检索结果-南通市图书馆

Anionic passivation layer-assisted trapping of an icosahedral Ag_(13)kernel in a truncated tetrahedral Ag_(89)nanocluster

在线全文

学校读者我要写书评

暂无评论

Science China Chemistry 2021年第9期64卷 1482-1486页

作者： yan-min su Bao-Qian Ji Zhi Wang Shan-Shan Zhang Lei Feng Zhi-Yong Gao Yun-Wu Li Chen-Ho Tung Di sun Lan-sun Zheng Key Lab of Colloid and Interface Chemistry Ministry of EducationSchool of Chemistry and Chemical EngineeringState Key Laboratory of Crystal MaterialsShandong UniversityJinan250100China School of Chemistry and Chemical Engineering Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine ChemicalsKey Laboratory of Green Chemical Media and ReactionsMinistry of EducationHenan Normal UniversityXinxiang453007China Shandong Provincial Key Laboratory of Chemical Energy Storage and Novel Cell Technology School of Chemistry and Chemical EngineeringLiaocheng UniversityLiaocheng252000China State Key Laboratory for Physical Chemistry of Solid surfaces Department of ChemistryCollege of Chemistry and Chemical EngineeringXiamen UniversityXiamen361005China

Isolating reductive silver kernel from shell is a challenging task but is quite important to understand the embryonic form during the formation of silver *** intercalation of suitable anionic species may be of benefit for passivating then capturing such highly active ***,we successfully isolated a novel silver thiolate nanocluster[Ag_(13)@Ag_(76)S_(16)(Cyh S)_(42)(p-NH_(2)-Ph As O_(3))_(4)]^(3+)(SD/Ag89 a,Cyh SH=cyclohexanethiol)that contains a well-isolated icosahedral Ag_(13) kernel passivated by four Ag S_(4)^(7-) tetrahedra and four p-NH_(2) Ph As O_(3)^(2-) piercing from outer Ag_(72) *** note,this Ag_(13) kernel is the largest isolable subvalent silver kernel beneath the silver shell with extremely legible core-shell boundary ever before and represents a precise embryonic model formed in the reducing Ag(I)to Ag(0)followed by aggregating to large silver *** reductive role of DMF and the introduction of anionic passivation layer(APL)synergistically modulate the reduction kinetics,facilitating the capture of ultrasmall subvalent silver ***/Ag89 a emits in near infrared(NIR)region(λ_(em)=800 nm)at low *** synthetic strategy shown in this work opens up new opportunities for precisely capturing and recognizing diverse reductive silver kernels in different systems.

关键词： silver cluster anionic passivation layer X-ray structure luminescence

Glucocorticoid receptor signaling in the brain and its involvement in cognitive function

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第9期20卷 2520-2537页

作者： Chonglin su Taiqi Huang Meiyu Zhang yanyu Zhang yan Zeng Xingxing Chen Brain Science and Advanced Technology Institute Hubei Province Key Laboratory of Occupational Hazard Identification and ControlSchool of MedicineWuhan University of Science and TechnologyWuhanHubei ProvinceChina

The hypothalamic-pituitary-adrenal axis regulates the secretion of glucoco rticoids in response to environmental *** the brain,a nuclear receptor transcription fa ctor,the glucocorticoid recepto r,is an important component of the hypothalamicpituitary-a d renal axis's negative feedback loop and plays a key role in regulating cognitive equilibrium and *** glucoco rticoid receptor influences cognitive processes,including glutamate neurotransmission,calcium signaling,and the activation of brain-derived neurotrophic factor-mediated pathways,through a combination of genomic and non-genomic *** interactions within the central nervous system can alter the expression and activity of the glucocorticoid receptor,there by affecting the hypothalamic-pituitary-a d renal axis and stress-related cognitive *** appropriate level of glucocorticoid receptor expression can improve cognitive function,while excessive glucocorticoid receptors or long-term exposure to glucoco rticoids may lead to cognitive *** with cognitive impairment-associated diseases,such as Alzheimer's disease,aging,depression,Parkinson's disease,Huntington's disease,stroke,and addiction,often present with dysregulation of the hypothalamic-pituitary-adrenal axis and glucocorticoid receptor *** review provides a comprehensive overview of the functions of the glucoco rticoid receptor in the hypothalamic-pituitary-a d renal axis and cognitive *** emphasizes that appropriate glucocorticoid receptor signaling fa cilitates learning and memory,while its dysregulation can lead to cognitive *** provides clues about how glucocorticoid receptor signaling can be targeted to ove rcome cognitive disability-related disorders.

关键词： brain-derived neurotrophic factor calcium signaling glucocorticoid receptor glucocorticoid glutamate transmission hypothalamic-pituitary-adrenal axis long-term potentiation neurocognitive disorders neuroplasticity stress

Porous Organic Cage‑Based Quasi‑Solid‑State Electrolyte with Cavity‑Induced Anion‑Trapping Effect for Long‑Life Lithium Metal Batteries

在线全文

学校读者我要写书评

暂无评论

Nano-Micro Letters 2025年第2期17卷 376-386页

作者： Wei-min Qin Zhongliang Li Wen‑Xia su Jia‑min Hu Hanqin Zou Zhixuan Wu Zhiqin Ruan Yue‑Peng Cai Kang Li Qifeng Zheng School of Chemistry South China Normal UniversityGuangzhou 510006People’s Republic of China Key Laboratory of Functional Metal‑Organic Compounds of Hunan Province College of Chemistry and Material ScienceHengyang Normal UniversityHengyang 421008People’s Republic of China Guangzhou Key Laboratory of Energy Conversion and Energy Storage Materials Guangzhou 510006People’s Republic of China

Porous organic cages(POCs)with permanent porosity and excellent host–guest property hold great potentials in regulating ion transport behavior,yet their feasibility as solid-state electrolytes has never been testified in a practical ***,we design and fabricate a quasi-solid-state electrolyte(QSSE)based on a POC to enable the stable operation of Li-metal batteries(LMBs).Benefiting from the ordered channels and cavity-induced anion-trapping effect of POC,the resulting POC-based QSSE exhibits a high Li+transference number of 0.67 and a high ionic conductivity of 1.25×10^(−4) S cm^(−1) with a low activation energy of 0.17 *** allow for homogeneous Li deposition and highly reversible Li plating/stripping for over 2000 *** a proof of concept,the LMB assembled with POC-based QSSE demonstrates extremely stable cycling performance with 85%capacity retention after 1000 ***,our work demonstrates the practical applicability of POC as SSEs for LMBs and could be extended to other energy-storage systems,such as Na and K batteries.

关键词： Porous organic cage Cavity-induced anion-trapping Quasi-solid-state electrolyte Homogeneous Li+flux Lithium metal battery

Optimization of an Artificial Intelligence Database and Camera Installation for Recognition of Risky Passenger Behavior in Railway Vehicles

在线全文

学校读者我要写书评

暂无评论

Computers, Materials & Continua 2025年第1期82卷 1277-1293页

作者： min-kyeong Kim Yeong Geol Lee Won-Hee Park su-hwan Yun Tae-Soon Kwon Duckhee Lee Railroad Test&Certification Division Korea Railroad Research Institute(KRRI)Cheoldo BangmulgwanroUiwang-si16105Republic of Korea Railroad Safety Division Korea Railroad Research Institute(KRRI)Cheoldo BangmulgwanroUiwang-si16105Republic of Korea

Urban railways are vital means of public transportation in *** than 30%of metropolitan residents use the railways,and this proportion is expected to *** enhance safety,the government has mandated the installation of closed-circuit televisions in all carriages by ***,cameras still monitored *** address this limitation,we developed a dataset of risk factors and a smart detection system that enables an immediate response to any abnormal behavior and intensive monitoring *** created an innovative learning dataset that takes into account seven unique risk factors specific to Korean railway *** data collection was conducted across the Shinbundang Line of the Incheon Transportation Corporation,and the Ui-Shinseol *** observed several behavioral characteristics and assigned unique annotations to *** also considered carriage *** performance was evaluated by camera placement and *** the camera installation plan was *** dataset will find immediate applications in domestic railway *** artificial intelligence algorithms will be verified shortly.

关键词： AI railway vehicle risk factor smart detection AI training data

Recombinant chitinase-3-like protein 1 alleviates learning and memory impairments via M2 microglia polarization in postoperative cognitive dysfunction mice

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第9期20卷 2727-2736页

作者： Yujia Liu Xue Han yan su Yiming Zhou minhui Xu Jiyan Xu Zhengliang Ma Xiaoping Gu Tianjiao Xia Department of Anesthesiology Nanjing Drum Tower HospitalAffiliated Hospital of Medical SchoolNanjing UniversityNanjingJiangsu ProvinceChina Medical School Nanjing UniversityNanjingJiangsu ProvinceChina Jiangsu Key Laboratory of Molecular Medicine Nanjing UniversityNanjingJiangsu ProvinceChina State Key Laboratory of Pharmaceutical Biotechnology Nanjing UniversityNanjingJiangsu ProvinceChina Department of Anesthesiology Zhongshan HospitalFudan UniversityShanghaiChina

Postoperative cognitive dysfunction is a seve re complication of the central nervous system that occurs after anesthesia and surgery,and has received attention for its high incidence and effect on the quality of life of *** date,there are no viable treatment options for postoperative cognitive *** identification of postoperative cognitive dysfunction hub genes could provide new research directions and therapeutic targets for future *** identify the signaling mechanisms contributing to postoperative cognitive dysfunction,we first conducted Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analyses of the Gene Expression Omnibus GSE95426 dataset,which consists of mRNAs and long non-coding RNAs differentially expressed in mouse hippocampus3 days after tibial *** dataset was enriched in genes associated with the biological process"regulation of immune cells,"of which Chill was identified as a hub ***,we investigated the contribution of chitinase-3-like protein 1 protein expression changes to postoperative cognitive dysfunction in the mouse model of tibial fractu re *** were intraperitoneally injected with vehicle or recombinant chitinase-3-like protein 124 hours post-surgery,and the injection groups were compared with untreated control mice for learning and memory capacities using the Y-maze and fear conditioning *** addition,protein expression levels of proinflammatory factors(interleukin-1βand inducible nitric oxide synthase),M2-type macrophage markers(CD206 and arginase-1),and cognition-related proteins(brain-derived neurotropic factor and phosphorylated NMDA receptor subunit NR2B)were measured in hippocampus by western *** with recombinant chitinase-3-like protein 1 prevented surgery-induced cognitive impairment,downregulated interleukin-1βand nducible nitric oxide synthase expression,and upregulated CD206,arginase-1,pNR2B,and brain-derived neurotropic factor expr

关键词： Chil1 hippocampus learning and memory M2 microglia neuroinflammation postoperative cognitive dysfunction(POCD) recombinant CHI3L1

调督理筋针配合循经点刺治疗气滞血瘀型神经根型颈椎病临床观察

在线全文

学校读者我要写书评

暂无评论

河南中医 2023年第5期43卷 767-771页

作者：闫利敏闫素敏河南大学第一附属医院河南开封475000

目的:观察调督理筋针配合循经点刺治疗气滞血瘀型神经根型颈椎病的临床疗效。方法:本研究选取2018年6月至2022年8月河南大学第一附属医院收治的神经根型颈椎病患者126例,辨证为气滞血瘀证,按照随机数字表法分为观察组与对照组,每组63例... 详细信息

目的:观察调督理筋针配合循经点刺治疗气滞血瘀型神经根型颈椎病的临床疗效。方法:本研究选取2018年6月至2022年8月河南大学第一附属医院收治的神经根型颈椎病患者126例,辨证为气滞血瘀证,按照随机数字表法分为观察组与对照组,每组63例。对照组给予普通针刺疗法治疗,观察组给予调督理筋针配合循经点刺治疗。观察两组患者治疗前后疼痛视觉模拟评分(visual analogue score,VAS)、中医证候积分、颈椎功能障碍指数(neck disability index,NDI)评分变化情况及临床疗效。结果:观察组治疗后中医证候评分低于对照组,差异具有统计学意义(P<0.05);观察组治疗后VAS评分低于对照组,差异具有统计学意义(P<0.05);观察组治疗后NDI评分低于对照组,差异具有统计学意义(P<0.05);观察组有效率为90.48%,对照组有效率为73.02%,观察组有效率高于对照组,差异具有统计学意义(P<0.05)。结论:调督理筋针配合循经点刺治疗气滞血瘀型神经根型颈椎病,能够改善患者中医证候、颈椎功能障碍,缓解疼痛。

关键词：神经根型颈椎病气滞血瘀证调督理筋针循经点刺

在线全文

学校读者我要写书评

暂无评论

述情障碍与脑出血患者抑郁的相关性分析

中国康复 2014年第3期29卷 176-178页

作者：颜敏素毛小丹温岭市第一人民医院浙江温岭317500

目的:探讨述情障碍与脑出血患者抑郁的相关性。方法:采用多伦多述情障碍量表(TAS)和汉密尔顿抑郁量表(HAMD)对206例脑出血患者进行问卷调查,据此分为抑郁组和非抑郁组。首先,单因素分析比较2组基本资料的差别,然后采用多层回归分析法,... 详细信息

目的:探讨述情障碍与脑出血患者抑郁的相关性。方法:采用多伦多述情障碍量表(TAS)和汉密尔顿抑郁量表(HAMD)对206例脑出血患者进行问卷调查,据此分为抑郁组和非抑郁组。首先,单因素分析比较2组基本资料的差别,然后采用多层回归分析法,探讨述情障碍对脑出血患者抑郁的影响。结果:脑出血患者抑郁和述情障碍发生率分别为57.28%(118/206)和41.26%(85/206)。抑郁组TAS识别情感障碍、描述情感障碍、外向性思维评分及总分均显著高于非抑郁组(P<0.05)。Pearson相关分析提示,HAMD评分与TAS总分、识别情感障碍、描述情感障碍、外向性思维评分均显著正相关(r=0.389、0.374、0.281、0.456,P<0.05)。多元回归分析显示,述情障碍中的外向性思维、识别情感障碍均为脑出血患者抑郁的影响因素(P<0.05)。结论:述情障碍是脑出血患者抑郁的重要原因。

关键词：述情障碍抑郁脑出血

小针刀联合艾灸对慢性膝关节骨性关节炎患者疼痛及炎性因子的影响

在线全文

学校读者我要写书评

暂无评论

河南中医 2023年第4期43卷 593-597页

作者：闫素敏闫利敏韩柄秋河南大学第一附属医院河南开封475000 开封市中医院河南开封475000

目的:观察小针刀联合艾灸对阳虚寒凝型慢性膝关节骨性关节炎患者疼痛及炎性因子的影响。方法:选取2019年1月至2022年10月在河南大学第一附属医院收治的慢性膝关节骨性关节炎患者90例,按照随机数字表法分为观察组和对照组,每组45例。对... 详细信息

目的:观察小针刀联合艾灸对阳虚寒凝型慢性膝关节骨性关节炎患者疼痛及炎性因子的影响。方法:选取2019年1月至2022年10月在河南大学第一附属医院收治的慢性膝关节骨性关节炎患者90例,按照随机数字表法分为观察组和对照组,每组45例。对照组给予针刺联合艾灸治疗,观察组给予小针刀联合艾灸治疗。观察两组患者治疗前后西安大略和麦克马斯特大学骨关节炎指数(western ontario and mcmaster universities osteoarthritis index, WOMAC)、疼痛视觉模拟评分(visual analogue score, VAS)及炎性因子[白细胞介素(interleukin, IL)-1β、IL-6和肿瘤坏死因子(tumor necrosis factor, TNF)-α]变化情况。结果:观察组治疗后WOMAC评分、VAS评分低于对照组,差异有统计学意义(P<0.05);观察组治疗后IL-1β、IL-6、TNF-α水平低于对照组,差异具有统计学意义(P<0.05)。结论:小针刀联合艾灸治疗慢性膝关节骨性关节炎,能够改善患者骨关节炎指数,缓解疼痛,降低炎性因子水平。

关键词：慢性膝关节骨性关节炎阳虚寒凝证小针刀艾灸疼痛炎性因子

TRMT6 and TRMT61A facilitated acute pancreatitis severity via regulation of neutrophil function

在线全文

学校读者我要写书评

暂无评论

Science China Life Sciences 2025年

作者： Yuan Dong Li su Sin Man Lam Cen yan Yalan Deng Guotao Lu Jinkui yang Guanghou Shui Yingmei Feng Beijing Institute of Hepatology Beijing Youan HospitalCapital Medical University Department of Science and Development Beijing Youan HospitalCapital Medical University Laboratory for Clinical Medicine Capital Medical University Neuroscience Research Institute Peking University Center of Medical and Health AnalysisPeking University State Key Laboratory of Molecular Developmental Biology Institute of Genetics and Developmental BiologyChinese Academy of Sciences Pancreatic Center Department of GastroenterologyAffiliated Hospital of Yangzhou UniversityYangzhou University Beijing Key Laboratory of Diabetes Research and Care Department of EndocrinologyBeijing Tongren HospitalCapital Medical University

Dear Editor,Type 2 diabetes mellitus (T2DM) has been identified as a risk factor for increased severity in acute pancreatitis (AP)(Mikóet al,2018).However,to date,no studies have simultaneously included healthy individuals,T2DM patients,and AP patients to investigate which diabetes-associated metabolites are linked to AP severity.

关键词：