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Downregulation of KIF1B mRNA in hepatocellular carcinoma tissues correlates with poor prognosis

World Journal of Gastroenterology 2015年第27期21卷 8418-8424页

作者： Song-Zhu yang Jian-Tao Wang Wei-Wei Yu qing Liu yan-Fang Wu Shu-Guang Chen Department of Hepatobiliary Surgery Yantaishan Hospital Department of Surgery Peking Union Medical College Hospital Chinese Academy of Medical Sciences and Peking Union Medical College

AIM: To compare kinesin family member 1B(KIF1B) expression with clinicopathologic parameters and prognosis in hepatocellular carcinoma(HCC) ***: KIF1 B protein and m RNA expression was assessed in HCC and paracarcinomatous(PC) tissues from 68 patients with HCC using Western blot and quantitative real-time reverse transcription-PCR, respectively. Student's t-tests were used to analyze relationships between clinicopathologic parameters and KIF1 B expression, the Kaplan-Meier method was used to analyze survival outcomes, and the log-rank test was used to compare survival differences between ***: Mean protein and m RNA levels of KIF1 B were similar between HCC and PC tissues. However, HCC tissues with vein invasions had significantly lower KIF1 B protein levels compared to those without vein invasions(2.30 ± 0.82 relative units vs 2.77 ± 0.84 relative units, P < 0.05). KIF1 B protein levels in HCC tissues from patients with recurrence during the followup period were significantly lower than those without recurrence(2.31 ± 0.92 relative units vs 2.80 ± 0.80 relative units, P < 0.05). However, KIF1 B protein and m RNA expression in HCC patients was not associated with other clinicopathologic parameters. Ratios of KIF1 B m RNA expression in HCC tissues to those in PC tissues were correlated with overall survival(13.5 mo vs 20.0 mo, P < 0.05) and disease-free survival(11.5 mo vs 19.5 mo, P < 0.05).CONCLUSION: Downregulation of KIF1 B in HCC tissues is associated with poor prognosis; additional clinical studies are needed to confirm whether KIF1 B can serve as a prognostic marker.

关键词： Clinicopathologic correlation Kinesin familymember 1B Liver cancer Survival Tumor progression

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Influence of Post-annealing in N2 on Structure and Electrochemical Characteristics of LiNi0.5Mn1.5O4

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Chemical Research in Chinese Universities 2013年第2期29卷 329-332页

作者： HE Shi-ci ZHANG Qian LIU Wei-wei FANG guo-qing SATO Yuichi ZHENG Jun-wei LI De-cheng Institute of Chemical Power Sources Soochow University Suzhou 215006 P. R. China Department of Applied Chemistry Faculty of Engineering Kanagawa University Yokohama 221-8686 Japan

LiNi0.5Mn1.504 prepared by a spray drying method was re-treated in N2 at 500, 600 and 700℃, respec- tively. Their structural and electrochemical properties were studied by means of Fourier transform infrared（FTIR）, X-ray diffraction（XRD）, and charge-discharge tests. The space group of the ***.504 transforms from P4332 to Fd3m at an annealing temperature of 700℃. The electrochemical characteristics of the treated samples are closely related to the annealing temperature. The sample treated in N2 at 500℃ shows both an improved rate capability and cyclic performance at a high temperature compared with the as-prepared sample, while the sample treated in N2 at 700℃ shows dramatically decrease in its reversible capacity.

关键词： Li-ion battery Cathode material LiNio.sMnl.504 Structural and electrochemical property

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Progress in Significant Soil Science Fields of China over the Last Three Decades: A Review

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Pedosphere 2011年第1期21卷 1-10页

作者： ZHAO Qi-guo HE Ji-Zheng yan Xiao-Yuan ZHANG Bin ZHANG Gan-Lin CAI Zu-Cong State Key Laboratory of Soil and Sustainable Agriculture Institute of Soil Science Chinese Academy of Sciences Nanjing 210008 (China) State Key Laboratory of Urban and Regional Ecology Research Centre for Eco-Environmental Sciences Chinese Academy of Sciences Beijing 100085 (China) Key Laboratory of Plant Nutrition and Nutrient Cycling of the Ministry of Agriculture of China Institute of Agricultural Resources and Regional Planning Chinese Academy of Agricultural Sciences Beijing 100081 (China)

Due to continuous decreases in arable land area and continuous population increases,Chinese soil scientists face great challenges in meeting food demands,mitigating adverse environmental impacts,and sustaining or enhancing soil productivity under intensive *** the aim of promoting the application of soil science knowledge,this paper reviews the achievements of Chinese scientists in soil resource use and management,soil fertility,global change mitigation and soil biology over the last 30 *** this period,soil resource science has provided essential support for the use and exploitation of Chinese soil resources,and has itself developed through introduction of new theories such as Soil Taxonomy and new technologies such as remote *** fertility science has contributed to the alleviation and elimination of impeding physical and chemical factors that constrain availability of essential nutrients and water in soils,the understanding of nutrient cycling in agroecosystems,and the increase in nutrient use efficiency for sustainable crop *** soil scientists have contributed to the understanding of the cropland's role in global change,particularly to the understanding of methane and nitrous oxide emission from rice fields and the effect of elevated carbon dioxide and ozone on rice-wheat *** biology research has progressed in biological N fixation,distribution of fauna in Chinese soils,and bioremediation of polluted soils.A new generation of soil scientists has arisen in the last three *** gaps between research and application in these soil science fields are also discussed.

关键词： global change soil biology soil fertility soil resources

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Fracture mechanism of a laminated aluminum alloy plate during ballistic impact

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Rare Metals 2017年第9期36卷 737-745页

作者： Ming-Yuan Li Bai-qing Xiong guo-Jun Wang You-Zhi Tong Xi-Wu Li Shu-Hui Huang Zhi-Hui Li Yong-An Zhang State Key Laboratory of Nonferrous Metals and Processes General Research Institute for Nonferrous MetalsBeijing 100088China Northeast Light Alloy Co. Ltd.Harbin 150060China

The multilayered 7XXX series aluminum alloy was impacted by 7.62 mm ogival projectiles at velocities ranging from 787 to 851m·s^（-1）. The deformed microstructure under various impacting velocities and fracture surfaces of different sections were investigated at different physical scales to determine the process of *** microscopy（OM）,electron back-scattered diffraction（EBSD） and scanning electron microscopy（SEM） were used in the investigation. The results show that crater is constrained in the 7B52 front layer and two types of adiabatic shear bands which are transformed bands and deformed bands and different types of cracks are *** fracture is the significant failure mode of 7B52 front layer, and the resulting delamination leads to the presence of bending tensile fracture instead of the shear *** ductile 7A01 layer blunts and deflects the spall crack tips, preventing the targets from full spall, and induces a constraint of 7A52 rear layer. The level of the constraint determines different fracture modes of 7A52 layer,accounting for the asymmetry of damage.

关键词： Laminate Aluminum Ballistic impact Spallfracture Adiabatic shear bands

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Adsorption and Corrosion Inhibition Performances of 1-Tetradecylphosphonic Acid Self-Assembled Monolayers on 430 Stainless Steel Surface

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Journal of Iron and Steel Research International 2013年第9期20卷 93-98页

作者： WANG Hai-ren JIANG yan QU Jun-e CAO Zhi-yong LIU Shao-bo guo Xing-peng Department of Chemistry Huazhong University of Science and Technology Faculty of Materials Science and Engineering Hubei University

The self-assembled monolayers （SAMs） of 1 tetradecylphosphonic acid （TDPA） formed on the 430 stain-less steel （SS430）were studied. Surface and morphological characterizations were studied by Fourier transformed in-frared spectroscopy （FTIR）, water contact angle measurement and atomic force microscopy （AFM）. And the elec-trochemical study on the corrosion inhihition of the SAMs was performed by polarization curve and electrochemical impedance spectroscopy （E1S） for evaluating the corrosion protection of the SAMs. The results show that TDPA was able to form a film spontaneously on the SS430 surface and the hydrophobic SAMs could protect SS430 from corrosion effectively. In addition, the oxide surface formed by the heat pretreatment could accelerate the rate of ad-sorption, but had little effect on improving the inhibition efficiency.

关键词： 1 tetradecylphosphonic acid self-assembled monolayer corrosion 430 stainless steel

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An impregnation-reduction method to prepare graphite nanosheet/alumina composites and its high-frequency dielectric properties

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Rare Metals 2017年第3期36卷 205-208页

作者： Ke-Lan yan Run-Hua Fan Min Chen Kai Sun Xu-Ai Wang qing Hou Shi-Bing Pan Ming-Xun Yu Key Laboratory for Liquid-Solid Structural Evolution and Processing of Materials(Ministry of Education) Shandong UniversityJinan 250061China Shandong Non-Metallic Materials Research Institute Jinan 250031 China

he nano-graphite sheet/alumina composites were prepared in situ by a facile impregnation-reduction *** microstructure of the composites was analyzed by X-ray diffraction （XRD）,and the final phase composition after reduction is Al2O3,metal Fe and graphite *** electron microscopy （SEM） images show that the particle size of Fe is about 20 nm,and the lamellae thickness of the graphite is about 30 ***,the dielectric properties and conductive mechanism of the composites were investigated experimentally in the frequency range of 0.01-1.00 GHz by impedance *** results show that the real part of permittivity of composites increases with Fe3＋ concentration,which is due to the increase in interfacial polarization between Fe and A12O3 and the three-dimensional network of lamellar graphite ***,tunable microtopography and electrical parameters of nano-graphite sheet/alumina composites can be realized by changing Fe3＋ concentration.

关键词： Impregnation-reduction method Ceramicmatrix composites Graphite sheet Complex permittivity Conductivity

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Influence of carbonization temperature on cobalt-based nitrogendoped carbon nanopolyhedra derived from ZIF-67 for nonoxidative propane dehydrogenation

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Petroleum Science 2023年第1期20卷 559-568页

作者： Yu-Ming Li Zi-Ye Liu Qi-yang Zhang Ya-Jun Wang guo-qing Cui Zhen Zhao Chun-Ming Xu Gui-Yuan Jiang State Key Laboratory of Heavy Oil Processing China University of PetroleumBeijing102249China

Propylene is a significant basic material for petrochemicals such as polypropylene,propylene oxide,*** abundant propane supply from shale gas,propane dehydrogenation(PDH)becomes extensively attractive as an on-purpose propylene production route in recent ***-doped carbon(NC)nanopolyhedra supported cobalt catalysts were synthesized in one-step of ZIF-67 pyrolysis and investigated further in ***,TEM and N_(2) adsorption-desorption were used to study the influence of carbonization temperature on as-prepared NC supported cobalt *** temperature is found to affect the cobalt phase and nitrogen species of the *** the positive correlation was established between Co0 proportion and space time yield of propylene,indicating that the modulation of carbonization temperature could be important for catalytic performance.

关键词： Propane dehydrogenation ZIF-67 Nitrogen-doped carbon Cobalt

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Pathological Changes in the Sinoatrial Node Tissues of Rats Caused by Pulsed Microwave Exposure

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Biomedical and Environmental Sciences 2015年第1期28卷 72-75页

作者： LIU yan qing GAO Ya Bing DONG Ji YAO Bin Wei ZHAO Li PENG Rui Yun Department of Experimental Pathology Beijing Institute of Radiation Medicine The Affiliated Hospital of Logistic College of Chinese People’s Armed Police Forces

To observe microwave induced dynamic pathological changes in the sinus nodes, wistar rats were exposed to 0, 5, 10, 50 mW/cm^2 microwave. In 10 and 50 mW/cm^2 groups, disorganized sinoatrial node cells, cell swelling, cytoplasmic condensation, nuclear pyknosis, and anachromasis, swollen, and empty mitochondria, and blurred and focally dissolved myofibrils could be detected from 1 to 28 d, while reduced parenchymal cells, increased collagen fibers, and extracellular matrix remodeling of interstitial cells were observed from 6 to 12 months. In conclusion, 10 and 50 mW/cm^2 microwave could cause structural damages in the sinoatrial node and extracellular matrix remodeling in rats.

关键词： Figure Pathological Changes in the Sinoatrial Node Tissues of Rats Caused by Pulsed Microwave Exposure

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De-farming and Ecological Restoration in the Loess Hilly-gully Region in Northern China

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Journal of Mountain Science 2006年第2期3卷 168-177页

作者： XU Yong TANG qing MA Dingguo guo Tengyun Institute of Geographic Sciences and Natural Resources Research CAS Beijing 100101 China

De-farming has been a powerful measure taken by the central and local governments of China for ecological restoration in the loess hilly-gully region since 2000. In years past, aid-based de-farming pattern was far and wide popularized in the region and terrace-based de-farming pattern demonstrated in a few small watersheds was also rather effective for ecological restoration. After summing up the features of three patterns (aid-based de-farming slope farmland more than 25°(AD25), aid-based de-farming slope farmland more than 15° (AD15) and terrace-based de-farming (TD)), this paper analyzed the regional difference of these patterns in de-farming area, ecological restoration, investment demand and so on. The results show that there are two crucial areas in the loess hilly-gully region for ecological restoration at the moment, the policies adaptation to the different areas should be constituted as soon as possible and the limited fund should be devoted to the two crucial areas.

关键词： De-farming ecological restoration loess hilly-gully region China

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Gallbladder bleeding along with cholecystocolonic fistula:a case report

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Gastroenterology Report 2021年第1期9卷 81-84,I0003页

作者： Hai-Lin yan Bo Lin qing Lu Tian-Tian Lei Hong-Sheng Ma Jin-Lin yang Department of Gastroenterology West China Hospital of Sichuan UniversityChengduSichuanP.R.China Department of Day Surgery West China Hospital of Sichuan UniversityChengduSichuanP.R.China

Introduction Gallstone disease is a major public-health problem,with a high prevalence ranging from 10%to 15%[1].Acute cholecystitis,chronic cholecystitis,choledocholithiasis,and gallstone pancreatitis are all common complications in clinical ***,when gallstones migrate to adjacent viscera or vascular structures,the clinical challenge is far less familiar[2].Gallbladder(GB)bleeding is seldom reported,which mostly manifests as *** cases are caused by cystic artery aneurysm and rupture and others are due to GB rupture[3].Gallstones can erode through the gallbladder wall or bile duct into the adjacent portion,resulting in a cholecystocolonic fistula(CCF),which is a rare complication of gallstones with cholecystitis[4].Here,we share a case of gallbladder bleeding along with cholecystocolonic fistula that has not yet been *** hope that,through our unusual case,clinicians gain an enhanced understanding of rare complications caused by gallstones.

关键词： cholecystitis rupture bleeding

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