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MoS_(2)Lubricate‑Toughened MXene/ANF Composites for Multifunctional Electromagnetic Interference Shielding

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Nano-Micro Letters 2025年第2期17卷 358-371页

作者： Jiaen Wang Wei ming Longfu Chen Tianliang Song Moxi Yele Hao Zhang Long yang Gegen Sarula Benliang Liang Luting yan Guangsheng Wang School of Physical Science and Engineering Beijing Jiaotong UniversityBeijing 100044People’s Republic of China Key Laboratory of Bio‑Inspired Smart Interfacial Science and Technology of Ministry of Education School of ChemistryBeihang UniversityBeijing 100191People’s Republic of China

The design and fabrication of high toughness electromagnetic interference(EMI)shielding composite films with diminished reflection are an imperative task to solve electromagnetic pollution *** MXene/ANF(aramid nanofibers)–MoS_(2)composite films with nacre-like layered structure here are fabricated after the introduction of MoS_(2)into binary MXene/ANF composite *** introduction of MoS_(2)fulfills an impressive“kill three birds with one stone”improvement effect:lubrication toughening mechanical performance,reduction in secondary reflection pollution of electromagnetic wave,and improvement in the performance of photothermal *** the introduction of MoS_(2)into binary MXene/ANF(mass ratio of 50:50),the strain to failure and tensile strength increase from 22.1±1.7%and 105.7±6.4 MPa and to 25.8±0.7%and 167.3±9.1 MPa,*** toughness elevates from 13.0±4.1 to 26.3±0.8 MJ m^(−3)(~102.3%)*** the reflection shielding effectiveness(SE_(R))of MXene/ANF(mass ratio of 50:50)decreases~10.8%.EMI shielding effectiveness(EMI SE)elevates to 41.0 dB(8.2–12.4 GHz);After the introduction of MoS_(2)into binary MXene/ANF(mass ratio of 60:40),the strain to failure increases from 18.3±1.9%to 28.1±0.7%(~53.5%),the SE_(R)decreases~22.2%,and the corresponding EMI SE is 43.9 *** MoS_(2)also leads to a more efficient photothermal conversion performance(~45 to~55℃).Additionally,MXene/ANF–MoS_(2)composite films exhibit excellent electric heating performance,quick temperature elevation(15 s),excellent cycle stability(2,2.5,and 3 V),and long-term stability(2520 s).Combining with excellent mechanical performance with high MXene content,electric heating performance,and photothermal conversion performance,EMI shielding ternary MXene/ANF–MoS_(2)composite films could be applied in many industrial *** work broadens how to achieve a balance between mechanical properties and versatility of composites in the case of high-function fillers.

关键词： MXene-MoS_(2) Lubrication toughening EMI shielding Photothermal conversion Electric heating performance

Human-induced pluripotent stem cell-derived neural stem cell exosomes improve blood-brain barrier function after intracerebral hemorrhage by activating astrocytes via PI3K/AKT/MCP-1 axis

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Neural Regeneration Research 2025年第2期20卷 518-532页

作者： Conglin Wang Fangyuan Cheng Zhaoli Han Bo yan Pan liao Zhenyu Yin Xintong Ge Dai Li Rongrong Zhong Qiang Liu Fanglian Chen Ping Lei Department of Geriatrics Tianjin Medical University General HospitalTianjinChina School of Medicine Nankai UniversityTianjinChina Tianjin Neurological Institute TianjinChina

Cerebral edema caused by blood-brain barrier injury after intracerebral hemorrhage is an important factor leading to poor ***-induced pluripotent stem cell-derived neural stem cell exosomes(hiPSC-NSC-Exos)have shown potential for brain injury repair in central nervous system *** this study,we explored the impact of hiPSC-NSC-Exos on blood-brain barrier preservation and the underlying *** results indicated that intranasal delivery of hiPSC-NSC-Exos mitigated neurological deficits,enhanced blood-brain barrier integrity,and reduced leukocyte infiltration in a mouse model of intracerebral ***,hiPSC-NSC-Exos decreased immune cell infiltration,activated astrocytes,and decreased the secretion of inflammatory cytokines like monocyte chemoattractant protein-1,macrophage inflammatory protein-1α,and tumor necrosis factor-αpost-intracerebral hemorrhage,thereby improving the inflammatory *** sequencing indicated that hiPSC-NSC-Exo activated the PI3K/AKT signaling pathway in astrocytes and decreased monocyte chemoattractant protein-1 secretion,thereby improving blood-brain barrier *** with the PI3K/AKT inhibitor LY294002 or the monocyte chemoattractant protein-1 neutralizing agent C1142 abolished these *** summary,our findings suggest that hiPSC-NSC-Exos maintains blood-brain barrier integrity,in part by downregulating monocyte chemoattractant protein-1 secretion through activation of the PI3K/AKT signaling pathway in astrocytes.

关键词： AKT astrocyte blood-brain barrier cerebral edema exosomes human-induced pluripotent stem cells intracerebral hemorrhage neural stem cells neuroinflammation PI3K

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接枝型聚砜膜的制备及其CO2分离性能

精细化工 2018年第4期35卷 625-630页

作者：李晓翠阮雪华侯勇焉晓明廖绪行贺高红大连理工大学精细化工国家重点实验室石油与化学工程学院

以商业化芳族聚合物聚砜（PSf）、氯甲基辛基醚（CMOE）和1-甲基咪唑为原料,通过简单可控的氯甲基化和咪唑钅翁化反应,制备接枝型聚离子液体——咪唑钅翁化聚砜（PSf-g-[MIm][Cl]）,以其为分离层制备PSf-g-[MIm][Cl]膜。通过1HNMR、SEM... 详细信息

以商业化芳族聚合物聚砜（PSf）、氯甲基辛基醚（CMOE）和1-甲基咪唑为原料,通过简单可控的氯甲基化和咪唑钅翁化反应,制备接枝型聚离子液体——咪唑钅翁化聚砜（PSf-g-[MIm][Cl]）,以其为分离层制备PSf-g-[MIm][Cl]膜。通过1HNMR、SEM与TGA对膜进行了表征,并考察了咪唑钅翁化程度（DIm）、操作温度、操作压力对膜性能的影响。结果表明：该膜材料具有较好的压力稳定性,可耐受0.6 MPa的压力,并且咪唑钅翁（MIm）基团含量会极大地影响其性能,随着DIm的提高,膜内MIm基团逐渐形成连续的传递通道,CO2渗透系数和选择性显著提高。在DIm=172%、操作温度25℃、操作压力0.4 MPa及增湿条件下进行膜性能测试,CO2渗透系数达到66.4 barrer,CO2/N2选择性（渗透系数的比,下同）为118.4。

关键词：聚离子液体侧链接枝促进传递咪唑钅翁 CO2分离分离技术

Mathematical simulation and observation of ground subsidence basin in coal mining area

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中国有色金属学会会刊：英文版 2005年第S1期15卷 25-27页

作者： JIANG Chen-guang~1, HE Yong~2, yan Li-ming~3, liao ming-quan~4, LUAN Yong-jian~2, LIU Yu-rong~3 (1. Southern yangtze University, Jiangsu Wuxi 214063, China 2. Laiyang Agricultural College, Shandong 265200, China 3. Kangping Supervision Agent Co. of Laiyang City, Shandong 265200, China 4. Chongqing Coal Mine Design and Research Institute, Chongqing 400037, China) So yangtze Univ Jiangsu 214063 Wuxi Peoples R China Laiyang Agr Coll Shandong 265200 Peoples R China Kangping Supervis Agent Co Laiyang City Shandong 265200 Peoples R China Chongqing Coal Mine Design & Res Inst Chongqing 400037 Peoples R China

Based on a great amount of practically observational data and by computer simulation, a formula for estimating the ground subsidence caused by coal mining was derived. Meanwhile, an empirical mathematical model for gr... 详细信息

关键词： coal mining ground subsidence basin estimation formula empirical mathematical model

舒血宁注射液治疗心血管疾病安全性的系统评价

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中国中西医结合杂志 2017年第3期37卷 283-290页

作者：陈红玉谢雁鸣廖星陈媛媛中国中医科学院中医临床基础医学研究所北京100700 中国中医科学院望京医院信息中心北京100102 中国中医科学院广安门医院放射科北京100053

目的系统评价舒血宁注射液治疗符合适应症的心血管疾病的安全性。方法 2015年10月通过计算机检索Cochrane图书馆、Medline、EMBase、Web of Science、Clinical Trials、中国生物医学文献数据库(CBM)、中国知网(CNKI)、维普(VIP)、万方... 详细信息

目的系统评价舒血宁注射液治疗符合适应症的心血管疾病的安全性。方法 2015年10月通过计算机检索Cochrane图书馆、Medline、EMBase、Web of Science、Clinical Trials、中国生物医学文献数据库(CBM)、中国知网(CNKI)、维普(VIP)、万方数据库和中国临床试验注册中心数据库,收集关于应用舒血宁注射液治疗心血管疾病用药安全性的所有研究类型文献。根据纳入、排除标准筛选并提取资料。所纳入研究包括随机对照试验、非随机对照试验、观察性研究(病例对照、队列研究、病例系列、病例报告等),分别采用Cochrane系统评价员手册5.1.0偏倚风险评估工具、TREND非随机对照研究报告规范、SUMARI进行方法学质量评价。结果共纳入185篇文献,其中随机对照试验155篇,非随机对照试验6篇,病例系列11篇,病例报告13篇。纳入13篇病例报告中,出现不良反应15例。在155篇RCT研究中,使用舒血宁注射液患者共8 553例,出现不良反应162例,4例发生不良事件;不良反应结局主要是对胃肠系统、中枢及外周神经系统、皮肤及其附件损害等,损害程度多为轻度;不能明确舒血宁注射液不良反应发生与用药剂量、方式、溶媒、联合用药的关系。结论舒血宁注射液治疗心血管疾病总体安全性可接受,现虽系统分析了关于舒血宁注射液安全性病例报告的直接证据,但缺少针对该药安全性的机理研究或临床观察性研究。

关键词：舒血宁注射液心血管疾病安全性不良反应/事件系统评价

CPM领导行为评价计算机信息处理软件系统的研究与设计

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天津理工大学学报 1989年第1期19卷 37-44页

作者：黄永康严隽佩严明廖津玲天津理工学院计算机工程与数学系

对领导个体及群体的测评是干部制度改革中的一项重要工作。本文所述的 CPM 领导行为测评方法是从领导行为的角度进行测评的科学方法,有效地应用该方法的关键是研制一套 CPM 领导行为测评计算机信息处理系统。本文扼要介绍了 CPM 测评方... 详细信息

对领导个体及群体的测评是干部制度改革中的一项重要工作。本文所述的 CPM 领导行为测评方法是从领导行为的角度进行测评的科学方法,有效地应用该方法的关键是研制一套 CPM 领导行为测评计算机信息处理系统。本文扼要介绍了 CPM 测评方法,对计算机测评过程进行了系统分析,讨论了系统的总体结构设计及其实现,并着重说明了在设计与实现中为该系统的优化所考虑的若干较为重要的技术问题及采取的相应措施.它将在信息处理与计算机化的干部测评系统的研制等方面提供有益的参考。

关键词：办公室自动化管理信息系统领导行为测评

Chondroitinase ABC combined with Schwann cell transplantation enhances restoration of neural connection and functional recovery following acute and chronic spinal cord injury

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Neural Regeneration Research 2025年第5期20卷 1467-1482页

作者： Wenrui Qu Xiangbing Wu Wei Wu Ying Wang yan Sun Lingxiao Deng Melissa Walker Chen Chen Heqiao Dai Qi Han Ying Ding Yongzhi Xia George Smith Rui Li Nai-Kui Liu Xiao-ming Xu Spinal Cord and Brain Injury Research Group Stark Neurosciences Research InstituteDepartment of Neurological SurgeryIndiana University School of MedicineIndianapolisINUSA Department of Hand Surgery the Second Hospital of Jilin UniversityChangchunJilin ProvinceChina Shriners Hospitals Pediatric Research Center Temple University School of MedicinePhiladelphiaPAUSA Department of Anatomy&Cell Biology Indiana University School of MedicineIndianapolisINUSA

Schwann cell transplantation is considered one of the most promising cell-based therapy to repair injured spinal cord due to its unique growth-promoting and myelin-forming properties.A the Food and Drug Administration-approved Phase I clinical trial has been conducted to evaluate the safety of transplanted human autologous Schwann cells to treat patients with spinal cord injury.A major challenge for Schwann cell transplantation is that grafted Schwann cells are confined within the lesion cavity,and they do not migrate into the host environment due to the inhibitory barrier formed by injury-induced glial scar,thus limiting axonal reentry into the host spinal *** we introduce a combinatorial strategy by suppressing the inhibitory extracellular environment with injection of lentivirus-mediated transfection of chondroitinase ABC gene at the rostral and caudal borders of the lesion site and simultaneously leveraging the repair capacity of transplanted Schwann cells in adult rats following a mid-thoracic contusive spinal cord *** report that when the glial scar was degraded by chondroitinase ABC at the rostral and caudal lesion borders,Schwann cells migrated for considerable distances in both rostral and caudal *** Schwann cell migration led to enhanced axonal regrowth,including the serotonergic and dopaminergic axons originating from supraspinal regions,and promoted recovery of locomotor and urinary bladder ***,the Schwann cell survival and axonal regrowth persisted up to 6 months after the injury,even when treatment was delayed for 3 months to mimic chronic spinal cord *** findings collectively show promising evidence for a combinatorial strategy with chondroitinase ABC and Schwann cells in promoting remodeling and recovery of function following spinal cord injury.

关键词： axonal regrowth bladder function chondroitinase ABC functional recovery glial scar lentivirus migration Schwann cell spinal cord injury transplantation

An NMR-spectroscopy-based Metabonomic approach to the analysis of Bay41-4109,a novel anti-HBV compound,induced hepatotoxicity in rats

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An NMR-spectroscopy-based Metabonomic approach to the analys...

员工主动性人格与创新行为的关系:基于趋利-避害框架理论的实证研究

中国毒理学会第三届中青年学者科技论坛暨2011年全国前列腺药理毒理学研讨会

作者： Chang Shi~a,Chun-qi Wu~a,An-min Cao~a,He-Zhang Sheng~a,Qi Zhang~b,Xian-zhong yan~b, ming-yang liao~(a*) a Beijing Institute of Pharmacology and Toxicology,Beijing 100850,P.R.China b National Center of Biochemical Analysis,Beijing 100850,P.R.China

An integrated metabonomics study using high-resolution H NMR spectroscopy has been applied to investigate the biochemical composition of urine,serum,liver tissue aqueous extracts(acetonitrile/water)and liver tissue lipidic extracts(chloroform/methanol) obtained from control and Bay41-4109 treated rats(10,50,400mg·kg·dfor 5 days,i.g.)or phenobarbital treated rats(60mg·kg·dfor 5 days,i.p.).Principal components analysis was used to visualize similarities and differences in biochemical *** results showed the biochemical profiles of 400mg·kg·dgroup might reflect the hepatotoxicity of Bay41-4109 more *** elevation in the level of 3-HB,lactate,2-hydroxy-acetol,hydroxymaleic acid and d-glucose was found in the urine,and the levels of VLDL/LDL(CH)n, VLDL/LDL-CH,2-oxo-3-methyl-n-valerate,3-HB,lactate,pyruvate,taurine, 3-amino-isovalerate,2-hydroxy-isovalerate in serum were increased significantly in 400mg·kg·*** predominant changes identified in liver tissue aqueous extracts included an increase in the signal intensities of lactate,3-amino-isovalerate,pyruvate,taurine, choline,TMAO and a reduction in the intensities of trytophan and *** liver tissue chloroform/methanol extracts,there was a remarkably increase in many of the lipid signals including the triglyceride terminal methyl,methylene groups,and CHCO,N(CH), CHOPO,*** observations all provide evidence that fatty acid metabolism disorder and mitochondrial inability might contribute to the hepatotoxicity of Bay41-4109. There were similarities and differences between the mechanisms of the hepatotoxicity of Bay41-4109 and *** application of H NMR spectroscopy to an array of biological samples comprising urine,serum and liver tissue extracts yields new insight into the hepatotoxicity of xenobiotics.

关键词： Bay41-4109 ~1H NMR spectroscopy Metabonomics Hepatotoxicity Pattern recognition

来源： cnki会议评论

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管理工程学报 2025年第2期39卷 41-56页

作者：严鸣赵楚铃朱瑜邬金涛暨南大学管理学院中山大学岭南学院

员工的创新行为能为员工个体和组织带来益处,但同时也会给员工带来较大风险,而现有研究未解决员工在面对潜在风险时仍会表现出创新行为这个问题。本文基于趋利-避害框架理论,通过163个团队的489份数据,探讨了趋利型/避害型主动性人格影... 详细信息

员工的创新行为能为员工个体和组织带来益处,但同时也会给员工带来较大风险,而现有研究未解决员工在面对潜在风险时仍会表现出创新行为这个问题。本文基于趋利-避害框架理论,通过163个团队的489份数据,探讨了趋利型/避害型主动性人格影响员工不同类型创新行为的内在作用机制和边界条件。研究发现,趋利型主动性人格通过机会发掘动机间接影响增益型创新行为,而避害型主动性人格通过问题发掘动机间接影响避害型创新行为。团队内授权氛围不仅会调节趋利型主动人格与机会发掘动机的关系,还会进一步调节趋利型主动型人格通过机会发掘动机间接影响增益型创新行为的关系。同时,团队间竞争氛围可以调节避害型主动人格与问题发掘动机的关系,进一步调节避害型主动型人格通过问题发掘动机间接影响避害型创新行为的关系。本文在理论上有助于澄清主动性人格的实质及其对不同类型创新行为的影响效应和作用机制,为提高企业创新行为管理水平提供管理启示。

关键词：主动性人格创新行为趋利避害框架理论团队内授权氛围团队间竞争氛围

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