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WATuning:A Workload-Aware Tuning System with Attention-Based Deep Reinforcement Learning

Journal of Computer Science & Technology 2021年第4期36卷 741-761页

作者： Jia-Ke Ge yan-feng chai Yun-Peng chai Key Laboratory of Data Engineering and Knowledge Engineering of Ministry of Education Renmin University of China Beijing 100872China School of Information Renmin University of ChinaBeijing 100872China College of Computer Science and Technology Taiyuan University of Science and TechnologyTaiyuan 030027China

Configuration tuning is essential to optimize the performance of systems(e.g.,databases,key-value stores).High performance usually indicates high throughput and low *** present,most of the tuning tasks of systems are performed artificially(e.g.,by database administrators),but it is hard for them to achieve high performance through tuning in various types of systems and in various *** recent years,there have been some studies on tuning traditional database systems,but all these methods have some *** this article,we put forward a tuning system based on attention-based deep reinforcement learning named WATuning,which can adapt to the changes of workload characteristics and optimize the system performance efficiently and ***,we design the core algorithm named ATT-Tune for WATuning to achieve the tuning task of *** algorithm uses workload characteristics to generate a weight matrix and acts on the internal metrics of systems,and then ATT-Tune uses the internal metrics with weight values assigned to select the appropriate ***,WATuning can generate multiple instance models according to the change of the workload so that it can complete targeted recommendation services for different types of ***,WATuning can also dynamically fine-tune itself according to the constantly changing workload in practical applications so that it can better fit to the actual environment to make *** experimental results show that the throughput and the latency of WATuning are improved by 52.6%and decreased by 31%,respectively,compared with the throughput and the latency of CDBTune which is an existing optimal tuning method.

关键词： attention mechanism auto-tuning system reinforcement learning(RL) workload-aware

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Towards Data-Driving Multi-View Evaluation Framework for Scratch

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Tsinghua Science and Technology 2024年第2期29卷 517-528页

作者： Xiaolin chai yan Sun yan Gao Department of Computer Science Beijing University of Posts and TelecommunicationBeijing 100876China Intellectual Property Institute Shandong Polytechnic CollegeJining 272067China

As one of the most popular visual programming languages,Scratch has a lot of evaluation around *** evaluation can help programmers understand their projects *** the same time,it can also provide a reference for them to browse other projects in the online *** of the existing evaluations on Scratch are carried from three perspectives:Computational Thinking(CT)ability,visual presentation aesthetics,and code *** them,the assessment of CT and code quality is mainly carried out from the program script,while the evaluation of visual aesthetics is analyzed from the perspective of image sequences generated by project *** single-view evaluation focuses on the performance of a program in a certain aspect and is *** this paper,we propose a multi-view evaluation framework to integrate various evaluations using different *** quantitatively analyze the assessment of different views driven by *** with overall evaluations that represent human opinions,we analyze their differences and *** experiments,we determine the weights of different integration policies,the proposed multi-view evaluation method can generate evaluation results similar to human opinions.

关键词： Scratch Computational Thinking(CT) visual aesthetic static analysis integration policy machine learning

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Distributed Minimum-Energy Containment Control of Continuous-Time Multi-Agent Systems by Inverse Optimal Control

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IEEE/CAA Journal of Automatica Sinica 2024年第6期11卷 1533-1535页

作者： Fei yan Xiangbiao Liu Tao feng School of Information Science and Technology Southwest Jiaotong UniversityChengdu 611756China National Engineering Laboratory of Integrated Transportation Big Data Application Technology Chengdu 611756China

Dear Editor,This letter focuses on the distributed optimal containment control of continuous-time multi-agent systems(CTMASs)with respect to the minimum-energy performance index over fixed *** achieve this,we firstly investigate the optimal containment control problem using the inverse optimal control method,where all states of followers asymptotically converge to the convex hull spanned by the leaders while some quadratic performance indexes get minimized.A sufficient condition for existence of the distributed optimal containment control protocol is *** introducing the parametric algebraic Riccati equation(PARE),it is strictly proved that the global performance index can be used to approximate the standard minimumenergy performance index as the parameters tends to *** consequence,the standard minimum-energy cooperative containment control can be solved by local steady state feedback protocols.

关键词： optimal infinity algebraic

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A review on the transformation of birnessite in the environment:Implication for the stabilization of heavy metals

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Journal of Environmental Sciences 2024年第5期139卷 496-515页

作者： Miao Shi Qingzhu Li Qingwei Wang Xuelei yan Bensheng Li Linhai feng Chao Wu Rongrong Qiu Hongkai Zhang Zhihui yang Weichun yang Qi Liao Liyuan chai School of Metallurgy and Environment Central South UniversityChangsha 410083China National Engineering Research Centre for Control and Treatment ofHeavy Metal Pollution Central South UniversityChangsha 410083China Water Pollution Control Technology Key Lab of Hunan Province Changsha 410083China

Birnessite is ubiquitous in the natural environment where heavy metals are retained and easily *** surface properties and structure of birnessite change with the changes in external environmental conditions,which also affects the fate of heavy *** the effect and mechanism of the birnessite phase transition process on heavy metals is the key to taking effective measures to prevent and control heavy metal ***,the four transformation pathways of birnessite are summarized first in this ***,the relationship between transformation pathways and environmental conditions is *** relevant environmental conditions include abiotic(e.g.,co-existing ions,pH,oxygen pressure,temperature,electric field,light,aging,pressure)and biotic factors(e.g.,microorganisms,biomolecules).The phase transformation is achieved by the key intermediate of Mn(Ⅲ)through interlayer-condensation,folding,neutralizationdisproportionation,and dissolution-recrystallization *** AOS(average oxidation state)of Mn and interlayer spacing are closely correlated with the phase transformation of *** but not least,the mechanisms of heavy metals immobilization in the transformation process of birnessite are summed *** involve isomorphous substitution,redox,complexation,hydration/dehydration,*** transformation of birnessite and its implication on heavy metals will be helpful for understanding and predicting the behavior of heavy metals and the crucial phase of manganese oxides/hydroxides in natural and engineered environments.

关键词： Birnessite Transformation Heavy metals Pathways Mechanism

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High-efficiency crystalline white organic lightemitting diodes

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Light(Science & Applications) 2024年第4期13卷 747-759页

作者： Yijun Liu feng Zhu Yue Wang Donghang yan State Key Laboratory of Polymer Physics and Chemistry Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun 130022China. School of Applied Chemistry and Engineering University of Science and Technology of ChinaHefei 230026China. State Key Laboratory of Supramolecular Structure and Materials Jilin UniversityChangchun 130012China

Crystalline white organic light-emitting diodes(C-WOLEDs)are promising candidates for lighting and display *** is urgently necessary,however,to develop energy-saving and high-efficiency C-WOLEDs that have stable and powerful emission to meet commercial ***,we report a crystalline host matrix(CHM)with embedded nanoaggregates(NA)structure for developing high-performance C-WOLEDs by employing a thermally activated delayed fluorescence(TADF)material and orange phosphorescent dopants(Phos.-D).The CHM-TADFNA-D WOLED exhibit a remarkable EQE of 12.8%,which is the highest performance WOLEDs based on crystalline *** device has a quick formation of excitons and a well-designed energy transfer process,and possesses a fast ramping of luminance and current *** to recently reported high-performance WOLEDs based on amorphous material route,the C-WOLED achieves a low series-resistance Joule-heat loss ratio and an enhanced photon output,demonstrating its significant potential in developing the next-generation WOLEDs.

关键词： diodes dopant crystalline

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Porous silica nano-flowers stabilized Pt-Pd bimetallic nanoparticles as heterogeneous catalyst for efficiently synthesizing guaiacol from 2-methoxycyclohexanol

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Chinese Journal of Chemical Engineering 2024年第6期70卷 222-233页

作者： Junbo feng Junyan Wu Dongdong yan Yadong Zhang School of Chemical Engineering Zhengzhou UniversityZhengzhou 450001China State Key Laboratory of Coking Coal Exploitation and Comprehensive Utilization Pingdingshan 467000China Jiyuan Research Institute Zhengzhou UniversityJiyuan 459000China School of Materials and Chemical Engineering Zhongyuan University of TechnologyZhengzhou 450007China

Porous silica nano-flowers(KCC-1)immobilized Pt-Pd alloy NPs(Pt-Pd/KCC-1)with different mass ratios of Pd and Pt were successfully prepared by a facile in situ one-step reduction,using hydrazinium hydroxide as a reducing *** as-synthesized silica nanospheres possess radial fibers with a distance of 15 nm,exhibiting a high specific surface area(443.56 m^(2)·g^(-1)).Meanwhile,the obtained Pt-Pd alloy NPs are uniformly dispersed on the silica surface with a metallic particle size of 4-6 nm,which exist as metallic Pd and Pt on the surface of monodisperse KCC-1,showing the transfer of electrons from Pd to *** as-synthesized 2.5%Pt-2.5%Pd/KCC-1 exhibited excellent catalytic activity and stability for the continuous dehydrogenation of 2-methoxycyclohexanol to prepare *** with Pt or Pd single metal supported catalysts,the obtained 2.5%Pt-2.5%Pd/KCC-1 shows 97.2%conversion rate of 2-methoxycyclohexanol and 76.8%selectivity for guaiacol,which attributed to the significant synergistic effect of bimetallic Pt-Pd alloy ***,turn over frequency value of the obtained 2.5%Pt-2.5%Pd/KCC-1 NPs achieved 4.36 s^(-1),showing higher catalytic efficiency than other two monometallic *** pathways of dehydro-aromatization of 2-methoxycyclohexanol over the obtained catalyst are ***,the obtained 2.5%Pt-2.5%Pd/KCC-1 NPs prove their potential in the dehydrogenation of 2-methoxycyclohexanol,while the kinetics and mechanistic study of the dehydrogenation reaction over the catalyst in a continuous fixed-bed reactor may provide valuable information for the development of green,outstanding and powerful synthetic pathway of guaiacol.

关键词： Supported catalyst Nanoparticles Dehydrogenation 2-Methoxycyclohexanol Guaiacol

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Silencing MFN2 Drives WNT/β-catenin Nucleation to Reduce Sorafenib Sensitivity in Hepatocellular Carcinoma Cells

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Current Medical Science 2024年第4期44卷 789-798页

作者： chai-ming ZENG Bin SHAO yan-ping CHEN Gui-sheng DING Department of Geriatric Medicine Shengli Clinical Medical College of Fujian Medical UniversityFujian Key Laboratory of Geriatrics DiseasesFujian Provincial Center for GeriatricsFujian Provincial HospitalFuzhou350001China Department of Rehabilitation Shengli Clinical Medical College of Fujian Medical UniversityFujian Provincial HospitalFuzhou350001China Department of Gynecology Shengli Clinical Medical College of Fujian Medical UniversityFujian Provincial HospitalFuzhou350001China Department of Ultrasonography Shengli Clinical Medical College of Fujian Medical UniversityFujian Provincial HospitalFuzhou350001China

Objective Mitofusin-2(MFN2)is a mitochondrial membrane protein that plays a critical role in regulating mitochondrial fusion and cellular *** further elucidate the impact of MFN2,this study aimed to investigate its significance on hepatocellular carcinoma(HCC)cell function and its potential role in mediating *** This study investigated the effects of silencing and overexpressing MFN2 on the survival,proliferation,invasion and migration abilities,and sorafenib resistance of MHCC97-L HCC *** experiments were conducted using XAV939(aβ-catenin inhibitor)and HLY78(aβ-catenin activator)to further validate these *** Silencing MFN2 significantly promoted the survival and proliferation of MHCC97-L cells,enhanced their invasion and migration capacities,increased the IC50 of sorafenib,reduced the percentage of TUNEL-positive cells,and decreased the expression of proapoptotic ***,silencing MFN2 markedly induced the nuclear translocation ofβ-catenin,increasedβ-catenin acetylation levels and enhanced the expression of the downstream regulatory proteins Snail1 and Vimentin while inhibiting E-cadherin ***,overexpressing MFN2 reversed the effects observed in MHCC97-L cells mentioned *** results confirmed that silencing MFN2 activated theβ-catenin/epithelial-mesenchymal transition(EMT)pathway and reduced the sensitivity of cells to sorafenib,which could be reversed by XAV939 ***,overexpression of MFN2 inhibited theβ-catenin/EMT pathway and increased the sensitivity of cells to sorafenib,which could be altered by *** Low expression of MFN2 in HCC cells promotes the nuclear translocation ofβ-catenin,thereby activating the EMT pathway and mediating resistance to sorafenib.

关键词： mitofusin-2 epithelial-mesenchymal transition sorafenib resistance apoptosis hepatocellular carcinoma

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Endoplasmic reticulum stress improved chicken tenderness,promoted apoptosis and autophagy during postmortem ageing

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Food Science and Human Wellness 2024年第4期13卷 2141-2151页

作者： Yuwei chai Lin Chen Shuya Xiang Linxuan Wu Xuebo Liu Jun Luo Xianchao feng College of Food Science and Engineering Northwest A&F UniversityYangling 712100China College of Animal Science and Technology Northwest A&F UniversityYangling 712100China

In this study,endoplasmic reticulum(ER)stress inducer tunicamycin(TM)and inhibitor 4-phenylbutyric acid(4-PBA)were used to treat postmortem chicken breast muscle to investigate changes in tenderness and effects on apoptosis and autophagy during 5 days ***-induced ER stress reduced shear force,enhanced myofibril fragmentation index(MFI),disrupted myofibril structure,increased desmin degradation,and activatedμ-calpain and *** addition,TM-induced ER stress increased the expression of Bax,Bim,and cytochrome c,and decreased the expression of Bcl-x ***,TM-induced ER stress improved the conversion of LC3I to LC3II,raised the expression of Beclin-1,and decreased the expression of p62,PI3K,and m *** opposite results were observed after 4-PBA *** results suggested that ER stress could improve chicken tenderness,promote apoptosis and autophagy during chicken postmortem ageing.

关键词： Endoplasmic reticulum stress Tenderness Apoptosis Autophagy Chicken

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The determination of sedimentary environment and associated energy in deep-buried marine carbonates:insights from natural gamma ray spectrometry log

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Frontiers of Earth Science 2024年第1期18卷 204-218页

作者： Jingyan LIU Qian CHANG Junlong ZHANG Hui chai feng HE Yizan yanG Shiqiang XIA School of Energy Resources China University of Geosciences(Beijing)Beijing 100083China Exploration and Development Research Institute Daqing Oilfield CompanyPetroChinaDaqing 163712China China National Oil and Gas Exploration and Development Co. Ltd(CNODC)Beijing 100032China Beijing Research Institute of Uranium Geology Beijing 100029China College of Mining Engineering North China University of Science and TechnologyTangshan 063210China

It has always been challenging to determine the ancient sedimentary environment and associated energy in deep-buried marine *** energy represents the hydrodynamic conditions that existed when the carbonates were *** energy includes light and chemical energies in compounds and kinetic energy in currents and mass ***-buried marine carbonates deposited during the Ordovician depositional period in the eastern Tarim Basin result from a complex interplay of tectonics,sedimentation,and *** a result,determining the ancient sedimentary environment and associated energy is *** natural gamma-ray spectrometry(GRS)log(from 12 wells)is used in this paper to conduct studies on the sedimentary environment and associated energy in deep-buried marine *** findings show that the values of thorium(Th),uranium(U),potassium(K),and gamma-ray without uranium(KTh)in a natural GRS log can reveal lithological associations,mineral composition,diagenetic environment,stratigraphic water activity,and ancient climatic *** the Ordovician,quantitative analysis and determination of sedimentary environment energy are carried out using a comprehensive calculation of natural GRS log parameters in typical wells(penetrating through the Ordovician with cores and thin sections)of well GC4,well GC6,well GC7,and well *** results show that GRS log can determine different lithology associations in typical wells than a sieve residue ***,cores and thin sections can be used to validate the determination of lithology *** on the determination of lithology associations,the lithology associations that reflect the sedimentary environment and associated energy can be analyzed in a new ***,the sedimentary environment energy curve derived from a natural GRS log can reveal hydrodynamic fluctuations during depositional periods,which will aid in the discovery of carbonate reservoirs,establishing sequence stratigra

关键词： ancient sedimentary environment energy of sedimentary environment marine deep-buried carbonates natural GRS the Ordovician eastern Tarim Basin

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Sensing properties and mechanisms of LaF_(3)-Co_(3)O_(4) nanorods for low-concentration methanol detection

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Rare Metals 2024年第5期43卷 2193-2204页

作者： Xiao-Xi He Hong-feng chai Yi-Wen Zhou Ke-Wei Liu Ze-Xin Yu Chao Zhang College of Mechanical Engineering Yangzhou UniversityYangzhou225127China Institutefor Manufacturing Technologies of Ceramic Components and Composites(IMTCCC) University of Stuttgart70569 StuttgartGermany

Methanol is one of the characteristic gases that distinguish between healthy individuals and lung cancer(LC)lesions in exhaled human *** concentration in exhaled breath is generally below one part per million(1×10^(-6)).The second-phase composite is widely regarded as one of the methods to improve the gas-sensing perfor-mance of metal oxide semiconductor(MOS)*** this study,LaF_(3)-Co_(3)O_(4) was synthesized by a simple hydrothermal method to enhance its low-concentration methanol gas-sensing performance.5 at%LaF_(3)-Co_(3)O_(4) nanorods exhibited excellent methanol detection performance,including a wider linear detection concentration range(0.2×10^(-6)~5×10^(-6)),a response value exceeding 4.0 for 1×10^(-6)methanol at 275°C and 75%relative humidity(RH),long-term stability(maximum deviation within 15%over 2 weeks),and excellent *** mechanism of performance enhancement was studied using various techniques,and density functional *** special spinel structure of Co_(3)O_(4),the high ionic migration of F-in LaF_(3),the larger specific surface area of 5 at%LaF_(3)-Co_(3)O_(4) nanorods,and the generated crystal defects all explain the excellentmethanol gas-sensing *** work provides a novel route to prepare MOS composite materials for low-concentration methanol gas detection.

关键词： Gas sensor LaF_(3) Co_(3)O_(4) Methanol Lung cancer

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