可再生能源消纳。构建区域供热系统精细化模型与合理的可再生能源不确定性出力模型是调度IEHS的两个难点。该文首先提出计及可变流量调节模式的IEHS条件分布鲁棒优化调度模型,主要有两点改进:通过构建基于修正模糊集的条件分布鲁棒模型建模可再生能源预测误差与其预测出力信息之间的内在依赖性,提升调度结果安全性与最优性;基于流体能量守恒方程与一阶隐式迎风格式建立可变流量调节模式下的IEHS调度模型,以期充分挖掘区域供热系统的灵活性,促进可再生能源消纳。所构建的IEHS调度模型为含有大量非线性约束的条件分布鲁棒模型,难以直接求解。对此,通过对偶理论与条件风险价值近似方法将条件分布鲁棒模型转化为含非线性约束的确定性模型,并提出自适应McCormick算法用以求解非线性约束。通过不同规模案例仿真表明,所提模型能够降低IEHS的调度成本,所提算法在保证可行性的条件下快速求出问题的近似最优解,最优间隙小于千分之一。

关键词：电-热综合能源系统分布鲁棒优化可变流量调节模式 McCormick松弛联合机会约束

General anesthetic agents induce neurotoxicity through oligodendrocytes in the developing brain

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Zoological Research 2024年第3期45卷 691-703页

作者： Wen-Xin Hang Yan-chang yang Yu-Han Hu Fu-Quan Fang Lang Wang Xing-Hua Qian Patrick M.McQuillan Hui Xiong Jian-Hang Leng Zhi-Yong Hu Department of Anesthesiology First Affiliated HospitalZhejiang University School of MedicineHangzhouZhejiang 310003China Department of Cell Biology Yale UniversityNew HavenCT 06520USA Department of Neurology of the First Affiliated Hospital Interdisciplinary Institute of Neuroscience and TechnologySchool of Brain Science and Brain MedicineZhejiang University School of MedicineHangzhouZhejiang 310027China Department of Anesthesiology Jiaxing Maternity and Childcare Health HospitalJiaxingZhejiang 314009China Department of Anesthesiology Penn State Hershey Medical CentrePenn State College of MedicineHersheyPA 17033USA Department of Central Laboratory Affiliated Hangzhou First People’s HospitalWestlake University School of MedicineHangzhouZhejiang 310006China

General anesthetic agents can impact brain function through interactions with neurons and their effects on glial *** perform essential roles in the central nervous system,including myelin sheath formation,axonal metabolism,and neuroplasticity *** are particularly vulnerable to the effects of general anesthetic agents resulting in impaired proliferation,differentiation,and *** are increasingly interested in the effects of general anesthetic agents on *** agents not only act on the surface receptors of oligodendrocytes to elicit neuroinflammation through modulation of signaling pathways,but also disrupt metabolic processes and alter the expression of genes involved in oligodendrocyte development and *** this review,we summarize the effects of general anesthetic agents on *** anticipate that future research will continue to explore these effects and develop strategies to decrease the incidence of adverse reactions associated with the use of general anesthetic agents.

关键词： Oligodendrocytes General anesthetic agents Neurotoxicity Central nervous system Perioperative neurocognitive disorders

如何理解现代个体的人权——再思哈贝马斯的双重批判与主体间性重构

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人权 2024年第2期 148-164页

作者：杨畅中南大学人文学院哲学系

人权不仅是展现个体与共同体关系的要点,也是面向现实的政治哲学关注的焦点。人权与个体的自我认同密不可分,而自由主义与社群主义之争却揭示了,对个体的理解一直存在着实践性与历史性之间的矛盾。为了调和这种矛盾,哈贝马斯从德国古典... 详细信息

人权不仅是展现个体与共同体关系的要点,也是面向现实的政治哲学关注的焦点。人权与个体的自我认同密不可分,而自由主义与社群主义之争却揭示了,对个体的理解一直存在着实践性与历史性之间的矛盾。为了调和这种矛盾,哈贝马斯从德国古典哲学出发,分别对实践性和历史性作出了考察:费希特把对象性思维融贯在了自我认同中,他揭示出了个体的实践性,却忽略了个体的现实要素;黑格尔在同一性思维下阐释了自我认同,他从历史性维度考察了个体,却让理性法则统治了现实。最终,哈贝马斯通过批判主体性哲学的桎梏,从交往理论重构了现代个体自我认同的过程,他不仅调和了自我认同中实践性与历史性的分歧,也阐释了人权蕴含着的主体间性内核。

关键词：人权自我认同实践性历史性主体间性

Understanding the Human Rights of Modern Individuals—Revisiting Habermas’s Dual Critique and the Reconstruction of Intersubjectivity

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The Journal of Human Rights 2024年第2期23卷 420-475页

作者：杨畅 PAN Yingzhao(Translated) Department of Philosophy School of HumanitiesCentral South University 不详

Human rights are not only pivotal in depicting the relationship between individuals and communities but also a focal point of political philosophical concerns oriented towards reality. The inseparability of human rights from individual self-identity reveals a contradiction between practicality and historicity in understanding individuals, as highlighted in the debate between liberalism and communitarianism. In order to reconcile this contradiction, Habermas,drawing from German classical philosophy, examines practicality and historicity separately: while Fichte intertwines objectivity in self-identity, revealing the practicality of individuals but neglecting their real elements, Hegel interprets self-identity under the concept of unity,examining individuals from a historical dimension but letting rational rules dominate reality. Ultimately, Habermas reconstructs the process of modern individual self-identity from the theory of communicative action by critiquing the shackles of subjective philosophy. He not only reconciles the divergence between practicality and historicity in self-identity, but also elucidates the intersubjective core inherent in human rights.

关键词： human rights self-identity practicality historicity intersubjectivity

Research on takeout distribution based on combination mode of order dispatching and grabbing

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Kongzhi yu Juece/Control and Decision 2024年第9期39卷 3135-3142页

作者： Feng, Ai-Lan Zhou, Ying-Xue Gong, Yan-Ru yang, Le-chang School of Mechanical Engineering University of Science and Technology Beijing Beijing 100083 China Mechanical Development Technology Co.，Ltd China General Academy of Mechanical Sciences Group Beijing 100044 China Department of Intelligent Manufacturing Tianjin College of University of Science and Technology Beijing Tianjin 301830 China

The takeout platform continues to improve the quality of customer services and reduce costs while ignoring the interests of riders. Considering the dilemma of riders, the incentive mechanism of reward and punishment is introduced, and the takeout order allocation model is established with the platform cost, customer satisfaction and rider incentive income as the objective. Based on the order allocation mode of combination of dispatching and grabbing, considering the convenience, distance and capability, the utility function is constructed to describe the preference and matching degree when grabbing order autonomously, and the Logit discrete selection model is used to simulate order grabbing behavior. The adaptive variable neighborhood search algorithm is designed to implement the platform dispatch allocation and path optimization. The experimental results show that the delivery scheme based on the order allocation mode of order-dispatching and grabbing effectively reduces the overall distribution cost, improve customer satisfaction and rider revenue compared with the mode of order-dispatching. The research results extend the theoretical research on the takeout order allocation mode, and provide reference for the benign development of takeout industry. © 2024 Northeast University. All rights reserved.

关键词： Customer satisfaction

Comprehensive analysis of the protein phosphatase 2A regulatory subunit B56ε in pan-cancer and its role and mechanism in hepatocellular carcinoma

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World Journal of Gastrointestinal Oncology 2024年第2期16卷 475-492页

作者： Hong-Mei Wu Yuan-Yuan Huang Yu-Qiu Xu Wei-Lai Xiang chang yang Ru-Yuan Liu Di Li Xue-Feng Guo Zheng-Bao Zhang Chun-Hua Bei Sheng-Kui Tan Xiao-Nian Zhu Guangxi Key Laboratory of Environmental Exposomics and Entire Lifecycle Health Guilin Medical UniversityGuilin 541199Guangxi Zhuang Autonomous RegionChina

BACKGROUND B56εis a regulatory subunit of the serine/threonine protein phosphatase 2A,which is abnormally expressed in tumors and regulates various tumor cell *** present,the application of B56εin pan-cancer lacks a comprehensive analysis,and its role and mechanism in hepatocellular carcinoma(HCC)are still *** Cancer Genome Atlas,Genotype-Tissue Expression,Gene Expression Profiling Interactive Analysis,and Tumor Immune Estimation Resource databases were used to analyze B56εexpression,prognostic mutations,somatic copy number alterations,and tumor immune characteristics in 33 *** relationships between B56εexpression levels and drug sensitivity,immuno-therapy,immune checkpoints,and human leukocyte antigen(HLA)-related genes were further *** Set Enrichment Analysis(GSEA)was performed to reveal the role of B56εin *** Cell Counting Kit-8,plate cloning,wound healing,and transwell assays were conducted to assess the effects of B56εinterference on the malignant behavior of HCC *** In most tumors,B56εexpression was upregulated,and high B56εexpression was a risk factor for adrenocortical cancer,HCC,pancreatic adenocarcinoma,and pheochromocytoma and paraganglioma(all P<0.05).B56εexpression levels were correlated with a variety of immune cells,such as T helper 17 cells,B cells,and *** was a positive correlation between B56εexpression levels with immune checkpoint genes and HLA-related genes(all P<0.05).The expression of B56εwas negatively correlated with the sensitivity of most chemotherapy drugs,but a small number showed a positive correlation(all P<0.05).GSEA analysis showed that B56εexpression was related to the cancer pathway,p53 downstream pathway,and interleukin-mediated signaling in *** of B56εexpression in HCC cells inhibited the proliferation,migration,and invasion capacity of tumor *** Tip:The expression of protein phosphatase 2A(PP2A)subunit B56εis up-regulated in most tumors,and its high

关键词： B56ε Prognosis Tumor microenvironment Immune infiltration Immunotherapy Hepatocellular carcinoma

基于改进MFAC的交直流微电网分布式二次控制

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中国电机工程学报 2024年第1期44卷 34-45,I0003页

作者：杨畅郑涛李鹏宇卜鸣西安交通大学电气工程学院陕西省西安市710049

针对现有交直流微电网分布式二次控制(distributed secondarycontrol,DSC)受分布式电源一次控制参数影响较大、通信拓扑结构复杂、二次控制参数难以整定等问题,提出基于改进MFAC的交直流微电网DSC(MFAC-DSC),利用分布式电源的历史采样... 详细信息

针对现有交直流微电网分布式二次控制(distributed secondarycontrol,DSC)受分布式电源一次控制参数影响较大、通信拓扑结构复杂、二次控制参数难以整定等问题,提出基于改进MFAC的交直流微电网DSC(MFAC-DSC),利用分布式电源的历史采样数据在线估计其动态线性化参数,解决了传统方法受一次控制参数影响较大的问题;通过优化DSC的通信结构和控制策略,避免了互联变流器参与二次控制通信,解决了互联变流器通信失效影响DSC的问题;推导了MFAC-DSC系统收敛性,给出了稳定收敛条件。基于交直流微电网实验平台在多种工况下验证了MFAC-DSC的可行性,与传统的DSC策略的对比结果表明:MFAC-DSC方法有效减少分布式电源下垂系数变化带来的功率波动,保证下垂系数有更大的调节范围,同时解决了互联变流器通信失效造成的控制失效和母线电压偏移等问题。

关键词：交直流微电网无模型自适应控制分布式二次控制功率分配

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集配协同下多产品越库配送车辆路径问题研究

武汉理工大学学报（交通科学与工程版） 2024年第2期48卷 385-391页

作者：王长琼杨畅武汉理工大学交通与物流工程学院武汉430063

文中基于实际越库配送中零售商的多样化需求和集配过程的连续型,针对集配协同下的多产品车辆路径问题,构建以车辆固定成本、运输成本、时间窗惩罚成本和库存持有成本最小化为目标的带越库配送的车辆路径优化模型.根据问题的阶段性特征,... 详细信息

文中基于实际越库配送中零售商的多样化需求和集配过程的连续型,针对集配协同下的多产品车辆路径问题,构建以车辆固定成本、运输成本、时间窗惩罚成本和库存持有成本最小化为目标的带越库配送的车辆路径优化模型.根据问题的阶段性特征,提出一种改进的遗传算法对问题进行求解,并以车辆等待时间最小为准则设计解码方案.通过算例的对比分析,验证了改进的遗传算法有更强的寻优能力.结果表明:建立的模型能够有效降低总成本,提高运输效率.

关键词：越库配送集配协同车辆路径问题改进遗传算法

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基于深度全卷积提升网络的心电信号降噪

计算机应用与软件 2024年第5期41卷 40-48页

作者：杨畅刘慧妍刘明河北大学电子信息工程学院河北省数字医疗工程重点实验室河北保定071002

针对传统的降噪方法难以在不丢失心电信号下准确去除复杂噪声问题,提出一种基于深度全卷积提升网络(FCBN)的心电信号降噪方法。该方法利用全卷积网络的局部连接的特性来保留心电信号波形细节信息,通过提升(Boosting)算法堆叠多个FCN网... 详细信息

针对传统的降噪方法难以在不丢失心电信号下准确去除复杂噪声问题,提出一种基于深度全卷积提升网络(FCBN)的心电信号降噪方法。该方法利用全卷积网络的局部连接的特性来保留心电信号波形细节信息,通过提升(Boosting)算法堆叠多个FCN网络形成深度神经网络,多级输入原始信号,保留心电信号的深层信息特征,提高整体网络的降噪性能。实验结果表明,该方法与小波阈值法、S变换法、BP神经网络法和卷积自动编码器比较,信噪比提高明显且均方根误差较小,同时可保留更多心电信号的波形形态信息。

关键词：心电信号降噪全卷积网络提升算法