检索结果-南通市图书馆

Rare Metals 2022年第11期41卷 3740-3751页

作者： yan-dong guo Ji-Cheng Jiang Jian Xie Xin Wang Jing-Ze Li dong-Huang Wang Ai-Jun Zhou School of Materials and Energy University of Electronic Science and Technology of ChinaChengdu611731China yangtze Delta Region Institute(Huzhou) University of Electronic Science and Technology of ChinaHuzhou313001China State Key Laboratory of Silicon Materials School of Materials Science and EngineeringZhejiang UniversityHangzhou310027China

Sodium manganese hexacyanoferrate(NaMnHCF)is a promising cathode material for sodiumion batteries(SIBs)due to its low cost and high energy *** Jahn-Teller effect of Mn,however,leads to the poor structural stability of NaMnHCF,resulting in undesired electrochemical ***,we developed a novel coating strategy and obtained a coreshell structured NaMnHCF through facile Na^(+)-Cs^(+)ion exchange,which naturally produced a robust and insoluble Cs-rich surface layer(CsMnHCF)with several nanometers in thickness on pristine *** is shown that the Csrich surface plays a positive role in the stability of the NaMnHCF structure by prohibiting the leakage of crystal water,stabilizing the solid-liquid interfaces,and solidifying crystal *** electrochemical performance of the core-shell NaMnHCF is dramatically improved with a discharge capacity of 76.3 mAh·g^(-1)after 1000 cycles at 1.0 C and a reversible capacity of 87.0 mAh·g^(-1)at 10.0 C,which is much superior to that of the pristine NaMnHCF with only 26.6 mAh·g^(-1)after 400 cycles and 31 mAh·g^(-1)at 10.0 *** work reports a new method for the synthesis of core-shell NaMnHCF and provides a novel perspective for the development of advanced NaMnHCF cathode for SIBs.

关键词： Sodium manganese hexacyanoferrate Ion-exchange Core-shell structure Surface modification Sodium-ion batteries

Determination of alcohol compounds using corona discharge ion mobility spectrometry

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Journal of Environmental Sciences 2007年第6期19卷 751-755页

作者： HAN Hai-yan HUANG guo-dong JIN Shun-ping ZHENG Pei-chao XU guo-hua LI Jian-quan WANG Hong-mei CHU yan-nan Laboratory of Environmental Spectroscopy and Key Laboratory of Environmental Optics and Technology Anhui Institute of Optics and Fine Mechanics Chinese Academy of Sciences Hefei 230031 China

Ion mobility spectrometry （IMS） is a very fast, highly sensitive, and inexpensive technique, it permits efficient monitoring of volatile organic compounds like alcohols. In this article, positive ion mobility spectra for six alcohol organic compounds have been systematically studied for the first time using a high-resolution IMS apparatus equipped with a discharge ionization source. Utilizing protonated water cluster ions （H2O）nH^＋ as the reactant ions and clean air as the drift gas, alcohol organic compounds, ethanol, 1- propanol, 2-propanol, 1-butanol, 1-pentanol and 2-octanol, all exhibit product ion characteristic peaks in their respective ion mobility spectrometry, that is a result of proton transfer reactions between the alcohols and reaction ions （H2O）nH^＋. The mixture of these alcohols, including two isomers, has been detected, and the results showed that they could be distinguished effectively in the ion mobility spectrum. The reduced mobility values have been determined, which are in very well agreement with the traditional ^63Ni-IMS experimental values. The exponential dilution method was used to calibrate the alcohol concentrations, and a detection limit available for the alcohols is in order of magnitude of a few ng/L.

关键词： alcohols VOCs ion mobility spectrometry proton transfer reaction

Isolation and Identification of Virus dsRNA from Strawberry Plants

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Agricultural Sciences in China 2007年第1期6卷 86-93页

作者： LI He DAI Hong-yan ZHANG Zhi-hong GAO Xiu-yan DU guo-dong ZHANG Xin-yu College of Horticulture Shenyang Agricultural University Shenyang 110161 P.R.China

The analysis of virus genome is based on nucleic acid isolation. The aims of this study were to develop a method for isolation and identification of virus double-stranded ribonucleic acid （dsRNA） and to elucidate the nucleotide sequences of strawberry virus. Using the modified method, virus dsRNA was extracted from strawberry virus indicator plants and cultivated strawberry plants and detected using agarose gel electrophoresis with ethidium bromide staining and reverse transcription-polymerase chain reaction （RT-PCR）. The quantity of virus dsRNA varied among strawberry cultivars. The quantity of dsRNA from in vitro plantlets was higher than that from the young leaves of field plants. For the field-grown plants, there was more dsRNA in the young leaves. Virus dsRNA extracted from strawberry plants was resistant to deoxyribonuclease Ⅰ （DNase Ⅰ）, but evidently, it became resistant to ribonuclease A （RNase A） only in the presence of 0.5 M NaCl. Its bands in agarose gel could be readily recycled using an agarose gel DNA purification kit. With RT-PCR, the segments of both strawberry mottle virus and Strawberry mild yellow edge virus genomes were amplified by using the virus dsRNA recycled from gel or treated with DNase Ⅰ /RNase A as templates. The system developed for dsRNA isolation and identification in strawberry plants laid a sound foundation for the work on genome analysis of strawberry virus isolates in China.

关键词： dsRNA virus strawberry isolation RT-PCR

Study of the Correlation of EGFR and K-RAS Gene Mutations with Its Protein Expression in Non-small Cell Lung Cancer

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Clinical oncology and cancer researeh 2010年第2期7卷 97-102页

作者： Huan-ling L UAN Lei-na SUN Na dong yan guo Bao-cun SUN Zhong-li ZHAN Department of Pathology of Tianjin Can-cer Hospital Tianjin Medical University Tianjin Key Laboratory of Cancer Prevention and Therapy Tianjin Diagnosis and Therapy Center of Lung Cancer Tianjin 300060 China.

OBJECTIVE To investigate gene mutations of epidermal growth factor receptor （EGFR） and K-RAS （Kirsten rat sarcoma viral oncogene） in Chinese patients with non-small cell lung cancer （NSCLC）, and study the correlation with its protein expression and its clinical significance on *** Detect the EGFR and K-RAS gene mutations status by gene sequencing and use the method of immunohistochemistry to detect EGFR and K-RAS protein *** The frequency of EGFR mutations was 33%, mainly located in exon 19 and exon 21. The frequency of K-RAS mutations was 5.5%, mainly located in codon 12. There was no case which both had EGFR and K-RAS mutations, suggesting a mutually exclusive relationship between the two. EGFR mutations are more common in adenocarcinomas （particularly those with bronchioloalveolar features）, nonsmokers and females. 16% were detected EGFR positive expression and had no correlation with EGFR mutation （P 〉 0.05）, but had significant correlation with mutation in exon 19 （P 〈 0.05）. The frequency of K-RAS positive expression was 52.5% and had no correlation with K-RAS mutation （P 〉 0.05）. Twelve （8 cases were protein-negative） out of 15 gefitinib-treated NSCLC patients with disease control carry EGFR *** EGFR protein expression has some correlation with exon 19 mutations. Combined detection of EGFR and K-RAS gene mutations can help clinicians to choose patients who may benefit from EGFR tyrosine kinase inhibitor （EGFR-TKI） and to predict the response and prognosis of gefitinib.

关键词： Epidermal growth factor receptor (EGFR) Kirstenrat sarcoma viral oncogene (K-RAS) Non-small cell lung cancer(NSCLC) EGFR tyrosine kinase inhibitor (EGFR-TKI).

我国近代学校体育的兴起(1901-1911年)

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北京体育大学学报 2005年第6期28卷 801-803页

作者：董艳国黑龙江大庆市八一农垦大学军体部黑龙江大庆163319

清末在新政和军国民主义及新教育思想传播的大背景下,各级各类学校开始了中国教育史上从未有过的体育教育,并且在体育师资的培养上做了一些工作。虽然具体实施的情形有好有坏,但是,清末体育教育的开创之功是极为重要的,并对后世发生了... 详细信息

清末在新政和军国民主义及新教育思想传播的大背景下,各级各类学校开始了中国教育史上从未有过的体育教育,并且在体育师资的培养上做了一些工作。虽然具体实施的情形有好有坏,但是,清末体育教育的开创之功是极为重要的,并对后世发生了相当大的影响。

关键词：学校体育近代清末体育教育中国

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程耀臣与国人所编首部俄文词典

福建师范大学学报（哲学社会科学版） 2009年第2期 108-112页

作者：阎国栋南开大学外国语学院天津300071

程耀臣是20世纪初中国著名的俄语专家,1917年以其编写的《华俄合璧商务大字典》结束了清代以来俄汉双语词典主要由俄国人编写的历史,开创了国人编纂俄语辞书的新时代,并在1925年出版由教育部审定颁布的《教育部审定增补华俄大字典》,在... 详细信息

程耀臣是20世纪初中国著名的俄语专家,1917年以其编写的《华俄合璧商务大字典》结束了清代以来俄汉双语词典主要由俄国人编写的历史,开创了国人编纂俄语辞书的新时代,并在1925年出版由教育部审定颁布的《教育部审定增补华俄大字典》,在中国俄语教育史上实有开拓之功。

关键词：程耀臣俄文词典俄语教育

Feasibility of Localizing in vivo Micro-devices with Electromagnetic Methods

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Journal of Shanghai Jiaotong university(Science) 2008年第5期13卷 559-561页

作者：郭旭东颜国正姜萍萍 School of Electronic Information and Electrical Engineering Shanghai Jiaotong University

In order to measure the location of medical micro-devices in the gastrointestinal tract, electro-magnetic methods were developed considering the magnetic permeability of human bodies. Two varieties of electromagnetic localization methods have been implemented: one uses direct current(DC) to generate the elec-tromagnetic field, and the other uses alternating current (AC). The two varieties of the localization principle were analyzed and relevant experiments were made. The experiments show that the alternating electromagnetic method acquires higher accuracy, higher stability and wider measurement range.

关键词： medical micro-devices position measurement electromagnetic field

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雷贝拉唑治疗胃食管反流病疗效观察

中国新药杂志 2006年第21期15卷 1876-1877页

作者：颜国栋福建泉州市第一医院消化内科泉州362000

目的:观察雷贝拉唑治疗胃食管反流病的临床疗效。方法:将60例胃食管反流病患者随机分为2组,雷贝拉唑组30例,服用雷贝拉唑10 mg,qd;对照组服用雷尼替丁150 mg,bid,早晚服用。疗程均为4周。结果:雷贝拉唑治疗组临床症状改善明显优于对照组... 详细信息

目的:观察雷贝拉唑治疗胃食管反流病的临床疗效。方法:将60例胃食管反流病患者随机分为2组,雷贝拉唑组30例,服用雷贝拉唑10 mg,qd;对照组服用雷尼替丁150 mg,bid,早晚服用。疗程均为4周。结果:雷贝拉唑治疗组临床症状改善明显优于对照组,并明显改善内镜下食管炎分级,且不良反应少。结论:雷贝拉唑治疗胃食管反流病疗效显著。

关键词：雷贝拉唑胃食管反流病食管分级

Effects of spironolactone on electrical and structural remodeling of atrium in congestive heart failure dogs

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Chinese Medical Journal 2008年第1期121卷 38-42页

作者： yanG Shu-sen HAN Wei ZHOU Hong-yan dong guo WANG Bai-chun HUO Hong WEI Na CAO Yong ZHOU guo XIU Chun-hong LI Wei-min Department of Cardiology First Clinical College of HarbinMedical University Harbin Heilongjiang 150001 China

Background Renin-angiotensin-aldosterone system has been demonstrated to be associated with both congestive heart failure （CHF） and atrial fibrillation （AF）. This study investigated the effects of spironolactone, a kind of aldosterone antagonist, on atrial electrical remodeling and fibrosis in CHF dogs induced by chronic rapid ventricular pacing. Methods Twenty one dogs were randomly divided into sham-operated group, control group, and spironolactone group. In control group and spironolactone group, dogs were ventricular paced at 220 beats per minute for 6 weeks. Additionally, spironolactone at 15 ***.d1 was given to dogs 1 week before rapid ventricular pacing until pacing stopped. Transthoracic and transoesophageal echocardiographic examinations were performed to detect structural and functional changes of the atrium. Swan2 Ganz floating catheters were used to measure hemadynamics variances. Atrial effective refractory period （AERP）, AERP dispersion （AERPd） conduction velocity （CV） were determined. The inducib atrial fibrosis was quantified with Masson staining. intra- and inter-atrium conduction time （CT） and intra-atrium ity and duration of AF were also measured in all groups. Finally, Results AERP did not change significantly after dogs were ventricular paced for 6 weeks. However, AERPd, intra- and inter-atrium CT increased significantly, and CV decreased apparently, which was negatively correlated to the atrial fibrosis （r=-0.74, P〈0.05）. Simultaneously, left atriums were enlarged and cardiac hemadynamics worsened in pacing dogs. Although spironolactone could not affect cardiac hemadynamics effectively, it can obviously improve left atrial ejection fraction （P〈0.05）. Spironolactone treatment did not alter AERP duration, but this medicine dramatically decreased AERPd （P〈0.05）, shortened intra- and inter-atrium conduction time （P〈0.05）, and increased atrium CV. Moreover, spironolactone decreased the inducibility and duration of AF （P〈0.05）, as well as atrial f

关键词： spironolactone heart failure cardiac remodeling fibrosis

Exploration of the efficacy and mechanism of treating head wind disease with the combination change of ginger volatile oil and gingerol by using content-weighted network pharmacology technology

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TMR Modern Herbal Medicine 2024年第1期7卷 43-56页

作者： Wei-Xiang Wang Fei yan Fei Luan Ya-Jun Shi Xiao-Fei Zhang dong-yan guo Bing-Tao Zhai Jun-Bo Zou Shaanxi Province Key Laboratory of New Drugs and Chinese Medicine Foundation Research College of PharmacyShaanxi University of Chinese MedicineXianyang 712046China

Background:Exploring the efficacy,potential components,and mechanism of the combination of ginger essential oil and gingerols in the treatment of head wind disease based on network pharmacology technology with content ***:The experimental groups were divided into:0:10,1:4,1:2,1:1,2:1,4:1,10:*** relative content(Ri)of the chemical constituents of ginger's volatile oil was determined using gas chromatography-mass spectrometry(GC-MS).Additionally,the physicochemical and biological property parameters(LogP,MDCK,PPB,MW)of the components were *** assess the quantitative effect of the components,a grading score was performed,and the quantitative effect index(Ki)was ***,the target effect index(Ti)was calculated by combining the component-target matching score(Fit score).Using these calculations,the target effect score A was determined under the influence of multiple components targeting different *** targets with A≥1000 were *** predict the targets related to head wind disease,the Comparative Toxicogenomics Database(https://***/),Gene Cards(https://***/),and Disgenet database(https://***/)were *** key targets,obtained from different proportions of ginger's volatile oil and gingerol,were intersected with the predicted *** facilitated network pharmacological analysis and verification of the ***:The content of volatile oil in ginger demonstrated an impact on key targets associated with the volatile oil *** specific combination of volatile oil consistently activated distinct pathways,with variations stemming from changes in *** testing revealed that different combinations of ginger's volatile oil and gingerol effectively alleviated migraine symptoms in ***:Through the application of content-weighted network pharmacology technology and pharmacodynamic verification,it was determined that altering the ratio between ginge

关键词： network pharmacology volatile oil of ginger weight of content head wind disease