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SPEECH EMOTION RECOGNITION USING MODIFIED QUADRATIC DISCRIMINATION FUNCTION

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Journal of Electronics(China) 2008年第6期25卷 840-844页

作者： zhao yan zhao li Zou Cairong Yu Yinhua School of Information Science and Technology Southeast University Nanjing 210096 China

Quadratic Discrimination Function （QDF） is commonly used in speech emotion recognition, which proceeds on the premise that the input data is normal distribution. In this paper, we propose a transformation to normalize the emotional features, emotion recognition. Features based on prosody then derivate a Modified QDF （MQDF） to speech and voice quality are extracted and Principal Component Analysis Neural Network （PCANN） is used to reduce dimension of the feature vectors. The results show that voice quality features are effective supplement for recognition, and the method in this paper could improve the recognition ratio effectively.

关键词： Speech emotion recognition Principal Component Analysis Neural Network (PCANN) Modified Quadratic Discrimination Function (MQDF)

Coexistent vestibular schwannoma and meningioma in a patient without neurofibromatosis:A case report and review of literature

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World Journal of Clinical Cases 2021年第24期9卷 7251-7260页

作者： li-yan zhao Yi-Ning Jiang Yu-Bo Wang yang Bai Ying Sun Yun-Qian li Department of Clinical Laboratory Second Hospital of Jilin UniversityChangchun 130041Jilin ProvinceChina Department of Neurosurgery First Hospital of Jilin UniversityChangchun 130021Jilin ProvinceChina

BACKGROUND The simultaneous occurrence of schwannoma and meningioma in the absence of neurofibromatosis(NF)or a previous history of irradiation is exceedingly rare,as only 10 intracranial cases have been reported to ***,we report a case of a coexistent cavernous sinus meningioma and ipsilateral vestibular schwannoma(VS)in a female patient without NF or a history of exposure to *** SUMMARY A 63-year-old woman presented with progressive left-side hearing loss and tinnitus over the previous *** the past 6 mo,she developed facial numbness and intermittent *** resonance imaging showed two lesions that were located on the left side of the cerebellopontine angle and parasellar *** lesions were totally resected via the left retrosigmoid *** examination revealed a VS and a *** patient did not have a family history or clinical or radiological signs of *** The coincident occurrence of VS and meningioma within close vicinity is very rare,and the pathogenesis is unclear.A careful whole-body examination needs to be conducted to exclude *** treatment with the goal of total tumor resection is the best *** studies are needed for a better understanding of the mechanisms that lead to the development of tumor growth in multiple locations.

关键词： Concurrent Diagnosis Meningioma Neurofibromatosis Schwannoma Case report

Effectiveness of enhanced recovery after surgery in the perioperative management of patients with bone surgery in China

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World Journal of Clinical Cases 2021年第33期9卷 10151-10160页

作者： li-yan zhao Xiong-Tao liu Zhi-li zhao Ru Gu Xiu-Mei Ni Rui Deng Xiao-Ying li Ming-Ji Gao Wei-Na Zhu Department of Anesthesiology The Second Affiliated Hospital of Xi’an Jiaotong UniversityXi'an 710004Shaanxi ProvinceChina Department of Anesthesiology PLA Air Force 986 HospitalXi'an 710054Shaanxi ProvinceChina

BACKGROUND Enhanced recovery after surgery(ERAS)was introduced in China in *** time,the scope of ERAS has expanded from abdominal surgery to orthopedics,urology and other *** development and research has contributed to progress of ERAS in *** 2019,to promote the application of ERAS in bone tumor surgery,we formed the“Consensus of Experts on Perioperative Management of Accelerated Rehabilitation in Major Surgery of Bone Tumors in China”.AIM To evaluate the effect of enhanced recovery after bone tumor surgery in perioperative management in *** One hundred and seven patients who underwent bone tumor surgery at the Second Affiliated Hospital of Xi’an Jiaotong University between May 2019 and April 2021 were randomized into a study group(53 cases)and a control group(54 cases).The study group adopted the ERAS protocol and the control group adopted conventional *** outcome measures included postoperative length of stay(LOS),postoperative complications,mortality,and 30-d readmission *** outcomes included postoperative visual analog scale(VAS)score of pain,number of blood transfusions,drainage volume in 24 h after operation,patient satisfaction 30 d after discharge,VAS score at 30 d after discharge,and daily standing walking *** There were no significant differences in the baseline data,clinical features and surgical site between the two *** LOS in the study group with the ERAS protocol was 7.72±3.34 d compared with 10.28±4.27 d in the control group who followed conventional *** incidence of postoperative nausea and vomiting(PONV)in the study group was 19%and 37%in the control *** VAS scores of pain on postoperative day 1(POD1)and POD3 in the study group were 4.79±2.34 and 2.79±1.53 compared with 5.28±3.27 and 3.98±2.27 in the control *** drainage volume in 24 h after the operation was 124.36±23.43 mL in the study group and 167.43±30.87 mL in the control *** number of blood transfusion

关键词： Enhanced recovery after surgery Bone tumor surgery Perioperative management Effect evaluation Clinical application

Scopolamine causes delirium-like brain network dysfunction and reversible cognitive impairment without neuronal loss

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Zoological Research 2023年第4期44卷 712-724页

作者： Qing Wang Xiang Zhang Yu-Jie Guo Ya-yan Pang Jun-Jie li yan-li zhao Jun-Fen Wei Bai-Ting Zhu Jing-Xiang Tang yang-yang Jiang Jie Meng Ji-Rong Yue Peng Lei Department of Geriatrics and State Key Laboratory of Biotherapy National Clinical Research Center for GeriatricsWest China HospitalSichuan UniversityChengduSichuan 610041China Pediatric Research Institute Ministry of Education Key Laboratory of Child Development and DisordersNational Clinical Research Center for Child Health and DisordersChongqing Key Laboratory of Translational Medical Research in Cognitive Development and Learning and Memory DisordersChildren's Hospital of Chongqing Medical UniversityChongqing 400014China

Delirium is a severe acute neuropsychiatric syndrome that commonly occurs in the elderly and is considered an independent risk factor for later ***,given its inherent complexity,few animal models of delirium have been established and the mechanism underlying the onset of delirium remains ***,we conducted a comparison of three mouse models of delirium induced by clinically relevant risk factors,including anesthesia with surgery(AS),systemic inflammation,and neurotransmission *** found that both bacterial lipopolysaccharide(LPS)and cholinergic receptor antagonist scopolamine(Scop)induction reduced neuronal activities in the delirium-related brain network,with the latter presenting a similar pattern of reduction as found in delirium ***,Scop injection resulted in reversible cognitive impairment with hyperactive *** loss of cholinergic neurons was found with treatment,but hippocampal synaptic functions were *** findings provide further clues regarding the mechanism underlying delirium onset and demonstrate the successful application of the Scop injection model in mimicking delirium-like phenotypes in mice.

关键词： Delirium Scopolamine Cholinergic neuron Neuronal activity Brain network

Imaging findings and transcatheter arterial chemoembolization of hepatic malignancy with right atrial embolus in 46 patients

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World Journal of Gastroenterology 2008年第22期14卷 3563-3568页

作者： Hong-yan Cheng Xiao-yan Wang Guo-li zhao Dong Chen Department of Radiology Eastern Hepatobiliary Surgery Hospital 225 Changhai Road Shanghai 200438 China

AIM: To analyze the imaging findings of hepatic malignancy with right atrial (RA) embolus. METHODS: Forty-six patients with an embolus in the RA were diagnosed, including 44 patients with hepatocellular carcinoma (HCC), 1 patient with cholangiocellular carcinoma and 1 patient with hepatic carcinoma metastasis. The diagnosis was confirmed by clinical examination, serum α-fetoprotein and imaging. Seventeen patients underwent transcatheter arterial chemoembolization (TACE). RESULTS: On enhancement computer tomography (CT) or magnetic resonance (MR) imaging, a nodular filling defect in the RA could be easily found, with a slight enhancement in the arterial phase. The coronal images of CT or MR showed the extent of lesion. lipiodol entered the embolus after TACE, hence reducing the speed of embolus growth. There was a survival benefit for patients receiving anticancer treatment. CONCLUSION: Patients with HCC, showing a filling defect of the inferior vena cava (IVC), hepatic vein (HV) and RA on images, can be diagnosed with RA embolus. Encroachment of the RA is very rare in patients with hepatic malignancies. Furthermore, a prolongation of survival time is found in those patients who underwent TACE.

关键词： Carcinoma liver Neoplasm Metastasis Embolus Right atrium Computed tomography X-Ray Magnetic resonance

A MICROSTRUCTURAL ANALYSIS OF 7050 Al ALLOY

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Acta Metallurgica Sinica(English Letters) 1992年第2期5卷 69-75页

作者： JIN yan li Chunzhi zhao Yingtao yan Minggao Beijing Institute of Aeronautical Materials.Beijing,China

The microstructure of 7050 AI alloy in T74 condition has been studied by means of transmis- sion electron microscopy and dynamical diffraction *** was found that the alloy studied contains mainly AI3Zr superlattice phase,η′-phase and Al_7Cu_2Fe constituent phase. The η′-phase has an orthorombic crystal structure with a=0.492 nm,b=0.852 nm and c=0.701 *** orientation relationship between the η′-phase and matrix was determined as(101)_m∥(010)_(η′)[111]_m∥[001]_(η′)

关键词： 7050 Al alloy microstructure TEM dynamical diffraction simulation

Chemical constituents from Munronia sinica and their bioactivities

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Natural Products and Bioprospecting 2012年第2期2卷 76-80页

作者： Xiao-li li Qiu-Xia HE Feng-Lei ZHANG yan-li zhao Ke-Chun liU Si-Ping JIANG Key Laboratory of Economic Plants and Biotechnology Kunming Institute of BotanyChinese Academy of SciencesKunming 650201China State Institute of Tibetan Plateau Research at Kunming Kunming Institute of BotanyChinese Academy of SciencesKunming 650201China Biology Institute of Shandong Academy of Sciences Jinan 250014China Kunming City Institute of Materia Medica Kunming 650051China Plateau Institute of Biology Lhasa 850000China

Two new minor constituents,musinisins A(1)and B(2),together with five known compounds(3-7),were isolated from the aerial parts of Munronia *** structures were established by means of spectroscopic methods and the absolute stereochemistry of 1 was determined by single crystal X-ray *** 4 showed antiangiogenic activity evaluated by a zebrafish model and apoptosis-inducing effect on A549 lung cancer cells.

关键词： Munronia sinica chemical constituent musinisin antiangiogenic activity

SOX7 is involved in aspirin-mediated growth inhibition of human colorectal cancer cells

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World Journal of Gastroenterology 2011年第44期17卷 4922-4927页

作者： Xin Zhou Shu-yan Huang Jing-Xin Feng yan-yan Gao li zhao Jun Lu Bai-Qu Huang Yu Zhang The Institute of Genetics and Cytology School of Life Science Northeast Normal University Changchun 130024 Jilin Province China

AIM:To confirm the role of sex-determining region Y-box 7(Sox7) in aspirin-mediated growth inhibition of COX-independent human colorectal cancer ***:The cell survival percentage was examined by MTT(Moto-nuclear cell direc cytotoxicity) ***7 expression was assessed by using reverse transcription-polymerase chain reaction and Western ***203580 was used to inhibit the p38MAPK signal ***7 promoter activity was detected by Luciferase reporter ***:SOX7 was upregulated by aspirin and was involved in aspirin-mediated growth inhibition of SW480 human colorectal cancer *** p38MAPK pathway played a role in aspirin-induced SOX7 expression,during which the AP1 transcription factors c-Jun and c-Fos upregulated SOX7 promoter ***:SOX7 is upregulated by aspirin and is involved in aspirin-mediated growth inhibition of human colorectal cancer SW480 cells.

关键词： SOX7 Aspirin p38MAPK Colorectal cancer SB203580

Sleep-associated movement disorders and the risk of cardiovascular disease: A systematic review and metaanalysis

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World Journal of Meta-Analysis 2015年第3期3卷 181-187页

作者： Zhen Fang Yao-Wu liu li-yan zhao yan Xu Feng-Xiang Zhang Department of Cardiology the First Affiliated Hospital of Nanjing Medical University

AIM:To investigate whether an association exists between sleep-associated movement disorders and cardiovascular disease(CVD).METHODS:Several studies have observed the relationship of sleep-associated movement disorders such as restless legs syndrome(RLS)and periodic limb movements during sleep with CVD,but the results were still *** performed an extensive literature search on Pub Med,Medline and Web of Science published from inception to December *** studies were manually searched from bibliographies of retrieved ***-analyses were conducted with Stata version 12.0(Stata Corp,College Station,Texas).Pooled odds ratios(ORs)and 95%CIs were calculated to assess the strength of association using the random effects *** and subgroup analyses were performed to explore the underlying sources of *** publication bias was detected using Egger’s test and Begg’s ***:A total of 781 unique citations were indentified from electronic databases and 13 articles in English were finally *** these studies,nine are cohort studies;two are case-control studies;and two are cross-sectional *** results showed that the summary OR of CVD associated with sleepassociated movement was 1.51(95%CI:1.29-1.77)in a random-effects *** was significant heterogeneity between individual studies(P for heterogeneity=0.005,I2=57.6%).Further analysis revealed that a large-scale cohort study may account for this heterogeneity.A significant association was also found between RLS and CVD(OR=1.54,95%CI:1.24-1.92).In a fixed-effects model,we determined a significant relationship between sleep-associatedmovement disorders and coronary artery disease(CAD)(OR=1.34,95%CI:1.16-1.54;P for heterogeneity=0.210;I2=30.0%).Our meta-analysis suggests that sleep-associated movement disorders are associated with prevalence of CVD and ***:This finding indicates that sleep-associated movement disorders may prove to be predictiv

关键词： Sleep-associated movement disorders Restless legs syndrome Cardiovascular disease Metaanalysis Periodic limb movements during sleep