Chemical constituents from Munronia sinica and their bioactivities

作     者：Xiao-Li LI Qiu-Xia HE Feng-Lei ZHANG Yan-Li ZHAO Ke-Chun LIU Si-Ping JIANG 

作者机构：Key Laboratory of Economic Plants and BiotechnologyKunming Institute of BotanyChinese Academy of SciencesKunming 650201China State Institute of Tibetan Plateau Research at KunmingKunming Institute of BotanyChinese Academy of SciencesKunming 650201China Biology Institute of Shandong Academy of SciencesJinan 250014China Kunming City Institute of Materia MedicaKunming 650051China Plateau Institute of BiologyLhasa 850000China 

出 版 物：《Natural Products and Bioprospecting》 (应用天然产物（英文）)

年 卷 期：2012年第2卷第2期

页      面：76-80页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

基　　金：supported financially by the Bureau of Science and Technology of Kunming City 

主　　题：Munronia sinica chemical constituent musinisin antiangiogenic activity 

摘      要：Two new minor constituents,musinisins A(1)and B(2),together with five known compounds(3-7),were isolated from the aerial parts of Munronia *** structures were established by means of spectroscopic methods and the absolute stereochemistry of 1 was determined by single crystal X-ray *** 4 showed antiangiogenic activity evaluated by a zebrafish model and apoptosis-inducing effect on A549 lung cancer cells.