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W, Mo, Co Co-diffusion on Steel with Different Carbon Content

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材料热处理学报 2004年第05B期25卷 688-691页

作者： ZHANGyan-mei LIZhong-hou LIUyan-ping xuZhong ResearchInstituteofSurfaceEngineering TaiyuanUniversityofTechnologyTaiyuanChina

Tungsten, molybdenum and cobalt were co-diffused into the surface of ingot, 20 steel, 45 steel and T8 steel by a double glow plasma surface alloying technique. Surface alloyed layers formed on ingot and 20 steel are composed of -Fe +(Fe,Co)7(W,Mo)6, which possess the same strong age-hardening ability as the metallurgical age-hardened high speed steel, the maximum hardness can reach 1100 HV0.o25 after ageing treatment. Surface alloyed layers formed on 45 steel and T8 steel are composed of M6C, hardness of which are over 1100-1400 HV0.o25- Alloyed layers formed on ingot and 20 steel possess good toughness. Alloyed layer of carbide type exhibits slightly brittleness.

关键词：碳含量表面铸合碳钢硬度脆性钼钴共扩散

Association between UCP3 gene polymorphisms and nonalcoholic fatty liver disease in Chinese children

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World Journal of Gastroenterology 2013年第35期19卷 5897-5903页

作者： yan-ping xu Li Liang Chun-Lin Wang Jun-Fen Fu Pei-Ning Liu Lan-Qiu Lv Yi-Min Zhu Department of Endocrinology Children’s Hospital of Zhejiang University School of Medicine Department of Pediatrics the First Affiliated Hospital College of Medicine Zhejiang University Department of Child Health Care the Affiliated Yuying Children’s Hospital of Wenzhou Medical University Department of Child Health Care Ningbo Women and Children’s Hospital Department of Epidemiology and Biostatistics Key Laboratory of Reproductive Genetics Ministry of Education Zhejiang University

AIM:To confirm the hypothesis that polymorphisms of the uncoupling protein 3(UCP3)gene are associated with the occurrence of nonalcoholic fatty liver disease(NAFLD).METHODS:A total of 250 NAFLD patients(147 malesand 103 females)and 200 healthy individuals who served as controls(control,109 males and 91 females),aged between 6 and 16 years were enrolled in this *** four non-synonymous single nucleotide polymorphisms(SNPs)in the UCP3 gene polymorphisms of rs1726745,rs3781907,rs11235972 and rs1800849,were genotyped using *** mass index(BMI),waist and hip circumference,blood pressure(BP),fasting blood glucose(FBG),insulin and lipid profiles were measured and B-ultrasound examination was performed in all ***:NAFLD patients showed risk factors for metabolic syndrome:elevated BMI,waist-to-hip ratio,BP,FBG,homeostasis model assessment-estimated insulin resistance,total triglyceride,total cholesterol and low-density lipoprotein-cholesterol,while decreased high-density lipoprotein-cholesterol level compared with the control *** GG genotype distributions of rs11235972 in the NAFLD group differed significantly from that in the control *** found that waist circumference between CC(58.76±6.45 cm)and CT+TT(57.00±5.59 cm),and hip circumference between CC(71.28±7.84 cm)and CT+TT genotypes(69.06±7.75 cm)were significantly different with and without rs1800849 variation(P<0.05).CONCLUSION:A higher prevalence of rs11235972 GG genotype was observed in the NAFLD group compared with the control *** differences were observed for the other ***,there was a significant difference in body height in addition to waist and hip circumference between the CC(mutant type group)and CT+TT group with and without rs1800849 variation.

关键词： Nonalcoholic fatty liver disease Uncoupling protein 3 Single nucleotide polymorphisms

Battling against the novel coronavirus: control strategies for and clinical management of the 2019 novel coronavirus infection in Shanghai, China

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Chinese Medical Journal 2020年第20期133卷 2395-2397页

作者： Jing-Ya Zhao Jing Zhang yan-ping xu Jia-yang yan Jin-Fu xu Jie-Ming Qu Department of Pulmonary and Critical Care Medicine Ruijin HospitalShanghai Jiaotong University School of MedicineShanghai 200025China Department of Pulmonary and Critical Care Medicine Zhongshan HospitalFudan UniversityShanghai 200032China Department of Pulmonary and Critical Care Medicine Shanghai Pulmonary HospitalTongji University School of MedicineShanghai 200433China

At the end of 2019,presentation of viral pneumonia due to a novel coronavirus(2019 novel coronavirus)was reported in a group of patients in Wuhan,Hubei Province,China.111 Now,coronavirus disease 2019(COVID-19)has pose... 详细信息

关键词： Wuhan Hubei management

Establishing a new testing protocol of the electrochemical stability window for electric double-layer capacitors

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Science China Chemistry 2025年第1期68卷 217-225页

作者： Ruilin Hou Xiaoxi Zhao Tingting Liang Qingyun Dou Shan xu Xingbin yan School of Materials Science and Engineering Sun Yat-sen University Laboratory of Clean Energy Chemistry and Materials Lanzhou Institute of Chemical Physics Chinese Academy of Sciences College of Engineering and Applied Sciences Nanjing University Center of Industrial Analysis and Testing Guangdong Academy of Science

The electrochemical stability window(ESW) is crucial for determining the energy density of electric double-layer capacitors(EDLCs). However, current ESW testing protocols of EDLCs are strongly affected by artificial factors, thereby leading to unreliable result. To solve this problem, we first identify the key shortcomings of the traditional protocols by analyzing their test principles. Subsequently, taking an aqueous carbon-based EDLC as an example, we design a side reaction descriptor to represent the response difference in the charging capacitance to side reactions between the cyclic voltammetry and galvanostatic chargedischarge methods. With the aid of this descriptor, we propose a new ESW testing protocol, which is not only able to completely avoid the adverse influence of subjective factors but also fully consider the operating condition limitations. The protocol can be extended from the single electrode to the full device. This work proposes a more rigorous definition of ESW and provides a reliable protocol for evaluating the ESW of EDLCs.

关键词： electric double-layer capacitors electrochemical stability window testing protocol side reaction descriptor operating limitation

Pathogenesis, diagnosis, and treatment of epilepsy: electromagnetic stimulation-mediated neuromodulation therapy and new technologies

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Neural Regeneration Research 2025年第4期20卷 917-935页

作者： Dian Jiao Lai xu Zhen Gu Hua yan Dingding Shen Xiaosong Gu Academy of Medical Engineering and Translational Medicine Tianjin UniversityTianjinChina Key Laboratory of Advanced Drug Delivery Systems of Zhejiang Province College of Pharmaceutical SciencesZhejiang UniversityHangzhouZhejiang ProvinceChina Affiliated Hospital of Nantong University NantongJiangsu ProvinceChina

Epilepsy is a severe,relapsing,and multifactorial neurological *** regarding the accurate diagnosis,prognosis,and in-depth pathogenesis are crucial for the precise and effective treatment of *** pathogenesis of epilepsy is complex and involves alterations in variables such as gene expression,protein expression,ion channel activity,energy metabolites,and gut microbiota *** results are lacking for conventional treatments for *** resection of lesions,drug therapy,and non-drug interventions are mainly used in clinical practice to treat pain associated with ***-pharmacological treatments,such as a ketogenic diet,gene therapy for nerve regeneration,and neural regulation,are currently areas of research *** review provides a comprehensive overview of the pathogenesis,diagnostic methods,and treatments of *** also elaborates on the theoretical basis,treatment modes,and effects of invasive nerve stimulation in neurotherapy,including percutaneous vagus nerve stimulation,deep brain electrical stimulation,repetitive nerve electrical stimulation,in addition to non-invasive transcranial magnetic stimulation and transcranial direct current *** studies have shown that electromagnetic stimulation-mediated neuromodulation therapy can markedly improve neurological function and reduce the frequency of epileptic ***,many new technologies for the diagnosis and treatment of epilepsy are being ***,current research is mainly focused on analyzing patients’clinical manifestations and exploring relevant diagnostic and treatment methods to study the pathogenesis at a molecular level,which has led to a lack of consensus regarding the mechanisms related to the disease.

关键词： diagnosis drug treatment electroencephalography epilepsy monitoring epilepsy nerve regeneration neurostimulation non-drug interventions pathogenesis prediction

Recombinant chitinase-3-like protein 1 alleviates learning and memory impairments via M2 microglia polarization in postoperative cognitive dysfunction mice

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Neural Regeneration Research 2025年第9期20卷 2727-2736页

作者： Yujia Liu xue Han yan Su Yiming Zhou Minhui xu Jiyan xu Zhengliang Ma Xiaoping Gu Tianjiao Xia Department of Anesthesiology Nanjing Drum Tower HospitalAffiliated Hospital of Medical SchoolNanjing UniversityNanjingJiangsu ProvinceChina Medical School Nanjing UniversityNanjingJiangsu ProvinceChina Jiangsu Key Laboratory of Molecular Medicine Nanjing UniversityNanjingJiangsu ProvinceChina State Key Laboratory of Pharmaceutical Biotechnology Nanjing UniversityNanjingJiangsu ProvinceChina Department of Anesthesiology Zhongshan HospitalFudan UniversityShanghaiChina

Postoperative cognitive dysfunction is a seve re complication of the central nervous system that occurs after anesthesia and surgery,and has received attention for its high incidence and effect on the quality of life of *** date,there are no viable treatment options for postoperative cognitive *** identification of postoperative cognitive dysfunction hub genes could provide new research directions and therapeutic targets for future *** identify the signaling mechanisms contributing to postoperative cognitive dysfunction,we first conducted Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analyses of the Gene Expression Omnibus GSE95426 dataset,which consists of mRNAs and long non-coding RNAs differentially expressed in mouse hippocampus3 days after tibial *** dataset was enriched in genes associated with the biological process"regulation of immune cells,"of which Chill was identified as a hub ***,we investigated the contribution of chitinase-3-like protein 1 protein expression changes to postoperative cognitive dysfunction in the mouse model of tibial fractu re *** were intraperitoneally injected with vehicle or recombinant chitinase-3-like protein 124 hours post-surgery,and the injection groups were compared with untreated control mice for learning and memory capacities using the Y-maze and fear conditioning *** addition,protein expression levels of proinflammatory factors(interleukin-1βand inducible nitric oxide synthase),M2-type macrophage markers(CD206 and arginase-1),and cognition-related proteins(brain-derived neurotropic factor and phosphorylated NMDA receptor subunit NR2B)were measured in hippocampus by western *** with recombinant chitinase-3-like protein 1 prevented surgery-induced cognitive impairment,downregulated interleukin-1βand nducible nitric oxide synthase expression,and upregulated CD206,arginase-1,pNR2B,and brain-derived neurotropic factor expr

关键词： Chil1 hippocampus learning and memory M2 microglia neuroinflammation postoperative cognitive dysfunction(POCD) recombinant CHI3L1

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多目标联合优化的移动中继选择策略

北京邮电大学学报 2016年第3期39卷 120-125页

作者：赵季红张艳平曲桦徐西光西安交通大学电信学院西安710049 西安邮电大学通信与信息工程学院西安710061

为了在提升用户吞吐量的同时降低中继节点切换概率,分析了动态场景下用户与中继节点的移动状态,提出了多目标联合优化的移动中继选择策略.算法通过分析动态场景中影响系统吞吐量与中继切换概率的因素进行中继节点选择,充分考虑了多跳蜂... 详细信息

为了在提升用户吞吐量的同时降低中继节点切换概率,分析了动态场景下用户与中继节点的移动状态,提出了多目标联合优化的移动中继选择策略.算法通过分析动态场景中影响系统吞吐量与中继切换概率的因素进行中继节点选择,充分考虑了多跳蜂窝网络的移动特性和用户呼叫到达状态.仿真结果表明,所提算法在有效提升用户吞吐量的同时降低了中继切换概率.

关键词：多跳蜂窝网络吞吐量中继切换概率多目标联合优化

Analysis of Micromechanical Properties at the Interface of Pre-wet SBS Modified Asphalt Mixture Based on Molecular Simulation Technology

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Journal of Wuhan University of Technology(Materials Science) 2025年第1期40卷 103-113页

作者： CHEN Wuxing CHEN Shuang YU yan ZHANG Jiangyi xu Haiyang GUO Wei School of Mines China University of Mining and TechnologyXuzhou 221000China College of Construction Engineering Jilin Uni-versityChangchun 130026China

The pre-wetting of aggregate surface is a means to improve the interface performance of SBS modified asphalt and *** effect of pre-wetting technology on the interaction between SBS modified asphalt and aggregate was analyzed by molecular dynamics *** diffusion coefficient and concentration distribution of SBS modified asphalt on aggregate surface are *** simulation results show that the diffusion coefficient of the aggregate surface of SBS modified asphalt is increased by 47.6%and 70.5%respectively after 110#asphalt and 130#asphalt are *** concentration distribution of SBS modified asphalt on the aggregate surface after pre-wetting is more *** to the results of interface energy calculation,the interface energy of SBS modified bitumen and aggregate can be increased by about 5%after *** to the results of molecular dynamics simulation,the pre-wetting technology can effectively improve the interface workability of SBS modified bitumen and aggregate,so as to improve the interface performance.

关键词： pre-wet oil-stone interface interface interaction interface mechanics molecular dynamics simulation

Investigating the p-Ω interactions and correlation functions

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Science China(Physics,Mechanics & Astronomy) 2025年

作者： Ye yan Qi Huang Youchang yang Hongxia Huang Jialun ping Department of Physics Nanjing Normal University School of Science Guizhou University of Engineering Science

Motivated by experimental measurements, we investigate the p-Ω correlation functions and interactions on the basis of a quark model. By solving the inverse scattering problem with channel coupling, we renormalize the coupling to other channels into an effective single-channel p-Ω potentials. The effects of Coulomb interaction and spin-averaging are also discussed. According to our results, the depletion of the p-Ω correlation functions, which is attributed to the JP= 2+bound state not observed in the ALICE Collaboration's measurements(Nature 588, 232（2020）), can be explained by the contribution of the attractive JP= 1+component in spin-averaging. So far, we have provided a consistent description of the p-Ω system from the perspective of the quark model, including the energy spectrum, scattering phase shifts, and correlation functions. The existence of the p-Ω bound state has been supported by all three aspects. Additionally, a sign of the p-Ω correlation function's subtle sub-unity part can be seen in experimental measurements, which warrants more precise verification in the future.

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